INS-disorders-publication/Supplementary_Material_Files_S3.json

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    {
      "abstract": "AIM OBJECTIVE Childhood sexual abuse (CSA) among women is an alarmingly prevalent traumatic experience that often leads to debilitating and treatment-refractory posttraumatic stress disorder (PTSD), raising the need for novel adjunctive therapies. Neuroimaging investigations systematically report that amygdala hyperactivity is the most consistent and reliable neural abnormality in PTSD and following childhood abuse, raising the potential of implementing volitional neural modulation using neurofeedback (NF) aimed at down-regulating amygdala activity. This study aimed to reliably probe limbic activity but overcome the limited applicability of functional magnetic resonance imaging (fMRI) NF by using a scalable electroencephalogram NF probe of amygdala-related activity, termed amygdala electrical-finger-print (amyg-EFP) in a randomized controlled trial.\nMETHOD METHODS Fifty-five women with CSA-PTSD who were in ongoing intensive trauma-focused psychotherapy for a minimum of 1\u2009year but still met Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) PTSD criteria were randomized to either 10 add-on sessions of amyg-EFP-NF training (test group) or continuing psychotherapy (control group). Participants were blindly assessed for PTSD symptoms before and after the NF training period, followed by self-reported clinical follow-up at 1, 3, and 6 months, as well as one session of amygdala real-time fMRI-NF before and after NF training period.\nRESULTS RESULTS Participants in the test group compared with the control group demonstrated a marginally significant immediate reduction in PTSD symptoms, which progressively improved during the follow-up period. In addition, successful neuromodulation during NF training was demonstrated.\nCONCLUSION CONCLUSIONS This feasibility study for patients with treatment-resistant CSA-PTSD indicates that amyg-EFP-NF is a viable and efficient intervention.",
      "authors": [
        "Fine, Naomi B",
        "Helpman, Liat",
        "Armon, Daphna Bardin",
        "Gurevitch, Guy",
        "Sheppes, Gal",
        "Seligman, Zivya",
        "Hendler, Talma",
        "Bloch, Miki"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1111/pcn.13591",
      "keywords": [
        "N fMRI",
        "@UI",
        "N PTSD",
        "N neuromodulation",
        "N childhood abuse",
        "N limbic activity",
        "#text"
      ],
      "number_of_pages": 10,
      "pages": "19-28",
      "publication": {
        "category": "Journal",
        "cite_score": 9.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1440-1819",
        "publisher": "Wiley-Blackwell Publishing Ltd",
        "sjr": 1.389,
        "snip": 1.754,
        "subject_areas": [
          "Neurology (clinical)",
          "Neuroscience (all)",
          "Psychiatry and Mental Health",
          "Neurology"
        ],
        "title": "Psychiatry and clinical neurosciences"
      },
      "publication_date": "2023-12-22",
      "selected": false,
      "title": "Amygdala-related electroencephalogram neurofeedback as add-on therapy for treatment-resistant childhood sexual abuse posttraumatic stress disorder: feasibility study.",
      "urls": []
    },
    {
      "abstract": "Background: Single-time non-invasive brain stimulation was carried out using the two-technique approach on a patient suffering from treatment-resistant depression. Five treatment sessions given at weekly intervals resulted in a significant improvement in the Patient Health Questionnaire-9 score for up to 6\u00c2 weeks. The findings of this study could pave the way for a more efficient less resource-intensive time- and budget-saving technique of employing non-invasive brain stimulation for patients with treatment-resistant depression by minimizing the number of stimulation sessions. Case presentation: A 67-year-old married non-Latino white American woman suffering from treatment-resistant depression received intermittent tetraburst stimulation in combination with transcranial direct current stimulation weekly for 5 consecutive weeks. Diagnostic transcranial magnetic stimulation showed an observable electrophysiological change. The patient reported a drastic improvement in Patient Health Questionnaire-9 score up until 6-week follow-up and expressed satisfaction with the treatment. Conclusions: This case study suggests that a streamlined protocol for using non-invasive brain stimulation could prove more effective for patients and healthcare providers in terms of safety in comparison to the present guidelines. \u00c2\u00a9 2023, BioMed Central Ltd., part of Springer Nature.",
      "authors": [
        "Wivatvongvana, P.",
        "Soonthornthum, C.",
        "Kitisak, K."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1186/s13256-023-04152-0",
      "keywords": [
        "PHQ-9",
        "iTBS",
        "TMS",
        "tDCS",
        "Treatment-resistant depression"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
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        "isbn": null,
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        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Journal of Medical Case Reports"
      },
      "publication_date": "2023-12-01",
      "selected": false,
      "title": "Intermittent tetraburst stimulation combined with transcranial direct current stimulation once weekly for treatment-resistant depression: a case report",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85173058143&origin=inward"
      ]
    },
    {
      "abstract": "The purpose of this study is to investigate how information content related to tourism in Indonesia can influence the intention of social media users to adopt recommendations related to environmental tourism destinations. This study adopts transactive memory systems (TMS), which are currently an important factor in information sharing. In social media, tourism information sharing activities occur, so social media can be said to be TMS. This paper discusses three measures used by TMS, namely specialisation, credibility, and coordination. This study uses an empirical analysis of 170 social media users. The data collected were analysed using the partial least square (PLS) method, a statistical analysis technique based on structural equation modelling (SEM). Our findings reveal that TMS credibility is positively related to community commitment and communication quality, likewise with TMS coordination, but not for TMS specialisation; it was not found to be related to communication commitment and communication quality. Other findings reveal a significant relationship between community commitment and communication quality on acceptance of recommendations from social media. Copyright \u00c2\u00a9 2024 Inderscience Enterprises Ltd.",
      "authors": [
        "Sihotang, D.M.",
        "Faisar, T.R.M.",
        "Saraswati, R.I.",
        "Naima, M.S.",
        "Santoso, S.M.",
        "Yuniarto, A.",
        "Hidayanto, A.N."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1504/IJIL.2024.135158",
      "keywords": [
        "transactive memory system",
        "tourism recommendations",
        "TMS",
        "social media"
      ],
      "number_of_pages": 15,
      "pages": "59-73",
      "publication": {
        "category": "Journal",
        "cite_score": 1.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "14718197",
        "publisher": "Inderscience Enterprises Ltd.",
        "sjr": 0.226,
        "snip": 0.394,
        "subject_areas": [
          "Education",
          "Management of Technology and Innovation"
        ],
        "title": "International Journal of Innovation and Learning"
      },
      "publication_date": "2023-12-01",
      "selected": false,
      "title": "Intention of social media users in adopting environmental tourism recommendations in Indonesia: transactive memory system perspective",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85179956441&origin=inward"
      ]
    },
    {
      "abstract": "Background: Multiple sclerosis (MS) is a degenerative disease of the central nervous system (CNS) that disrupts walking function and results in other debilitating symptoms. This study compares the effects of \u00e2\u0080\u0098task-oriented exercise\u00e2\u0080\u0099 against \u00e2\u0080\u0098generalized resistance and aerobic exercise\u00e2\u0080\u0099 and a \u00e2\u0080\u0098stretching control\u00e2\u0080\u0099 on walking and CNS function in people with MS (PwMS). We hypothesize that task-oriented exercise will enhance walking speed and related neural changes to a greater extent than other exercise approaches. Methods: This study is a single-blinded, three-arm randomized controlled trial conducted in Saskatchewan, Canada. Eligible participants are those older than 18 years of age with a diagnosis of MS and an expanded Patient-Determined Disease Steps (PDDS) score between 3 (\u00e2\u0080\u0098gait disability\u00e2\u0080\u0099) and 6 (\u00e2\u0080\u0098bilateral support\u00e2\u0080\u0099). Exercise interventions are delivered for 12 weeks (3 \u00c3\u0097 60-min per week) in-person under the supervision of a qualified exercise professional. Interventions differ in exercise approach, such that task-oriented exercise involves weight-bearing, walking-specific activities, while generalized resistance and aerobic exercise uses seated machine-based resistance training of major upper and lower body muscle groups and recumbent cycling, and the stretching control exercise involves seated flexibility and relaxation activities. Participants are allocated to interventions using blocked randomization that stratifies by PDDS (mild: 3\u00e2\u0080\u00934; moderate: 5\u00e2\u0080\u00936). Assessments are conducted at baseline, post-intervention, and at a six-week retention time point. The primary and secondary outcome measures are the Timed 25-Foot Walk Test and corticospinal excitability for the tibialis anterior muscles determined using transcranial magnetic stimulation (TMS), respectively. Tertiary outcomes include assessments of balance, additional TMS measures, blood biomarkers of neural health and inflammation, and measures of cardiorespiratory and musculoskeletal fitness. Discussion: A paradigm shift in MS healthcare towards the use of \u00e2\u0080\u009cexercise as medicine\u00e2\u0080\u009d was recently proposed to improve outcomes and alleviate the economic burden of MS. Findings will support this shift by informing the development of specialized exercise programming that targets walking and changes in corticospinal excitability in PwMS. Trial registration: ClinicalTrials.gov, NCT05496881, Registered August 11, 2022. https://classic.clinicaltrials.gov/ct2/show/NCT05496881 . Protocol amendment number: 01; Issue date: August 1, 2023; Primary reason for amendment: Expand eligibility to include people with all forms of MS rather than progressive forms of MS only. \u00c2\u00a9 2023, The Author(s).",
      "authors": [
        "Moslemi, Z.",
        "Toledo-Aldana, E.A.",
        "Baldwin, B.",
        "Donkers, S.J.",
        "Eng, J.J.",
        "Mondal, P.",
        "de Zepetnek, J.O.T.",
        "Buttigieg, J.",
        "Levin, M.C.",
        "Mang, C.S."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1186/s13102-023-00790-5",
      "keywords": [
        "Multiple sclerosis",
        "Motor function",
        "Transcranial magnetic stimulation",
        "Biomarkers",
        "Neurological rehabilitation"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "BMC Sports Science, Medicine and Rehabilitation"
      },
      "publication_date": "2023-12-01",
      "selected": false,
      "title": "Task-oriented exercise effects on walking and corticospinal excitability in multiple sclerosis: protocol for a randomized controlled trial",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85180230308&origin=inward"
      ]
    },
    {
      "abstract": "Rumination is a significant risk factor for psychopathology in adolescent girls and is associated with heightened and prolonged physiological arousal following social rejection. However, no study has examined how rumination relates to neural responses to social rejection in adolescent girls; thus, the current study aimed to address this gap. Adolescent girls (N = 116; ages 16.95\u00e2\u0080\u009319.09) self-reported on their rumination tendency and completed a social evaluation fMRI task where they received fictitious feedback (acceptance, rejection) from peers they liked or disliked. Rejection-related neural activity and subgenual anterior cingulate cortex (sgACC) connectivity were regressed on rumination, controlling for rejection sensitivity and depressive symptoms. Rumination was associated with distinctive neural responses following rejection from liked peers including increased neural activity in the precuneus, inferior parietal gyrus, dorsolateral prefrontal cortex, and supplementary motor area (SMA) and reduced sgACC connectivity with multiple regions including medial prefrontal cortex, precuneus and ventrolateral prefrontal cortex. Greater precuneus and SMA activity mediated the effect of rumination on slower response time to report emotional state after receiving rejection from liked peers. These findings provide clues for distinctive cognitive processes (e.g., mentalizing, conflict processing, memory encoding) following the receipt of rejection in girls with high levels of rumination. \u00c2\u00a9 2023",
      "authors": [
        "Yoon, L.",
        "Keenan, K.E.",
        "Hipwell, A.E.",
        "Forbes, E.E.",
        "Guyer, A.E."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1016/j.dcn.2023.101320",
      "keywords": [
        "Social rejection",
        "Default mode network",
        "Rumination",
        "sgACC",
        "fMRI",
        "Adolescence"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 8.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "18789293",
        "publisher": "Elsevier BV",
        "sjr": 1.792,
        "snip": 1.42,
        "subject_areas": [
          "Cognitive Neuroscience"
        ],
        "title": "Developmental Cognitive Neuroscience"
      },
      "publication_date": "2023-12-01",
      "selected": false,
      "title": "Hooked on a thought: Associations between rumination and neural responses to social rejection in adolescent girls",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85175535534&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND BACKGROUND Prior trials suggest that intravenous racemic ketamine is a highly effective for treatment-resistant depression (TRD), but phase 3 trials of racemic ketamine are needed.\nAIMS OBJECTIVE To assess the acute efficacy and safety of a 4-week course of subcutaneous racemic ketamine in participants with TRD. Trial registration: ACTRN12616001096448 at www.anzctr.org.au.\nMETHOD METHODS This phase 3, double-blind, randomised, active-controlled multicentre trial was conducted at seven mood disorders centres in Australia and New Zealand. Participants received twice-weekly subcutaneous racemic ketamine or midazolam for 4 weeks. Initially, the trial tested fixed-dose ketamine 0.5 mg/kg versus midazolam 0.025 mg/kg (cohort 1). Dosing was revised, after a Data Safety Monitoring Board recommendation, to flexible-dose ketamine 0.5-0.9 mg/kg or midazolam 0.025-0.045 mg/kg, with response-guided dosing increments (cohort 2). The primary outcome was remission (Montgomery-\u00c5sberg Rating Scale for Depression score \u226410) at the end of week 4.\nRESULTS RESULTS v P v P The final analysis (those who received at least one treatment) comprised 68 in cohort 1 (fixed-dose), 106 in cohort 2 (flexible-dose). Ketamine was more efficacious than midazolam in cohort 2 (remission rate 19.6% . 2.0%; OR = 12.1, 95% CI 2.1-69.2,  = 0.005), but not different in cohort 1 (remission rate 6.3% . 8.8%; OR = 1.3, 95% CI 0.2-8.2,  = 0.76). Ketamine was well tolerated. Acute adverse effects (psychotomimetic, blood pressure increases) resolved within 2 h.\nCONCLUSIONS CONCLUSIONS Adequately dosed subcutaneous racemic ketamine was efficacious and safe in treating TRD over a 4-week treatment period. The subcutaneous route is practical and feasible.",
      "authors": [
        "Loo, Colleen",
        "Glozier, Nick",
        "Barton, David",
        "Baune, Bernhard T",
        "Mills, Natalie T",
        "Fitzgerald, Paul",
        "Glue, Paul",
        "Sarma, Shanthi",
        "Galvez-Ortiz, Veronica",
        "Hadzi-Pavlovic, Dusan",
        "Alonzo, Angelo",
        "Dong, Vanessa",
        "Martin, Donel",
        "Nikolin, Stevan",
        "Mitchell, Philip B",
        "Berk, Michael",
        "Carter, Gregory",
        "Hackett, Maree",
        "Leyden, John",
        "Hood, Sean",
        "Somogyi, Andrew A",
        "Lapidus, Kyle",
        "Stratton, Elizabeth",
        "Gainsford, Kirsten",
        "Garg, Deepak",
        "Thornton, Nicollette L R",
        "Fourrier, C\u00e9lia",
        "Richardson, Karyn",
        "Rozakis, Demi",
        "Scaria, Anish",
        "Mihalopoulos, Cathrine",
        "Chatterton, Mary Lou",
        "McDonald, William M",
        "Boyce, Philip",
        "Holtzheimer, Paul E",
        "Kozel, F Andrew",
        "Riva-Posse, Patricio",
        "Rodgers, Anthony"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1192/bjp.2023.79",
      "keywords": [
        "N neuroscience",
        "D016428 Journal Article",
        "N major depressive disorder",
        "N clinical drug studies",
        "N affective disorders.",
        "D017428 Clinical Trial, Phase III",
        "D016449 Randomized Controlled Trial",
        "D016448 Multicenter Study",
        "N Ketamine/esketamine"
      ],
      "number_of_pages": 9,
      "pages": "533-541",
      "publication": {
        "category": "Journal",
        "cite_score": 12.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1472-1465",
        "publisher": "Royal College of Psychiatrists",
        "sjr": 2.597,
        "snip": 2.644,
        "subject_areas": [
          "Psychiatry and Mental Health"
        ],
        "title": "The British journal of psychiatry : the journal of mental science"
      },
      "publication_date": "2023-12-01",
      "selected": false,
      "title": "Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial.",
      "urls": []
    },
    {
      "abstract": "BACKGROUND BACKGROUND This meta-analysis (PROSPERO-ID: CRD42022362962), pooled effect estimates of outcomes, from placebo-controlled randomized clinical trials (RCTs) examining bupropion efficacy and safety for amphetamine-type stimulant use disorder (ATSUD) treatment.\nMETHOD METHODS Electronic databases were searched for records published to October 31st, 2022, including MEDLINE, CINAHL, PsycINFO, EBM Reviews, EMBASE, PubMed, Web of Science, trial registries. Inclusion criteria were RCTs comparing bupropion to placebo in ATSUD. Cochrane RoB2 tool and GRADE evidence certainty assessment were employed. Outcomes included amphetamine-type stimulant (ATS) use by urinalysis, retention in treatment, treatment adherence, ATS craving, addiction severity, depressive symptom severity, drop-out following adverse events (AEs), and serious AEs. Random-effect meta-analysis was conducted presenting standardized mean difference (SMD), risk ratio (RR), and risk difference (RD).\nRESULTS RESULTS Eight RCTs (total N=1239 participants) were included. Bupropion compared to placebo was associated with reduced ATS use (RR: 0.90; 95% CI: 0.84, 0.96), end-of-treatment ATS craving (SMD: -0.38; 95%CI: -0.63, -0.13), and adherence (RR: 0.91; 95%CI: 0.84, 0.99). Subgroup analysis showed greater reduction in ATS use with longer trial duration (12 weeks) (RR: 0.85; 95%CI: 0.78, 0.93) and greater reduction in end-of-treatment ATS craving in studies with mixed ATS use frequency (SMD: -0.46; 95%CI: -0.70, -0.22) and male-only samples (SMD: -1.26; 95%CI: -1.87, -0.65).\nCONCLUSION CONCLUSIONS Bupropion showed a significant modest reduction in ATS use and ATS craving (both rated as very low-quality evidence), larger in males (craving), and with longer treatment (ATS use). These results may inform future studies. More research is warranted on who might benefit from bupropion as ATSUD treatment.",
      "authors": [
        "Bakouni, Hamzah",
        "Sharafi, Heidar",
        "Bahremand, Arash",
        "Drouin, Sarah",
        "Ziegler, Daniela",
        "Bach, Paxton",
        "Le Foll, Bernard",
        "Sch\u00fctz, Christian G",
        "Tardelli, Vitor",
        "Ezard, Nadine",
        "Siefried, Krista",
        "Jutras-Aswad, Didier"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.drugalcdep.2023.111018",
      "keywords": [
        "N Methamphetamine",
        "D016428 Journal Article",
        "N Treatment",
        "D016454 Review",
        "N Pharmacotherapy",
        "N Meta-analysis",
        "N Amphetamine",
        "D017418 Meta-Analysis",
        "N Amphetamine use disorder",
        "N Bupropion",
        "D000078182 Systematic Review"
      ],
      "number_of_pages": null,
      "pages": "111018",
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1879-0046",
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Drug and alcohol dependence"
      },
      "publication_date": "2023-11-04",
      "selected": false,
      "title": "Bupropion for treatment of amphetamine-type stimulant use disorder: A systematic review and meta-analysis of placebo-controlled randomized clinical trials.",
      "urls": []
    },
    {
      "abstract": "The purpose of this study was to determine the effect of the Cz of high-definition 5-channel tDCS (HD-tDCS) on social function in 4\u00e2\u0080\u009312 years-old children with autism spectrum disorder (ASD). This study was a randomized, double-blind, pseudo-controlled trial in which 45 ASD children were recruited and divided into three groups with sex, age, and rehabilitation treatment as control variables. Each group of 15 children with ASD was randomly administered active HD-tDCS with the Cz as the central anode, active HD-tDCS with the left dorsolateral prefrontal cortex (F3) as the central anode, and sham HD-tDCS with the Cz as the central anode with 14 daily sessions in 3 weeks. The Social Responsiveness Scale Chinese Version (SRS-Chinese Version) was compared 1 week after stimulation with values recorded 1 week prior to stimulation. At the end of treatment, both the anodal Cz and anodal left DLFPC tDCS decreased the measures of SRS-Chinese Version. The total score of SRS-Chinese Version decreased by 13.08%, social cognition decreased by 18.33%, and social communication decreased by 10.79%, which were significantly improved over the Cz central anode active stimulation group, especially in children with young age, and middle and low function. There was no significant change in the total score and subscale score of SRS-Chinese Version over the Cz central anode sham stimulation group. In the F3 central anode active stimulation group, the total score of SRS-Chinese Version decreased by 13%, autistic behavior decreased by 19.39%, and social communication decreased by 14.39%, which were all significantly improved. However, there was no significant difference in effect between the Cz and left DLPFC stimulation conditions. HD-tDCS of the Cz central anode may be an effective treatment for social dysfunction in children with ASD. \u00c2\u00a9 2023 International Society for Autism Research and Wiley Periodicals LLC.",
      "authors": [
        "Wang, Y.",
        "Wang, F.",
        "Kong, Y.",
        "Gao, T.",
        "Zhu, Q.",
        "Han, L.",
        "Sun, B.",
        "Guan, L.",
        "Zhang, Z.",
        "Qian, Y.",
        "Xu, L.",
        "Li, Y.",
        "Fang, H.",
        "Jiao, G.",
        "Ke, X."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1002/aur.3018",
      "keywords": [
        "high definition 5-channel transcranial direct current stimulation (HD-tDCS)",
        "social dysfunction",
        "vertex (Cz)",
        "autism spectrum disorder (ASD)"
      ],
      "number_of_pages": 14,
      "pages": "2035-2048",
      "publication": {
        "category": "Journal",
        "cite_score": 7.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "19393792",
        "publisher": "John Wiley & Sons Inc.",
        "sjr": 1.323,
        "snip": 1.588,
        "subject_areas": [
          "Genetics (clinical)",
          "Neurology (clinical)",
          "Neuroscience (all)"
        ],
        "title": "Autism Research"
      },
      "publication_date": "2023-10-01",
      "selected": true,
      "title": "High definition transcranial direct current stimulation of the Cz improves social dysfunction in children with autism spectrum disorder: A randomized, sham, controlled study",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85170653066&origin=inward"
      ]
    },
    {
      "abstract": "Effective connectivity based on functional magnetic resonance imaging (fMRI) allows assessing directions of interaction between brain regions. For real-time fMRI, we compared models of positive social emotion regulation based on a network involving the bilateral amygdala, dorsomedial prefrontal, and subgenual anterior cingulate cortex. The top-down regulation model implied modulation of the dorsomedial prefrontal cortex exerted onto other regions, while the bottom-up model implied the inverse modulation. The validity of model calculations was tested using the data from three healthy volunteers who imagined positive interactions with people in presented photos (stimuli). We confirmed the dominance of the top-down model and evaluated the number and duration of iterations required for model estimations. The study shows the applicability of the four-node effective connectivity models for regulation of positive social emotions using real-time fMRI, e.g., for neurofeedback applications. \u00c2\u00a9 2023, Springer Science+Business Media, LLC, part of Springer Nature.",
      "authors": [
        "Bezmaternykh, D D",
        "Mel'nikov, M E",
        "Petrovskii, E D",
        "Mazhirina, K G",
        "Savelov, A A",
        "Kalgin, K V",
        "Shtark, M B",
        "Koush, Y A"
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1007/s10517-023-05892-1",
      "keywords": [
        "@UI",
        "N positive social emotion regulation",
        "N real-time functional MRI",
        "N effective connectivity",
        "N dynamic causal modeling",
        "#text"
      ],
      "number_of_pages": 5,
      "pages": "487-491",
      "publication": {
        "category": "Journal",
        "cite_score": 1.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1573-8221",
        "publisher": "Springer New York",
        "sjr": 0.231,
        "snip": 0.353,
        "subject_areas": [
          "Biochemistry, Genetics and Molecular Biology (all)"
        ],
        "title": "Bulletin of experimental biology and medicine"
      },
      "publication_date": "2023-09-28",
      "selected": false,
      "title": "Effective Connectivity of the Bilateral Amygdala, Dorsomedial Prefrontal, and Subgenual Anterior Cingulate Cortices: Feasibility of Positive Social Emotion Regulation Models for Real-Time Functional Magnetic Resonance Imaging.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85172803292&origin=inward"
      ]
    },
    {
      "abstract": "In the STAR*D study, the efficacy of treatments for major depression was examined. It was found that, while many responded to the initial antidepressant treatment, only 30% of participants achieved complete remission. Concerning treatment resistance in depression, there is a recent distinction emerging between treatment-resistant depression (TRD) and difficult-to-treat depression (DTD). Historically, TRD and DTD have been conflated, but it is essential to recognize them as separate entities. While TRD is characterized by a patient's inadequate response to two or more consecutive antidepressant treatments given for an adequate duration and dosage without achieving acceptable therapeutic effects, DTD describes a clinical category where patients do not achieve full symptom control despite various therapeutic approaches. The recent shift in perspective proposes a more integrated approach for DTD, encompassing psychosocial, biological, and interactive factors. This multifactorial model calls for a multidisciplinary therapeutic intervention, not restricted to pharmacological treatments but also including psychotherapy, neurostimulation, and social interventions. Informing professionals and the general public about the significance of this new approach could mitigate the stigma associated with depression and enhance the quality of care. The future challenge will involve a deeper clinical understanding of DTD and its optimal management by refining available treatments.",
      "authors": [
        "Paganin, Walter"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1192/j.eurpsy.2023.2448",
      "keywords": [
        "@UI",
        "N multidisciplinary",
        "N difficult-to-treat depression",
        "N clinical management",
        "N treatment-resistant depression",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "e73",
      "publication": {
        "category": "Journal",
        "cite_score": 8.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1778-3585",
        "publisher": "Cambridge University Press",
        "sjr": 1.993,
        "snip": 1.874,
        "subject_areas": [
          "Psychiatry and Mental Health"
        ],
        "title": "European psychiatry : the journal of the Association of European Psychiatrists"
      },
      "publication_date": "2023-09-08",
      "selected": false,
      "title": "Viewpoint: Difficult-to-treat depression versus treatment-resistant depression: A new integrative perspective for managing depression.",
      "urls": []
    },
    {
      "abstract": "Epilepsy is a complex neurological disorder affecting millions worldwide, with a substantial number of patients facing drug-resistant epilepsy. This comprehensive review explores innovative therapies for epilepsy management, focusing on their principles, clinical evidence, and potential applications. Traditional antiseizure medications (ASMs) form the cornerstone of epilepsy treatment, but their limitations necessitate alternative approaches. The review delves into cutting-edge therapies such as responsive neurostimulation (RNS), vagus nerve stimulation (VNS), and deep brain stimulation (DBS), highlighting their mechanisms of action and promising clinical outcomes. Additionally, the potential of gene therapies and optogenetics in epilepsy research is discussed, revealing groundbreaking findings that shed light on seizure mechanisms. Insights into cannabidiol (CBD) and the ketogenic diet as adjunctive therapies further broaden the spectrum of epilepsy management. Challenges in achieving seizure control with traditional therapies, including treatment resistance and individual variability, are addressed. The importance of staying updated with emerging trends in epilepsy management is emphasized, along with the hope for improved therapeutic options. Future research directions, such as combining therapies, AI applications, and non-invasive optogenetics, hold promise for personalized and effective epilepsy treatment. As the field advances, collaboration among researchers of natural and synthetic biochemistry, clinicians from different streams and various forms of medicine, and patients will drive progress toward better seizure control and a higher quality of life for individuals living with epilepsy. \u00c2\u00a9 2023 by the authors.",
      "authors": [
        "Ghosh, S.",
        "Sinha, J.K.",
        "Ghosh, S.",
        "Sharma, H.",
        "Bhaskar, R.",
        "Narayanan, K.B."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3390/brainsci13091305",
      "keywords": [
        "personalized therapy",
        "optogenetics",
        "drug-resistant epilepsy",
        "seizure mechanisms",
        "gene editing",
        "treatment resistance",
        "cannabinoids",
        "neurostimulation"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Brain Sciences"
      },
      "publication_date": "2023-09-01",
      "selected": false,
      "title": "A Comprehensive Review of Emerging Trends and Innovative Therapies in Epilepsy Management",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85172288325&origin=inward"
      ]
    },
    {
      "abstract": "Is there a way improve our ability to understand the minds of others? Towards addressing this question, here, we conducted a single-arm, proof-of-concept study to evaluate whether real-time fMRI neurofeedback (rtfMRI-NF) from the temporo-parietal junction (TPJ) leads to volitional control of the neural network subserving theory of mind (ToM; the process by which we attribute and reason about the mental states of others). As additional aims, we evaluated the strategies used to self-regulate the network and whether volitional control of the ToM network was moderated by participant characteristics and associated with improved performance on behavioral measures. Sixteen participants underwent fMRI while completing a task designed to individually-localize the TPJ, and then three separate rtfMRI-NF scans during which they completed multiple runs of a training task while receiving intermittent, activation-based feedback from the TPJ, and one run of a transfer task in which no neurofeedback was provided. Region-of-interest analyses demonstrated volitional control in most regions during the training tasks and during the transfer task, although the effects were smaller in magnitude and not observed in one of the neurofeedback targets for the transfer task. Text analysis demonstrated that volitional control was most strongly associated with thinking about prior social experiences when up-regulating the neural signal. Analysis of behavioral performance and brain-behavior associations largely did not reveal behavior changes except for a positive association between volitional control in RTPJ and changes in performance on one ToM task. Exploratory analysis suggested neurofeedback-related learning occurred, although some degree of volitional control appeared to be conferred with the initial self-regulation strategy provided to participants (i.e., without the neurofeedback signal). Critical study limitations include the lack of a control group and pre-rtfMRI transfer scan, which prevents a more direct assessment of neurofeedback-induced volitional control, and a small sample size, which may have led to an overestimate and/or unreliable estimate of study effects. Nonetheless, together, this study demonstrates the feasibility of training volitional control of a social cognitive brain network, which may have important clinical applications. Given the study's limitations, findings from this study should be replicated with more robust experimental designs. \u00c2\u00a9 2023 The Author(s)",
      "authors": [
        "Saxena, Abhishek",
        "Shovestul, Bridget J",
        "Dudek, Emily M",
        "Reda, Stephanie",
        "Venkataraman, Arun",
        "Lamberti, J Steven",
        "Dodell-Feder, David"
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1016/j.neuroimage.2023.120334",
      "keywords": [
        "D016428 Journal Article",
        "N Theory of mind",
        "N Real-time fMRI",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Neurofeedback",
        "N Social neuroscience",
        "N Temporo-parietal junction",
        "N Social cognition"
      ],
      "number_of_pages": null,
      "pages": "120334",
      "publication": {
        "category": "Journal",
        "cite_score": 11.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1095-9572",
        "publisher": "Academic Press Inc.",
        "sjr": 2.512,
        "snip": 1.782,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Neurology"
        ],
        "title": "NeuroImage"
      },
      "publication_date": "2023-08-15",
      "selected": false,
