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- PFE360 is subdivided into first dose and cross-over: PFE360 is a LRRK2 kinase inhibitor it was dosed at a concentration of 7.5 mg/kg in a cross-over design. The recordings were done in triplicate starting 1 hour after administration of PFE360 using only the blue light setting. The randomisation sequence for the dosing was - 0,1,1,1,1,0,1,0,0,0,0,1,1,0,0,1,0,1,0,0,0,0,1,0,1,1,1,1,1 on first dose 0=vehicle and 1=PFE360 and vice versa for cross-over
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