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PONE-D-22-26810

Title: Effects of Heterozygous Deletion of Autism-related Gene Cullin-3 in Mice

Description: This is a original dataset repository for manuscript # PONE-D-22-26810 published at PLOS ONE, including the Western blot (Figure 1 and Figure S1/S3), behavioral tests (Figure 2-4 and Figure S2, Supplementary material), Golgi staining (Figure 5), field recording (Figure 6), whole-cell patch clamp recording (Figure 7), proteomic analysis (figure 8 and proteomic raw data file .zip).

The figure files format are .pzfx, which can be open by Prism GraphPad: https://www.graphpad.com/features; these figure files including the raw data of these Western blots, behavioral tests, Golgi stainings, electrophysiological recordings etc. at Data tables; statistical analysis at Results; graphs plotted from these raw data at Graphs; figures made from these grpahs at Layouts.

Proteomic raw data file .zip can be uncompressed by WinRAR: https://www.win-rar.com/start.html?&L=0, which consists of upregulated and downregulated expressed proteins after Cul3 heterozygous deletion in mouse brains, a powerpoint .ppt that can be opened by Office powerpoint analyzed, explpained and summarized the Proteomic raw data.

Supplementary material is a .word that can be opened by Office Word, which including the figure legends of Figure S1-S3.

please contact qqxia@uab.edu if you have any questions on these data.