      "title": "Training volitional control of the theory of mind network with real-time fMRI neurofeedback.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85168414226&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND BACKGROUND Reducing avoidable nursing home (NH)-to-hospital transfers of residents with Alzheimer disease or a related dementia (ADRD) has become a national priority due to the physical and emotional toll it places on residents and the high costs to Medicare and Medicaid. Technologies supporting the use of clinical text messages (TMs) could improve communication among health care team members and have considerable impact on reducing avoidable NH-to-hospital transfers. Although text messaging is a widely accepted mechanism of communication, clinical models of care using TMs are sparsely reported in the literature, especially in NHs. Protocols for assessing technologies that integrate TMs into care delivery models would be beneficial for end users of these systems. Without evidence to support clinical models of care using TMs, users are left to design their own methods and protocols for their use, which can create wide variability and potentially increase disparities in resident outcomes.\nOBJECTIVE OBJECTIVE Our aim is to describe the protocol of a study designed to understand how members of the multidisciplinary team communicate using TMs and how salient and timely communication can be used to avert poor outcomes for NH residents with ADRD, including hospitalization.\nMETHODS METHODS This project is a secondary analysis of data collected from a Centers for Medicare & Medicaid Services (CMS)-funded demonstration project designed to reduce avoidable hospitalizations for long-stay NH residents. We will use two data sources: (1) TMs exchanged among the multidisciplinary team across the 7-year CMS study period (August 2013-September 2020) and (2) an adapted acute care transfer tool completed by advanced practice registered nurses to document retrospective details about NH-to-hospital transfers. The study is guided by an age-friendly model of care called the 4Ms (What Matters, Medications, Mentation, and Mobility) framework. We will use natural language processing, statistical methods, and social network analysis to generate a new ontology and to compare communication patterns found in TMs occurring around the time NH-to-hospital transfer decisions were made about residents with and without ADRD.\nRESULTS RESULTS After accounting for inclusion and exclusion criteria, we will analyze over 30,000 TMs pertaining to over 3600 NH-to-hospital transfers. Development of the 4M ontology is in progress, and the 3-year project is expected to run until mid-2025.\nCONCLUSIONS CONCLUSIONS To our knowledge, this project will be the first to explore the content of TMs exchanged among a multidisciplinary team of care providers as they make decisions about NH-to-hospital resident transfers. Understanding how the presence of evidence-based elements of high-quality care relate to avoidable hospitalizations among NH residents with ADRD will generate knowledge regarding the future scalability of behavioral interventions. Without this knowledge, NHs will continue to rely on ineffective and outdated communication methods that fail to account for evidence-based elements of age-friendly care.\nINTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID) UNASSIGNED DERR1-10.2196/50231.",
      "authors": [
        "Powell, Kimberly R",
        "Popescu, Mihail",
        "Lee, Suhwon",
        "Mehr, David R",
        "Alexander, Gregory L"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.2196/50231",
      "keywords": [
        "N nursing homes",
        "N age-friendly health systems",
        "N communication",
        "N older adults",
        "#text",
        "N Alzheimer disease",
        "N dementia",
        "@UI"
      ],
      "number_of_pages": null,
      "pages": "e50231",
      "publication": {
        "category": "Journal",
        "cite_score": 2.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1929-0748",
        "publisher": "JMIR Publications Inc.",
        "sjr": 0.528,
        "snip": 0.631,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "JMIR research protocols"
      },
      "publication_date": "2023-08-09",
      "selected": false,
      "title": "Examining the Use of Text Messages Among Multidisciplinary Care Teams to Reduce Avoidable Hospitalization of Nursing Home Residents with Dementia: Protocol for a Secondary Analysis.",
      "urls": []
    },
    {
      "abstract": "Tobacco smoking is a significant determinant of preventable morbidity and mortality worldwide. It is now possible to modulate the activity of the neurocircuitry associated with nicotine dependence using repetitive Transcranial Magnetic Stimulation (rTMS), a non-invasive neurostimulation approach, which has recently demonstrated efficacy in clinical trials and received regulatory approval in the US and Canada. However there remains a paucity of replication studies and real-world patient effectiveness data as access to this intervention is extremely limited. There are a number of unique challenges related to the delivery of rTMS that need to be addressed prior to widespread adoption and implementation of this treatment modality for smoking cessation. In this paper, we review the accessibility, scientific, technological, economical, and social challenges that remain before this treatment can be translated into clinical practice. By addressing these remaining barriers and scientific challenges with rTMS for smoking cessation and delineating implementation strategies, we can greatly reduce the burden of tobacco-related disease worldwide. \u00c2\u00a9 2023 Elsevier B.V.",
      "authors": [
        "Tang, V.M.",
        "Goud, R.",
        "Zawertailo, L.",
        "Selby, P.",
        "Coroiu, A.",
        "Sloan, M.E.",
        "Chenoweth, M.J.-A.",
        "Buchman, D.",
        "Ibrahim, C.",
        "Blumberger, D.M.",
        "Foll, B.L."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1016/j.psychres.2023.115340",
      "keywords": [
        "Smoking",
        "Nicotine",
        "Brain stimulation",
        "Tobacco",
        "Repetitive transcranial magnetic stimulation"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 13.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "01651781",
        "publisher": "Elsevier Ireland Ltd",
        "sjr": 2.139,
        "snip": 2.134,
        "subject_areas": [
          "Biological Psychiatry",
          "Psychiatry and Mental Health"
        ],
        "title": "Psychiatry Research"
      },
      "publication_date": "2023-08-01",
      "selected": false,
      "title": "Repetitive transcranial magnetic stimulation for smoking cessation: Next steps for translation and implementation into clinical practice",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85165361459&origin=inward"
      ]
    },
    {
      "abstract": "3 2 3 2 3 2 3 2 3 2 3 2 3 2 3 2 3 2 3 2 In-stent restenosis and thrombosis remain to be long-term challenges in coronary stenting procedures. The objective of this study was to evaluate the in vitro biological responses of trimethylsilane (TMS) plasma nanocoatings modified with NH /O (2:1 molar ratio) plasma post-treatment (TMS\u2009+\u2009NH /O nanocoatings) on cobalt chromium (CoCr) alloy L605 coupons, L605 stents, and 316L stainless steel (SS) stents. Surface properties of the plasma nanocoatings with up to 2-year aging time were characterized by wettability assessment and x-ray photoelectron spectroscopy (XPS). It was found that TMS\u2009+\u2009NH /O nanocoatings had a surface composition of 41.21\u2009\u00b1\u20091.06\u2009at% oxygen, 31.90\u2009\u00b1\u20091.08\u2009at% silicon, and 24.12\u2009\u00b1\u20091.7\u2009at% carbon, and very small but essential amount of 2.77\u2009\u00b1\u20090.18\u2009at% nitrogen. Surface chemical stability of the plasma coatings was noted with persistent O/Si atomic ratio of 1.292-1.413 and N/Si atomic ratio of ~0.087 through 2\u2009years. The in vitro biological responses of plasma nanocoatings were studied by evaluating the cell proliferation and migration of porcine coronary artery endothelial cells (PCAECs) and smooth muscle cells (PCASMCs). 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) assay results revealed that, after 7-day incubation, TMS\u2009+\u2009NH /O nanocoatings maintained a similar level of PCAEC proliferation while showing a decrease in the viability of PCASMCs by 73\u2009\u00b1\u200919% as compared with uncoated L605 surfaces. Cell co-culture of PCAECs and PCASMCs results showed that, the cell ratio of PCAEC/PCASMC on TMS\u2009+\u2009NH /O nanocoating surfaces was 1.5-fold higher than that on uncoated L605 surfaces, indicating enhanced selectivity for promoting PCAEC growth. Migration test showed comparable PCAEC migration distance for uncoated L605 and TMS\u2009+\u2009NH /O nanocoatings. In contrast, PCASMC migration distance was reduced nearly 8.5-fold on TMS\u2009+\u2009NH /O nanocoating surfaces as compared to the uncoated L605 surfaces. Platelet adhesion test using porcine whole blood showed lower adhered platelets distribution (by 70\u2009\u00b1\u200916%), reduced clotting attachment (by 54\u2009\u00b1\u200912%), and less platelet activation on TMS\u2009+\u2009NH /O nanocoating surfaces as compared with the uncoated L605 controls. It was further found that, under shear stress conditions of simulated blood flow, TMS\u2009+\u2009NH /O nanocoating significantly inhibited platelet adhesion compared to the uncoated 316L SS stents and TMS nanocoated 316L SS stents. These results indicate that TMS\u2009+\u2009NH /O nanocoatings are very promising in preventing both restenosis and thrombosis for coronary stent applications.",
      "authors": [
        "Phan, ThiThuHa",
        "Jones, John E",
        "Chen, Meng",
        "Strawn, T L",
        "Khoukaz, Hekmat B",
        "Ji, Yan",
        "Kumar, Arun",
        "Bowles, Douglas K",
        "Fay, William P",
        "Yu, Qingsong"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1002/jbm.a.37587",
      "keywords": [
        "D016428 Journal Article",
        "N restenosis and thrombosis prevention",
        "D052061 Research Support, N.I.H., Extramural",
        "N plasma nanocoatings",
        "N platelet adhesion",
        "N coronary stent",
        "N cell migration"
      ],
      "number_of_pages": 13,
      "pages": "1768-1780",
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1552-4965",
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Journal of biomedical materials research. Part A"
      },
      "publication_date": "2023-07-19",
      "selected": false,
      "title": "In vitro biological responses of plasma nanocoatings for coronary stent applications.",
      "urls": []
    },
    {
      "abstract": "Symptoms of overactive bladder syndrome (OAB), including urinary incontinence, affect a person's quality of life and cause many personal, social and economic problems. Patients were randomly divided into three groups and received transcutaneous tibial nerve stimulation (cTTNS) with fixed parameters or with variable parameters (vTTNS) and Solifenacin drug. The main outcomes including quality of life questionnaire and OAB score and other secondary outcomes were evaluated before and after treatment for 6 weeks. ANOVA test did not show any significant difference between the three groups in quality of life score (p=0.672), OAB symptom score (p=0.159) and incontinence severity (p=0.422). The t-test demonstrated that the post treatment average quality of life score, OAB score, and incontinence severity were significantly different when compared with before treatment in all three groups (p < 0.05). All three methods were effective in treating symptoms of OAB. However, based on the clinical symptoms, cTTNS is recommended as a preferred and acceptable and safe strategy for the treatment of OAB in women over 50 years old.",
      "authors": [
        "Radinmehr, Hojjat",
        "Radnia, Nahid",
        "Tabatabaei, Azade",
        "Asadi, Mohammad Reza",
        "Rahbar, Soulmaz",
        "Talimkhani, Ailin",
        "Irani, Amin Doosti",
        "Hajvalie, Gholam Reza"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.4081/ejtm.2023.11358",
      "keywords": [],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 3.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2037-7452",
        "publisher": "PagePress Publications",
        "sjr": 0.397,
        "snip": 0.673,
        "subject_areas": [
          "Neurology (clinical)",
          "Molecular Biology",
          "Cell Biology",
          "Orthopedics and Sports Medicine"
        ],
        "title": "European journal of translational myology"
      },
      "publication_date": "2023-06-20",
      "selected": false,
      "title": "Transcutaneous tibial neurostimulation and Solifenacin in urgent incontinence of postmenopausal women.",
      "urls": []
    },
    {
      "abstract": "BACKGROUND UNASSIGNED Stroke survivors often exhibit low motivation for rehabilitation, hindering their ability to effectively complete rehabilitation training task effectively and participate in daily activities actively. Reward strategies have been identified as an effective method for boosting rehabilitation motivation, but their long-term efficacy remains uncertain. Transcranial direct current stimulation (tDCS) has been recognized as a technique that facilitates plastic changes and functional reorganization of cortical areas. Particularly, tDCS can improve the functional connectivity between brain regions associated with goal-directed behavior when applied to the left dorsolateral prefrontal cortex (dlPFC). Combing reward strategies with tDCS (RStDCS) has been shown to motivate healthy individuals to exert more effort in task performance. However, research exploring the combined and sustained effects of these strategies on rehabilitation motivation in stroke survivors is lacking.\nMETHODS AND DESIGN UNASSIGNED Eighty-seven stroke survivors with low motivation and upper extremity dysfunction will be randomized to receive either conventional treatment, RS treatment, or RStDCS treatment. The RStDCS group will receive reward strategies combined with anodal tDCS stimulation of the left dlPFC. The RS group will receive reward strategies combined with sham stimulation. The conventional group will receive conventional treatment combined with sham stimulation. tDCS stimulation is performed over 3\u2009weeks of hospitalization, 20\u2009min/time, five times a week. Reward strategies refers to personalized active exercise programs for patients during hospitalization and at home. Patients can voluntarily choose tasks for active exercise and self-report to the therapist so as to punch a card for points and exchange gifts. The conventional group will receive home rehabilitation instructions prior to discharge. Rehabilitation motivation, measured using RMS. RMS, FMA, FIM, and ICF activity and social engagement scale will be compared at baseline, 3\u2009weeks, 6\u2009weeks, and 3\u2009months post-enrollment to evaluate patients' multifaceted health condition based on the ICF framework.\nDISCUSSION UNASSIGNED This study integrates knowledge from social cognitive science, economic behavioral science, and other relevant fields. We utilize straightforward and feasible reward strategies, combined with neuromodulation technology, to jointly improve patients' rehabilitation motivation. Behavioral observations and various assessment tools will be used to monitor patients' rehabilitation motivation and multifaceted health condition according to the ICF framework. The aim is to provide a preliminary exploration path for professionals to develop comprehensive strategies for improving patient rehabilitation motivation and facilitating a complete \"hospital-home-society\" rehabilitation process.\nCLINICAL TRIAL REGISTRATION UNASSIGNED https://www.chictr.org.cn/showproj.aspx?proj=182589, ChiCTR2300069068.",
      "authors": [
        "Zhou, Ping",
        "Li, Wenxi",
        "Zhao, Jingwang",
        "Chen, Siyun",
        "Chen, Yufeng",
        "Shen, Xia",
        "Xu, Dongsheng"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3389/fneur.2023.1200741",
      "keywords": [
        "N patient-centered care",
        "@UI",
        "N electric stimulation therapy",
        "N social cognition",
        "N stroke",
        "#text",
        "N rehabilitation medicine"
      ],
      "number_of_pages": null,
      "pages": "1200741",
      "publication": {
        "category": "Journal",
        "cite_score": 4.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1664-2295",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.978,
        "snip": 1.151,
        "subject_areas": [
          "Neurology (clinical)",
          "Neurology"
        ],
        "title": "Frontiers in neurology"
      },
      "publication_date": "2023-06-15",
      "selected": false,
      "title": "Modulated effectiveness of rehabilitation motivation by reward strategies combined with tDCS in stroke: study protocol for a randomized controlled trial.",
      "urls": []
    },
    {
      "abstract": "The Visual Word Form Area (VWFA) is a key region of the brain's reading network and its activation has been shown to be strongly associated with reading skills. Here, for the first time, we investigated whether voluntary regulation of VWFA activation is feasible using real-time fMRI neurofeedback. 40 adults with typical reading skills were instructed to either upregulate (UP group, N\u2009=\u200920) or downregulate (DOWN group, N\u2009=\u200920) their own VWFA activation during six neurofeedback training runs. The VWFA target region was individually defined based on a functional localizer task. Before and after training, also regulation runs without feedback (\"no-feedback runs\") were performed. When comparing the two groups, we found stronger activation across the reading network for the UP than the DOWN group. Further, activation in the VWFA was significantly stronger in the UP group than the DOWN group. Crucially, we observed a significant interaction of group and time (pre, post) for the no-feedback runs: The two groups did not differ significantly in their VWFA activation before neurofeedback training, but the UP group showed significantly stronger activation than the DOWN group after neurofeedback training. Our results indicate that upregulation of VWFA activation is feasible and that, once learned, successful upregulation can even be performed in the absence of feedback. These results are a crucial first step toward the development of a potential therapeutic support to improve reading skills in individuals with reading impairments.",
      "authors": [
        "Haugg, Amelie",
        "Frei, Nada",
        "Menghini, Milena",
        "Stutz, Felizia",
        "Steinegger, Sara",
        "R\u00f6thlisberger, Martina",
        "Brem, Silvia"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1038/s41598-023-35932-9",
      "keywords": [],
      "number_of_pages": null,
      "pages": "9195",
      "publication": {
        "category": "Journal",
        "cite_score": 7.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2045-2322",
        "publisher": "Nature Publishing Group",
        "sjr": 0.973,
        "snip": 1.312,
        "subject_areas": [
          "Multidisciplinary"
        ],
        "title": "Scientific reports"
      },
      "publication_date": "2023-06-06",
      "selected": false,
      "title": "Self-regulation of visual word form area activation with real-time fMRI neurofeedback.",
      "urls": []
    },
    {
      "abstract": "Dopamine system dysfunction is commonly implicated in adolescent-onset neuropsychiatric disorders. Although psychosis symptoms can be alleviated by antipsychotics, cognitive symptoms remain unresponsive to such pharmacological treatments and novel research paradigms investigating the circuit substrates underlying cognitive deficits are critically needed. The frontal cortex and its dopaminergic input from the midbrain are implicated in cognitive functions and undergo maturational changes during adolescence. Here, we used mice carrying mutations in the Arc or DISC1 genes to model mesofrontal dopamine circuit deficiencies and test circuit-based neurostimulation strategies to restore cognitive functions. We found that in a memory-guided spatial navigation task, frontal cortical neurons were activated coordinately at the decision-making point in wild-type but not Arc mutant mice. Chemogenetic stimulation of midbrain dopamine neurons or optogenetic stimulation of frontal cortical dopamine axons in a limited adolescent period consistently reversed genetic defects in mesofrontal innervation, task-coordinated neuronal activity, and memory-guided decision-making at adulthood. Furthermore, adolescent stimulation of dopamine neurons also reversed the mesofrontal circuit and cognitive deficits in DISC1 mutant mice. Our findings reveal common mesofrontal circuit alterations underlying the cognitive deficits caused by two different genes and demonstrate the feasibility of adolescent neurostimulation to reverse these circuit and behavioral deficits. These results may suggest developmental windows and circuit targets for treating cognitive deficits in neurodevelopmental disorders. \u00c2\u00a9 2023, eLife Sciences Publications Ltd. All rights reserved.",
      "authors": [
        "Mastwal, S.",
        "Li, X.",
        "Stowell, R.",
        "Manion, M.",
        "Zhang, W.",
        "Kim, N.-S.",
        "Yoon, K.-J.",
        "Song, H.",
        "Ming, G.-L.",
        "Wang, K.H."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.7554/eLife.87414.1",
      "keywords": [],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "eLife"
      },
      "publication_date": "2023-06-01",
      "selected": false,
      "title": "Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex function",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85165317937&origin=inward"
      ]
    },
    {
      "abstract": "In communication, much information is conveyed not explicitly but rather covertly, based on shared assumptions and common knowledge. For instance, when asked \u00e2\u0080\u009cDid you bring your cat to the vet?\u00e2\u0080\u009d a person could reply \u00e2\u0080\u009cIt got hurt jumping down the table\u00e2\u0080\u009d, thereby implicating that, indeed, the cat was brought to the vet. The assumption that getting hurt jumping down a table motivates a vet visit is tacitly attributed to the speaker by the listener, which implies Theory of Mind (ToM) processes. In the present study, we apply repetitive transcranial magnetic stimulation to the right temporo-parietal junction (rTPJ), a key brain region underlying ToM, with the aim to disrupt ToM processes necessary for language understanding. We then assess effects on the comprehension of indirect speech acts and their matched direct controls. In one set of conditions, the direct and indirect stimuli where not matched for speech act type, whereas, in the other, these were matched, therefore providing an unconfounded test case for in/directness. When indirect speech acts and direct controls were matched for speech act type (both statements), the indirect ones took longer to process both following sham and verum TMS. However, when the indirect and direct speech acts were not matched for communicative function (accept/decline offer vs. descriptive statement respectively), then a delay was detected for the indirect ones following sham TMS but, crucially, not following verum TMS. Additionally, TMS affected behavior in a ToM task. We therefore do not find evidence that the rTPJ is causally involved in comprehending of indirectness per se, but conclude that it could be involved instead in the processing of specific social communicative activity of rejecting of accepting offers, or to a combination of differing in/directness and communicative function. Our findings are consistent with the view that ToM processing in rTPJ is more important and/or more pronounced for offer acceptance/rejection than for descriptive answers. \u00c2\u00a9 2023",
      "authors": [
        "Boux, Isabella P",
        "Pulverm\u00fcller, Friedemann"
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1016/j.neuropsychologia.2023.108588",
      "keywords": [
        "N Transcranial magnetic stimulation",
        "D016428 Journal Article",
        "N Theory of mind",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Neuropragmatics",
        "N Indirect speech acts",
        "N Right temporo-parietal junction"
      ],
      "number_of_pages": null,
      "pages": "108588",
      "publication": {
        "category": "Journal",
        "cite_score": 5.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1873-3514",
        "publisher": "Elsevier Ltd.",
        "sjr": 0.995,
        "snip": 1.03,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Experimental and Cognitive Psychology",
          "Behavioral Neuroscience"
        ],
        "title": "Neuropsychologia"
      },
      "publication_date": "2023-05-25",
      "selected": false,
      "title": "Does the right temporo-parietal junction play a role in processing indirect speech acts? A transcranial magnetic stimulation study.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85165919091&origin=inward"
      ]
    },
    {
      "abstract": "INTRODUCTION UNASSIGNED Feedback-based therapies such as biofeedback have a benefit in patients with mental health disorders. While biofeedback is heavily researched in outpatient settings, it has been rarely investigated in psychosomatic inpatient settings. The implementation of an additional treatment option in inpatient settings holds special requirements. The aim of this pilot study is the evaluation of additional biofeedback treatment in an inpatient psychosomatic-psychotherapeutic unit to derive clinical implications and recommendations for the future implementation of biofeedback offers.\nMETHODS UNASSIGNED The evaluation of the implementation process was investigated using a convergent parallel mixed methods approach (following MMARS guidelines). Quantitative questionnaires measured patients' acceptance and satisfaction with biofeedback treatment after receiving 10 sessions in addition to treatment as usual. After 6 months during implementation, qualitative interviews were conducted with biofeedback practitioners, i.e., staff nurses, examining acceptance and feasibility. Data analysis was conducted using either descriptive statistics or Mayring's qualitative content analysis.\nRESULTS UNASSIGNED In total, 40 patients and 10 biofeedback practitioners were included. Quantitative questionnaires revealed high satisfaction and acceptance in patients regarding biofeedback treatment. Qualitative interviews showed high acceptance in biofeedback practitioners but revealed several challenges that were encountered during the implementation process, e.g., increased workload due to additional tasks, organizational and structural difficulties. However, biofeedback practitioners were enabled to expand their own competencies and take over a therapeutic part of the inpatient treatment.\nDISCUSSION UNASSIGNED Even though patient satisfaction and staff motivation are high, the implementation of biofeedback in an inpatient unit requires special actions to be taken. Not only should personnel resources be planned and available in advance of implementation but also be the workflow for biofeedback practitioners as easy and quality of biofeedback treatment as high as possible. Consequently, the implementation of a manualized biofeedback treatment should be considered. Nevertheless, more research needs to be done about suitable biofeedback protocols for this patient clientele.",
      "authors": [
        "Schmidt, Kira",
        "Barac-Dammeyer, Drazena",
        "Kowalski, Axel",
        "Teigelack, Per",
        "Pfeiffer, Corinna",
        "Robitzsch, Anita",
        "D\u00f6rrie, Nora",
        "Skoda, Eva-Maria",
        "B\u00e4uerle, Alexander",
        "Fink, Madeleine",
        "Teufel, Martin"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3389/fpsyt.2023.1140880",
      "keywords": [
        "@UI",
        "N implementation",
        "N neurofeedback",
        "N inpatient",
        "N biofeedback",
        "N mixed methods",
        "N psychosomatic",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "1140880",
      "publication": {
        "category": "Journal",
        "cite_score": 5.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1664-0640",
        "publisher": "Frontiers Media S.A.",
        "sjr": 1.222,
        "snip": 1.265,
        "subject_areas": [
          "Psychiatry and Mental Health"
        ],
        "title": "Frontiers in psychiatry"
      },
      "publication_date": "2023-05-24",
      "selected": false,
      "title": "Implementing biofeedback treatment in a psychosomatic-psychotherapeutic inpatient unit: a mixed methods evaluation of acceptance, satisfaction, and feasibility.",
      "urls": []
    },
    {
      "abstract": "Transactive Memory System (TMS) is a group theory that describes how\ncommunication can enable the combination of individual minds into a group.\nWhile this theory has been extensively studied in human-human groups, it has\nnot yet been formally applied to socially assistive robot design. We\ndemonstrate how the three-phase TMS group communication process-which involves\nencoding, storage, and retrieval-can be leveraged to improve decision making in\nsocially assistive robots with multiple stakeholders. By clearly defining how\nthe robot is gaining information, storing and updating its memory, and\nretrieving information from its memory, we believe that socially assistive\nrobots can make better decisions and provide more transparency behind their\nactions in the group context. Bringing communication theory to robot design can\nprovide a clear framework to help robots integrate better into human-human\ngroup dynamics and thus improve their acceptance and use.",
      "authors": [
        "Yaxin Hu",
        "Laura Stegner",
        "Bilge Mutlu"
      ],
      "categories": null,
      "citations": null,
      "comments": "Paper Accepted to Workshop \"Socially Assistive Robots as Decision\n  Makers: Transparency, Motivations, and Intentions\" (SARs: TMI - 2023) at CHI\n  2023",
      "databases": [
        "arXiv"
      ],
      "doi": null,
      "keywords": [],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Preprint",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [
          "Human-Computer Interaction",
          "Robotics"
        ],
        "title": "arXiv"
      },
      "publication_date": "2023-05-09",
      "selected": false,
      "title": "Knowing Who Knows What: Designing Socially Assistive Robots with Transactive Memory System",
      "urls": [
        "http://arxiv.org/abs/2305.05115v1",
        "http://arxiv.org/pdf/2305.05115v1"
      ]
    },
    {
      "abstract": "n n d' The role of the sensory visual cortex during visual short-term memory (VSTM) remains controversial. This controversy is possibly due to methodological issues in previous attempts to investigate the effects of transcranial magnetic stimulation (TMS) on VSTM. The aim of this study was to use TMS, while covering previous methodological deficits. Sixty-four young adults were recruited to participate in two experiments (Experiment 1:  = 36; Experiment 2:  = 28) using a VSTM orientation change-detection task under TMS. Monocular vision was ensured using red-blue goggles combined with red-blue stimuli. Double-pulse TMS was delivered at different times (Experiment 1: 0, 200 or 1000 ms; Experiment 2: 200, 1000 ms) during a 2 s maintenance phase, on one side of the occipital hemisphere. In Experiment 2, a sham TMS condition was introduced. Decreased detection sensitivity () in the ipsilateral occipital hemisphere to visual hemifield, and in the real TMS (compared with sham TMS) condition indicated inhibitory TMS effects, and thus, a causal involvement of the sensory visual cortex during early (200 ms) and late (1000 ms) maintenance in VSTM. These findings are aligned with sensory recruitment, which proposes that both perceptual and memory processes rely upon the same neural substrates in the sensory visual cortex. The methods used in this study were preregistered and had received in-principle acceptance on 6 June 2022 (Stage 1 protocol can be found in: https://doi.org/10.17605/OSF.IO/EMPDT).",
      "authors": [
        "Phylactou, Phivos",
        "Shimi, Andria",
        "Konstantinou, Nikos"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1098/rsos.230321",
      "keywords": [
        "N sensory recruitment",
        "@UI",
        "N sensory visual cortex",
        "N visual short-term memory",
        "N working memory",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "230321",
      "publication": {
        "category": "Journal",
        "cite_score": 6.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2054-5703",
        "publisher": "The Royal Society",
        "sjr": 0.841,
        "snip": 1.173,
        "subject_areas": [
          "Multidisciplinary"
        ],
        "title": "Royal Society open science"
      },
      "publication_date": "2023-04-19",
      "selected": false,
      "title": "Causal evidence for the role of the sensory visual cortex in visual short-term memory maintenance.",
      "urls": []
    },
    {
      "abstract": "OBJECTIVE Deep brain stimulation (DBS) and whether it alters patient personality is a much-debated topic within academic literature, yet rarely explored with those directly involved. This study qualitatively examined how DBS for treatment-resistant depression impacts patient personality, self-concept, and relationships from the perspectives of both patients and caregivers.\nMETHODS A prospective qualitative design was used. Eleven participants were included (six patients, five caregivers). Patients were enrolled in a clinical trial of DBS of the bed nucleus of the stria terminalis. Semi-structured interviews were conducted with participants before DBS-implantation and 9-months after stimulation-initiation. The 21 interviews were thematically analysed.\nRESULTS Three primary themes were identified: (a) impact of mental illness and treatment on self-concept; (b) device acceptability and usability, and (c) relationships and connection. Severe refractory depression had profoundly impacted who patients were, how they viewed themselves, and the quality and functioning of their relationships. Patients who benefited from DBS felt reconnected with their premorbid self, yet still far from their ideal self. While reductions in depression were broadly beneficial for relationships, the process of adjusting relationship dynamics created new challenges. All patients reported recharging difficulties and challenges adapting to the device.\nCONCLUSIONS Therapeutic response to DBS is a gradual and complex process that involves an evolving self-concept, adjusting relationship dynamics, and growing connection between body and device. This is the first study to provide in-depth insight into the lived experience of DBS for treatment-resistant depression. Patient and caregiver narrative accounts should be routinely collected to guide more person-centred DBS clinical interventions.",
      "authors": [
        "Thomson, Cassandra J",
        "Segrave, Rebecca A",
        "Fitzgerald, Paul B",
        "Richardson, Karyn E",
        "Racine, Eric",
        "Carter, Adrian"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1371/journal.pone.0284160",
      "keywords": [],
      "number_of_pages": null,
      "pages": "e0284160",
      "publication": {
        "category": "Journal",
        "cite_score": 6.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1932-6203",
        "publisher": "Public Library of Science",
        "sjr": 0.885,
        "snip": 1.253,
        "subject_areas": [
          "Multidisciplinary"
        ],
        "title": "PloS one"
      },
      "publication_date": "2023-04-06",
      "selected": false,
      "title": "Personal and relational changes following deep brain stimulation for treatment-resistant depression: A prospective qualitative study with patients and caregivers.",
      "urls": []
    },
    {
      "abstract": "Background: Transcranial direct current stimulation (tDCS) is a brain stimulation technique currently being researched as an alternative or complimentary treatment for various neurological disorders. There is little knowledge about experiences of the participants of tDCS clinical research, especially from pediatric studies. Methods: An interview study with typically developing minors (n = 19, mean age 13,66\u00c2 years) participating in a tDCS study, and their parents (n = 18) was conducted to explore their views and experiences and inform the ethical analysis. Results: Children (10\u00e2\u0080\u009313\u00c2 years old) and adolescents (14\u00e2\u0080\u009318\u00c2 years old) reported good experiences with the stimulation. Next to financial incentives, main motives to participate in the study were curiosity and the possibility to help develop treatments for children affected by neurological disorders. They could also see a potential of using tDCS in a non-medical setting, especially regarding the provision of equal opportunity, e.g. in education. Parents also presented a positive attitude towards tDCS and their children participation in the basic research study. Nevertheless, their understanding of tDCS was rather poor. Even though many of them understood the techniques, they often did not see the link between the (current) lack of side effects and an absence of longitudinal studies. Parents were also cautious about using tDCS for non-medical/enhancement purposes. Conclusions: The study findings show a need for more transparent information about the state of the art of tDCS, its function and what it might be able to offer, especially considering the good acceptability of tDCS. \u00c2\u00a9 2022, The Author(s).",
      "authors": [
        "Sierawska, A.",
        "Splittgerber, M.",
        "Moliadze, V.",
        "Siniatchkin, M.",
        "Buyx, A."
