| Title |
Task-specific modulation of corticospinal neuron activity during motor learning |
| Authors |
Serradj,Najet;Burke Neurological Institute;ORCID: 0000-0002-2025-4011
Marino,Francesca;University of California, San Francisco;ORCID: 0000-0002-7899-4282
Moreno-López,Yunuen;Burke Neurological Institute;ORCID: 000-0002-4023-849X
Bernstein,Amanda;Burke Neurological Institute;ORCID: 0000-0002-6619-4878
Agger,Sydney;HAVAS Production Studios;ORCID: 0000-0002-4991-0609
Soliman,Marwa;Burke Neurological Institute;ORCID: 0000-0001-7118-4546
Sloan,Andrew;Vulintus, Inc., Lafayette, Colorado, USA;ORCID: 0000-0002-1205-0502
Hollis,Edmund;Burke Neurological Institute;ORCID: 0000-0002-4535-4668
|
| Description |
The learning of motor skills relies on plasticity of the primary motor cortex as task acquisition drives the remodeling of cortical motor networks. Large scale cortical remodeling of evoked motor outputs occurs in response to the learning of skilled, corticospinal-dependent behavior, but not simple, unskilled tasks. Here we determine the response of corticospinal neurons to both skilled and unskilled motor training and assess the role of corticospinal neuron activity in the execution of the trained behaviors.
|
| License |
Creative Commons CC0 1.0 Public Domain Dedication (https://creativecommons.org/publicdomain/zero/1.0/)
|
| References |
Serradj N, Marino F, et al. (2022) Preprint of study based on the data. arXiv. https://doi.org/10.1101/2021.03.22.436415 [https://doi.org/10.1101/2021.03.22.436415] (IsSupplementTo)
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| Funding |
National Institutes of Health DP2 NS106663
National Institutes of Health R03 NS103070
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| Keywords |
Neuroscience
Calcium Imaging
Motor Learning
|
| Resource Type |
Dataset
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