      ],
      "categories": null,
      "citations": 1,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1007/s12152-022-09507-w",
      "keywords": [
        "Research ethics",
        "Pediatric research",
        "tDCS",
        "Neuroethics"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 3.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "18745490",
        "publisher": "Springer Netherlands",
        "sjr": 0.339,
        "snip": 0.676,
        "subject_areas": [
          "Psychiatry and Mental Health",
          "Neurology",
          "Issues, Ethics and Legal Aspects",
          "Health Policy",
          "Philosophy"
        ],
        "title": "Neuroethics"
      },
      "publication_date": "2023-04-01",
      "selected": false,
      "title": "Transcranial Direct Current Stimulation (tDCS) in Pediatric Populations\u2014\u2013 Voices from Typically Developing Children and Adolescents and their Parents",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85141187482&origin=inward"
      ]
    },
    {
      "abstract": "Coupling a high-performance core to a low heat flux divertor is a crucial step for ITER and a Fusion Pilot Plant or DEMO. Experiments in DIII-D recently expanded the steady-state hybrid scenario to high density and divertor impurity injection to study the feasibility of a radiating mantle solution. This work presents the physics basis for trade-offs between density, current drive and stability to tearing modes (TMs) at high \u00ce\u00b2. EC power is crucial to tailor the plasma profiles into a passively stable state, and to eject impurities from the core. Off-axis EC depositions decrease the heating efficiency, but calculated electron heat transport coefficients show that this effect is partially mitigated by improved confinement inside the EC deposition. Additionally, the reduction in pressure is recovered by increasing the density. This favourable scaling of confinement with density was observed in high power plasmas for years, and this work provides a comprehensive explanation. ELITE predictions indicate that a path in peeling-ballooning stability opens up for certain conditions of density, power, q 95 and shaping, allowing the edge pressure to continue increasing without encountering a limit. In the core, calculated anomalous fast-ion diffusion coefficients are consistent with density fluctuation measurements in the toroidicity-induced Alfv\u00c3\u00a9n eigenmode range, showing that smaller fast-ion losses contribute to the enhanced confinement at high density. The edge integration study shows that divertor heat loads can be reduced with Ne and Ar injection, but this eventually triggers a cascade of n = 1, 2, 3 core TMs. We can now show that impurity radiation in the core is small and it is not the cause for the drop in confinement at high Ar and Ne injection rates. The overlap between the core TMs is consistent with the loss of pressure as estimated by the Belt model for the coupled rational surfaces. Optimization of these trade-offs has achieved plasmas with sustained H 98y2 = 1.7, f GW = 0.7 and \u00e2\u0088\u00bc85% mantle radiation. The scenario and its variations at higher density and on- vs off-axis EC heating has been studied as a candidate for an integrated solution for several reactor designs, such as ITER, ARC, and the ARIES-ACT1 case, showing promising results in terms of fusion power and gain. \u00c2\u00a9 2023 The Author(s). Published on behalf of IAEA by IOP Publishing Ltd.",
      "authors": [
        "Turco, F.",
        "Petrie, T.",
        "Osborne, T.",
        "Petty, C.C.",
        "Luce, T.C.",
        "Grierson, B.",
        "Odstrcil, T.",
        "Van Zeeland, M.A.",
        "Liu, D.",
        "Casali, L.",
        "Boyes, W.",
        "Smith, S.P.",
        "Shen, H.",
        "Kostuk, M.",
        "Brennan, D."
      ],
      "categories": null,
      "citations": 1,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1088/1741-4326/acb370",
      "keywords": [
        "core-edge integration",
        "hybrid scenario",
        "high-performance",
        "steady-state",
        "FPP"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 6.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "00295515",
        "publisher": "IOP Publishing Ltd.",
        "sjr": 1.447,
        "snip": 1.462,
        "subject_areas": [
          "Condensed Matter Physics",
          "Nuclear and High Energy Physics"
        ],
        "title": "Nuclear Fusion"
      },
      "publication_date": "2023-03-01",
      "selected": false,
      "title": "The physics basis to integrate an MHD stable, high-power hybrid scenario to a cool divertor for steady-state reactor operation",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85147989087&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND Dementia [i.e., Alzheimer disease (AD)], the most common neurodegenerative disease, causes profound negative impacts on executive function and quality of life. Available pharmacological treatments often fail to achieve satisfactory outcomes. Noninvasive brain stimulation (NIBS) techniques, which focally modify cortical function and enhance synaptic long-term potentiation, are potentially beneficial for the cognition in patients with AD. The aim of the current network meta-analysis (NMA) was to evaluate the efficacy and safety of different NIBS interventions in patients with AD through NMA.\nMETHODS Only randomized controlled trials (RCTs) examining NIBS interventions in patients with AD had been included. All NMA procedures were performed under the frequentist model. The primary and secondary outcomes were changes in cognitive function and quality of life, respectively.\nRESULTS Nineteen RCTs (639 participants) were included. The mean treatment and follow-up durations were 5.7 and 10.5 weeks, respectively. The combination of cathodal tDCS of the left dorsolateral prefrontal cortex and anodal tDCS over the right supraorbital region (c-tDCS-F3 + a-tDCS-Fp2) was associated with a significant beneficial effect on cognition compared with sham controls (standardized mean difference=2.43, 95% confidence interval=0.61-4.26, n=12 and 11). It was also associated with the greatest beneficial effect on cognition among all the investigated NIBS approaches. All the methods were well tolerated with regard to the safety profile, as reflected in the rates of adverse events or local discomfort, as well as acceptability, as indicated by dropout rate.\nCONCLUSIONS The present findings provide evidence of the benefits of NIBS, especially tDCS, for beneficial effect on cognition in patients with AD. However, because of few studies included, this effect was not replicated yet in the other studies. Therefore, future larger-scale and longer follow-up duration RCTs should be warranted.\nTRIAL REGISTRATION PROSPERO CRD42020209516. The current study had been approved by the Institutional Review Board of the Tri-Service General Hospital, National Defense Medical Center (TSGHIRB No. B-109-29).",
      "authors": [
        "Tseng, Ping-Tao",
        "Chen, Yen-Wen",
        "Zeng, Bing-Yan",
        "Zeng, Bing-Syuan",
        "Hung, Chao-Ming",
        "Sun, Cheuk-Kwan",
        "Cheng, Yu-Shian",
        "Stubbs, Brendon",
        "Carvalho, Andre F",
        "Brunoni, Andre R",
        "Su, Kuan-Pin",
        "Tu, Yu-Kang",
        "Wu, Yi-Cheng",
        "Chen, Tien-Yu",
        "Lin, Pao-Yen",
        "Liang, Chih-Sung",
        "Hsu, Chih-Wei",
        "Chu, Che-Sheng",
        "Suen, Mein-Woei",
        "Li, Cheng-Ta"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1186/s13195-023-01164-2",
      "keywords": [
        "N Cognition",
        "N Dementia",
        "D016428 Journal Article",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Primary care",
        "N Alzheimer\u2019s disease",
        "D017418 Meta-Analysis",
        "N Neuropathology"
      ],
      "number_of_pages": null,
      "pages": "20",
      "publication": {
        "category": "Journal",
        "cite_score": 12.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1758-9193",
        "publisher": "BioMed Central Ltd.",
        "sjr": 2.65,
        "snip": 1.849,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Neurology (clinical)",
          "Neurology"
        ],
        "title": "Alzheimer's research & therapy"
      },
      "publication_date": "2023-01-25",
      "selected": false,
      "title": "The beneficial effect on cognition of noninvasive brain stimulation intervention in patients with dementia: a network meta-analysis of randomized controlled trials.",
      "urls": []
    },
    {
      "abstract": "The goal of this study was to examine social feedback processing among emerging adults with borderline personality features (BPF). Participants (N = 118; 66.9% female) completed ratings of BPF and a computerized peer interaction task designed to measure processing of rejection and acceptance cues at the neurophysiological (i.e., electroencephalogram [EEG]), behavioral, and self-report levels. When covarying symptoms of depression and social anxiety, greater BPF were associated with heightened neural processing of social acceptance cues, accounting for reactivity to neutral and rejection cues, as demonstrated by an enhanced reward positivity (RewP) component. Additionally, BPF were associated with less adaptive voting in response to peer acceptance, such that emerging adults with higher BPF made fewer votes to keep peers in the game who had provided acceptance feedback to participants. These neural and behavioral patterns associated with BPF highlight the potential role of social reward processing in borderline personality. Specifically, emerging adults high in BPF show a hyper-responsiveness to social acceptance at the neural level but difficulty modulating behavioral responses in an adaptive way to obtain more social rewards. Future research replicating these effects across development may guide efforts to address and prevent the profound social dysfunction associated with BPF. \u00c2\u00a9 2022 Elsevier Inc.",
      "authors": [
        "Babinski, D.E.",
        "Pegg, S.",
        "West, M.",
        "Arfer, K.B.",
        "Kujawa, A."
      ],
      "categories": null,
      "citations": 2,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1016/j.pnpbp.2022.110648",
      "keywords": [
        "Social reward",
        "Event-related potentials",
        "Social processing",
        "Borderline personality",
        "Electroencephalogram"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 10.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "02785846",
        "publisher": "Elsevier Inc.",
        "sjr": 1.543,
        "snip": 1.314,
        "subject_areas": [
          "Pharmacology",
          "Biological Psychiatry"
        ],
        "title": "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
      },
      "publication_date": "2023-01-10",
      "selected": false,
      "title": "Borderline personality features and altered social feedback processing in emerging adults: An EEG study",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85139287811&origin=inward"
      ]
    },
    {
      "abstract": "Prior studies show that neurofeedback training (NFT) of mu rhythms improves behavior and EEG mu rhythm suppression during action observation in children with autism spectrum disorder (ASD). However, intellectually impaired persons were excluded because of their behavioral challenges. We aimed to determine if intellectually impaired children with ASD, who were behaviorally prepared to take part in a mu-NFT study using conditioned auditory reinforcers, would show improvements in symptoms and mu suppression following mu-NFT. Seven children with ASD (ages 6\u00e2\u0080\u00938; mean IQ 70.6 \u00c2\u00b1 7.5) successfully took part in mu-NFT. Four cases demonstrated positive learning trends (hit rates) during mu-NFT (learners), and three cases did not (non-learners). Artifact-creating behaviors were present during tests of mu suppression for all cases, but were more frequent in non-learners. Following NFT, learners showed behavioral improvements and were more likely to show evidence of a short-term increase in mu suppression relative to non-learners who showed little to no EEG or behavior improvements. Results support mu-NFT\u00e2\u0080\u0099s application in some children who otherwise may not have been able to take part without enhanced behavioral preparations. Children who have more limitations in demonstrating learning during NFT, or in providing data with relatively low artifact during task-dependent EEG tests, may have less chance of benefiting from mu-NFT. Improving the identification of ideal mu-NFT candidates, mu-NFT learning rates, source analyses, EEG outcome task performance, population-specific artifact-rejection methods, and the theoretical bases of NFT protocols, could aid future BCI-based, neurorehabilitation efforts. \u00c2\u00a9 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",
      "authors": [
        "LaMarca, Kristen",
        "Gevirtz, R",
        "Lincoln, Alan J",
        "Pineda, Jaime A"
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1007/s10484-022-09576-w",
      "keywords": [
        "N Mu rhythms",
        "N Mirror neurons",
        "#text",
        "N Neurofeedback",
        "N Autism",
        "N Intellectual disability",
        "N Brain\u2013computer interface",
        "@UI"
      ],
      "number_of_pages": 17,
      "pages": "229-245",
      "publication": {
        "category": "Journal",
        "cite_score": 5.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1573-3270",
        "publisher": "Springer New York",
        "sjr": 0.534,
        "snip": 1.182,
        "subject_areas": [
          "Applied Psychology",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Applied psychophysiology and biofeedback"
      },
      "publication_date": "2023-01-06",
      "selected": false,
      "title": "Brain-Computer Interface Training of mu EEG Rhythms in Intellectually Impaired Children with Autism: A Feasibility Case Series.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85145838310&origin=inward"
      ]
    },
    {
      "abstract": "n n p p Although transcranial direct current stimulation (tDCS) is emerging as a convenient pain relief modality for several chronic pain conditions, its feasibility, acceptability, and preliminary efficacy on pain in patients with Alzheimer's disease and related dementias (ADRD) have not been investigated. The purpose of this pilot study was to assess the feasibility, acceptability, and preliminary efficacy of 5, 20-min home-based tDCS sessions on chronic pain in older adults with ADRD. We randomly assigned 40 participants to active ( = 20) or sham ( = 20) tDCS. Clinical pain intensity was assessed using a numeric rating scale (NRS) with patients and a proxy measure (MOBID-2) with caregivers. We observed significant reductions of pain intensity for patients in the active tDCS group as reflected by both pain measures (NRS: Cohen's d = 0.69, -value = 0.02); MOBID-2: Cohen's d = 1.12, -value = 0.001). Moreover, we found home-based tDCS was feasible and acceptable intervention approach for pain in ADRD. These findings suggest the need for large-scale randomized controlled studies with larger samples and extended versions of tDCS to relieve chronic pain on the long-term for individuals with ADRD.",
      "authors": [
        "Martorella, Geraldine",
        "Miao, Hongyu",
        "Wang, Duo",
        "Park, Lindsey",
        "Mathis, Kenneth",
        "Park, JuYoung",
        "Sheffler, Julia",
        "Granville, Lisa",
        "Teixeira, Antonio L",
        "Schulz, Paul E",
        "Ahn, Hyochol"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3390/jcm12020401",
      "keywords": [
        "N feasibility",
        "@UI",
        "N efficacy",
        "N Alzheimer\u2019s disease and related dementias",
        "N acceptability",
        "N pain",
        "N transcranial direct current stimulation",
        "#text"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 5.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2077-0383",
        "publisher": "MDPI AG",
        "sjr": 0.935,
        "snip": 1.179,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "Journal of clinical medicine"
      },
      "publication_date": "2023-01-04",
      "selected": false,
      "title": "Feasibility, Acceptability, and Efficacy of Home-Based Transcranial Direct Current Stimulation on Pain in Older Adults with Alzheimer's Disease and Related Dementias: A Randomized Sham-Controlled Pilot Clinical Trial.",
      "urls": []
    },
    {
      "abstract": "Differentiating healthy from pathological aging trajectories is extremely timely, as the global population faces an inversion where older adults will soon outnumber younger 5:1. Many cognitive functions (e.g., memory, executive functions, and processing speed) decline with age, a process that can begin as early as midlife, and which predicts subsequent diagnosis with dementia. Although dementia is a devastating and costly diagnosis, there remains limited evidence for medications, therapies, and devices that improve cognition or attenuate the transition into dementia. There is an urgent need to intervene early in neurodegenerative processes leading to dementia (e.g., depression and mild cognitive impairment). In this targeted review and commentary, we highlight transcutaneous Vagus Nerve Stimulation (tVNS) as a neurostimulation method with unique opportunities for applications in diseases of aging, reviewing recent literature, feasibility of use with remote data collection methods/telehealth, as well as limitations and conflicts in the literature. In particular, small sample sizes, uneven age distributions of participants, lack of standardized protocols, and oversampling of non-representative groups (e.g., older adults with no comorbid diagnoses) limit our understanding of the potential of this method. We offer recommendations for how to improve representativeness, statistical power, and generalizability of tVNS research by integrating remote data collection techniques. Copyright \u00c2\u00a9 2023 Naparstek, Yeh and Mills-Finnerty.",
      "authors": [
        "Naparstek, S.",
        "Yeh, A.K.",
        "Mills-Finnerty, C."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3389/fnagi.2023.1145207",
      "keywords": [
        "cognition",
        "dementia",
        "healthy aging",
        "transcutaneous Vagus Nerve Stimulation (tVNS)",
        "remote data collection"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Frontiers in Aging Neuroscience"
      },
      "publication_date": "2023-01-01",
      "selected": false,
      "title": "Transcutaneous Vagus Nerve Stimulation (tVNS) applications in cognitive aging: a review and commentary",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85165591783&origin=inward"
      ]
    },
    {
      "abstract": "Individuals with a diagnosis of schizophrenia face a myriad of obstacles to wellness, beginning with diagnostic discrepancies including over- and misdiagnoses on the schizophrenia spectrum. People with schizophrenia experience profound amounts of stigmatization from the general population, their healthcare providers, and even themselves. Such stigmatization creates a barrier for wellness, poorer prognoses, and often limits adherence to physical and mental healthcare. Moreover, it can exacerbate the already stifling symptomatology of their diagnoses, including specific bodily-related symptomatology. Oftentimes, a diagnosis of schizophrenia disrupts one\u00e2\u0080\u0099s relationship with their body including a diminished mind-body connection, decreased interoceptive awareness, and thus unsuccessful intra- and interpersonal relationships. Some recent research suggests the use of mind-body therapies, however, if these practices are internalizing, they may not be appropriate for people with schizophrenia experiencing more acute symptomatology excluding them from treatment. Dance/movement therapy (DMT) is an embodied psychotherapeutic treatment option that can support participants in improving mind-body connection, social relationships, and self-regulatory skill development. Research on DMT has shown promising results for people with schizophrenia, however such research is limited and would benefit from increased studies that particularly measure the effects of DMT on mind-body connection and increased interoception for people with schizophrenia. Moreover, integrative and collaborative treatment models that couple DMT and biofeedback may further our understanding of the physiological and neurological effects of DMT interventions for people with schizophrenia and beyond. This review will examine the recent literature on health inequities for people with schizophrenia, their specific body-based disruptions and needs, and DMT as a promising treatment model, particularly when coupled with biofeedback. Copyright: \u00c2\u00a9 2023 Biondo J.",
      "authors": [
        "Biondo, J."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.12688/f1000research.127377.2",
      "keywords": [
        "interoception",
        "neurobiology",
        "mind-body connection",
        "embodiment",
        "schizophrenia",
        "dance/movement therapy",
        "healthcare disparities"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "F1000Research"
      },
      "publication_date": "2023-01-01",
      "selected": false,
      "title": "Dance/movement therapy as a holistic approach to diminish health discrepancies and promote wellness for people with schizophrenia: a review of the literature",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85168268597&origin=inward"
      ]
    },
    {
      "abstract": "Objective. Brain-computer interfaces (BCIs) are emerging as promising cognitive training tools in neurodevelopmental disorders, as they combine the advantages of traditional computerized interventions with real-time tailored feedback. We propose a gamified BCI based on non-volitional neurofeedback for cognitive training, aiming at reaching a neurorehabilitation tool for application in autism spectrum disorders (ASDs). Approach. The BCI consists of an emotional facial expression paradigm controlled by an intelligent agent that makes correct and wrong actions, while the user observes and judges the agent\u00e2\u0080\u0099s actions. The agent learns through reinforcement learning (RL) an optimal strategy if the participant generates error-related potentials (ErrPs) upon incorrect agent actions. We hypothesize that this training approach will allow not only the agent to learn but also the BCI user, by participating through implicit error scrutiny in the process of learning through operant conditioning, making it of particular interest for disorders where error monitoring processes are altered/compromised such as in ASD. In this paper, the main goal is to validate the whole methodological BCI approach and assess whether it is feasible enough to move on to clinical experiments. A control group of ten neurotypical participants and one participant with ASD tested the proposed BCI approach. Main results. We achieved an online balanced-accuracy in ErrPs detection of 81.6% and 77.1%, respectively for two different game modes. Additionally, all participants achieved an optimal RL strategy for the agent at least in one of the test sessions. Significance. The ErrP classification results and the possibility of successfully achieving an optimal learning strategy, show the feasibility of the proposed methodology, which allows to move towards clinical experimentation with ASD participants to assess the effectiveness of the approach as hypothesized. \u00c2\u00a9 2022 The Author(s). Published by IOP Publishing Ltd.",
      "authors": [
        "Pires, Gabriel",
        "Cruz, Aniana",
        "Jesus, Diogo",
        "Yasemin, Mine",
        "Nunes, Urbano J",
        "Sousa, Teresa",
        "Castelo-Branco, Miguel"
      ],
      "categories": null,
      "citations": 2,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1088/1741-2552/aca798",
      "keywords": [
        "N observation error-related potential (ErrP)",
        "N autism spectrum disorders",
        "N brain\u2013computer interface",
        "D016428 Journal Article",
        "D013485 Research Support, Non-U.S. Gov't",
        "N reinforcement learning"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1741-2552",
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Journal of neural engineering"
      },
      "publication_date": "2022-12-12",
      "selected": false,
      "title": "A new error-monitoring brain-computer interface based on reinforcement learning for people with autism spectrum disorders.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85144294059&origin=inward"
      ]
    },
    {
      "abstract": "Purpose of reviewThis review examines recent evidence that informs the treatment of anxiety-related disorders.Recent findingsIn addition to selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), and benzodiazepines, agomelatine has demonstrated efficacy in treating generalized anxiety disorder (GAD). Other novel products, such as ketamine, psilocybin and cannabidiol, are in the process of gathering evidence in support of the treatment of anxiety disorders. In psychological therapy, various psychological treatments for anxiety disorders, such as mindfulness-based intervention, acceptance and commitment therapy, psychodynamic therapy, emotion-focused therapy and dialectical behavioural therapy, have been tried. Still, most therapies have not proven superior to cognitive behavioural therapy (CBT). In very preliminary findings: Repetitive transcranial magnetic stimulation (rTMS) was effective in GAD; transcranial direct current stimulation (tDCS) was effective for social anxiety disorder (SAD) and GAD and augmented exposure therapy for specific fears. Internet and mobile-based interventions have comparable efficacy to face-to-face therapy.SummaryPharmacotherapy of anxiety disorders is expanding to novel products. Despite trying other psychological therapies for anxiety disorders, most therapies were comparable to but not superior to CBT. rTMS and tDCS were also used and show early promise for GAD, but further studies are needed. Most internet or mobile app based psychological therapies were based on CBT, and some can be considered as alternatives to in-person face-to-face therapy. \u00c2\u00a9 2023 Lippincott Williams and Wilkins. All rights reserved.",
      "authors": [
        "Lee, Hyun Jeong",
        "Stein, Murray B"
      ],
      "categories": null,
      "citations": 6,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1097/YCO.0000000000000841",
      "keywords": [
        "pharmacotherapy",
        "technology-delivered therapy",
        "psychological therapy",
        "anxiety disorder"
      ],
      "number_of_pages": 6,
      "pages": "140-145",
      "publication": {
        "category": "Journal",
        "cite_score": 9.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1473-6578",
        "publisher": "Lippincott Williams and Wilkins Ltd.",
        "sjr": 1.82,
        "snip": 1.788,
        "subject_areas": [
          "Psychiatry and Mental Health"
        ],
        "title": "Current opinion in psychiatry"
      },
      "publication_date": "2022-12-06",
      "selected": false,
      "title": "Update on treatments for anxiety-related disorders.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85147047196&origin=inward"
      ]
    },
    {
      "abstract": "Neurofeedback training is an established treatment for children with attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder and is an increasingly accepted modality of treatment in the context of child trauma. This treatment is typically delivered as a complement to more traditional talk therapy such as trauma-focused-cognitive behavioral therapy (TF-CBT). This review examined the evidence for the effectiveness of this intervention for children with trauma through a systematic search of the literature. A targeted search across databases identified 10 eligible studies that focused on children/young people who had experienced traumatic events and/or demonstrated symptoms of trauma, and which conducted a repeated measures study at a minimum. While the included studies suggest some benefits from neurofeedback training, the available studies, including randomized trials, have to date been relatively small, involve dramatically different treatment length and intensity, and show inconsistent benefits relative to usual treatment conditions. To advance knowledge of this intervention further research is needed with a clear best practice protocol and with a clearer target group.",
      "authors": [
        "Schutz, Chantelle Alysse",
        "Herbert, James"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1177/15248380221134295",
      "keywords": [
        "D016428 Journal Article",
        "N PTSD",
        "N child trauma",
        "D016454 Review",
        "N neurofeedback",
        "N NFT"
      ],
      "number_of_pages": 15,
      "pages": "3564-3578",
      "publication": {
        "category": "Journal",
        "cite_score": 14.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1552-8324",
        "publisher": "SAGE Publications Ltd",
        "sjr": 2.422,
        "snip": 4.685,
        "subject_areas": [
          "Applied Psychology",
          "Public Health, Environmental and Occupational Health",
          "Health (social science)"
        ],
        "title": "Trauma, violence & abuse"
      },
      "publication_date": "2022-11-23",
      "selected": false,
      "title": "Review of the Evidence for Neurofeedback Training for Children and Adolescents Who Have Experienced Traumatic Events.",
      "urls": []
    },
    {
      "abstract": "BACKGROUND UNASSIGNED Postural instability is a prevalent issue among individuals with autism spectrum disorder (ASD) that affects the development of their perceptual-motor skills and social functioning. Visual and somatosensory processing deficits, hypotonia, basal ganglia dysfunction, and anxiety are some of the concurrent disorders in individuals with ASD. Nevertheless, a definite management protocol for postural instability in ASD has not been introduced yet. Hence, we aim to shed light on the available intervention strategies for postural instability in individuals with ASD.\nMETHODS UNASSIGNED Even though several studies have been conducted on the effects of various interventions for balance control in individuals with ASD, no study has compared their efficacy, limitations, and clinical implications.\nRESULTS UNASSIGNED This review discusses diverse proposed interventions contributing to ASD postural instability, including martial arts, water-based interventions, animal-assisted therapies, trampoline, balance training, vestibular therapy, transcranial direct current stimulation, sports, play, and active recreation for kids (SPARK), and square-stepping exercise (SSE).\nCONCLUSION UNASSIGNED Enhancing motor skills, cerebellum function, and sensory input integration were some of the main mechanisms of these interventions to improve balance control in ASD. Some interventions, such as water-based exercises and video games, were enjoyable for children with ASD and could raise their treatment adherence. In most studies, small sample sizes and the lack of a control group represented their major limitations. Therefore, future well-designed randomized controlled trials are required to assess the effects of available interventions on postural control in ASD.",
      "authors": [
        "Hariri, Rabeeh",
        "Nakhostin-Ansari, Amin",
        "Mohammadi, Fatemeh",
        "Memari, Amir Hossein",
        "Oskouie, Iman Menbari",
        "Haghparast, Afarin"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1155/2022/3639352",
      "keywords": [],
      "number_of_pages": null,
      "pages": "3639352",
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2090-1925",
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Autism research and treatment"
      },
      "publication_date": "2022-11-21",
      "selected": false,
      "title": "An Overview of the Available Intervention Strategies for Postural Balance Control in Individuals with Autism Spectrum Disorder.",
      "urls": []
    },
    {
      "abstract": "Language describes approach/avoidance intentionality by means of attitudinal verbs (e.g., accept vs. reject). The right superior temporal sulcus (rSTS) has been shown to be recruited in processing action goals and approach intentionality in social contexts. In this study, we examine whether transcranial direct current stimulation (tDCS) of this area improves the processing of attitudinal verbs (either of approach or avoidance) in the context of affirmative and negative sentences [e.g., Julio (did not)/included meat on the grocery list]. After being subjected to tDCS, 46 participants were given sentences for passive reading. Sentences were displayed in segments with a fixed time of exposition, and a verb, either the one mentioned in the sentence or an alternative one was displayed 1,500 ms after the sentence (e.g., included vs. excluded, in the example). Participants were told to read them and then press the space bar to continue the experiment. Results showed shorter latencies for approach verbs that were either mentioned in approach sentences or the alternatives in avoidance sentences, both in affirmative and negative versions under anodal conditions compared to sham conditions. Thus, the anodal stimulation of rSTS affected the accessibility of approach verbs that were not modulated either by being mentioned or by sentence polarity. In addition, mentioned verbs had shorter reading times than the alternative ones in negative sentences in the anodal vs. sham condition. This suggests that stimulation caused an effect of negation in the activation of the mentioned verb. Implications are discussed in the context of the role of the rSTS in processing attitudinal verbs and negation to understand better approach and avoidance mediated by language in the framework of the two-step model of negation processing.",
      "authors": [
        "Nuez, Aar\u00f3n",
        "Padr\u00f3n, Iv\u00e1n",
        "Reyes-Moreno, Cristian",
        "Marrero, Hip\u00f3lito"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3389/fnhum.2022.971051",
      "keywords": [
        "N approach/avoidance intentionality",
        "@UI",
        "N tDCS",
        "N negation",
        "N superior temporal sulcus",
        "N attitudes",
        "N reading",
        "N action understanding",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "971051",
      "publication": {
        "category": "Journal",
        "cite_score": 4.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1662-5161",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.787,
        "snip": 1.033,
        "subject_areas": [
          "Psychiatry and Mental Health",
          "Neurology",
          "Biological Psychiatry",
          "Neuropsychology and Physiological Psychology",
          "Behavioral Neuroscience"
        ],
        "title": "Frontiers in human neuroscience"
      },
      "publication_date": "2022-11-10",
      "selected": false,
      "title": "Effect of transcranialdirect current stimulation on the right brain temporal area on processing approach and avoidance attitudes with negation.",
      "urls": []
    },
    {
      "abstract": "INTRODUCTION Repetitive Transcranial Magnetic Stimulation (rTMS) has shown promising results in treating several Substance Use Disorders including Tobacco Use Disorder. However, questions remain regarding how to optimize treatment outcomes. Enhancement of working memory by rTMS is a potential therapeutic mechanism. The current pilot study examined whether rTMS plus a cognitive training program could enhance the effects of rTMS on smoking behaviors using a controlled, factorial design.\nAIMS AND METHODS We hypothesized that cognitive training plus stimulation would improve control over smoking behaviors, resulting in enhanced cognitive performance and increased latency to smoke on a delay to smoking analog task. Using a 2 \u00d7 2 factorial design, nicotine dependent smokers (n = 43) were randomized to receive 10 sessions of active (10 Hz) or sham rTMS delivered to the left dorsolateral prefrontal cortex, plus active or sham working memory training (WMT) prior to and following stimulation.\nRESULTS Contrary to hypotheses, we observed a significant interaction effect, indicating that combining the two active interventions (rTMS+WMT) resulted in worse performance on the smoking analog task (B = -33.0, 95% CI = -64.39, -1.61, p < .05), compared to delivering either intervention alone. Additionally, although active rTMS (compared to sham rTMS) improved letter-sequencing performance (B = 1.23, 95% CI = 0.08-2.38, p < .05), and active WMT (compared to sham WMT) improved back-digit task performance (B = 1.53, 95% CI = 0.02-3.05, p < .05), combining interventions worsened the effect of each on a back-digit task (B = -3.01, 95% CI = -5.96, -0.052, p < .05).\nCONCLUSIONS These preliminary findings indicate potential iatrogenic effects of combining rTMS and this working memory training intervention and underscore the need for rigorous evaluation of substance specific conceptual frameworks when selecting future combination interventions.\nIMPLICATIONS Counter to hypothesis, this study found no additional benefit of adding a working memory training program to a rTMS protocol in a sample of daily smokers. The combination condition (active rTMS + active training) resulted in worse performance on a delay to smoking analog task and a measure of working memory performance compared to delivering either intervention alone. These preliminary findings inform strategies for optimizing rTMS in smokers and highlight the need for future studies to consider several key components of candidate combination interventions, including effects on regulation of substance use.\nCLINICAL TRIAL REGISTRATION (IF ANY) The trial was registered at ClinicalTrials.gov (NCT03337113).",
      "authors": [
        "Lechner, William V",
        "Philip, Noah S",
        "Kahler, Christopher W",
        "Houben, Katrijn",
        "Tirrell, Eric",
        "Carpenter, Linda L"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1093/ntr/ntac183",
      "keywords": [],
      "number_of_pages": 10,
      "pages": "1871-1880",
      "publication": {
        "category": "Journal",
        "cite_score": 8.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1469-994X",
        "publisher": "Oxford University Press",
        "sjr": 1.512,
        "snip": 1.421,
        "subject_areas": [
          "Public Health, Environmental and Occupational Health"
        ],
        "title": "Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco"
      },
      "publication_date": "2022-11-01",
      "selected": false,
      "title": "Combined Working Memory Training and Transcranial Magnetic Stimulation Demonstrates Low Feasibility and Potentially Worse Outcomes on Delay to Smoking and Cognitive Tasks: A Randomized 2 \u00d7 2 Factorial Design Pilot and Feasibility Study.",
      "urls": []
    },
    {
      "abstract": "Enhanced behavioral interventions are gaining increasing interest as innovative treatment strategies for major depressive disorder (MDD). In this study protocol, we propose to examine the synergistic effects of a self-administered home-treatment, encompassing transcranial direct current stimulation (tDCS) along with a video game based training of attentional control. The study is designed as a two-arm, double-blind, randomized and placebo-controlled multi-center trial (ClinicalTrials.gov: NCT04953208). At three study sites (Israel, Latvia, and Germany), 114 patients with a primary diagnosis of MDD undergo 6 weeks of intervention (30 \u00c3\u0097 30\u00c2 min sessions). Patients assigned to the intervention group receive active tDCS (anode F3 and cathode F4; 2\u00c2 mA intensity) and an action-like video game, while those assigned to the control group receive sham tDCS along with a control video game. An electrode-positioning algorithm is used to standardize tDCS electrode positioning. Participants perform their designated treatment at the clinical center (sessions 1\u00e2\u0080\u00935) and continue treatment at home under remote supervision (sessions 6\u00e2\u0080\u009330). The endpoints are feasibility (primary) and safety, treatment efficacy (secondary, i.e., change of Montgomery-\u00c3\u0085sberg Depression Rating Scale (MADRS) scores at week six from baseline, clinical response and remission, measures of social, occupational, and psychological functioning, quality of life, and cognitive control (tertiary). Demonstrating the feasibility, safety, and efficacy of this novel combined intervention could expand the range of available treatments for MDD to neuromodulation enhanced interventions providing cost-effective, easily accessible, and low-risk treatment options. ClinicalTrials.gov: NCT04953208. \u00c2\u00a9 2022, The Author(s).",
      "authors": [
        "Dechantsreiter, Esther",
        "Padberg, Frank",
        "Morash, Alon",
        "Kumpf, Ulrike",
        "Nguyen, Arthur",
        "Menestrina, Zeno",
        "Windel, Fabienne",
        "Burkhardt, Gerrit",
        "Goerigk, Stephan",
        "Morishita, Takuya",
        "Soldini, Aldo",
        "Ahissar, Shira",
        "Cohen, Tamar",
        "Pasqualotto, Angela",
        "Rubene, Linda",
        "Konosonoka, Liene",
        "Keeser, Daniel",
        "Zill, Peter",
        "Assi, Razan",
        "Gardier, R\u00e9my",
        "Vi\u00f1als, Roser",
        "Thiran, Jean-Philippe",
        "Segman, Ronen",
        "Benjamini, Yuval",
        "Bonne, Omer",
        "Hummel, Friedhelm Christoph",
        "Bavelier, Daphne",
        "Rancans, Elmars",
        "Nahum, Mor"
      ],
      "categories": null,
      "citations": 4,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1007/s00406-022-01464-y",
      "keywords": [
        "N Cognitive control",
        "N Video game",
        "N Transcranial direct current stimulation (tDCS)",
        "D016428 Journal Article",
        "N Feasibility",
        "N Major depressive disorder",
        "D000078325 Clinical Trial Protocol",
        "N Home-treatment"
      ],
      "number_of_pages": 14,
      "pages": "85-98",
      "publication": {
        "category": "Journal",
        "cite_score": 9.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1433-8491",
        "publisher": "D. Steinkopff-Verlag",
        "sjr": 1.356,
        "snip": 1.39,
        "subject_areas": [
          "Biological Psychiatry",
          "Psychiatry and Mental Health",
          "Pharmacology (medical)"
        ],
        "title": "European archives of psychiatry and clinical neuroscience"
      },
      "publication_date": "2022-10-22",
      "selected": false,
      "title": "Examining the synergistic effects of a cognitive control video game and a home-based, self-administered non-invasive brain stimulation on alleviating depression: the DiSCoVeR trial protocol.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85140446051&origin=inward"
      ]
    },
    {
      "abstract": "Brain-computer interfaces (BCIs) are being investigated as an access pathway to communication for individuals with physical disabilities, as the technology obviates the need for voluntary motor control. However, to date, minimal research has investigated the use of BCIs for children. Traditional BCI communication paradigms may be suboptimal given that children with physical disabilities may face delays in cognitive development and acquisition of literacy skills. Instead, in this study we explored emotional state as an alternative access pathway to communication. We developed a pediatric BCI to identify positive and negative emotional states from changes in hemodynamic activity of the prefrontal cortex (PFC). To train and test the BCI, 10 neurotypical children aged 8\u00e2\u0080\u009314 underwent a series of emotion-induction trials over four experimental sessions (one offline, three online) while their brain activity was measured with functional near-infrared spectroscopy (fNIRS). Visual neurofeedback was used to assist participants in regulating their emotional states and modulating their hemodynamic activity in response to the affective stimuli. Child-specific linear discriminant classifiers were trained on cumulatively available data from previous sessions and adaptively updated throughout each session. Average online valence classification exceeded chance across participants by the last two online sessions (with 7 and 8 of the 10 participants performing better than chance, respectively, in Sessions 3 and 4). There was a small significant positive correlation with online BCI performance and age, suggesting older participants were more successful at regulating their emotional state and/or brain activity. Variability was seen across participants in regards to BCI performance, hemodynamic response, and discriminatory features and channels. Retrospective offline analyses yielded accuracies comparable to those reported in adult affective BCI studies using fNIRS. Affective fNIRS-BCIs appear to be feasible for school-aged children, but to further gauge the practical potential of this type of BCI, replication with more training sessions, larger sample sizes, and end-users with disabilities is necessary. Copyright \u00c2\u00a9 2022 Floreani, Orlandi and Chau.",
      "authors": [
        "Floreani, E.D.",
        "Orlandi, S.",
        "Chau, T."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3389/fnhum.2022.938708",
      "keywords": [
        "functional near-infrared spectroscopy",
        "neurofeedback",
        "brain-computer interface",
        "alternative and augmentative communication",
        "affective state",
        "pediatric"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Frontiers in Human Neuroscience"
      },
      "publication_date": "2022-09-23",
      "selected": false,
      "title": "A pediatric near-infrared spectroscopy brain-computer interface based on the detection of emotional valence",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85139405095&origin=inward"
      ]
    },
    {
      "abstract": "OBJECTIVE OBJECTIVE Several studies showed that transcranial direct current stimulation (tDCS) enhances cognition in patients with mild cognitive impairment (MCI), however, whether tDCS leads to additional gains when combined with cognitive training remains unclear. This study aims to compare the effects of a concurrent tDCS-cognitive training intervention with either tDCS or cognitive training alone on a group of patients with MCI.\nMETHODS METHODS The study was a 3-parallel-arm study. The intervention consisted of 20 daily sessions of 20\u00a0minutes each. Patients (n\u00a0=\u00a062) received anodal tDCS to the left dorsolateral prefrontal cortex, cognitive training on 5 cognitive domains (orientation, attention, memory, language, and executive functions), or both. To examine intervention gains, we examined global cognitive functioning, verbal short-term memory, visuospatial memory, and verbal fluency pre- and post-intervention.\nRESULTS RESULTS All outcome measures improved after the intervention in the 3 groups. The improvement in global cognitive functioning and verbal fluency was significantly larger in patients who received the combined intervention. Instead, the intervention gain in verbal short-term memory and visuospatial memory was similar across the 3 groups.\nDISCUSSION CONCLUSIONS tDCS, regardless of the practicalities, could be an efficacious treatment in combination with cognitive training given the increased effectiveness of the combined treatment.\nCONCLUSIONS CONCLUSIONS Future studies will need to consider individual differences at baseline, including genetic factors and anatomical differences that impact the electric field generated by tDCS and should also consider the feasibility of at-home treatments consisting of the application of tDCS with cognitive training.",
      "authors": [
        "Pallanti, Stefano",
        "Grassi, Eleonora",
        "Knotkova, Helena",
        "Galli, Giulia"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1017/S1092852922000979",
      "keywords": [
        "N Noninvasive brain stimulation",
        "@UI",
        "N tDCS",
        "N mild cognitive impairment",
        "N cognitive enhancement",
        "N neuromodulation",
        "#text"
      ],
      "number_of_pages": 6,
      "pages": "1-6",
      "publication": {
        "category": "Journal",
        "cite_score": 6.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1092-8529",
        "publisher": "Cambridge University Press",
        "sjr": 0.912,
        "snip": 1.201,
        "subject_areas": [
          "Neurology (clinical)",
          "Psychiatry and Mental Health"
        ],
        "title": "CNS spectrums"
      },
      "publication_date": "2022-09-12",
      "selected": false,
      "title": "Transcranial direct current stimulation in combination with cognitive training in individuals with mild cognitive impairment: a controlled 3-parallel-arm study.",
      "urls": []
    },
    {
      "abstract": "Objective Approach Main results Significance . Temporal interference stimulation (TIS) has shown the potential as a new method for selective stimulation of deep brain structures in small animal experiments. However, it is challenging to deliver a sufficient temporal interference (TI) current to directly induce an action potential in the deep area of the human brain when electrodes are attached to the scalp because the amount of injection current is generally limited due to safety issues. Thus, we propose a novel method called epidural TIS (eTIS) to address this issue; in this method, the electrodes are attached to the epidural surface under the skull.. We employed finite element method (FEM)-based electric field simulations to demonstrate the feasibility of eTIS. We first optimized the electrode conditions to deliver maximum TI currents to each of the three different targets (anterior hippocampus, subthalamic nucleus, and ventral intermediate nucleus) based on FEM, and compared the stimulation focality between eTIS and transcranial TIS (tTIS). Moreover, we conducted realistic skull-phantom experiments for validating the accuracy of the computational simulation for eTIS.. Our simulation results showed that eTIS has the advantage of avoiding the delivery of TI currents over unwanted neocortical regions compared with tTIS for all three targets. It was shown that the optimized eTIS could induce neural action potentials at each of the three targets when a sufficiently large current equivalent to that for epidural cortical stimulation is injected. Additionally, the simulated results and measured results via the phantom experiments were in good agreement.. We demonstrated the feasibility of eTIS, facilitating more focalized and stronger electrical stimulation of deep brain regions than tTIS, with the relatively less invasive placement of electrodes than conventional deep brain stimulation via computational simulation and realistic skull phantom experiments.",
      "authors": [
        "Lee, Sangjun",
        "Park, Jimin",
        "Choi, Da Som",
        "Lim, Seokbeen",
        "Kwak, Youngjong",
        "Jang, Dong Pyo",
        "Kim, Dong Hwan",
        "Ji, Han Bi",
        "Choy, Young Bin",
        "Im, Chang-Hwan"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1088/1741-2552/ac8503",
      "keywords": [
        "N epidural electrical stimulation",
        "N temporal interference stimulation",
        "D016428 Journal Article",
        "N human skull phantom experiment",
        "N finite element method",
        "D013485 Research Support, Non-U.S. Gov't",
        "N optimization"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1741-2552",
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Journal of neural engineering"
      },
      "publication_date": "2022-09-06",
      "selected": false,
      "title": "Feasibility of epidural temporal interference stimulation for minimally invasive electrical deep brain stimulation: simulation and phantom experimental studies.",
      "urls": []
    },
    {
      "abstract": "This study examines nurses\u00e2\u0080\u0099 Continuance Intention (CI) to use electronic health records (EHRs) through a combination of three conceptual frameworks: the Unified Theory of Acceptance and Use of Technology (UTAUT), the theory of expectation-confirmation (ECT), and the Five-Factor Model (FFM). A model is developed to examine and predict the determinants of nurses\u00e2\u0080\u0099 CI to use EHRs, including top management support (TMS) and the FFM\u00e2\u0080\u0099s five personality domains. Data were collected from a survey of 497 nurses, which were analyzed using partial least squares. No significant relationship was found between TMS and CI. The study revealed that performance expectancy significantly mediated the influences of two different hypotheses of two predictors: agreeableness and openness to testing CI. A significant moderating impact of conscientiousness was found on the relationship between performance expectancy and CI and the relationship between social influence and CI. The findings of this study indicated that rigorous attention to the personality of individual nurses and substantial TMS could improve nurses\u00e2\u0080\u0099 CI to use EHRs. A literature gap was filled concerning the mediating effects of performance expectancy on the FFM-CI relationship, and the moderation effects of Conscientiousness on UTAUT constructs and CI are another addition to the literature. The results are expected to assist government agencies, health policymakers, and health institutions all over the globe in their attempts to understand the post-adoption use of EHRs. \u00c2\u00a9 2022 by the authors.",
      "authors": [
        "Alsyouf, Adi",
        "Ishak, Awanis Ku",
        "Lutfi, Abdalwali",
        "Alhazmi, Fahad Nasser",
        "Al-Okaily, Manaf"
      ],
      "categories": null,
      "citations": 13,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.3390/ijerph191711125",
      "keywords": [
        "N post-adoption",
        "N five-factor model",
        "D016428 Journal Article",
        "N UTAUT",
        "D013485 Research Support, Non-U.S. Gov't",
        "N electronic health records",
        "N nurses",
        "N continuance intention"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 5.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1660-4601",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.828,
        "snip": 1.28,
        "subject_areas": [
          "Pollution",
          "Public Health, Environmental and Occupational Health",
          "Health, Toxicology and Mutagenesis"
        ],
        "title": "International journal of environmental research and public health"
      },
      "publication_date": "2022-09-05",
      "selected": false,
      "title": "The Role of Personality and Top Management Support in Continuance Intention to Use Electronic Health Record Systems among Nurses.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85137600661&origin=inward"
      ]
    },
    {
      "abstract": "Mining can be the source and target of opportunities and threats of different natures exceeding the mine site perimeter, affecting the socio-ecological system and leading to social conflicts and entrepreneurial risks for mining companies. Hence, a mining project is a matter of land planning rather than a simple industrial object. Nevertheless, current mandatory risk and impact assessment methods are often performed on one project at a time, neglecting the coexistence of different mining activities and the socio-ecological vulnerability of the territory where mining takes place. This paper proposes an original risk-based approach to develop and compare different territorial mining scenarios (TMSs) to support land-planning strategies in mining territories, tested on the French Guiana gold mining sector. Five TMSs combining different mine types (e.g., legal artisanal, medium, large-scale mining, illegal mining) were developed for the same total amount of gold production at the watershed level. For each TMS, both accidental and ordinary risk scenarios were assessed through a GIS-based approach considering watershed socio-ecological vulnerability. Risks were finally weighted according to different stakeholders\u00e2\u0080\u0099 perception, and the TMSs were compared based on their global risk scores. Despite the multiple challenges highlighted, this paper highlights the feasibility of a methodological framework to support mining planning at the territory level. \u00c2\u00a9 2022 by the authors.",
      "authors": [
        "Scammacca, O.",
        "Mehdizadeh, R.",
        "Gunzburger, Y."
      ],
      "categories": null,
      "citations": 1,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3390/su141710476",
      "keywords": [
        "risk assessment",
        "gold mining",
        "French Guiana",
        "sustainability",
        "scenarios",
        "land planning"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Sustainability (Switzerland)"
      },
      "publication_date": "2022-09-01",
      "selected": false,
      "title": "Territorial Mining Scenarios for Sustainable Land-Planning: A Risk-Based Comparison on the Example of Gold Mining in French Guiana",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85137877190&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND ADHD is a common neurodevelopmental disorder with a pediatric prevalence of 5.2%.While medication treatment for ADHD is effective, it does not address all symptoms and a small but notable subgroup does not respond to medications. Adverse effects limit its use and some parents and participants resist use of medication. Thus, limitations of medication treatment for ADHD motivate searching for other therapeutic options. Transcranial Direct Current Stimulation (tDCS) has been suggested as a treatment for children with ADHD, with mixed results to date. Protocol variables employed, including combined use of cognitive training (CT) and scheduling of sessions, may explain diverse findings to date. The aim of this study was to examine safety, feasibility and efficacy of tDCS combined with CT provided three-times-per week for one-month to treat children with ADHD.\nMETHODS In a double blind, randomized, sham-controlled pilot study, 25 children with ADHD were randomized to receive 12 sessions of either anodal tDCS or sham-tDCS for 20\u00a0min combined with CT three-times-per-week for four weeks. The tDCS anode was over left dorsolateral prefrontal cortex (DLPFC) and cathode over vertex. Assessments were obtained prior to, after 6 sessions, 12 sessions and one-month after intervention.\nRESULTS No significant post-intervention differences were found between those receiving tDCS or sham-tDCS. Both groups demonstrated significant improvement on questionnaire measures of ADHD and executive function with mixed results seen on computerized performance measures. Overall, adverse effects were mild with no significant difference between groups. However, three children, all from the tDCS group, experienced headaches with two requiring temporary cessation and one requiring removal from the study.\nCONCLUSIONS Anodal tDCS to the DLPFC using the above protocol in children with ADHD did not demonstrate additional treatment benefits beyond that of CT.",
      "authors": [
        "Schertz, Mitchell",
        "Karni-Visel, Yael",
        "Genizi, Jacob",
        "Manishevitch, Hofit",
        "Lam, Menachem",
        "Akawi, Ashraf",
        "Dudai, Michal",
        "Fenton, Andr\u00e9 A",
        "Bikson, Marom"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.jpsychires.2022.08.022",
      "keywords": [
        "N Transcranial direct current stimulation (tDCS)",
        "N Randomized controlled trial",
        "D016428 Journal Article",
        "D052061 Research Support, N.I.H., Extramural",
        "N Dorsolateral prefrontal cortex (DLPFC)",
        "D013485 Research Support, Non-U.S. Gov't",
        "D016449 Randomized Controlled Trial",
        "N Attention deficit hyperactivity disorder (ADHD)",
        "N Cognitive training"
      ],
      "number_of_pages": 11,
      "pages": "302-312",
      "publication": {
        "category": "Journal",
        "cite_score": 6.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1879-1379",
        "publisher": "Elsevier Ltd.",
        "sjr": 1.554,
        "snip": 1.364,
        "subject_areas": [
          "Biological Psychiatry",
          "Psychiatry and Mental Health"
        ],
        "title": "Journal of psychiatric research"
      },
      "publication_date": "2022-09-01",
      "selected": false,
      "title": "Transcranial Direct Current Stimulation (tDCS) in children with ADHD: A randomized, sham-controlled pilot study.",
      "urls": []
    },
    {
      "abstract": "BACKGROUND UNASSIGNED Tinnitus is a common symptom, affecting about 10-15% of the adult population. When input from the somatosensory system can influence and/or elicit tinnitus, this type of subjective tinnitus is called somatosensory tinnitus. Recently, a new type of bimodal neurostimulation treatment has shown promising results for a specific subgroup within the somatosensory tinnitus population. It is, however, not clear if this bimodal stimulation is also effective in patients with other types of subjective tinnitus.\nAIM UNASSIGNED The aim of this study was to evaluate the feasibility and efficacy of non-invasive bimodal auditory-somatosensory stimulation in reducing tinnitus severity among a general population of people with subjective tinnitus.\nMETHODS UNASSIGNED via Chronic subjective tinnitus patients were recruited from the ENT department of the Antwerp University Hospital. Somatosensory stimulation was delivered by Transcutaneous Electrical Nerve Stimulation (TENS), and it was combined with auditory stimulation  headphones. The therapy comprised six sessions of thirty minutes twice a week for a period of 3 consecutive weeks. Follow up measurements were scheduled 9-12 weeks after the last treatment session. The change of the Tinnitus Functional Index (TFI) score, a questionnaire evaluating tinnitus burden and effects on the quality of life, was the primary outcome measure.\nRESULTS UNASSIGNED Twenty-nine patients were enrolled in the study. A linear mixed-effects model was used to analyze the efficacy of bimodal treatment. The results of this analysis showed a statistically significant decrease (by 6, 9 points) in average TFI score at the follow up visit when compared to baseline. The ability to modulate tinnitus did not have an influence on the treatment results.\nCONCLUSION UNASSIGNED Our study showed that bimodal stimulation is a feasible and safe method of tinnitus treatment. The method might be an effective treatment for some participants with tinnitus, especially those who have accompanying neck/temporomandibular problems, although, the evidence from this trial is quite weak. Additional research is needed toward establishing the optimal treatment protocol, as well as selecting the most appropriate inclusion criteria.",
      "authors": [
        "Spencer, Shikha",
        "Mielczarek, Marzena",
        "Olszewski, Jurek",
        "Sereda, Magdalena",
        "Joossen, Iris",
        "Vermeersch, Hanne",
        "Gilles, Annick",
        "Michiels, Sarah"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3389/fnins.2022.971633",
      "keywords": [
        "N tinnitus",
        "N treatment",
        "@UI",
        "N auditory",
        "N bimodal stimulation",
        "N electrical",
        "#text",
        "N somatosensory"
      ],
      "number_of_pages": null,
      "pages": "971633",
      "publication": {
        "category": "Journal",
        "cite_score": 6.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1662-4548",
        "publisher": "Frontiers Media S.A.",
        "sjr": 1.161,
        "snip": 1.221,
        "subject_areas": [
          "Neuroscience (all)"
        ],
        "title": "Frontiers in neuroscience"
      },
      "publication_date": "2022-08-24",
      "selected": false,
      "title": "Effectiveness of bimodal auditory and electrical stimulation in patients with tinnitus: A feasibility study.",
      "urls": []
    },
    {
      "abstract": "Regular exercise protects against overweight/obesity as well as numerous chronic diseases. Yet, less than half of Americans exercise sufficiently. Elevated levels of depressive symptoms have been identified as an important correlate of physical inactivity as well as poor adherence to exercise programs. Individuals with depression are less sensitive to rewards and demonstrate an attentional bias toward negative stimuli. These, and other features of depression, may place them at increased risk for effectively managing the affective experience of exercise. Lower baseline levels of activation of the left (vs right) frontal cortex, an area implicated in affect regulation, have also been found in depression, potentially pointing to this region as a potential target for intervening on affect regulation during exercise. Transcranial direct current stimulation (tDCS) has shown promise in impacting a variety of cognitive and affective processes in a large number of individuals, including people with depression. Some findings have suggested that tDCS targeting the left dorsolateral prefrontal cortex (DLPFC), specifically, may improve emotion regulation. Transcranial direct current stimulation could theoretically be a novel and potentially promising approach to improving the affective experience of exercise, thereby increasing exercise adherence among individuals with depressive symptoms. Here we present the rationale, design, and baseline characteristics of a pilot randomized controlled trial of tDCS versus sham delivered 3x/week for 8 weeks in the context of supervised aerobic exercise (AE) program among 51 low-active individuals with elevated depressive symptoms (86.3% female; mean age\u00a0=\u00a049.5). Follow-up assessments were conducted at end of treatment, and three and six months after enrollment to examine changes in levels of objectively-measured moderate-to-vigorous physical activity (MVPA). If effective, this approach could have high public health impact on preventing obesity and chronic diseases among these at-risk individuals.",
      "authors": [
        "Abrantes, Ana M",
        "Garnaat, Sarah L",
        "Stein, Michael D",
        "Uebelacker, Lisa A",
        "Williams, David M",
        "Carpenter, Linda L",
        "Greenberg, Benjamin D",
        "Desaulniers, Julie",
        "Audet, Daniel"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.conctc.2022.100972",
      "keywords": [],
      "number_of_pages": null,
      "pages": "100972",
      "publication": {
        "category": "Journal",
        "cite_score": 2.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2451-8654",
        "publisher": "Elsevier Inc.",
        "sjr": 0.642,
        "snip": 0.662,
        "subject_areas": [
          "Pharmacology"
        ],
        "title": "Contemporary clinical trials communications"
      },
      "publication_date": "2022-08-20",
      "selected": false,
      "title": "A pilot randomized clinical trial of tDCS for increasing exercise engagement in individuals with elevated depressive symptoms: Rationale, design, and baseline characteristics.",
      "urls": []
    },
    {
      "abstract": "Neuroimaging studies suggest that the right dorsolateral prefrontal cortex (rDLPFC) is an important brain area involved in fairness-related decision-making. In the present study, we used transcranial direct current stimulation (tDCS) over the rDLPFC to investigate the effects of changed cortical excitability on fairness norm enforcement in social decision-making. Participants received anodal, cathodal or sham stimulation before performing a modified ultimatum game task, in which participants were asked to accept or reject the proposer's offer and self-rate the intensity of their anger at offers on a 7-point scale. The results showed that the rejection rate of unfair offers and anger level were higher in the anodal compared to the sham and cathodal groups and that the level of anger at unfair offers can predict the rejection rate. Furthermore, the fairness effect of RTs was more prominent in the anodal group than in the sham and cathodal groups. Our findings validate the causal role of the rDLPFC in fairness-related decision-making through tDCS, suggesting that strengthening the rDLPFC increases individuals' reciprocal fairness in social decision-making, both in subjective rating and behaviors.",
      "authors": [
        "Hu, Xinmu",
        "Zhang, Yu",
        "Liu, Xiaoqing",
        "Guo, Yunfei",
        "Liu, Chao",
        "Mai, Xiaoqin"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1093/scan/nsac004",
      "keywords": [
        "D016428 Journal Article",
        "D013485 Research Support, Non-U.S. Gov't",
        "N ultimatum game (UG)",
        "N transcranial direct current stimulation (tDCS)",
        "N right dorsolateral prefrontal cortex (rDLPFC)",
        "N fairness-related decision-making"
      ],
      "number_of_pages": 8,
      "pages": "695-702",
      "publication": {
        "category": "Journal",
        "cite_score": 6.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1749-5024",
        "publisher": "Oxford University Press",
        "sjr": 1.602,
        "snip": 1.285,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Experimental and Cognitive Psychology"
        ],
        "title": "Social cognitive and affective neuroscience"
      },
      "publication_date": "2022-08-01",
      "selected": false,
      "title": "Effects of transcranial direct current stimulation over the right dorsolateral prefrontal cortex on fairness-related decision-making.",
      "urls": []
    },
    {
      "abstract": "Some research suggests that distress, secondary to isolation and fear following COVID-19 infection, can negatively affect the long-term more than the COVID-19 infection itself. This narrative review aims to provide a global view on the neuropsychiatric consequences of COVID-19 that can be ascribed to several factors, ranging from the direct effect of infection, to the body's responses against the infection, or to the psychological sequelae of social isolation, unemployment, and fear for one's health and livelihood. Current findings show that the more severe the respiratory infection, the more likely are central nervous system (CNS) complications regarding the infection itself. The immune reactions to the infection may result in symptoms similar to chronic fatigue as well as neurocognitive deficits, which last long after the infection is gone. An increase in symptoms of depression, anxiety, and trauma-related stress may also follow upon economic fears and isolation from friends and family. The consequences of the pandemic are not limited to adults; children learning remotely and away from classmates and routine activities may develop adjustment disorders, acute stress disorder, and a variety of manifestations of grief. A summary of case reports suggests that COVID-19-related stress, economic recession, and political unrest increase the risk of suicidal behaviors and acts of violence. However, it is unknown whether manifestations of mental disorders result from social causes or whether CNS complications may be responsible.",
      "authors": [
        "Pandi-Perumal, Seithikurippu R",
        "Zaki, Nevin F W",
        "Qasim, Mohammad",
        "Elsayed Morsy, Nesreen",
        "Manzar, Md Dilshad",
        "BaHammam, Ahmed S",
        "Jahrami, Haitham",
        "Ramasubramanian, Chellamuthu",
        "Karthikeyan, Ramanujam",
        "Supasitthumrong, Thitiporn",
        "Moscovitch, Adam",
        "Trakht, Ilya",
        "Gupta, Ravi",
        "Narasimhan, Meera",
        "Partonen, Timo",
        "Reiter, Russel J",
        "Morris, Gerwyn",
        "Berk, Michael",
        "Kennedy, Sidney H",
        "Stein, Dan J",
        "Stahl, Stephen M",
        "Charney, Dennis S",
        "Seeman, Mary V"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.5152/alphapsychiatry.2022.21783",
      "keywords": [
        "D016428 Journal Article",
        "N COVID-19",
        "N sleep",
        "D016454 Review",
        "N psychiatry",
        "N SARS-CoV-2",
        "N mental illness"
      ],
      "number_of_pages": 11,
      "pages": "144-154",
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2757-8038",
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Alpha psychiatry"
      },
      "publication_date": "2022-07-01",
      "selected": false,
      "title": "Neuropsychiatric Consequences of COVID-19 Pandemic: A Synthetic Review from a Global Perspective.",
      "urls": []
    },
    {
      "abstract": "Objective: To understand the impact of the Coronavirus Disease-2019 (COVID-19) pandemic on seizure frequency in persons with epilepsy with a Responsive Neurostimulation (RNS) system implanted. Methods: Weekly long episode counts (LEC) were used as a proxy for seizures for six months pre-COVID-19 and during the COVID-19 period. Telephone surveys and chart reviews were conducted to assess patient mental health during the pandemic. The change in LEC between the two time periods was correlated to reported stressors. Results: Twenty patients were included. Comparing the pre-COVID-19 period to the COVID-19 period, we found that only 5 (25%) patients had increased seizures, which was positively correlated with change in anti-seizure medications (ASM, p = 0.03) and bitemporal seizures (p = 0.03). Increased seizures were not correlated to anxiety (p = 1.00), depression (p = 0.58), and sleep disturbances (p = 1.00). The correlation between RNS-detected and patient-reported seizures was poor (p = 0.32). Conclusions: Most of our patients did not have an increase in seizures following the COVID-19 pandemic. Changes in ASM and bitemporal seizures were positively correlated to increased LEC. There was no correlation between pandemic-related stress and seizures in those found to have increased seizures. Significance: This is the first study correlating RNS-derived objective LECs with patient self-reports and potential seizure risk factors during the COVID-19 pandemic. \u00c2\u00a9 2022 International Federation of Clinical Neurophysiology",
      "authors": [
        "Karakas, C.",
        "Ward, R.",
        "Hegazy, M.",
        "Skrehot, H.",
        "Haneef, Z."
      ],
      "categories": null,
      "citations": 2,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1016/j.clinph.2022.05.003",
      "keywords": [
        "Pandemic",
        "RNS",
        "Epilepsy",
        "Stressor",
        "Long episode",
        "COVID-19"
      ],
      "number_of_pages": 8,
      "pages": "106-113",
      "publication": {
        "category": "Journal",
        "cite_score": 7.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "13882457",
        "publisher": "Elsevier Ireland Ltd",
        "sjr": 1.212,
        "snip": 1.482,
        "subject_areas": [
          "Physiology (medical)",
          "Sensory Systems",
          "Neurology (clinical)",
          "Neurology"
        ],
        "title": "Clinical Neurophysiology"
      },
      "publication_date": "2022-07-01",
      "selected": false,
      "title": "Seizure control during the COVID-19 pandemic: Correlating Responsive Neurostimulation System data with patient reports",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85130752174&origin=inward"
      ]
    },
    {
      "abstract": "Terror management strategies (TMS) are assumed to affect social prejudice. In a prior study, positive death valence in wave 1 reduced gender-related stereotypes in wave 2. Psychosocial intervention against prejudice requires a deeper understanding of the terror management process. We investigated the relationships between death anxiety, death valence, mortality salience and TMS in a mixed method study. Participants showed complex emotions in the face of death, including fear, anxiety, sadness and ambivalent calm. Positive death valence was associated with more conscious fear, but with less implicit death anxiety, while negative death valence was associated with more death denial. In conclusion, we propose death anxiety as a distal precursor and death valence as a proximate precursor of the plural TMS that are triggered by mortality salience. \u00c2\u00a9 The Author(s) 2022.",
      "authors": [
        "Stiller, Mel",
        "Di Masso, Andr\u00e9s"
      ],
      "categories": null,
      "citations": 1,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1177/00302228221108300",
      "keywords": [
        "@UI",
        "N death valence",
        "N death denial",
        "N death acceptance",
        "N terror management",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "302228221108300",
      "publication": {
        "category": "Journal",
        "cite_score": 3.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1541-3764",
        "publisher": "SAGE Publications Inc.",
        "sjr": 0.48,
        "snip": 1.234,
        "subject_areas": [
          "Health (social science)",
          "Critical Care and Intensive Care Medicine",
          "Life-span and Life-course Studies"
        ],
        "title": "Omega (United States)"
      },
      "publication_date": "2022-06-20",
      "selected": false,
      "title": "The Power of Death Valence: A Revised Terror Management Process.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85132938163&origin=inward"
      ]
    },
    {
      "abstract": "Background: The degree of efficacy, safety, quality, and certainty of meta-analytic evidence of biological non-pharmacological treatments in mental disorders is unclear. Methods: We conducted an umbrella review (PubMed/Cochrane Library/PsycINFO-04-Jul-2021, PROSPERO/CRD42020158827) for meta-analyses of randomized controlled trials (RCTs) on deep brain stimulation (DBS), transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), electro-convulsive therapy (ECT), and others. Co-primary outcomes were standardized mean differences (SMD) of disease-specific symptoms, and acceptability (for all-cause discontinuation). Evidence was assessed with AMSTAR/AMSTAR-Content/GRADE. Results: We selected 102 meta-analyses. Effective interventions compared to sham were in depressive disorders: ECT (SMD=0.91/GRADE=moderate), TMS (SMD=0.51/GRADE=moderate), tDCS (SMD=0.46/GRADE=low), DBS (SMD=0.42/GRADE=very low), light therapy (SMD=0.41/GRADE=low); schizophrenia: ECT (SMD=0.88/GRADE=moderate), tDCS (SMD=0.45/GRADE=very low), TMS (prefrontal theta-burst, SMD=0.58/GRADE=low; left-temporoparietal, SMD=0.42/GRADE=low); substance use disorder: TMS (high frequency-dorsolateral-prefrontal-deep (SMD=1.16/GRADE=moderate), high frequency-left dorsolateral-prefrontal (SMD=0.77/GRADE=very low); OCD: DBS (SMD=0.89/GRADE=moderate), TMS (SMD=0.64/GRADE=very low); PTSD: TMS (SMD=0.46/GRADE=moderate); generalized anxiety disorder: TMS (SMD=0.68/GRADE=low); ADHD: tDCS (SMD=0.23/GRADE=moderate); autism: tDCS (SMD=0.97/GRADE=very low). No significant differences for acceptability emerged. Median AMSTAR/AMSTAR-Content was 8/2 (suggesting high-quality meta-analyses/low-quality RCTs), GRADE low. Discussion: Despite limited certainty, biological non-pharmacological interventions are effective and safe for numerous mental conditions. Results inform future research, and guidelines. Funding: None. \u00c2\u00a9 2022 Elsevier Ltd",
      "authors": [
        "Rosson, Stella",
        "de Filippis, Renato",
        "Croatto, Giovanni",
        "Collantoni, Enrico",
        "Pallottino, Simone",
        "Guinart, Daniel",
        "Brunoni, Andre R",
        "Dell'Osso, Bernardo",
        "Pigato, Giorgio",
        "Hyde, Joshua",
        "Brandt, Valerie",
        "Cortese, Samuele",
        "Fiedorowicz, Jess G",
        "Petrides, Georgios",
        "Correll, Christoph U",
        "Solmi, Marco"
      ],
      "categories": null,
      "citations": 30,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1016/j.neubiorev.2022.104743",
      "keywords": [
        "N Deep brain stimulation",
        "N Transcranial magnetic stimulation",
        "N Mental health",
        "N Light therapy",
        "N DBS",
        "D016428 Journal Article",
        "N TMS",
        "N Transcranial direct current stimulation",
        "N Electro-convulsive therapy",
        "D016454 Review",
        "N VNS",
        "N Meta-analysis",
        "N Umbrella review",
        "N Vagus nerve stimulation",
        "N Biological non-pharmacological treatments",
        "N TDCS",
        "N ECT"
      ],
      "number_of_pages": null,
      "pages": "104743",
      "publication": {
        "category": "Journal",
        "cite_score": 13.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1873-7528",
        "publisher": "Elsevier Ltd.",
        "sjr": 2.599,
        "snip": 2.49,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Behavioral Neuroscience",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Neuroscience and biobehavioral reviews"
      },
      "publication_date": "2022-06-14",
      "selected": false,
      "title": "Brain stimulation and other biological non-pharmacological interventions in mental disorders: An umbrella review.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85132871111&origin=inward"
      ]
    },
    {
      "abstract": "We are in the midst of a mental health crisis with major depressive disorder being the most prevalent among mental health disorders and up to 30% of patients not responding to first-line treatments. Noninvasive Brain Stimulation (NIBS) techniques have proven to be effective in treating depression. However, there is a fundamental problem of scale. Currently, any type of NIBS treatment requires patients to repeatedly visit a clinic to receive brain stimulation by trained personnel. This is an often-insurmountable barrier to both patients and healthcare providers in terms of time and cost. In this perspective, we assess to what extent Transcranial Electrical Stimulation (TES) might be administered with remote supervision in order to address this scaling problem and enable neuroenhancement of mental resilience at home. Social, ethical, and technical challenges relating to hardware- and software-based solutions are discussed alongside the risks of stimulation under- or over-use. Solutions to provide users with a safe and transparent ongoing assessment of aptitude, tolerability, compliance, and/or misuse are proposed, including standardized training, eligibility screening, as well as compliance and side effects monitoring. Looking into the future, such neuroenhancement could be linked to prevention systems which combine home-use TES with digital sensor and mental monitoring technology to index decline in mental wellbeing and avoid relapse. Despite the described social, ethical legal, and technical challenges, the combination of remotely supervised, at-home TES setups with dedicated artificial intelligence systems could be a powerful weapon to combat the mental health crisis by bringing personalized medicine into people\u00e2\u0080\u0099s homes. Copyright \u00c2\u00a9 2022 Paneva, Leunissen, Schuhmann, de Graaf, J\u00c3\u00b8nsson, Onarheim and Sack.",
      "authors": [
        "Paneva, Jasmina",
        "Leunissen, Inge",
        "Schuhmann, Teresa",
        "de Graaf, Tom A",
        "J\u00f8nsson, Morten G\u00f8rtz",
        "Onarheim, Balder",
        "Sack, Alexander T"
      ],
      "categories": null,
      "citations": 3,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.3389/fnhum.2022.838187",
      "keywords": [
        "N noninvasive brain stimulation (NIBS)",
        "@UI",
        "N relapse prevention",
        "N major depressive disorder (MDD)",
        "N mental resilience",
        "N transcranial direct current stimulation (tDCS)",
        "N at-home TES",
        "#text",
        "N transcranial electrical stimulation (TES)"
      ],
      "number_of_pages": null,
      "pages": "838187",
      "publication": {
        "category": "Journal",
        "cite_score": 4.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1662-5161",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.787,
        "snip": 1.033,
        "subject_areas": [
          "Psychiatry and Mental Health",
          "Neurology",
          "Biological Psychiatry",
          "Neuropsychology and Physiological Psychology",
          "Behavioral Neuroscience"
        ],
        "title": "Frontiers in human neuroscience"
      },
      "publication_date": "2022-06-09",
      "selected": false,
      "title": "Using Remotely Supervised At-Home TES for Enhancing Mental Resilience.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85133424136&origin=inward"
      ]
    },
    {
      "abstract": "OBJECTIVES Transcranial direct current stimulation (tDCS) of the right dorsolateral prefrontal cortex has been hypothesized to reduce tinnitus severity by modifying cortical activity in brain regions associated with the perception of tinnitus. However, individual response to tDCS has proven to be variable. We investigated the feasibility of using random forest classification to predict the response to high-definition (HD) tDCS for tinnitus relief.\nDESIGN A retrospective analysis was performed on a dataset consisting of 99 patients with subjective tinnitus receiving six consecutive sessions of HD-tDCS at the Antwerp University Hospital. A baseline assessment consisted of pure-tone audiometry and a set of questionnaires including the Tinnitus Functional Index (TFI), Hospital Anxiety and Depression Scale, and Edinburgh Handedness Inventory. Random forest classification was applied to predict, based on baseline questionnaire scores and hearing levels, whether each individual responded positively to the treatment (defined as a decrease of at least 13 points on the TFI). Further testing of the model was performed on an independent cohort of 32 patients obtained from the tinnitus center at the University of Regensburg.\nRESULTS Twenty-four participants responded positively to the HD-tDCS treatment. The random forest classifier predicted treatment response with an accuracy of 85.71% (100% sensitivity, 81.48% specificity), significantly outperforming a more traditional logistic regression approach. Performance of the classifier on an independent cohort was slightly but not significantly above chance level (71.88% accuracy, 66.67% sensitivity, 73.08% specificity). Feature importance analyses revealed that baseline tinnitus severity, co-occurrence of depressive symptoms and handedness were the most important predictors of treatment response. Baseline TFI scores were significantly higher in responders than in nonresponders.\nCONCLUSIONS The proposed random forest classifier predicted treatment response with a high accuracy, significantly outperforming a more traditional statistical approach. Machine learning methods to predict treatment response might ultimately be used in a clinical setting to guide targeted treatment recommendations for individual tinnitus patients.",
      "authors": [
        "Cardon, Emilie",
        "Jacquemin, Laure",
        "Schecklmann, Martin",
        "Langguth, Berthold",
        "Mertens, Griet",
        "Vanderveken, Olivier M",
        "Lammers, Marc",
        "Van de Heyning, Paul",
        "Van Rompaey, Vincent",
        "Gilles, Annick"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1097/AUD.0000000000001246",
      "keywords": [],
      "number_of_pages": 8,
      "pages": "1816-1823",
      "publication": {
        "category": "Journal",
        "cite_score": 5.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1538-4667",
        "publisher": "Lippincott Williams and Wilkins Ltd.",
        "sjr": 1.273,
        "snip": 1.895,
        "subject_areas": [
          "Speech and Hearing",
          "Otorhinolaryngology"
        ],
        "title": "Ear and hearing"
      },
      "publication_date": "2022-06-07",
      "selected": false,
      "title": "Random Forest Classification to Predict Response to High-Definition Transcranial Direct Current Stimulation for Tinnitus Relief: A Preliminary Feasibility Study.",
      "urls": []
    },
    {
      "abstract": "Attempts to enhance human memory and learning ability have a long tradition in science. This topic has recently gained substantial attention because of the increasing percentage of older individuals worldwide and the predicted rise of age-associated cognitive decline in brain functions. Transcranial brain stimulation methods, such as transcranial magnetic (TMS) and transcranial electric (tES) stimulation, have been extensively used in an effort to improve cognitive functions in humans. Here we summarize the available data on low-intensity tES for this purpose, in comparison to repetitive TMS and some pharmacological agents, such as caffeine and nicotine. There is no single area in the brain stimulation field in which only positive outcomes have been reported. For self-directed tES devices, how to restrict variability with regard to efficacy is an essential aspect of device design and function. As with any technique, reproducible outcomes depend on the equipment and how well this is matched to the experience and skill of the operator. For self-administered non-invasive brain stimulation, this requires device designs that rigorously incorporate human operator factors. The wide parameter space of non-invasive brain stimulation, including dose (e.g., duration, intensity (current density), number of repetitions), inclusion/exclusion (e.g., subject's age), and homeostatic effects, administration of tasks before and during stimulation, and, most importantly, placebo or nocebo effects, have to be taken into account. The outcomes of stimulation are expected to depend on these parameters and should be strictly controlled. The consensus among experts is that low-intensity tES is safe as long as tested and accepted protocols (including, for example, dose, inclusion/exclusion) are followed and devices are used which follow established engineering risk-management procedures. Devices and protocols that allow stimulation outside these parameters cannot claim to be \"safe\" where they are applying stimulation beyond that examined in published studies that also investigated potential side effects. Brain stimulation devices marketed for consumer use are distinct from medical devices because they do not make medical claims and are therefore not necessarily subject to the same level of regulation as medical devices (i.e., by government agencies tasked with regulating medical devices). Manufacturers must follow ethical and best practices in marketing tES stimulators, including not misleading users by referencing effects from human trials using devices and protocols not similar to theirs.",
      "authors": [
        "Antal, Andrea",
        "Luber, Bruce",
        "Brem, Anna-Katharine",
        "Bikson, Marom",
        "Brunoni, Andre R",
        "Cohen Kadosh, Roi",
        "Dubljevi\u0107, Veljko",
        "Fecteau, Shirley",
        "Ferreri, Florinda",
        "Fl\u00f6el, Agnes",
        "Hallett, Mark",
        "Hamilton, Roy H",
        "Herrmann, Christoph S",
        "Lavidor, Michal",
        "Loo, Collen",
        "Lustenberger, Caroline",
        "Machado, Sergio",
        "Miniussi, Carlo",
        "Moliadze, Vera",
        "Nitsche, Michael A",
        "Rossi, Simone",
        "Rossini, Paolo M",
        "Santarnecchi, Emiliano",
        "Seeck, Margitta",
        "Thut, Gregor",
        "Turi, Zsolt",
        "Ugawa, Yoshikazu",
        "Venkatasubramanian, Ganesan",
        "Wenderoth, Nicole",
        "Wexler, Anna",
        "Ziemann, Ulf",
        "Paulus, Walter"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.cnp.2022.05.002",
      "keywords": [
        "N EEG, electroencephalography",
        "N SMA, supplementary motor cortex",
        "N NIBS, noninvasive brain stimulation",
        "N PET, positron emission tomography",
        "N QPS, quadripulse stimulation",
        "N MCI, mild cognitive impairment",
        "N FCC, Federal Communications Commission",
        "N tACS",
        "N IFCN, International Federation of Clinical Neurophysiology",
        "N Home-stimulation",
        "N OTC, Over-The-Counter",
        "N LTD, long-term depression",
        "D016454 Review",
        "N PAS, paired associative stimulation",
        "N MEP, motor evoked potential",
        "N SAE, serious adverse event",
        "N PPC, posterior parietal cortex",
        "N tRNS, transcranial random noise stimulation",
        "N RMT, resting motor threshold",
        "N LTP, long-term potentiation",
        "N DIY, Do-It-Yourself",
        "D016428 Journal Article",
        "N tDCS",
        "N Neuroenhancement",
        "N MDD, Medical Device Directive",
        "N tES, transcranial electric stimulation",
        "N FDA, (U.S.) Food and Drug Administration",
        "N rTMS, repetitive transcranial magnetic stimulation",
        "N TBS, theta-burst stimulation",
        "N DLPFC, dorsolateral prefrontal cortex",
        "N EMG, electromyography",
        "N tACS, transcranial alternating current stimulation",
        "N MDR, Medical Device Regulation",
        "N DARPA, Defense Advanced Research Projects Agency",
        "N tDCS, transcranial direct current stimulation",
        "N DIY stimulation",
        "N TMS, transcranial magnetic stimulation",
        "N Cognitive enhancement",
        "N BDNF, brain derived neurotrophic factor",
        "N AD, Alzheimer\u2019s Disease",
        "N MRI, magnetic resonance imaging",
        "N Transcranial brain stimulation"
      ],
      "number_of_pages": 20,
      "pages": "146-165",
      "publication": {
        "category": "Journal",
        "cite_score": 4.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2467-981X",
        "publisher": "Elsevier BV",
        "sjr": 0.575,
        "snip": 1.37,
        "subject_areas": [
          "Physiology (medical)",
          "Neurology (clinical)",
          "Neurology"
        ],
        "title": "Clinical neurophysiology practice"
      },
      "publication_date": "2022-05-25",
      "selected": false,
      "title": "Non-invasive brain stimulation and neuroenhancement.",
      "urls": []
    },
    {
      "abstract": "Amygdala NeuroFeedback (NF) have the potential of being a valuable non-invasive intervention tool in many psychiatric disporders. However, the feasibility and best practices of this method have not been systematically examined. The current article presents a review of amygdala-NF studies, an analytic summary of study design parameters, and examination of brain mechanisms related to successful amygdala-NF performance. A meta-analysis of 33 publications showed that real amygdala-NF facilitates learned modulation compared to control conditions. In addition, while variability in study dsign parameters is high, these design choices are implicitly organized by the targeted valence domain (positive or negative). However, in most cases the neuro-behavioral effects of targeting such domains were not directly assessed. Lastly, re-analyzing six data sets of amygdala-fMRI-NF revealed that successful amygdala down-modulation is coupled with deactivation of the posterior insula and nodes in the Default-Mode-Network. Our findings suggest that amygdala self-modulation can be acquired using NF. Yet, additional controlled studies, relevant behavioral tasks before and after NF intervention, and neural 'target engagement' measures are critically needed to establish efficacy and specificity. In addition, the fMRI analysis presented here suggest that common accounts regarding the brain network involved in amygdala NF might reflect unsuccessful modulation attempts rather than successful modulation.",
      "authors": [
        "Goldway, Noam",
        "Jalon, Itamar",
        "Keynan, Jackob N",
        "Hellrung, Lydia",
        "Horstmann, Annette",
        "Paret, Christian",
        "Hendler, Talma"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.neubiorev.2022.104694",
      "keywords": [
        "N Brain Computer Interface",
        "D016428 Journal Article",
        "N Real-time fMRI",
        "D016454 Review",
        "D013485 Research Support, Non-U.S. Gov't",
        "N RDoC",
        "N Neurofeedback",
        "N Meta-analysis",
        "D017418 Meta-Analysis",
        "N Amygdala"
      ],
      "number_of_pages": null,
      "pages": "104694",
      "publication": {
        "category": "Journal",
        "cite_score": 13.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1873-7528",
        "publisher": "Elsevier Ltd.",
        "sjr": 2.599,
        "snip": 2.49,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Behavioral Neuroscience",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Neuroscience and biobehavioral reviews"
      },
      "publication_date": "2022-05-24",
      "selected": false,
      "title": "Feasibility and utility of amygdala neurofeedback.",
      "urls": []
    },
    {
      "abstract": "Context: Given the growing interest in digital health interventions (DHI) and increasing number of commercial products targeting youth with ADHD, we conducted a mapping review of the current evidence for DHI for children and adolescents with ADHD. Objective: To identify DHI designed to support or extend ADHD treatment. Data sources: Electronic databases (PubMed, ACM Digital Library, and IEEE Xplore) were searched for studies published in English from January 1, 2004, through January 1, 2022. Search keywords included ADHD and terms for technology (e.g., digital, smartphone, computer) and treatment (e.g., treatment, intervention, cognitive training, neurofeedback). Study selection: Two reviewers reviewed titles, abstracts, and articles. Prior reviews and meta-analyses for two clusters of DHI (cognitive training and neurofeedback) were identified and summarized. The remaining 1,246 records focused on other DHI, and 51 studies representing 16 countries met eligibility criteria. These DHI addressed functioning in domains commonly targeted in treatments for ADHD and were classified based on targeted domains, users, technological platforms, and intended settings. Results: The 51 DHI studies described interventions delivered via serious games or e-learning, the web, mHealth, telehealth, and augmented or virtual reality. DHI targeted a range of domains relevant to ADHD treatment: cognition, social-emotional skills, behavior management, academic/organizational skills, medication adherence, vocational skills, motor behaviors, and clinical care. Twelve well-designed, adequately powered randomized clinical trials reported positive outcomes from interventions delivered using telehealth, the web, mHealth applications, exergaming, and clinician decision-making support tools. Limitations: Keyword selection, terminology usage, and digital libraries in the DHI space were not consistent within or across disciplines, nor across countries, which limited study identification. Few studies had evidence from randomized, controlled trials which limited information on the efficacy of most tools. Conclusions: Research supports the use of several DHI and describes emerging DHI, not yet available for implementation in community settings. Our review provides a map of the current field, identifies gaps and potentials for future research, and highlights the need to increase translation from early designs to robust evidence-based products. \u00c2\u00a9 2022 The Authors",
      "authors": [
        "Lakes, K.D.",
        "Cibrian, F.L.",
        "Schuck, S.E.B.",
        "Nelson, M.",
        "Hayes, G.R."
      ],
      "categories": null,
      "citations": 9,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1016/j.chbr.2022.100174",
      "keywords": [
        "Attention",
        "Digital health intervention",
        "Cognition",
        "Behavior",
        "Treatment",
        "ADHD"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Computers in Human Behavior Reports"
      },
      "publication_date": "2022-05-01",
      "selected": false,
      "title": "Digital health interventions for youth with ADHD: A mapping review",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85127238383&origin=inward"
      ]
    },
    {
      "abstract": "Background: Behavioral approaches are central to the preventive treatment of migraine but empirical evidence regarding efficacy and effectiveness is still sparse. This study aimed to evaluate the efficacy of a newly developed migraine-specific, integrative cognitive-behavioral therapy program (miCBT) combining several approaches (trigger and stress management, coping with fear of attacks, relaxation training) by comparing it with a single behavioral approach (relaxation training, RLX) as an active control group and a waiting-list control group (WLC). Methods: In a three-armed open-label randomized controlled trial, 121 adults with migraine were assigned to either miCBT, RLX or WLC. The outpatient group therapy (miCBT or RLX) consisted of seven sessions each 90 min. Participants who completed the WLC were subsequently randomized to one of the two treatment groups. Primary outcomes were headache days, headache-related disability, emotional distress, and self-efficacy. The baseline was compared to post-treatment, and followed by assessments 4- and 12-months post-treatment to compare miCBT and RLX. Results: Mixed-model analyses (intention-to-treat sample, 106 participants) showed significantly stronger pre-post improvements in self-efficacy (assessed by the Headache Management Self-Efficacy Scale, HMSE-G-SF) in both treatment groups compared to the WLC (mean difference at post; miCBT: 4.67 [0.55\u00e2\u0080\u00938.78], p = 0.027; RLX: 4.42 [0.38 to 8.46], p = 0.032), whereas no other significant between-group differences were observed. The follow-up analyses revealed significant within-group improvements from baseline to 12-month follow-up in all four primary outcomes for both treatments. However, between-group effects (miCBT vs. RLX) were not significant at follow-up. Conclusion: The miCBT has no better treatment effects compared to RLX in migraine-prophylaxis. Both treatments effectively increase patients' self-efficacy. Trial Registration: German Clinical Trials Register (www.drks.de; DRKS-ID: DRKS00011111). Copyright \u00c2\u00a9 2022 Klan, Gaul, Liesering-Latta, Both, Held, Hennemann and Witth\u00c3\u00b6ft.",
      "authors": [
        "Klan, T.",
        "Gaul, C.",
        "Liesering-Latta, E.",
        "Both, B.",
        "Held, I.",
        "Hennemann, S.",
        "Witth\u00c3\u00b6ft, M."
      ],
      "categories": null,
      "citations": 3,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3389/fneur.2022.852616",
      "keywords": [
        "cognitive-behavioral therapy",
        "behavioral treatment",
        "prevention",
        "relaxation therapy",
        "randomized controlled trial",
        "behavioral therapy",
        "migraine"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Frontiers in Neurology"
      },
      "publication_date": "2022-04-28",
      "selected": false,
      "title": "Efficacy of Cognitive-Behavioral Therapy for the Prophylaxis of Migraine in Adults: A Three-Armed Randomized Controlled Trial",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85130293534&origin=inward"
      ]
    },
    {
      "abstract": "Purpose: The objective of this study was to explore receptiveness of people with poststroke aphasia to receiving transcranial direct current stimulation (tDCS), including preferences for the treatment setting and schedule of tDCS delivery. Method: An online survey was distributed via e-mail, flyers, social media, and online newsletters to reach people with aphasia. Fisher\u00e2\u0080\u0099s exact test examined the relationship of self-reported tDCS receptiveness to demographic, clinical, and other factors. Results: Fifty-seven surveys were returned, and 50 complete surveys were ana-lyzed. Twenty-eight percent of respondents had previously heard of tDCS. Sixty-six percent reported they would receive tDCS if it could help their aphasia, and only 6% reported that they definitely would not. There were statistically sig-nificant relationships between being receptive to tDCS and (a) not currently working, (b) being receptive to speech-language therapy, and (c) greater acceptance of potential temporary risks associated with tDCS. Most individuals (73%) who would consider tDCS were equivalently open to receiving it in the clinic or at home, yet the majority (64%) were open to more frequent sessions at home than in the clinic. Most respondents indicated that they would consider having tDCS \u00e2\u0080\u009cforever if it helped\u00e2\u0080\u009d (clinic: 51%; home: 68%). Conclusions: This is the first study to query individuals with aphasia about their receptiveness to tDCS outside the context of an intervention study. Responses suggest that a large majority of people with poststroke aphasia might be open to receiving tDCS if it can ameliorate their aphasia. Limitations include the small sample size, which does not adequately represent the broader population of people with aphasia, and that the survey did not provide the level of tDCS education crucial to inform shared decision making and person-centered care. However, future work may benefit from considering the practical implications of research designs (e.g., high intensity treatment outside the home) that may not, in application, be widely acceptable to primary stakeholders. Supplemental Material: https://doi.org/10.23641/asha.19611777. \u00c2\u00a9 2022.",
      "authors": [
        "Duncan, E Susan",
        "Donovan, Neila J",
        "Gentimis, Thanos"
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1044/2022_AJSLP-21-00190",
      "keywords": [],
      "number_of_pages": 11,
      "pages": "1383-1393",
      "publication": {
        "category": "Journal",
        "cite_score": 4.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1558-9110",
        "publisher": "American Speech-Language-Hearing Association (ASHA)",
        "sjr": 0.897,
        "snip": 1.457,
        "subject_areas": [
          "Developmental and Educational Psychology",
          "Speech and Hearing",
          "Linguistics and Language",
          "Otorhinolaryngology"
        ],
        "title": "American journal of speech-language pathology"
      },
      "publication_date": "2022-04-21",
      "selected": false,
      "title": "Are People With Poststroke Aphasia Receptive to Transcranial Direct Current Stimulation? A Survey.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85130002078&origin=inward"
      ]
    },
    {
      "abstract": "The primary objective of this study is to explain the factors that influence the continuance intention of accountants to use an accounting information system (AIS) in the context of Jordanian small and medium-sized enterprises (SMEs). Accountants are the main AIS users, and their system acceptance and use are crucial to evaluating the successful implementation of the system. The study conducted a cross-sectional survey on SMEs that have fully implemented an AIS. The proposed framework of the study is based on the extended unified theory of acceptance and use of technology (UTAUT) model and top management support (TMS). The results revealed that the examined vari-ables, namely effort expectancy, performance expectancy and facilitating conditions, have a positive effect on the continuance intention of accountants to use AIS, with TMS having a significant and negative effect on such intention to use. In addition, social influence was found to be significantly related to continuance intention, confirming the need to support technologies such as AIS among SMEs. The study findings contribute to UTAUT theory as they supported the effects of TMS on continuance intention to use and established the study framework measurement accuracy in the context of Jordanian SMEs. \u00c2\u00a9 2022 by the author. Licensee MDPI, Basel, Switzerland.",
      "authors": [
        "Lutfi, A."
      ],
      "categories": null,
      "citations": 41,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3390/economies10040075",
      "keywords": [
        "continuance intention to use",
        "AIS",
        "self-efficacy",
        "top management support",
        "SMEs",
        "unified theory of acceptance and use of technology"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Economies"
      },
      "publication_date": "2022-04-01",
      "selected": false,
      "title": "Factors Influencing the Continuance Intention to Use Accounting Information System in Jordanian SMEs from the Perspectives of UTAUT: Top Management Support and Self-Efficacy as Predictor Factors",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85127788239&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND UNASSIGNED Specific phobias represent the largest category of anxiety disorders. Previous work demonstrated that stimulating the ventromedial prefrontal cortex (vmPFC) with repetitive Transcranial Magnetic Stimulation (rTMS) may improve response to exposure therapy for acrophobia.\nOBJECTIVE UNASSIGNED To examine feasibility of accelerating extinction learning in subjects with spider phobia using intermittent Theta Burst Stimulation (iTBS) rTMS of vmPFC.\nMETHODS UNASSIGNED in vivo n n In total, 17 subjects with spider phobia determined by spider phobia questionnaires [Spider Phobia Questionnaire (SPQ) and Fear of Spiders questionnaire (FSQ)] underwent ratings of fear of spiders as well as behavioral and skin conductance data during a behavioral avoidance test (BAT). Subjects then received a sequential protocol of  spider exposure followed by iTBS for three sessions administered to either active or control treatment sites (vmPFC [ = 8] or vertex [ = 9], respectively), followed 1 week later by repetition of questionnaires and BAT.\nRESULTS UNASSIGNED 2 2 2 p p p All subjects improved significantly regardless of group across both questionnaires (FSQ \u03b7 = 0.43,  = 0.004; SPQ \u03b7 = 0.39,  = 0.008) and skin conductance levels during BAT (Wald \u03c7 = 30.9,  < 0.001). Subjects in the vmPFC group tolerated lower treatment intensity than in the control group, and there was a significant correlation between treatment intensity, BAT subjective distress improvement, and physiologic measures (all \u03c1 > 0.5).\nCONCLUSION UNASSIGNED This proof-of-concept study provides preliminary evidence that a sequential exposure and iTBS over vmPFC is feasible and may have rTMS intensity-dependent effects on treatment outcomes, providing evidence for future areas of study in the use of rTMS for phobias.",
      "authors": [
        "Leuchter, Michael K",
        "Rosenberg, Benjamin M",
        "Schapira, Giuditta",
        "Wong, Nicole R",
        "Leuchter, Andrew F",
        "McGlade, Anastasia L",
        "Krantz, David E",
        "Ginder, Nathaniel D",
        "Lee, Jonathan C",
        "Wilke, Scott A",
        "Tadayonnejad, Reza",
        "Levitt, Jennifer",
        "Marder, Katharine G",
        "Craske, Michelle G",
        "Iacoboni, Marco"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3389/fpsyt.2022.823158",
      "keywords": [
        "N behavioral",
        "N transcranial magnetic stimulation (TMS)",
        "@UI",
        "N neuromodulation",
        "N spider phobia",
        "N phobia",
        "N repetitive transcranial magnetic stimulation (rTMS)",
        "N intermittent theta-burst stimulation (iTBS)",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "823158",
      "publication": {
        "category": "Journal",
        "cite_score": 5.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1664-0640",
        "publisher": "Frontiers Media S.A.",
        "sjr": 1.222,
        "snip": 1.265,
        "subject_areas": [
          "Psychiatry and Mental Health"
        ],
        "title": "Frontiers in psychiatry"
      },
      "publication_date": "2022-03-15",
      "selected": false,
      "title": "Treatment of Spider Phobia Using Repeated Exposures and Adjunctive Repetitive Transcranial Magnetic Stimulation: A Proof-of-Concept Study.",
      "urls": []
    },
    {
      "abstract": "Mindfulness training (MT) promotes the development of one's ability to observe and attend to internal and external experiences with objectivity and nonjudgment with evidence to improve psychological well-being. Real-time functional MRI neurofeedback (rtfMRI-nf) is a noninvasive method of modulating activity of a brain region or circuit. The posterior cingulate cortex (PCC) has been hypothesized to be an important hub instantiating a mindful state. This nonrandomized, single-arm study examined the feasibility and tolerability of training typically developing adolescents to self-regulate the posterior cingulate cortex (PCC) using rtfMRI-nf during MT. Thirty-four adolescents (mean age: 15 years; 14 females) completed the neurofeedback augmented mindfulness training task, including Focus-on-Breath (MT), Describe (self-referential thinking), and Rest conditions, across three neurofeedback and two non-neurofeedback runs (Observe, Transfer). Self-report assessments demonstrated the feasibility and tolerability of the task. Neurofeedback runs differed significantly from non-neurofeedback runs for the Focus-on-Breath versus Describe contrast, characterized by decreased activity in the PCC during the Focus-on-Breath condition (z = -2.38 to -6.27). MT neurofeedback neural representation further involved the medial prefrontal cortex, anterior cingulate cortex, dorsolateral prefrontal cortex, posterior insula, hippocampus, and amygdala. State awareness of physical sensations increased following rtfMRI-nf and was maintained at 1-week follow-up (Cohens' d = 0.69). Findings demonstrate feasibility and tolerability of rtfMRI-nf in healthy adolescents, replicates the role of PCC in MT, and demonstrate a potential neuromodulatory mechanism to leverage and streamline the learning of mindfulness practice. ( ClinicalTrials.gov identifier #NCT04053582; August 12, 2019).",
      "authors": [
        "Kirlic, Namik",
        "Cohen, Zsofia P",
        "Tsuchiyagaito, Aki",
        "Misaki, Masaya",
        "McDermott, Timothy J",
        "Aupperle, Robin L",
        "Stewart, Jennifer L",
        "Singh, Manpreet K",
        "Paulus, Martin P",
        "Bodurka, Jerzy"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3758/s13415-022-00991-4",
      "keywords": [
        "D016428 Journal Article",
        "N Functional magnetic resonance imaging neurofeedback",
        "N Mindfulness",
        "D052061 Research Support, N.I.H., Extramural",
        "D013485 Research Support, Non-U.S. Gov't",
        "D013486 Research Support, U.S. Gov't, Non-P.H.S.",
        "N Functional connectivity",
        "N Posterior cingulate cortex",
        "N Self-regulation",
        "N Adolescents"
      ],
      "number_of_pages": 19,
      "pages": "849-867",
      "publication": {
        "category": "Journal",
        "cite_score": 5.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1531-135X",
        "publisher": "Springer New York",
        "sjr": 1.085,
        "snip": 1.062,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Behavioral Neuroscience"
        ],
        "title": "Cognitive, affective & behavioral neuroscience"
      },
      "publication_date": "2022-03-15",
      "selected": false,
      "title": "Self-regulation of the posterior cingulate cortex with real-time fMRI neurofeedback augmented mindfulness training in healthy adolescents: A nonrandomized feasibility study.",
      "urls": []
    },
    {
      "abstract": "While research to improve memory or counter decay caused by neurodegenerative diseases has a fairly long history, scientific attempts to erase memories are very recent. The use of non-invasive brain stimulation for memory modulation represents a new and promising application for the treatment of certain disorders [such as Post-Traumatic Stress Disorder (PTSD)]. However, numerous ethical issues are related to memory intervention. In particular, the possibility of using forms of non-invasive brain stimulation requires to distinguish treatment interventions from the enhancement of the healthy. Furthermore, a range of important societal and legal concerns arise when manipulating memories. In this short contribution, we address some of the most significant ethical, social, and legal implications surrounding the application of memory-modulation techniques and offer a series of reflections and considerations, which we hope can be of use to guide -and perhaps regulate- their potential, future implementation in society. Copyright \u00c2\u00a9 2022 Farina and Lavazza.",
      "authors": [
        "Farina, M.",
        "Lavazza, A."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3389/fnhum.2022.826862",
      "keywords": [
        "TMS",
        "neuroethics",
        "bio-conservatives",
        "enhancement",
        "bio-liberals"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Frontiers in Human Neuroscience"
      },
      "publication_date": "2022-03-04",
      "selected": false,
      "title": "Memory Modulation Via Non-invasive Brain Stimulation: Status, Perspectives, and Ethical Issues",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85127420215&origin=inward"
      ]
    },
    {
      "abstract": "Autism spectrum disorder (ASD) is a devastating mental disorder in children. Currently, there is no effective treatment for ASD. Transcranial direct current stimulation (tDCS), which is a non-invasive brain stimulation neuromodulation technology, is a promising method for the treatment of ASD. However, the manner in which tDCS changes the electrophysiological process in the brain is still unclear. In this study, we used tDCS to stimulate the dorsolateral prefrontal cortex area of children with ASD (one group received anode tDCS, and the other received sham tDCS) and investigated the changes in evoked EEG signals and behavioral abilities before and after anode and sham stimulations. In addition to tDCS, all patients received conventional rehabilitation treatment. Results show that although conventional treatment can effectively improve the behavioral ability of children with ASD, the use of anode tDCS with conventional rehabilitation can boost this improvement, thus leading to increased treatment efficacy. By analyzing the electroencephalography pre- and post-treatment, we noticed a decrease in the mismatch negativity (MMN) latency and an increase in the MMN amplitude in both groups, these features are considered similar to MMN features from healthy children. However, no statistical difference between the two groups was observed after 4 weeks of treatment. In addition, the MMN features correlate well with the aberrant behavior checklist (ABC) scale, particularly the amplitude of MMN, thus suggesting the feasibility of using MMN features to assess the behavioral ability of children with ASD. Copyright \u00c2\u00a9 2022 Sun, Zhao, Cheng, Tian, Zhao, Du, Zhang and Wang.",
      "authors": [
        "Sun, Changcheng",
        "Zhao, Zhuoyue",
        "Cheng, Longlong",
        "Tian, Rong",
        "Zhao, Wenchang",
        "Du, Jingang",
        "Zhang, Ying",
        "Wang, Chunfang"
      ],
      "categories": null,
      "citations": 4,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.3389/fnins.2022.721987",
      "keywords": [
        "#text",
        "N dorsolateral prefrontal cortex (DLPFC)",
        "N transcranial direct current stimulation (tDCS)",
        "N EEG",
        "N autism spectrum disorder (ASD)",
        "N mismatch negativity (MMN)",
        "@UI"
      ],
      "number_of_pages": null,
      "pages": "721987",
      "publication": {
        "category": "Journal",
        "cite_score": 6.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1662-4548",
        "publisher": "Frontiers Media S.A.",
        "sjr": 1.161,
        "snip": 1.221,
        "subject_areas": [
          "Neuroscience (all)"
        ],
        "title": "Frontiers in neuroscience"
      },
      "publication_date": "2022-02-09",
      "selected": false,
      "title": "Effect of Transcranial Direct Current Stimulation on the Mismatch Negativity Features of Deviated Stimuli in Children With Autism Spectrum Disorder.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85125145317&origin=inward"
      ]
    },
    {
      "abstract": "Neuroimaging studies have suggested that the medial prefrontal cortex (mPFC) is a key brain region for social feedback processing, but previous findings are largely based on correlational approaches. In this study, we use the deep transcranial magnetic stimulation (dTMS) to manipulate mPFC activity, then investigate participants' behavioral performance and event-related potentials (ERPs) during the Social Judgment Paradigm. A between-subject design was applied, such that both the active dTMS group and the sham group consisted of 30 participants. We found that the sham group was more likely to predict that they would be socially accepted (rather than rejected) by peers, but the same was not true in the active group. Additionally, this study is the first one to observe ERP signal changes in response to dTMS manipulation. ERP results show that both the expectation stage and the experience stage of social feedback processing were modulated by dTMS: (1) at the expectation stage, the P1 component was smaller in the active group than the sham group, while the stimulus-preceding negativity showed a stronger differentiating effect between positive and negative prediction in the sham group than the active group; (2) at the experience stage, the sensitivity of the late positive potential to the valence and predictability of social feedback was stronger in the sham group than the active group. These results improve our understanding about the relationship between the mPFC and social feedback processing.",
      "authors": [
        "Zhang, Dandan",
        "Ao, Xiang",
        "Zheng, Zixin",
        "Shen, Junshi",
        "Zhang, Yueyao",
        "Gu, Ruolei"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.neuroimage.2022.118967",
      "keywords": [
        "D016428 Journal Article",
        "N Medial prefrontal cortex",
        "N Deep transcranial magnetic stimulation",
        "N Social judgment paradigm",
        "N Event-related potential",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Social feedback processing"
      ],
      "number_of_pages": null,
      "pages": "118967",
      "publication": {
        "category": "Journal",
        "cite_score": 11.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1095-9572",
        "publisher": "Academic Press Inc.",
        "sjr": 2.512,
        "snip": 1.782,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Neurology"
        ],
        "title": "NeuroImage"
      },
      "publication_date": "2022-02-03",
      "selected": false,
      "title": "Modulating social feedback processing by deep TMS targeting the medial prefrontal cortex: Behavioral and electrophysiological manifestations.",
      "urls": []
    },
    {
      "abstract": "Introduction: Repetitive transcranial magnetic stimulation (rTMS) has been employed worldwide for therapy-resistant depression. The Food and Drug Administration has approved a number of therapeutic devices for treating major depressive disorder; however, no studies have examined the differences in efficacy and acceptability among commercially available stimulation devices. The aim of our study was to compare the efficacy and acceptability of 3 stimulation devices (NeuroStar, MagPro, and Magstim) for depressive disorders. Methods: Our study included 31 randomized shamcontrolled trials of high-frequency rTMS included in the network meta-analysis by Brunoni. We calculated the risk ratio and 95% confidence intervals, comparing each device with sham for the endpoints of response rate, remission rate, and all-cause discontinuation. We then analyzed the differences among the devices in effect size for those endpoints. Results: After determining the effect sizes for the endpoints, we found no statistically significant subgroup differences in the response rates, all-cause discontinuation, or remission rates among the devices (p = 0.12, p = 0.84, and p = 0.07, respectively). Conclusion: Our results suggest similar efficacy and acceptability for the 3 stimulation devices. Future studies need to perform head-to-head comparisons of the efficacy and acceptability of the stimulation devices for treating depression using the same stimulation protocols. \u00c2\u00a9 2021 S. Karger AG, Basel.",
      "authors": [
        "Matsuda, Y.",
        "Yamazaki, R.",
        "Kishi, T.",
        "Iwata, N.",
        "Shigeta, M.",
        "Kito, S."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1159/000517859",
      "keywords": [
        "Meta-analysis",
        "Stimulation device",
        "Repetitive transcranial magnetic stimulation"
      ],
      "number_of_pages": 9,
      "pages": "60-68",
      "publication": {
        "category": "Journal",
        "cite_score": 6.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "0302282X",
        "publisher": "S. Karger AG",
        "sjr": 0.761,
        "snip": 0.922,
        "subject_areas": [
          "Biological Psychiatry",
          "Psychiatry and Mental Health",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Neuropsychobiology"
      },
      "publication_date": "2022-02-01",
      "selected": false,
      "title": "Comparative efficacy and acceptability of 3 repetitive transcranial magnetic stimulation devices for depression: A meta-analysis of randomized, sham-controlled trials",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85112531720&origin=inward"
      ]
    },
    {
      "abstract": "Stroke has been one of the leading causes of disability worldwide and is still a social health issue. Keeping in view the importance of physical rehabilitation of stroke patients, an analytical review has been compiled in which different therapies have been reviewed for their effectiveness, such as functional electric stimulation (FES), noninvasive brain stimulation (NIBS) including transcranial direct current stimulation (t-DCS) and transcranial magnetic stimulation (t-MS), invasive epidural cortical stimulation, virtual reality (VR) rehabilitation, task-oriented therapy, robot-assisted training, tele rehabilitation, and cerebral plasticity for the rehabilitation of upper extremity motor impairment. New therapeutic rehabilitation techniques are also being investigated, such as VR. This literature review mainly focuses on the randomized controlled studies, reviews, and statistical meta-analyses associated with motor rehabilitation after stroke. Moreover, with the increasing prevalence rate and the adverse socio-economic consequences of stroke, a statistical analysis covering its economic factors such as treatment, medication and post-stroke care services, and risk factors (modifiable and non-modifiable) have also been discussed. This review suggests that if the prevalence rate of the disease remains persistent, a considerable increase in the stroke population is expected by 2025, causing a substantial economic burden on society, as the survival rate of stroke is high compared to other diseases. Compared to all the other therapies, VR has now emerged as the modern approach towards rehabilitation motor activity of impaired limbs. A range of randomized controlled studies and experimental trials were reviewed to analyse the effectiveness of VR as a rehabilitative treatment with considerable satisfactory results. However, more clinical controlled trials are required to establish a strong evidence base for VR to be widely accepted as a preferred rehabilitation therapy for stroke.",
      "authors": [
        "Anwer, Saba",
        "Waris, Asim",
        "Gilani, Syed Omer",
        "Iqbal, Javaid",
        "Shaikh, Nusratnaaz",
        "Pujari, Amit N",
        "Niazi, Imran Khan"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3390/healthcare10020190",
      "keywords": [
        "N risk factors",
        "N tele rehabilitation",
        "D016428 Journal Article",
        "N non-modifiable",
        "N epidural",
        "D016454 Review",
        "N stroke",
        "N virtual reality (VR)",
        "N modifiable",
        "N electric stimulation",
        "N NIBS",
        "N rehabilitation"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 2.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2227-9032",
        "publisher": "MDPI AG",
        "sjr": 0.55,
        "snip": 0.873,
        "subject_areas": [
          "Leadership and Management",
          "Health Informatics",
          "Health Information Management",
          "Health Policy"
        ],
        "title": "Healthcare (Basel, Switzerland)"
      },
      "publication_date": "2022-01-19",
      "selected": false,
      "title": "Rehabilitation of Upper Limb Motor Impairment in Stroke: A Narrative Review on the Prevalence, Risk Factors, and Economic Statistics of Stroke and State of the Art Therapies.",
      "urls": []
    },
    {
      "abstract": "The aim of the study was a comparative analysis of subjective assessments and audiological parameters of patients with hearing loss obtained before and after the course of transcranial electrical stimulation (TES). The study group included 99 patients (45 men and 54 women) with chronic mono- (16%) and bilateral (76%) sensorineural hearing loss (SNHL) aged 20 to 85 years. Groups of young and middle age (20-59 years old) amounted to 37 people; elderly (60-74 years old) - 48 and senile (75-90 years old) - 14 people. The observation included: anamnesis, ENT survey, tone threshold audiometry, impedancemetry, and questioning. All patients underwent a course of 10 TES procedures using the \u00abTransair-7\u00bb device. The data indicated an improvement in subjective assessments regarding auditory perception in 54%, speech intelligibility in 53%, tinnitus in 24% and general well-being in 36% of patients in the study group. The distribution of hearing thresholds in the region of speech frequencies before and after the course also turned out to be significantly different (p<0,01). At the same time, gender and age-specific features of the effect of TES on hearing and general well-being were revealed, the most pronounced in senile patients who showed minimal positive dynamics. In general, taking into account age restrictions, the results confirm the feasibility of using TES in SNHL, even outside the combined (with audio loading) stimulation.",
      "authors": [
        "Golovanova, L E",
        "Zyuzina, M N",
        "Belyanina, D A",
        "Ogorodnikova, E A"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": null,
      "keywords": [
        "D004740 English Abstract",
        "N tone threshold audiometry",
        "N gender and age characteristics",
        "N sensorineural hearing loss",
        "D016428 Journal Article",
        "N transcranial electrical stimulation",
        "N subjective assessments"
      ],
      "number_of_pages": 8,
      "pages": "502-509",
      "publication": {
        "category": "Journal",
        "cite_score": 0.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1561-9125",
        "publisher": "Eskulap",
        "sjr": 0.131,
        "snip": 0.873,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "Advances in gerontology = Uspekhi gerontologii"
      },
      "publication_date": "2022-01-01",
      "selected": false,
      "title": "[Transcranial electrical stimulation of audiology patients of different ages.].",
      "urls": []
    },
    {
      "abstract": "Since the first statement of the German Society of Oto-Rhino-Laryngology, hypoglossal nerve stimulation (HNS) is meanwhile an established treatment option for obstructive sleep apnea (OSA). There are three HNS systems available in Germany which differ in their technical details of the underlying comparable basic principle. For the unilateral HNS with respiratory sensing, several comparative studies, high-volume register analysis and long-term reports exist. The continuous HNS without respiratory sensing does not require a sleep endoscopy for indication. For the bilateral continuous HNS as the single partially implantable device, a feasibility study exists. For indication, the assessment of positive airway pressure failure by sleep medicine is crucial, and the decision for HNS should be made in discussion of other treatment options for at least moderate OSA. The implantation center holds primarily responsibility among the interdisciplinary sleep team and is primary contact for the patient in problems. This depicts why structural processes are required to secure outcome quality and minimize the complications. The aftercare of HNS patients can be provided interdisciplinary and by different medical institutions, whereat, minimal reporting standards to document outcome and usage are recommended. \u00c2\u00a9 2021, The Author(s).",
      "authors": [
        "Steffen, A.",
        "Heiser, C.",
        "Galetke, W.",
        "Herkenrath, S.-D.",
        "Maurer, J.T.",
        "G\u00c3\u00bcnther, E.",
        "Stuck, B.A.",
        "Woehrle, H.",
        "L\u00c3\u00b6hler, J.",
        "Randerath, W."
      ],
      "categories": null,
      "citations": 9,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1007/s00405-021-06902-6",
      "keywords": [
        "DISE",
        "Sleep endoscopy",
        "Neurostimulation",
        "Obstructive sleep apnea",
        "Hypoglossal nerve stimulation",
        "CPAP failure"
      ],
      "number_of_pages": 6,
      "pages": "61-66",
      "publication": {
        "category": "Journal",
        "cite_score": 5.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "09374477",
        "publisher": "Springer Verlag",
        "sjr": 0.857,
        "snip": 1.437,
        "subject_areas": [
          "Otorhinolaryngology"
        ],
        "title": "European Archives of Oto-Rhino-Laryngology"
      },
      "publication_date": "2022-01-01",
      "selected": false,
      "title": "Hypoglossal nerve stimulation for obstructive sleep apnea: updated position paper of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85108260425&origin=inward"
      ]
    },
    {
      "abstract": "Multiple mental disorders have been associated with dysregulation of precise brain processes. However, few therapeutic approaches can correct such specific patterns of brain activity. Since the late 1960s and early 1970s, many researchers have hoped that this feat could be achieved by closed-loop brain imaging approaches, such as neurofeedback, that aim to modulate brain activity directly. However, neurofeedback never gained mainstream acceptance in mental health, in part due to methodological considerations. In this review, we argue that, when contemporary methodological guidelines are followed, neurofeedback is one of the few intervention methods in psychology that can be assessed in double-blind placebo-controlled trials. Furthermore, using new advances in machine learning and statistics, it is now possible to target very precise patterns of brain activity for therapeutic purposes. We review the recent literature in functional magnetic resonance imaging neurofeedback and discuss current and future applications to mental health. Copyright \u00c2\u00a9 2022 by Annual Reviews. All rights reserved.",
      "authors": [
        "Taschereau-Dumouchel, V.",
        "Cushing, C.A.",
        "Lau, H."
      ],
      "categories": null,
      "citations": 10,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1146/annurev-clinpsy-072220-014550",
      "keywords": [
        "decoded neurofeedback",
        "real-time brain imaging",
        "neurofeedback",
        "machine learning",
        "functional magnetic resonance imaging"
      ],
      "number_of_pages": 10,
      "pages": "125-134",
      "publication": {
        "category": "Book",
        "cite_score": 31.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "15485943",
        "publisher": "Annual Reviews Inc.",
        "sjr": 6.744,
        "snip": 6.889,
        "subject_areas": [
          "Psychiatry and Mental Health",
          "Clinical Psychology"
        ],
        "title": "Annual Review of Clinical Psychology"
      },
      "publication_date": "2022-01-01",
      "selected": false,
      "title": "Real-Time Functional MRI in the Treatment of Mental Health Disorders",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85130000950&origin=inward"
      ]
    },
    {
      "abstract": "This study focuses on the acceptance intent of wearable devices for depression treatment. Transcranial Direct Current Simulation (TDCS) technology for depression treatment has shown a sharp increase in the number of depression patients in recent years and a growing interest in them. This study combines product and user characteristics to create a TAM (Technical Acceptance Model) based model for depression therapy wearable. Independent variables include innovation, social impact, mobility, perceived cost, proof of result variables, and dependent variables include perceived usefulness, perceived ease, attitude, and behavior intention. Based on 386 surveys, this study analyzes the degree of influence of independent variables using SmartPLS 3.0. Analysis shows that innovation, mobility, proof of results affect perceived usefulness, perceived ease, attitude, behavior intention, social impact, and perceived cost do not affect perceived edge. There-fore, since ease of use of the product is not significantly affected by social impact or cost, developing wearable technologies will need to focus primarily on product innovation and mobility, which will be a good proactive study of developing wearable products to measure various diseases or exercise, including depression. \u00c2\u00a9 2022, ICIC International.",
      "authors": [
        "Xing, Y.Y.",
        "Kim, M.",
        "Park, S.-Y."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.24507/icicelb.13.01.63",
      "keywords": [
        "TAM model",
        "Acceptance intention",
        "Attitude",
        "Behavior intention",
        "Wearable device",
        "Depression",
        "Treat-ment"
      ],
      "number_of_pages": 9,
      "pages": "63-71",
      "publication": {
        "category": "Journal",
        "cite_score": 1.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "21852766",
        "publisher": "ICIC Express Letters Office",
        "sjr": 0.23,
        "snip": 0.32,
        "subject_areas": [
          "Computer Science (all)"
        ],
        "title": "ICIC Express Letters, Part B: Applications"
      },
      "publication_date": "2022-01-01",
      "selected": false,
      "title": "ACCEPTANCE INTENTION OF WEARABLES FOR TREATING DEPRESSION",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85123103806&origin=inward"
      ]
    },
    {
      "abstract": "Video games are a promising area of intervention for children diagnosed with Autism Spectrum Disorders (ASD). However, reviews on this topic are scarce. This review on studies exploring video games for the treatment of ASD followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, and its protocol was registered in PROSPERO. PubMed, PsycInfo, Embase, WebOfScience and clinicaltrials.gov databases were searched. Twenty-four articles were included in the review. Video game-based interventions were effective for alleviating ASD symptoms, albeit with small effect sizes. High rates of acceptability and adherence to treatment were obtained. Conclusion: Video games are a promising area for improving the treatment of children with ASD. Exploring commercial video games is one of the lines for future research. \u00c2\u00a9 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.",
      "authors": [
        "Jim\u00c3\u00a9nez-Mu\u00c3\u00b1oz, L.",
        "Pe\u00c3\u00b1uelas-Calvo, I.",
        "Calvo-Rivera, P.",
        "D\u00c3\u00adaz-Oliv\u00c3\u00a1n, I.",
        "Moreno, M.",
        "Baca-Garc\u00c3\u00ada, E.",
        "Porras-Segovia, A."
      ],
      "categories": null,
      "citations": 18,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1007/s10803-021-04934-9",
      "keywords": [
        "Cognition",
        "Autism Spectrum Disorder",
        "Video games",
        "ASD",
        "EHealth",
        "Training",
        "Children"
      ],
      "number_of_pages": 20,
      "pages": "169-188",
      "publication": {
        "category": "Journal",
        "cite_score": 7.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "01623257",
        "publisher": "Springer New York",
        "sjr": 1.196,
        "snip": 1.863,
        "subject_areas": [
          "Developmental and Educational Psychology"
        ],
        "title": "Journal of Autism and Developmental Disorders"
      },
      "publication_date": "2022-01-01",
      "selected": false,
      "title": "Video Games for the Treatment of Autism Spectrum Disorder: A Systematic Review",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85102083595&origin=inward"
      ]
    },
    {
      "abstract": "Patients with autism spectrum disorder (ASD) display distinctive neurophysiological characteristics associated with significant cognitive, emotional, and behavioral symptoms. Transcranial direct current stimulation (tDCS) applied to the frontal or temporoparietal lobes has demonstrated potential to reduce the severity of ASD-related symptoms. Recently, the cerebellum has been identified as a brain area involved in ASD pathophysiology. In this open-label pilot study, seven ASD patients aged between 9 and 13 years underwent 20 daily sessions of 20 min cathodal stimulation of the right cerebellar lobe. At the end of the treatment, the Aberrant Behavior Checklist (ABC) scores showed a 25% mean reduction in global severity of symptoms, with a more pronounced reduction in the \u00e2\u0080\u009csocial withdrawal and lethargy\u00e2\u0080\u009d (\u00e2\u0088\u009235%), \u00e2\u0080\u009chyperactivity and noncompliance\u00e2\u0080\u009d (\u00e2\u0088\u009226%), and \u00e2\u0080\u009cirritability, agitation, and crying\u00e2\u0080\u009d (\u00e2\u0088\u009225%) subscales. Minor and no improvement were observed in the \u00e2\u0080\u009cstereo-typic behavior\u00e2\u0080\u009d (\u00e2\u0088\u009218%) and \u00e2\u0080\u009cinappropriate speech\u00e2\u0080\u009d (\u00e2\u0088\u00920%) subscales, respectively. Improvements were not detected in the two patients who were taking psychotropic drugs during the study. Clinical response showed a symptom-specific time course. Quality of sleep and mood improved earlier than hyperactivity and social withdrawal. The treatment was generally accepted by patients and well tolerated. No serious adverse events were reported. Stimulation also appeared to markedly reduce the severity of tics in a patient with comorbid tic disorder and led to the disappearance of a frontal epileptogenic focus in another patient with a history of seizures. In conclusion, cerebellar tDCS is safe, feasible, and potentially effective in the treatment of ASD symptoms among children. Strategies to improve recruitment and retention are discussed. \u00c2\u00a9 2021 by the authors. Licensee MDPI, Basel, Switzerland.",
      "authors": [
        "D'Urso, Giordano",
        "Toscano, Elena",
        "Sanges, Veronica",
        "Sauvaget, Anne",
        "Sheffer, Christine E",
        "Riccio, Maria Pia",
        "Ferrucci, Roberta",
        "Iasevoli, Felice",
        "Priori, Alberto",
        "Bravaccio, Carmela",
        "de Bartolomeis, Andrea"
      ],
      "categories": null,
      "citations": 8,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.3390/jcm11010143",
      "keywords": [
        "N epilepsy",
        "N tic disorder",
        "@UI",
        "N tDCS",
        "N autism spectrum disorder (ASD)",
        "#text",
        "N cerebellum"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 5.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2077-0383",
        "publisher": "MDPI AG",
        "sjr": 0.935,
        "snip": 1.179,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "Journal of clinical medicine"
      },
      "publication_date": "2021-12-28",
      "selected": true,
      "title": "Cerebellar Transcranial Direct Current Stimulation in Children with Autism Spectrum Disorder: A Pilot Study on Efficacy, Feasibility, Safety, and Unexpected Outcomes in Tic Disorder and Epilepsy.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85121686460&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND To apply transcranial electrical stimulation (tES) to the motor cortex, motor hotspots are generally identified using motor evoked potentials by transcranial magnetic stimulation (TMS). The objective of this study is to validate the feasibility of a novel electroencephalography (EEG)-based motor-hotspot-identification approach using a machine learning technique as a potential alternative to TMS.\nMETHODS EEG data were measured using 63 channels from thirty subjects as they performed a simple finger tapping task. Power spectral densities of the EEG data were extracted from six frequency bands (delta, theta, alpha, beta, gamma, and full) and were independently used to train and test an artificial neural network for motor hotspot identification. The 3D coordinate information of individual motor hotspots identified by TMS were quantitatively compared with those estimated by our EEG-based motor-hotspot-identification approach to assess its feasibility.\nRESULTS The minimum mean error distance between the motor hotspot locations identified by TMS and our proposed motor-hotspot-identification approach was 0.22\u2009\u00b1\u20090.03\u00a0cm, demonstrating the proof-of-concept of our proposed EEG-based approach. A mean error distance of 1.32\u2009\u00b1\u20090.15\u00a0cm was measured when using only nine channels attached to the middle of the motor cortex, showing the possibility of practically using the proposed motor-hotspot-identification approach based on a relatively small number of EEG channels.\nCONCLUSION We demonstrated the feasibility of our novel EEG-based motor-hotspot-identification method. It is expected that our approach can be used as an alternative to TMS for motor hotspot identification. In particular, its usability would significantly increase when using a recently developed portable tES device integrated with an EEG device.",
      "authors": [
        "Choi, Ga-Young",
        "Han, Chang-Hee",
        "Lee, Hyung-Tak",
        "Paik, Nam-Jong",
        "Kim, Won-Seok",
        "Hwang, Han-Jeong"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1186/s12984-021-00972-7",
      "keywords": [
        "N Machine learning",
        "N Electroencephalography",
        "D016428 Journal Article",
        "N Transcranial electrical stimulation",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Motor hotspot",
        "N Artificial neural-network"
      ],
      "number_of_pages": null,
      "pages": "176",
      "publication": {
        "category": "Journal",
        "cite_score": 8.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1743-0003",
        "publisher": "BioMed Central Ltd.",
        "sjr": 1.134,
        "snip": 1.924,
        "subject_areas": [
          "Rehabilitation",
          "Health Informatics"
        ],
        "title": "Journal of neuroengineering and rehabilitation"
      },
      "publication_date": "2021-12-20",
      "selected": false,
      "title": "An artificial neural-network approach to identify motor hotspot for upper-limb based on electroencephalography: a proof-of-concept study.",
      "urls": []
    },
    {
      "abstract": "Specific alterations in electroencephalography (EEG)-based brain activity have recently been linked to binge-eating disorder (BED), generating interest in treatment options targeting these neuronal processes. This randomized-controlled pilot study examined the effectiveness and feasibility of two EEG neurofeedback paradigms in the reduction of binge eating, eating disorder and general psychopathology, executive functioning, and EEG activity. Adults with BED and overweight (N = 39) were randomly assigned to either a food-specific EEG neurofeedback paradigm, aiming at reducing fronto-central beta activity and enhancing theta activity after viewing highly palatable food pictures, or a general EEG neurofeedback paradigm training the regulation of slow cortical potentials. In both conditions, the study design included a waiting period of 6\u00c2 weeks, followed by 6\u00c2 weeks EEG neurofeedback (10 sessions \u00c3  30\u00c2 min) and a 3-month follow-up period. Both EEG neurofeedback paradigms significantly reduced objective binge-eating episodes, global eating disorder psychopathology, and food craving. Approximately one third of participants achieved abstinence from objective binge-eating episodes after treatment without any differences between treatments. These results were stable at 3-month follow-up. Among six measured executive functions, only decision making improved at posttreatment in both paradigms, and cognitive flexibility was significantly improved after food-specific neurofeedback only. Both EEG neurofeedback paradigms were equally successful in reducing relative beta and enhancing relative theta power over fronto-central regions. The results highlight EEG neurofeedback as a promising treatment option for individuals with BED. Future studies in larger samples are needed to determine efficacy and treatment mechanisms. \u00c2\u00a9 2021, The Author(s).",
      "authors": [
        "Blume, Marie",
        "Schmidt, Ricarda",
        "Schmidt, Jennifer",
        "Martin, Alexandra",
        "Hilbert, Anja"
      ],
      "categories": null,
      "citations": 9,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1007/s13311-021-01149-9",
      "keywords": [
        "N Beta/theta training",
        "D016428 Journal Article",
        "D013485 Research Support, Non-U.S. Gov't",
        "D016449 Randomized Controlled Trial",
        "N SCP training",
        "N Binge-eating disorder",
        "N Eating disorders",
        "N EEG neurofeedback"
      ],
      "number_of_pages": 14,
      "pages": "352-365",
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1878-7479",
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics"
      },
      "publication_date": "2021-12-20",
      "selected": false,
      "title": "EEG Neurofeedback in the Treatment of Adults with Binge-Eating Disorder: a Randomized Controlled Pilot Study.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85121421806&origin=inward"
      ]
    },
    {
      "abstract": "Background: Autism spectrum disorder (ASD) is associated with anxiety and sleep prob-lems. We investigated transdermal electrical neuromodulation (TEN) of the cervical nerves in the neck as a safe, effective, comfortable and non-pharmacological therapy for decreasing anxiety and enhancing sleep quality in ASD. Methods: In this blinded, sham-controlled study, seven adolescents and young adults with high-functioning ASD underwent five consecutive treatment days, one day of the sham followed by four days of subthreshold TEN for 20 min. Anxiety-provoking cognitive tasks were performed after the sham/TEN. Measures of autonomic nervous system activity, includ-ing saliva \u00ce\u00b1-amylase and cortisol, electrodermal activity, and heart rate variability, were collected from six participants. Results: Self-rated and caretaker-rated measures of anxiety were significantly improved with TEN treatment as compared to the sham, with effect sizes ranging from medium to large depending on the rating scale. Sleep scores from caretaker questionnaires also improved, but not significantly. Performance on two of the three anxiety-provoking cognitive tasks and heart rate variability significantly improved with TEN stimulation as compared to the sham. Four of the seven (57%) participants were responders, defined as a \u00e2\u0089\u00a5 30% improvement in self-reported anxiety. Salivary \u00ce\u00b1-amylase decreased with more TEN sessions and decreased from the beginning to the end of the session on TEN days for responders. TEN was well-tolerated without significant adverse events. Conclusions: This study provides preliminary evidence that TEN is well-tolerated in individuals with ASD and can improve anxiety. \u00c2\u00a9 2021 by the authors. Licensee MDPI, Basel, Switzerland.",
      "authors": [
        "Foldes, Stephen T",
        "Jensen, Amanda R",
        "Jacobson, Austin",
        "Vassall, Sarah",
        "Foldes, Emily",
        "Guthery, Ann",
        "Brown, Danni",
        "Levine, Todd",
        "Tyler, William James",
        "Frye, Richard E"
      ],
      "categories": null,
      "citations": 3,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.3390/jpm11121307",
      "keywords": [
        "N \u03b1-amylase",
        "N transdermal electrical neuromodulation",
        "N anxiety",
        "N neurostimulation",
        "N autism spectrum disorder",
        "#text",
        "N cortisol",
        "N neuromodulation",
        "N sleep anxiety",
        "N heart rate variability",
        "@UI"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 2.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2075-4426",
        "publisher": "Multidisciplinary Digital Publishing Institute (MDPI)",
        "sjr": 0.665,
        "snip": 0.729,
        "subject_areas": [
          "Medicine (miscellaneous)"
        ],
        "title": "Journal of personalized medicine"
      },
      "publication_date": "2021-12-06",
      "selected": true,
      "title": "Transdermal Electrical Neuromodulation for Anxiety and Sleep Problems in High-Functioning Autism Spectrum Disorder: Feasibility and Preliminary Findings.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85121614038&origin=inward"
      ]
    },
    {
      "abstract": "Background Overgeneralised self-blame and worthlessness are key symptoms of major depressive disorder (MDD) and have previously been associated with self-blame-selective changes in connectivity between right superior anterior temporal lobe (rSATL) and subgenual frontal cortices. Another study showed that remitted MDD patients were able to modulate this neural signature using functional magnetic resonance imaging (fMRI) neurofeedback training, thereby increasing their self-esteem. The feasibility and potential of using this approach in symptomatic MDD were unknown. Method This single-blind pre-registered randomised controlled pilot trial probed a novel self-guided psychological intervention with and without additional rSATL-posterior subgenual cortex (BA25) fMRI neurofeedback, targeting self-blaming emotions in people with insufficiently recovered MDD and early treatment-resistance (n = 43, n = 35 completers). Participants completed three weekly self-guided sessions to rebalance self-blaming biases. Results As predicted, neurofeedback led to a training-induced reduction in rSATL-BA25 connectivity for self-blame v. other-blame. Both interventions were safe and resulted in a 46% reduction on the Beck Depression Inventory-II, our primary outcome, with no group differences. Secondary analyses, however, revealed that patients without DSM-5-defined anxious distress showed a superior response to neurofeedback compared with the psychological intervention, and the opposite pattern in anxious MDD. As predicted, symptom remission was associated with increases in self-esteem and this correlated with the frequency with which participants employed the psychological strategies in daily life. Conclusions These findings suggest that self-blame-rebalance neurofeedback may be superior over a solely psychological intervention in non-anxious MDD, although further confirmatory studies are needed. Simple self-guided strategies tackling self-blame were beneficial, but need to be compared against treatment-as-usual in further trials. https://doi.org/10.1186/ISRCTN10526888 Copyright \u00c2\u00a9 The King's College London, 2021. Published by Cambridge University Press.",
      "authors": [
        "Jaeckle, Tanja",
        "Williams, Steven C R",
        "Barker, Gareth J",
        "Basilio, Rodrigo",
        "Carr, Ewan",
        "Goldsmith, Kimberley",
        "Colasanti, Alessandro",
        "Giampietro, Vincent",
        "Cleare, Anthony",
        "Young, Allan H",
        "Moll, Jorge",
        "Zahn, Roland"
      ],
      "categories": null,
      "citations": 4,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1017/S0033291721004797",
      "keywords": [
        "N major depressive disorder",
        "D016428 Journal Article",
        "N anterior temporal lobe",
        "N subgenual cingulate cortex",
        "N Brodmann Area 25",
        "N social cognition",
        "N neurofeedback",
        "D016449 Randomized Controlled Trial",
        "N real-time fMRI",
        "N guilt",
        "N Anger",
        "N psychotherapy"
      ],
      "number_of_pages": 11,
      "pages": "2831-2841",
      "publication": {
        "category": "Journal",
        "cite_score": 13.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1469-8978",
        "publisher": "Cambridge University Press",
        "sjr": 2.465,
        "snip": 2.136,
        "subject_areas": [
          "Applied Psychology",
          "Psychiatry and Mental Health"
        ],
        "title": "Psychological medicine"
      },
      "publication_date": "2021-12-02",
      "selected": false,
      "title": "Self-blame in major depression: a randomised pilot trial comparing fMRI neurofeedback with self-guided psychological strategies.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85120653398&origin=inward"
      ]
    },
    {
      "abstract": "Treatment resistant depression (TRD) is a serious public health problem. It is estimated that around 20- 40% of patients with a major depressive episode (whether monopolar or bipolar) do not exhibit clinical response to the current treatment with antidepressants, that is at least 50% decline in the symptoms scale. Furthermore, about half of the patients with symptom amelioration present residual symptoms which continue to negatively affect their functioning and increase the chance of relapse. Therefore, only 20-40% of patients (36.8% in STAR*D)1 who receive therapy for a major depressive episode for the first time exhibit remission (i.e., at least 70% decrease in symptom severity or HAMD score \u00e2\u0089\u00a47/MADRS score \u00e2\u0089\u00a410)2 - which is the goal of current treatments. Even when remission is achieved, though, there is often a long way to recovery and to the patient's return to the prior state of occupational and social functioning. Moreover, long-term medical treatment is needed in order to achieve and maintain the above.3 TRD is characterized by high rates of comorbidity (hypertension, diabetes mellitus, heart failure), doubles the rates of hospitalizations and lengthens the time of hospitalization by 36%, while the percentage of suicidal incidents is seven times higher in TRD compared to cases of treatment-responsive depression.4 TRD exhibits higher rates of mortality than treatment-responsive depression, with all-cause mortality rate being higher5 by 29-35% and similar to that of older by 13 years, non-depressed individuals. Despite its common occurrence and the fact that TRD constitutes an important issue in the treatment of major depression disorder (MDD), experts still disagree on the exact meaning of the term. The most widely accepted and used term of TRD refers to treatment resistance as treatment with at least two different antidepressants (of the same or different classes), administered in the right doses and for an adequate amount of time, with verified patient compliance to treatment which, however, fails to produce significant clinical results.6 Other terms have also been used as an alternative, for example Difficult to Treat Depression in order to avoid nihilism - something often seen in these cases;7 Drug Resistant Depression so as to determine the exact kind of resistance and also to underline the need for combination therapy with intervention such as psychotherapy and ECT; Multiple Therapy Resistant MDD; Pernicious Depression8 etc. Treatment of TRD is a challenge for every clinician. After excluding the possibility of pseudo-resistance due to misdiagnosis, insufficient therapeutic regimen, comorbid disorders, such as anxiety disorders, eating disorders, personality disorders, substance abuse/addiction, PTSD, non-compliance to treatment, non-identified organicity and chronic stressors, the therapeutic methods used include: optimization, watchful waiting, past response, combination treatment, add-on treatments, ECT, TMS, vagus nerve stimulation, phototherapy, psychotherapy, neurosurgery. All the above are thoroughly discussed in this Supplement issue of Psychiatriki.9.",
      "authors": [
        "Touloumis, C."
      ],
      "categories": null,
      "citations": 22,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.22365/jpsych.2021.046",
      "keywords": [],
      "number_of_pages": 4,
      "pages": "11-14",
      "publication": {
        "category": "Journal",
        "cite_score": 1.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "11052333",
        "publisher": "Hellenike Psychiatrike Hetaireia",
        "sjr": 0.411,
        "snip": 1.863,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "Psychiatrike = Psychiatriki"
      },
      "publication_date": "2021-12-01",
      "selected": false,
      "title": "The burden and the challenge of treatment-resistant depression",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85123270187&origin=inward"
      ]
    },
    {
      "abstract": "Young adults with intellectual and developmental disabilities (IDDs) are at an increased risk of developing mental health disorders. Mindfulness may be one strategy that can help support the mental health needs of this particular population; however, those with (IDDs) may need additional support in cultivating the practice. The purpose of this study was to investigate the use of a wearable device designed to provide neurofeedback to help promote state mindfulness in young adults with (IDDs). Additionally, attention and affect mechanisms were examined, as well as the social validity of using the wearable device. Using an A-B-A-B single-subject study design, five (age range = 18\u00e2\u0080\u009325) students completed 20 sessions that consisted of listening and not listening to neurofeedback. Results provide some support for the positive effect of neurofeedback on state mindfulness, paying attention to the breath, and positive affect. All five students reported acceptability of using the device. \u00c2\u00a9 The Author(s) 2020.",
      "authors": [
        "McMahon, A.K.",
        "Cox, A.E.",
        "Miller, D.E."
      ],
      "categories": null,
      "citations": 2,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1177/0162643420924191",
      "keywords": [
        "attention",
        "wearable devices",
        "meditation",
        "affect",
        "self-regulation"
      ],
      "number_of_pages": 13,
      "pages": "284-296",
      "publication": {
        "category": "Journal",
        "cite_score": 3.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "01626434",
        "publisher": "SAGE Publications Inc.",
        "sjr": 0.557,
        "snip": 1.415,
        "subject_areas": [
          "Education",
          "Computer Science Applications"
        ],
        "title": "Journal of Special Education Technology"
      },
      "publication_date": "2021-12-01",
      "selected": false,
      "title": "Supporting Mindfulness With Technology in Students With Intellectual and Developmental Disabilities",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85084415126&origin=inward"
      ]
    },
    {
      "abstract": "Background: Chronic pain is correlated with alterations in brain structure and function. The selection process for the ideal candidate for spinal cord stimulation (SCS) therapy is based on functional variables analysis and pain evaluation scores. In addition to the difficulties involved in the initial selection of patients and the predictive analysis of the trial phase, the large rate of explants is one of the most important concerns in the analysis of the suitability of implanted candidates. Objective: To investigate the usefulness of imaging biomarkers, functional connectivity (FC) and volumetry of the whole brain in patients with Failed back surgery syndrome (FBSS) and to create a clinical patient-based decision support system (CDSS) combining neuroimaging and clinical data for predicting the effectiveness of neurostimulation therapy after a trial phase. Study Design: A prospective, consecutive, observational, single center study. Setting: The Multidisciplinary Pain Management Department of the General University Hospital in Valencia, Spain. Methods: A prospective, consecutive, and observational single-center study. Using Resting-state functional magnetic resonance imaging (rs-fMRI) and Region of interest (ROI) to ROI analysis, we compared the functional connectivity between regions to detect differences in FC and volume changes. Basal magnetic resonance images were obtained in a 1.5T system and clinical variables were collected twice, at the basal condition and at 6-months post-SCS implant. We also conducted a seed-to-voxel analysis with 9 items as seed-areas characterizing the functional connectivity networks. A decreased in 10 units in the Pain Detect Questionnaire (PD-Q) score was established to define the subgroup of Responders Group (R-G) to neurostimulation therapy. The clinical variables collected and the imaging biomarkers obtained (FC and volumes) were tested on a set of 6 machine learning approaches in an effort to find the best classifier system for predicting the effectiveness of the neurostimulator. Results: Twenty-four patients were analyzed and only seven were classified in the R-G. Volumetric differences were found in the left putamen, F = 34.06, P = 0.02. Four pairwise brain areas showed statistical differences in the rs-fMRI including the right insular cortex. Linear Discriminant Analysis showed the best performance for building the CDSS combining clinical variables and significant imaging biomarkers, the prediction increased diagnostic accuracy in the R-G patients from 29% in current practice to 96% of long-term success. Conclusion: These findings confirm a major role of the left putamen and the four pairs of brain regions in FBBS patients and suggest that a CDSS would be able to select patients susceptible to benefitting from SCS therapy adding imaging biomarkers. \u00c2\u00a9 2021, American Society of Interventional Pain Physicians. All rights reserved.",
      "authors": [
        "De Andres, J.",
        "Ten-Esteve, A.",
        "Harutyunyan, A.",
        "Romero-Garcia, C.S.",
        "Fabregat-Cid, G.",
        "Asensio-Samper, J.M.",
        "Alberich-Bayarri, A.",
        "Marti-Bonmati, L."
      ],
      "categories": null,
      "citations": 5,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": null,
      "keywords": [
        "spinal cord stimulation",
        "Chronic pain",
        "neuroimaging",
        "rs-fMRI",
        "imaging biomarker",
        "supraspinal mechanisms",
        "machine learning",
        "structural imaging",
        "failed back surgery syndrome"
      ],
      "number_of_pages": null,
      "pages": "E1279-E1290",
      "publication": {
        "category": "Journal",
        "cite_score": 5.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "15333159",
        "publisher": "Association of Pain Management Anesthesiologists",
        "sjr": 0.824,
        "snip": 1.353,
        "subject_areas": [
          "Anesthesiology and Pain Medicine"
        ],
        "title": "Pain Physician"
      },
      "publication_date": "2021-12-01",
      "selected": false,
      "title": "Predictive Clinical Decision Support System Using Machine Learning and Imaging Biomarkers in Patients With Neurostimulation Therapy: A Pilot Study",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85121993776&origin=inward"
      ]
    },
    {
      "abstract": "In this case, 62 university students participated in the study, in which a between-subjects design was adopted. Participants were also given the behavioral approach system (BAS) and behavioral inhibition system (BIS) scales. Participants had to read a list of 60 sentences with interpersonal and neutral content: 20 approach (\"Pedro accepted Rosa in Whatsapp\"), 20 avoidance (\"Pedro Blocked Rosa in Whatsapp\") and 20 neutral (\"Marta thought about the causes of the problem\"). After reading them, they were subjected to 20 min of transcranial direct current stimulation (tDCS) in one of the two conditions: anodal (31) or sham (31). After tDCS, they had to read other list of 60 sentences matched in approach, avoidance and neutral contents with the former list. We found significant improvement in reading speed after anodal stimulation for social and neutral sentences. Regarding affective traits, we found that anodal stimulation benefitted reading speed in low-BIS and low-BAS participants and had no effect in either high BAS or high BIS participants. In addition, tDCS improvement in reading speed was significantly lower in avoidance sentences in low-BIS (avoidance) participants. We discuss these results at the light of previous research and highlight the importance of approach and avoidance traits as moderators of tDCS effects.",
      "authors": [
        "Reyes, Cristian",
        "Padr\u00f3n, Iv\u00e1n",
        "Nila Yagual, Sara",
        "Marrero, Hip\u00f3lito"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3390/brainsci11111464",
      "keywords": [
        "N approach/avoidance intentionality",
        "@UI",
        "N tDCS",
        "N relationship action-sentences",
        "N superior temporal sulcus",
        "N reading",
        "#text"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 3.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2076-3425",
        "publisher": "Multidisciplinary Digital Publishing Institute (MDPI)",
        "sjr": 0.752,
        "snip": 0.938,
        "subject_areas": [
          "Neuroscience (all)"
        ],
        "title": "Brain sciences"
      },
      "publication_date": "2021-11-05",
      "selected": false,
      "title": "Personality Traits Modulate the Effect of tDCS on Reading Speed of Social Sentences.",
      "urls": []
    },
    {
      "abstract": "Conventional transcranial direct current stimulation (tDCS) protocols typically deliver 2 mA for 20-30 minutes. The most common administration uses a wet electrode approach which dries out in ~60 minutes at room temperature. This restricts its application to limited duration electrode-scalp contact use cases unless additional conductive media (saline, gel, or paste) is re-applied. This problem is further compounded by the subject's hair which not only presents administration challenges (interferes with electrode attachment and adhesion) but also acts as a conduit of current flow into the scalp resulting in current hotspots. This non-uniform current injection results in increased skin sensation. The aim of this study was to determine suitability of a commercially available hydrogel for DC delivery through hair. Experiments involved both non-clinical testing on an agar block and clinical testing on subjects' forearms. Electrodes were positioned on the posterior side of the forearm that has hair for the clinical testing. Typical dose as used in tDCS was delivered and pain scores were collected. Results indicate suitable current delivery performance and all subjects tolerated delivery with pain scores ranging between 0-6. Our study paves the way for future testing on the scalp for tDCS application.Clinical Relevance - This study demonstrates the possibility of delivering tDCS through hair via dry electrodes. Specific use cases that cannot use a traditional wet electrode approach stand to benefit from the results of our work. \u00c2\u00a9 2021 IEEE.",
      "authors": [
        "Valter, Yishai",
        "Shahabuddin, Syed",
        "McDonald, Neil",
        "Roberts, Brooke",
        "Soussou, Walid",
        "Thomas, Chris",
        "Datta, Abhishek"
      ],
      "categories": null,
      "citations": 1,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1109/EMBC46164.2021.9630579",
      "keywords": [],
      "number_of_pages": 4,
      "pages": "1584-1587",
      "publication": {
        "category": "Journal",
        "cite_score": 2.4,
        "is_potentially_predatory": false,
        "isbn": "9781728111797",
        "issn": "2694-0604",
        "publisher": "Institute of Electrical and Electronics Engineers Inc.",
        "sjr": 0.188,
        "snip": 0.938,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference"
      },
      "publication_date": "2021-11-01",
      "selected": false,
      "title": " Feasibility of Direct Current stimulation through hair using a dry electrode: potential for transcranial Direct Current Stimulation (tDCS) application.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85122549882&origin=inward"
      ]
    },
    {
      "abstract": "Background: Amygdala activity dysregulation plays a central role in post-traumatic stress disorder (PTSD). Hence learning to self-regulate one's amygdala activity may facilitate recovery. PTSD is further characterized by abnormal contextual processing related to the traumatic memory. Therefore, provoking the personal traumatic narrative while training amygdala down-regulation could enhance clinical efficacy. We report the results of a randomized controlled trial (NCT02544971) of a novel self-neuromodulation procedure (i.e. NeuroFeedback) for PTSD, aimed at down-regulating limbic activity while receiving feedback from an auditory script of a personal traumatic narrative. To scale-up applicability, neural activity was probed by an fMRI-informed EEG model of amygdala activity, termed Amygdala Electrical Finger-Print (AmygEFP). Methods: Fifty-nine adults meeting DSM-5 criteria for PTSD were randomized between three groups: Trauma-script feedback interface (Trauma-NF) or Neutral feedback interface (Neutral-NF), and a control group of No-NF (to control for spontaneous recovery). Before and immediately after 15 NF training sessions patients were blindly assessed for PTSD symptoms and underwent one session of amygdala fMRI-NF for transferability testing. Follow-up clinical assessment was performed at 3- and 6-months following NF treatment. Results: Patients in both NF groups learned to volitionally down-regulate AmygEFP signal and demonstrated a greater reduction in PTSD symptoms and improved down-regulation of the amygdala during fMRI-NF, compared to the No-NF group. The Trauma-NF group presented the largest immediate clinical improvement. Conclusions: This proof-of-concept study indicates the feasibility of the AmygEFP-NF process-driven as a scalable intervention for PTSD and illustrates its clinical potential. Further investigation is warranted to elucidate the contribution of AmygEFP-NF beyond exposure and placebo effects. \u00c2\u00a9 2021 The Authors",
      "authors": [
        "Fruchtman-Steinbok, Tom",
        "Keynan, Jackob N",
        "Cohen, Avihay",
        "Jaljuli, Iman",
        "Mermelstein, Shiri",
        "Drori, Gadi",
        "Routledge, Efrat",
        "Krasnoshtein, Michael",
        "Playle, Rebecca",
        "Linden, David E J",
        "Hendler, Talma"
      ],
      "categories": null,
      "citations": 13,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1016/j.nicl.2021.102859",
      "keywords": [
        "N fMRI",
        "D016428 Journal Article",
        "N Limbic activity",
        "D013485 Research Support, Non-U.S. Gov't",
        "D016449 Randomized Controlled Trial",
        "N Neuromodulation",
        "N EEG",
        "N Self-regulation"
      ],
      "number_of_pages": null,
      "pages": "102859",
      "publication": {
        "category": "Journal",
        "cite_score": 8.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2213-1582",
        "publisher": "Elsevier BV",
        "sjr": 1.395,
        "snip": 1.324,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Neurology (clinical)",
          "Radiology, Nuclear Medicine and Imaging",
          "Neurology"
        ],
        "title": "NeuroImage. Clinical"
      },
      "publication_date": "2021-10-15",
      "selected": false,
      "title": "Amygdala electrical-finger-print (AmygEFP) NeuroFeedback guided by individually-tailored Trauma script for post-traumatic stress disorder: Proof-of-concept.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85117584827&origin=inward"
      ]
    },
    {
      "abstract": "Objective. Approach. Main results. Significance. Brain-computer interface (BCI) is a tool that can be used to train brain self-regulation and influence specific activity patterns, including functional connectivity, through neurofeedback. The functional connectivity of the primary motor area (M1) and cerebellum play a critical role in motor recovery after a brain injury, such as stroke. The objective of this study was to determine the feasibility of achieving control of the functional connectivity between M1 and the cerebellum in healthy subjects. Additionally, we aimed to compare the brain self-regulation of two different feedback modalities and their effects on motor performance.Nine subjects were trained with a real-time functional magnetic resonance imaging BCI system. Two groups were conformed: equal feedback group (EFG), which received neurofeedback that weighted the contribution of both regions of interest (ROIs) equally, and weighted feedback group (WFG) that weighted each ROI differentially (30% cerebellum; 70% M1). The magnitude of the brain activity induced by self-regulation was evaluated with the blood-oxygen-level-dependent (BOLD) percent change (BPC). Functional connectivity was assessed using temporal correlations between the BOLD signal of both ROIs. A finger-tapping task was included to evaluate the effect of brain self-regulation on motor performance.A comparison between the feedback modalities showed that WFG achieved significantly higher BPC in M1 than EFG. The functional connectivity between ROIs during up-regulation in WFG was significantly higher than EFG. In general, both groups showed better tapping speed in the third session compared to the first. For WFG, there were significant correlations between functional connectivity and tapping speed.The results show that it is possible to train healthy individuals to control M1-cerebellum functional connectivity with rtfMRI-BCI. Besides, it is also possible to use a weighted feedback approach to facilitate a higher activity of one region over another.",
      "authors": [
        "Vargas, Patricia",
        "Sitaram, Ranganatha",
        "Sep\u00falveda, Pradyumna",
        "Montalba, Cristian",
        "Rana, Mohit",
        "Torres, Rafael",
        "Tejos, Cristi\u00e1n",
        "Ruiz, Sergio"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1088/1741-2552/ac2b7e",
      "keywords": [
        "N functional connectivity",
        "D016428 Journal Article",
        "N brain\u2013computer interfaces",
        "D013485 Research Support, Non-U.S. Gov't",
        "N neurofeedback",
        "N motor cortex",
        "N cerebellum"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1741-2552",
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Journal of neural engineering"
      },
      "publication_date": "2021-10-14",
      "selected": false,
      "title": "Weighted neurofeedback facilitates greater self-regulation of functional connectivity between the primary motor area and cerebellum.",
      "urls": []
    },
    {
      "abstract": "OBJECTIVES UNASSIGNED Individuals with subjective memory complaints and symptoms of depression and/or anxiety are at high risk for further cognitive decline, and possible progression to dementia. Low-burden interventions to help slow or prevent cognitive decline in this high-risk group are needed. The objective of this study is to assess the feasibility of combining Mindfulness-Based Stress Reduction (MBSR) with transcranial direct current stimulation (tDCS) to increase putative benefits of MBSR for cognitive function and everyday mindfulness in depressed or anxious older adults with subjective cognitive decline.\nMETHODS UNASSIGNED We conducted a two-site pilot double-blind randomized sham-controlled trial, combining active MBSR with either active or sham tDCS. The intervention included weekly in-class group sessions at the local university hospital and daily at-home practice. Anodal tDCS was applied for 30\u00a0min during MBSR meditative practice, both in-class and at-home.\nRESULTS UNASSIGNED n n d d F p F p (1,21) (1,21) Twenty-six individuals with subjective cognitive complaints and symptoms of depression and/or anxiety were randomized to active (\u2009=\u200912) or sham tDCS (\u2009=\u200914). The combination of MBSR and tDCS was safe and well tolerated, though at-home adherence and in-class attendance were variable. While they were not statistically significant, the largest effect sizes for active vs. sham tDCS were for everyday mindfulness (\u2009=\u20090.6) and social functioning (\u2009=\u20090.9) ( \u2009=\u20093.68, \u2009=\u20090.07 and  \u2009=\u20093.9, \u2009=\u20090.06, respectively).\nCONCLUSIONS UNASSIGNED Our findings suggest that it is feasible and safe to combine tDCS with MBSR in older depressed and anxious adults, including during remote, at-home use. Furthermore, tDCS may enhance MBSR via transferring its meditative learning and practice into increases in everyday mindfulness. Future studies need to improve adherence to MBSR with tDCS.\nTRIAL REGISTRATION UNASSIGNED ClinicalTrials.gov (NCT03653351 and NCT03680664).\nSUPPLEMENTARY INFORMATION UNASSIGNED The online version contains supplementary material available at 10.1007/s12671-021-01764-9.",
      "authors": [
        "Brooks, Heather",
        "Oughli, Hanadi Ajam",
        "Kamel, Lojine",
        "Subramanian, Subha",
        "Morgan, Gwen",
        "Blumberger, Daniel M",
        "Kloeckner, Jeanne",
        "Kumar, Sanjeev",
        "Mulsant, Benoit H",
        "Lenze, Eric J",
        "Rajji, Tarek K"
      ],
      "categories": null,
      "citations": 10,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1007/s12671-021-01764-9",
      "keywords": [
        "@UI",
        "N Subjective cognitive complaints",
        "N MBSR",
        "N tDCS",
        "N Mindfulness",
        "N Cognitive function",
        "N Late-life anxiety",
        "#text",
        "N Late-life depression"
      ],
      "number_of_pages": 13,
      "pages": "3047-3059",
      "publication": {
        "category": "Journal",
        "cite_score": 6.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1868-8527",
        "publisher": "Springer Verlag",
        "sjr": 1.259,
        "snip": 1.605,
        "subject_areas": [
          "Developmental and Educational Psychology",
          "Applied Psychology",
          "Health (social science)",
          "Experimental and Cognitive Psychology",
          "Social Psychology"
        ],
        "title": "Mindfulness"
      },
      "publication_date": "2021-10-05",
      "selected": false,
      "title": "Enhancing Cognition in Older Persons with Depression or Anxiety with a Combination of Mindfulness-Based Stress Reduction (MBSR) and Transcranial Direct Current Stimulation (tDCS): Results of a Pilot Randomized Clinical Trial.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85116459282&origin=inward"
      ]
    },
    {
      "abstract": "People with schizophrenia spectrum disorders (SSDs) often experience persistent social cognitive impairments, associated with poor functional outcome. There are currently no approved treatment options for these debilitating symptoms, highlighting the need for novel therapeutic strategies. Work to date has elucidated differential social processes and underlying neural circuitry affected in SSDs, which may be amenable to modulation using neurostimulation. Further, advances in functional connectivity mapping and electric field modeling may be used to identify individualized treatment targets to maximize the impact of brain stimulation on social cognitive networks. Here, we review literature supporting a roadmap for translating functional connectivity biomarker discovery to individualized treatment development for social cognitive impairments in SSDs. First, we outline the relevance of social cognitive impairments in SSDs. We review machine learning approaches for dimensional brain-behavior biomarker discovery, emphasizing the importance of individual differences. We synthesize research showing that brain stimulation techniques, such as repetitive transcranial magnetic stimulation, can be used to target relevant networks. Further, functional connectivity\u00e2\u0080\u0093based individualized targeting may enhance treatment response. We then outline recent approaches to account for neuroanatomical variability and optimize coil positioning to individually maximize target engagement. Overall, the synthesized literature provides support for the utility and feasibility of this translational approach to precision treatment. The proposed roadmap to translate biomarkers of social cognitive impairments to individualized treatment is currently under evaluation in precision-guided trials. Such a translational approach may also be applicable across conditions and generalizable for the development of individualized neurostimulation targeting other behavioral deficits. \u00c2\u00a9 2021 Society of Biological Psychiatry",
      "authors": [
        "Oliver, Lindsay D",
        "Hawco, Colin",
        "Viviano, Joseph D",
        "Voineskos, Aristotle N"
      ],
      "categories": null,
      "citations": 6,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1016/j.biopsych.2021.09.007",
      "keywords": [
        "N Transcranial magnetic stimulation",
        "N Machine learning",
        "D016428 Journal Article",
        "D052061 Research Support, N.I.H., Extramural",
        "N Biomarkers",
        "D016454 Review",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Functional connectivity",
        "N Schizophrenia spectrum disorders",
        "N Social cognition"
      ],
      "number_of_pages": 10,
      "pages": "699-708",
      "publication": {
        "category": "Journal",
        "cite_score": 19.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1873-2402",
        "publisher": "Elsevier USA",
        "sjr": 3.768,
        "snip": 2.412,
        "subject_areas": [
          "Biological Psychiatry"
        ],
        "title": "Biological psychiatry"
      },
      "publication_date": "2021-09-20",
      "selected": false,
      "title": "From the Group to the Individual in Schizophrenia Spectrum Disorders: Biomarkers of Social Cognitive Impairments and Therapeutic Translation.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85119188508&origin=inward"
      ]
    },
    {
      "abstract": "Perinatal mental illness refers to the most frequent mental health disorders that emerge during pregnancy and up to 12 months postpartum. When untreated, perinatal mental illness leads to devastating adverse impact that can affect not only newborn neurodevelopment but also the mother and family functioning, ultimately leading to negative social and economic impact to societies. The understanding of the most frequente perinatal mental health disorders (namely mood and anxiety disorders - PNMAD), the currently available treatments and the potential of transcranial direct current stimulation (tDCS) within the clinical algorithm will contribute to broaden the field and discuss alternatives that address women and healthcare professionals needs and values, consequently increasing adherence to treatment. In this chapter we aim to provide an overview of the most common PNMAD, discuss the transdiagnostic mechanisms and the neural underpinnings across PNMAD phenotypes, and review the state of the art regarding the use of tDCS as an alternative treatment. Finally, we discuss future avenues for research in tDCS treatments and precision interventions in PNMAD. Given the broad scope of the topics under discussion, where appropriate we refer to reviews that extensively discuss each one in depth. \u00c2\u00a9 Springer Nature Switzerland AG 2021. All rights reseverd.",
      "authors": [
        "Ganho-\u00c3\u0081vila, A.",
        "Guiomar, R.",
        "Pacheco, F."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1007/978-3-030-76136-3_16",
      "keywords": [
        "Postpartum psychosis",
        "PNMAD",
        "Anxiety",
        "Postpartum",
        "TDCS",
        "Depression",
        "Perinatal mood and anxiety disorders",
        "Pregnancy"
      ],
      "number_of_pages": 16,
      "pages": "313-328",
      "publication": {
        "category": "Book",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": "9783030761363",
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Transcranial Direct Current Stimulation in Neuropsychiatric Disorders: Clinical Principles and Management: Second Edition"
      },
      "publication_date": "2021-09-20",
      "selected": false,
      "title": "Transcranial direct current stimulation in the perinatal period",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85160461872&origin=inward"
      ]
    },
    {
      "abstract": "This chapter provides an overview of tDCS as a treatment for negative symptoms in schizophrenia. Negative symptoms are frequent during schizophrenia and have a debilitating impact on global functioning. They consist in lack of impetus and volition, impaired cognition, and social decline. Although positive symptoms of schizophrenia respond to antipsychotic pharmacotherapy, negative symptoms are usually refractory to pharmacotherapy. In this context, tDCS could help to improve such symptoms by restoring disturbed neural network connectivity in frontal hub regions. To date, there are several studies suggesting an improvement of negative symptoms by left-anodal and right-cathodal tDCS of the dorsolateral prefrontal cortex. Domiciliary use of tDCS could help to overcome difficulties in adherence in this severely ill population. \u00c2\u00a9 Springer Nature Switzerland AG 2021. All rights reseverd.",
      "authors": [
        "da Costa Lane Valiengo, L.",
        "Palm, U."
      ],
      "categories": null,
      "citations": 2,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1007/978-3-030-76136-3_24",
      "keywords": [
        "Negative symptoms",
        "Avolition",
        "Cognition",
        "Home use",
        "Transcranial direct current stimulation",
        "Schizophrenia",
        "Randomized clinical trials"
      ],
      "number_of_pages": 10,
      "pages": "501-510",
      "publication": {
        "category": "Book",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": "9783030761363",
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Transcranial Direct Current Stimulation in Neuropsychiatric Disorders: Clinical Principles and Management: Second Edition"
      },
      "publication_date": "2021-09-20",
      "selected": false,
      "title": "Schizophrenia: Negative symptoms",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85160460682&origin=inward"
      ]
    },
    {
      "abstract": "n n p p Clinical Trial Registration: About 30-45% of cerebral palsy (CP) patients have cognitive impairment. Previous studies showed the evidence that transcranial direct current stimulation (tDCS) may have some benefits in attention-deficit/hyperactivity disorder, autism spectrum disorder, and motor development in CP. The aim of this study is to evaluate the effect of tDCS on cognition, language, and activities of daily living (ADL) among children with CP with cognitive impairment. It was a pilot, randomized, controlled, double-blind, clinical trial in a tertiary pediatric hospital, and 13 children with CP and a cognitive age under 42 months were enrolled. tDCS group ( = 8) had active tDCS and cognitive training (20 min/session, total 20 sessions, for 12 weeks) and sham group ( = 5) had sham tDCS and cognitive training. Primary outcome was the Bayley Scales of Infant Development II (BSID II). Secondary outcomes were the Pediatric Evaluation of Disability Inventory (PEDI), the Laboratory Temperament Assessment Battery (Lab-TAB), the Early Childhood Behavior Questionnaire (ECBQ), the Korean version of MacArthur-Bates Communicative Development Inventories (M-B CDI-K), the Sequenced Language Scale for Infants (SELSI) and the Preschool Receptive-Expressive Language Scale (PRES). After intervention, the tDCS group showed significant improvements in all measurements ( < 0.05) except the M-B CDI-K (grammar), whereas the sham group only showed significant improvements in the Lab-TAB (manipulation domain), the ECBQ (attentional shifting), and the M-B CDI-K (comprehension). The between-group differences in the degree of post-intervention improvement were not statistically significant. The degree of improvement was associated with better baseline cognitive function and younger age ( < 0.05). There were no major adverse events after tDCS. The combined application of tDCS and cognitive training was feasible and associated with improvements in cognitive function, ADL, and language among children with CP with cognitive impairment. However, considering that it is a pilot study, further larger-scale systematic investigation is needed.  The trial was registered in the Clinical Research Information Service database, identifier: KCT0003023.",
      "authors": [
        "Ko, Eun Jae",
        "Hong, Mi Jin",
        "Choi, Eun Jung",
        "Yuk, Jin Sook",
        "Yum, Mi Sun",
        "Sung, In Young"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3389/fped.2021.713792",
      "keywords": [
        "N cognitive dysfunction",
        "N language",
        "@UI",
        "N cerebral palsy",
        "N transcranial direct current stimulation",
        "N child",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "713792",
      "publication": {
        "category": "Journal",
        "cite_score": 3.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2296-2360",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.798,
        "snip": 1.087,
        "subject_areas": [
          "Pediatrics, Perinatology and Child Health"
        ],
        "title": "Frontiers in pediatrics"
      },
      "publication_date": "2021-08-25",
      "selected": false,
      "title": "Effect of Anodal Transcranial Direct Current Stimulation Combined With Cognitive Training for Improving Cognition and Language Among Children With Cerebral Palsy With Cognitive Impairment: A Pilot, Randomized, Controlled, Double-Blind, and Clinical Trial.",
      "urls": []
    },
    {
      "abstract": "Objectives. The aim of this study was to use neurofeedback (NF) training as the add-on therapy in patients with schizophrenia to improve their clinical, cognitive, and psychosocial condition. The study, thanks to the monitoring of various conditions, quantitative electroencephalogram (QEEG) and brain-derived neurotrophic factor (BDNF), was supposed to give an insight into mechanisms underlying NF training results. Methods. Forty-four male patients with schizophrenia, currently in a stable, incomplete remission, were recruited into two, 3-month rehabilitation programs, with standard rehabilitation as a control group (R) or with add-on NF training (NF). Pre- and posttherapy primary outcomes were compared: clinical (Positive and Negative Syndrome Scale (PANSS)), cognitive (Color Trails Test (CTT), d2 test), psychosocial functioning (General Self-Efficacy Scale (GSES), Beck Cognitive Insight Scale (BCIS), and Acceptance of Illness Scale (AIS)), quantitative electroencephalogram (QEEG), auditory event-related potentials (ERPs), and serum level of BDNF. Results. Both groups R and NF improved significantly in clinical ratings (Positive and Negative Syndrome Scale (PANSS)). In-between analyses unveiled some advantages of add-on NF therapy over standard rehabilitation. GSES scores improved significantly, giving the NF group of patients greater ability to cope with stressful or difficult social demands. Also, the serum-level BDNF increased significantly more in the NF group. Post hoc analyses indicated the possibility of creating a separate PANSS subsyndrome, specifically related to cognitive, psychosocial, and BDNF effects of NF therapy. Conclusions. Neurofeedback can be effectively used as the add-on therapy in schizophrenia rehabilitation programs. The method requires further research regarding its clinical specificity and understanding mechanisms of action. \u00c2\u00a9 2021 Renata Markiewicz et al.",
      "authors": [
        "Markiewicz, Renata",
        "Markiewicz-Gospodarek, Agnieszka",
        "Dobrowolska, Beata",
        "\u0141oza, Bartosz"
      ],
      "categories": null,
      "citations": 7,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1155/2021/4488664",
      "keywords": [],
      "number_of_pages": null,
      "pages": "4488664",
      "publication": {
        "category": "Journal",
        "cite_score": 5.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1687-5443",
        "publisher": "Hindawi Publishing Corporation",
        "sjr": 0.766,
        "snip": 0.836,
        "subject_areas": [
          "Neurology (clinical)",
          "Neurology"
        ],
        "title": "Neural plasticity"
      },
      "publication_date": "2021-08-12",
      "selected": false,
      "title": "Improving Clinical, Cognitive, and Psychosocial Dysfunctions in Patients with Schizophrenia: A Neurofeedback Randomized Control Trial.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85113434028&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND AND AIMS Nicotine is a highly addictive substance in tobacco products that dysregulates several neurotransmitters in the brain and impairs executive function. Non-invasive brain stimulation (NIBS) methods such as repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) are promising treatments for nicotine dependence. We investigated the efficacy and acceptability of NIBS in managing smoking cessation through a systematic review and network meta-analysis (NMA).\nMETHODS We conducted a systematic review to identify randomized controlled trials (RCTs) that investigated the efficacy of NIBS for smoking cessation. All pairwise meta-analyses and NMA procedures were conducted using random-effects and frequentist models. The co-primary outcomes were (1) the change in number of cigarettes smoked per day (change in frequency of smoking) in patients with nicotine dependence after NIBS and (2) acceptability (the dropout rate). The effect sizes for co-primary outcomes of change in frequency of smoking and acceptability were assessed according to standardized mean difference (SMD) and odds ratio, respectively.\nRESULTS Twelve RCTs with 710 participants (mean age: 44.2\u00a0years, 31.2% female) were included. Compared with the sham control, 10-Hz rTMS over the left dorsolateral prefrontal cortex (DLPFC) was associated with the largest changes in smoking frequency [SMD\u00a0=\u00a0-1.22, 95% confidence interval (95% CI)\u00a0=\u00a0-1.77 to -0.66]. The 2-mA bifrontal tDCS (SMD\u00a0=\u00a0-0.97, 95% CI\u00a0=\u00a0-1.32 to -0.62) and 10-Hz deep rTMS over the bilateral DLPFC with cue provocation (SMD\u00a0=\u00a0-0.77, 95% CI\u00a0=\u00a0-1.20 to -0.34) were associated with a significantly larger decrease in smoking frequency versus the sham. None of the investigated NIBSs was associated with dropout rates significantly different from those of the sham control groups.\nCONCLUSION Prefrontal non-invasive brain stimulation interventions appear to reduce the number of cigarettes smoked with good acceptability.",
      "authors": [
        "Tseng, Ping-Tao",
        "Jeng, Jia-Shyun",
        "Zeng, Bing-Syuan",
        "Stubbs, Brendon",
        "Carvalho, Andre F",
        "Brunoni, Andre R",
        "Su, Kuan-Pin",
        "Tu, Yu-Kang",
        "Wu, Yi-Cheng",
        "Chen, Tien-Yu",
        "Lin, Pao-Yen",
        "Liang, Chih-Sung",
        "Hsu, Chih-Wei",
        "Chen, Yen-Wen",
        "Li, Cheng-Ta"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1111/add.15624",
      "keywords": [
        "N non-invasive brain stimulation",
        "N nicotine dependence",
        "D016428 Journal Article",
        "N Benefit",
        "D016454 Review",
        "D013485 Research Support, Non-U.S. Gov't",
        "N smoke cessation",
        "N network meta-analysis",
        "D017418 Meta-Analysis",
        "N safety",
        "D000078182 Systematic Review"
      ],
      "number_of_pages": 13,
      "pages": "1830-1842",
      "publication": {
        "category": "Journal",
        "cite_score": 10.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1360-0443",
        "publisher": "Wiley-Blackwell Publishing Ltd",
        "sjr": 2.177,
        "snip": 2.021,
        "subject_areas": [
          "Medicine (miscellaneous)",
          "Psychiatry and Mental Health"
        ],
        "title": "Addiction (Abingdon, England)"
      },
      "publication_date": "2021-08-04",
      "selected": false,
      "title": "Efficacy of non-invasive brain stimulation interventions in reducing smoking frequency in patients with nicotine dependence: a systematic review and network meta-analysis of randomized controlled trials.",
      "urls": []
    },
    {
      "abstract": "Top-tier evidence on the safety/tolerability of 80 medications in children/adolescents with mental disorders has recently been reviewed in this\u00c2 jour\u00c2\u00adnal.\u00c2 To guide clinical practice, such data must be combined with evidence on efficacy and acceptability. Besides medications, psychosocial\u00c2 inter\u00c2\u00adventions and brain stimulation techniques are treatment options for children/adolescents with mental disorders. For this umbrella review, we\u00c2 systematically searched network meta-analyses (NMAs) and meta-analyses (MAs) of randomized controlled trials (RCTs) evaluating 48 medications, 20 psychosocial interventions, and four brain stimulation techniques in children/adolescents with 52 different mental disorders or groups of mental disorders, reporting on 20 different efficacy/acceptability outcomes. Co-primary outcomes were disease-specific symptom reduction and all-cause discontinuation (\u00e2\u0080\u009cacceptability\u00e2\u0080\u009d). We included 14 NMAs and 90 MAs, reporting on 15 mental disorders or groups of mental disorders. Overall, 21 medications outperformed placebo regarding the co-primary outcomes, and three psychosocial interventions did so (while seven outperformed waiting list/no treatment). Based on the meta-analytic evidence, the most convincing efficacy profile emerged for amphetamines, methylphenidate and, to a smaller extent, behavioral therapy in attention-deficit/hyperactivity disorder; aripiprazole, risperidone and several psychosocial interventions in autism; risperidone and behavioral interventions in disruptive behavior disorders; several antipsychotics in schizophrenia spectrum disorders; fluoxetine, the combination of fluoxetine and cognitive behavioral therapy (CBT), and interpersonal therapy in depression; aripiprazole in mania; fluoxetine and group CBT in anxiety disorders; fluoxetine/selective serotonin reuptake inhibitors, CBT, and behavioral therapy with exposure and response prevention in obsessive-compulsive disorder; CBT in post-traumatic stress disorder; imipramine and alarm behavioral intervention in enuresis; behavioral therapy in encopresis; and family therapy in anorexia nervosa. Results from this umbrella review of interventions for mental disorders in children/adolescents provide evidence-based information for clinical decision making. \u00c2\u00a9 2021 World Psychiatric Association",
      "authors": [
        "Correll, C.U.",
        "Cortese, S.",
        "Croatto, G.",
        "Monaco, F.",
        "Krinitski, D.",
        "Arrondo, G.",
        "Ostinelli, E.",
        "Zangani, C.",
        "Fornaro, M.",
        "Estrad\u00c3\u00a9, A.",
        "Fusar-Poli, P.",
        "Carvalho, A.F.",
        "Solmi, M."
      ],
      "categories": null,
      "citations": 63,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1002/wps.20881",
      "keywords": [
        "adolescents",
        "psychotherapies",
        "ADHD",
        "acceptability",
        "psychosocial interventions",
        "autism",
        "efficacy",
        "brain stimulation",
        "dis\u00c2\u00adruptive behavior disorders",
        "pharmacotherapy",
        "Children"
      ],
      "number_of_pages": 32,
      "pages": "244-275",
      "publication": {
        "category": "Journal",
        "cite_score": 63.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "17238617",
        "publisher": "Wiley-Blackwell",
        "sjr": 14.306,
        "snip": 11.452,
        "subject_areas": [
          "Psychiatric Mental Health",
          "Psychiatry and Mental Health"
        ],
        "title": "World Psychiatry"
      },
      "publication_date": "2021-06-01",
      "selected": false,
      "title": "Efficacy and acceptability of pharmacological, psychosocial, and brain stimulation interventions in children and adolescents with mental disorders: an umbrella review",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85105929584&origin=inward"
      ]
    },
    {
      "abstract": "Aphasia, impairment of language after stroke or other neurological insult, is a common and often devastating condition that affects nearly every social activity and interaction. Behavioral speech and language therapy is the mainstay of treatment, although other interventions have been introduced to augment the effects of the behavioral therapy. In this narrative review, we discuss advances in aphasia therapy in the last 5 years and focus primarily on properly powered, randomized, controlled trials of both behavioral therapies and interventions to augment therapy for post-stroke aphasia. These trials include evaluation of behavioral therapies and computer-delivered language therapies. We also discuss outcome prediction trials as well as interventional trials that have employed noninvasive brain stimulation, or medications to augment language therapy. Supported by evidence from Phase III trials and large meta-analyses, it is now generally accepted that aphasia therapy can improve language processing for many patients. Not all patients respond similarly to aphasia therapy with the most severe patients being the least likely responders. Nevertheless, it is imperative that all patients, regardless of severity, receive aphasia management focused on direct therapy of language deficits, counseling, or both. Emerging evidence from Phase II trials suggests transcranial brain stimulation is a promising method to boost aphasia therapy outcomes.",
      "authors": [
        "Fridriksson, Julius",
        "Hillis, Argye Elizabeth"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.5853/jos.2020.05015",
      "keywords": [
        "N Speech therapy",
        "N Language therapy",
        "D016428 Journal Article",
        "D016454 Review",
        "N Brain",
        "N Aphasia",
        "N Stroke"
      ],
      "number_of_pages": 19,
      "pages": "183-201",
      "publication": {
        "category": "Journal",
        "cite_score": 10.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2287-6391",
        "publisher": "Korean Stroke Society",
        "sjr": 2.079,
        "snip": 2.175,
        "subject_areas": [
          "Neurology (clinical)",
          "Cardiology and Cardiovascular Medicine"
        ],
        "title": "Journal of stroke"
      },
      "publication_date": "2021-05-31",
      "selected": false,
      "title": "Current Approaches to the Treatment of Post-Stroke Aphasia.",
      "urls": []
    },
    {
      "abstract": "PURPOSE The aim was to compare the outcomes of upper airway stimulation (Stim) and other upper airway surgical procedures (Surg) in the treatment of obstructive sleep apnea (OSA).\nMETHODS Data sources included PubMed, Ovid MEDLINE, Cochrane Library, Web of Science, Scopus, and reference lists. Relevant articles were identified from various databases according to the PRISMA guidelines.\nRESULTS Five articles with a total of 990 patients were included. The mean cure rates in the Stim group and the Surg group was 63% and 22%, and the mean success rates was 86% and 51% which were higher in the Stim group (p\u2009<\u20090.001). The apnea-hypopnea index reduction was -23.9 events/ hour (MD, 95% CI -25.53, -22.29) in the Stim group and -15.5 events/hour (MD, 95% CI -17.50, -13.45) in the Surg group which was greater in the Stim group (P\u2009<\u20090.001). Epworth Sleepiness Scale decreased -4.9 (MD, 95% CI -5.45, -4.32) in the Stim group and -5.1 (MD 95% CI -5.88, -4.37) in the Surg group without significant difference between the groups (P\u2009=\u20090.62). Oxygen saturation nadir improvement was 8.5% (MD 95% CI 7.05%, 9.92%) in the Stim group and 2.2% (MD 95% CI-0.22%, 4.58%) in the Surg group which was higher in the Stim group (P\u2009<\u20090.001). Hospital stay and readmission rate were lower in the Stim group. The timing of follow-up ranged from 2 to 13\u00a0months.\nCONCLUSION Upper airway stimulation provides improved objective and similar subjective outcomes compared to other upper airway surgical procedures for selected patients with\u00a0moderate to severe OSA with difficulty adhering to CPAP treatment. However, further studies are essential to confirm outcomes in the long term.",
      "authors": [
        "Neruntarat, Chairat",
        "Wanichakorntrakul, Pisit",
        "Khuancharee, Kitsarawut",
        "Saengthong, Petcharat",
        "Tangngekkee, Mongkol"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1007/s11325-021-02402-3",
      "keywords": [
        "D016428 Journal Article",
        "N Upper airway stimulation",
        "D003160 Comparative Study",
        "N Systematic review",
        "N Meta-analysis",
        "D017418 Meta-Analysis",
        "N Obstructive sleep apnea",
        "N Upper airway surgery"
      ],
      "number_of_pages": 12,
      "pages": "407-418",
      "publication": {
        "category": "Journal",
        "cite_score": 4.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1522-1709",
        "publisher": "Springer Verlag",
        "sjr": 0.685,
        "snip": 1.096,
        "subject_areas": [
          "Neurology (clinical)",
          "Otorhinolaryngology"
        ],
        "title": "Sleep & breathing = Schlaf & Atmung"
      },
      "publication_date": "2021-05-17",
      "selected": false,
      "title": "Upper airway stimulation vs other upper airway surgical procedures for OSA: a meta-analysis.",
      "urls": []
    },
    {
      "abstract": "BACKGROUND/OBJECTIVES Obesity has recently been recognized as a neurocognitive disorder involving circuits associated with the reward system and the dorsolateral prefrontal cortex (DLPFC). Noninvasive brain stimulation (NIBS) has been proposed as a strategy for the management of obesity. However, the results have been inconclusive. The aim of the current network meta-analysis (NMA) was to evaluate the efficacy and acceptability of different NIBS modalities for weight reduction in participants with obesity.\nMETHODS Randomized controlled trials (RCTs) examining NIBS interventions in patients with obesity were analyzed using the frequentist model of NMA. The coprimary outcome was change in body mass index (BMI) and acceptability, which was calculated using the dropout rate.\nRESULTS Overall, the current NMA, consisting of eight RCTs, revealed that the high-frequency repetitive transcranial magnetic stimulation (TMS) over the left DLPFC was ranked to be associated with the second-largest decrease in BMI and the largest decrease in total energy intake and craving severity, whereas the high-frequency deep TMS over bilateral DLPFC and the insula was ranked to be associated with the largest decrease in BMI.\nCONCLUSION This pilot study provided a \"signal\" for the design of more methodologically robust and larger RCTs based on the findings of the potentially beneficial effect on weight reduction in participants with obesity by different NIBS interventions.",
      "authors": [
        "Zeng, Bing-Yan",
        "Zeng, Bing-Syuan",
        "Chen, Yen-Wen",
        "Hung, Chao-Ming",
        "Sun, Cheuk-Kwan",
        "Cheng, Yu-Shian",
        "Stubbs, Brendon",
        "Carvalho, Andre F",
        "Brunoni, Andre R",
        "Su, Kuan-Pin",
        "Tu, Yu-Kang",
        "Wu, Yi-Cheng",
        "Chen, Tien-Yu",
        "Lin, Pao-Yen",
        "Liang, Chih-Sung",
        "Hsu, Chih-Wei",
        "Tseng, Ping-Tao",
        "Li, Cheng-Ta"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1038/s41366-021-00833-2",
      "keywords": [],
      "number_of_pages": 12,
      "pages": "1705-1716",
      "publication": {
        "category": "Journal",
        "cite_score": 9.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1476-5497",
        "publisher": "Nature Publishing Group",
        "sjr": 1.438,
        "snip": 1.398,
        "subject_areas": [
          "Medicine (miscellaneous)",
          "Nutrition and Dietetics",
          "Endocrinology, Diabetes and Metabolism"
        ],
        "title": "International journal of obesity (2005)"
      },
      "publication_date": "2021-05-10",
      "selected": false,
      "title": "Efficacy and acceptability of noninvasive brain stimulation interventions for weight reduction in obesity: a pilot network meta-analysis.",
      "urls": []
    },
    {
      "abstract": "Attention deficit hyperactivity disorder (ADHD) is a pervasive condition affecting persons across all age groups, although it is primarily diagnosed in children. This neurological condition affects behavior, learning, and social adjustment and requires specific symptomatic criteria to be fulfilled for diagnosis. ADHD may be treated with a combination of psychological or psychiatric therapeutic interventions, but it often goes unattended. People with ADHD face societal bias challenges that impact how they manage the disorder and how they view themselves. This paper summarizes the present state of understanding of this disorder, with particular attention to early diagnosis and innovative therapeutic intervention. Contemporary understanding of the mind\u00e2\u0080\u0093brain duality allows for innovative therapeutic interventions based on neurological stimulation. This paper introduces the concept of neurostimulation as a therapeutic intervention for ADHD and poses the question of the relationship between patient adherence to self-administered therapy and the aesthetic design features of the neurostimulation device. By fabricating devices that go beyond safety and efficacy to embrace the aesthetic preferences of the patient, it is proposed that there will be improvements in patient adherence to a device intended to address ADHD. \u00c2\u00a9 2021 by the authors. Licensee MDPI, Basel, Switzerland.",
      "authors": [
        "Camp, Allyson",
        "Pastrano, Amanda",
        "Gomez, Valeria",
        "Stephenson, Kathleen",
        "Delatte, William",
        "Perez, Brianna",
        "Syas, Hunter",
        "Guiseppi-Elie, Anthony"
      ],
      "categories": null,
      "citations": 3,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.3390/bioengineering8050056",
      "keywords": [
        "N design",
        "N neurostimulation",
        "#text",
        "N ADHD",
        "N adherence",
        "N therapy",
        "@UI"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 4.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2306-5354",
        "publisher": "MDPI AG",
        "sjr": 0.663,
        "snip": 1.004,
        "subject_areas": [
          "Bioengineering"
        ],
        "title": "Bioengineering (Basel, Switzerland)"
      },
      "publication_date": "2021-05-01",
      "selected": false,
      "title": "Understanding ADHD: Toward an Innovative Therapeutic Intervention.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85106563518&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND BACKGROUND A fundamental challenge for many people with severe mental illness (SMI) is how to deal with cognitive impairments. Cognitive impairments are common in this population and limit daily functioning. Moreover, neural plasticity in people with SMI appears to be reduced, a factor that might hinder newly learned cognitive skills to sustain. The objective of this pilot trial is to investigate the effects of cognitive remediation (CR) on cognitive and daily functioning in people dependent on residential settings. In addition, transcranial direct current stimulation (tDCS) is used to promote neural plasticity. It is expected that the addition of tDCS can enhance learning and will result in longer-lasting improvements in cognitive and daily functioning.\nMETHODS METHODS This is a pragmatic, triple-blinded, randomized, sham-controlled, pilot trial following a non-concurrent multiple baseline design with the participants serving as their own control. We will compare (1) CR to treatment as usual, (2) active/sham tDCS+CR to treatment as usual, and (3) active tDCS+CR to sham tDCS+CR. Clinical relevance, feasibility, and acceptability of the use of CR and tDCS will be evaluated. We will recruit 26 service users aged 18\u2009years or older, with a SMI and dependent on residential facilities. After a 16-week waiting period (treatment as usual), which will serve as a within-subject control condition, participants will be randomized to 16 weeks of twice weekly\u00a0CR combined with active (N\u2009=\u200913) or sham tDCS (N\u2009=\u200913). Cognitive, functional, and clinical outcome assessments will be performed at baseline, after the control (waiting) period, directly after treatment, and 6-months post-treatment.\nDISCUSSION CONCLUSIONS The addition of cognitive interventions to treatment as usual may lead to long-lasting improvements in\u00a0the cognitive and daily functioning of service users dependent on residential facilities. This pilot trial will evaluate whether CR on its own or in combination with tDCS can be a clinically relevant addition to further enhance recovery. In case the results indicate that cognitive performance can be improved with CR,\u00a0and whether or not tDCS will lead to additional improvement, this pilot trial will be extended to a large randomized multicenter study.\nTRIAL REGISTRATION BACKGROUND Dutch Trial Registry NL7954 . Prospectively registered on August 12, 2019.",
      "authors": [
        "Poppe, Anika",
        "Bais, Leonie",
        "van Duin, Dani\u00eblle",
        "\u0106ur\u010di\u0107-Blake, Branislava",
        "Pijnenborg, Gerdina Hendrika Maria",
        "van der Meer, Lisette"
      ],
      "categories": null,
      "citations": 2,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1186/s13063-021-05230-8",
      "keywords": [
        "N Deinstitutionalization",
        "N Randomized controlled trial",
        "N Cognitive remediation training",
        "D016428 Journal Article",
        "N Transcranial direct current stimulation",
        "N Social and functional recovery",
        "D000078325 Clinical Trial Protocol",
        "N Severe mental illness"
      ],
      "number_of_pages": null,
      "pages": "275",
      "publication": {
        "category": "Journal",
        "cite_score": 3.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1745-6215",
        "publisher": "BioMed Central Ltd.",
        "sjr": 0.814,
        "snip": 0.827,
        "subject_areas": [
          "Medicine (miscellaneous)",
          "Pharmacology (medical)"
        ],
        "title": "Trials"
      },
      "publication_date": "2021-04-13",
      "selected": false,
      "title": "Improving cognition in severe mental illness by combining cognitive remediation and transcranial direct current stimulation: study protocol for a pragmatic randomized controlled pilot trial (HEADDSET).",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85104234230&origin=inward"
      ]
    },
    {
      "abstract": "PURPOSE OBJECTIVE \u00ae To find a reliable method to determine the wearing times of glasses in adults objectively on the basis of temperature measurements of the small-sized theramon thermosensor device (TM) from orthodontics. Furthermore, the reliability of the determined wearing times during well and poor position of spectacles was explored. To address the previously reported lack of accuracy during higher outside temperatures, this study was conducted in midsummer and autumn.\nPATIENTS AND METHODS METHODS Twenty adults wore their spectacles with three TMs attached to both inner sides and the right outer side in a period of three consecutive days. They were asked to report wearing and non-wearing times, indoor and outdoor activities and subjective perception of spectacle position as accurately as possible. To find the most reliable way to determine spectacle wearing times compared to protocolled wearing times, we applied and evaluated temperature categorizing methods and visual analysis of time logged temperatures. Percent error and percent accuracy of each method were calculated. The methods mentioned were applied and evaluated to determine poor spectacle position.\nRESULTS RESULTS Median percent errors of the most reliable determination methods were <10% with an accuracy between 90% and 96%. Comparing the most reliable methods, determinations on the basis of midsummer measurements (median percent error 0% to 2%, median percent accuracy 96%) were more accurate than on the basis of autumn measurements (median percent error -5% to -20%, median percent accuracy 90%). Poor spectacle position could be determined with a median percent error of 0% and a median percent accuracy of 100% by analysing the temperature measurements of TM's visually.\nCONCLUSION CONCLUSIONS A reliable and objective determination of spectacle wearing times is possible on the basis of TM temperature measurements in a standard clinical setting. Measurements of one inner TM seem to be sufficient to determine the wearing times and are more appealing. Poor spectacle position can be determined reliably by analysing visually the time logged temperatures. The findings of this study require further studies on larger groups of affected, amblyopic patients and children, to analyse the real impact of spectacle wearing times and poor spectacle position on visual development.",
      "authors": [
        "Abaza, Annegret",
        "Wahl, Gideon",
        "Kort\u00fcm, Constanze",
        "Januschowski, Kai",
        "Besch, Dorothea",
        "Schramm, Charlotte"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.2147/OPTH.S287508",
      "keywords": [
        "@UI",
        "N amblyopia",
        "N theramon\u00ae thermosensor",
        "N spectacle wearing times",
        "N objective monitoring",
        "N spectacle adherence",
        "#text"
      ],
      "number_of_pages": 15,
      "pages": "1375-1389",
      "publication": {
        "category": "Journal",
        "cite_score": 3.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1177-5467",
        "publisher": "Dove Medical Press Ltd.",
        "sjr": 0.76,
        "snip": 1.16,
        "subject_areas": [
          "Ophthalmology"
        ],
        "title": "Clinical ophthalmology (Auckland, N.Z.)"
      },
      "publication_date": "2021-03-31",
      "selected": false,
      "title": "\u00ae Objective Monitoring of Spectacle Wearing Times in Adult Subjects Using the Theramon Thermosensor.",
      "urls": []
    },
    {
      "abstract": "Autism spectrum disorder is characterized by abnormal function in core social brain regions. Here, we demonstrate the feasibility of real-time functional magnetic resonance imaging volitional neurofeedback. Following up the demonstration of neuromodulation in healthy participants, in this repeated-measure design clinical trial, 15 autism spectrum disorder patients were enrolled in a 5-session training program of real-time functional magnetic resonance imaging neurofeedback targeting facial emotion expressions processing, using the posterior superior temporal sulcus as region-of-interest. Participants were able to modulate brain activity in this region-of-interest, over multiple sessions. Moreover, we identified the relevant clinical and neural effects, as documented by whole-brain neuroimaging results and neuropsychological measures, including emotion recognition of fear, immediately after the intervention and persisting after 6 months. Neuromodulation profiles demonstrated subject-specificity for happy, sad, and neutral facial expressions, an unsurprising variable pattern in autism spectrum disorder. Modulation occurred in negative or positive directions, even for neutral faces, in line with their often-perceived ambiguity in autism spectrum disorder. Striatal regions (associated with success/failure of neuromodulation), saliency (insula/anterior cingulate cortex), and emotional control (medial prefrontal cortex) networks were recruited during neuromodulation. Recruitment of the operant learning network is consistent with participants\u00e2\u0080\u0099 engagement. Compliance, immediate intervention benefits, and their persistence after 6 months pave the way for a future Phase IIb/III, randomized controlled clinical trial, with a larger sample that will allow to conclude on clinical benefits from neurofeedback training in autism spectrum disorder (NCT02440451). Lay abstract: Neurofeedback is an emerging therapeutic approach in neuropsychiatric disorders. Its potential application in autism spectrum disorder remains to be tested. Here, we demonstrate the feasibility of real-time functional magnetic resonance imaging volitional neurofeedback in targeting social brain regions in autism spectrum disorder. In this clinical trial, autism spectrum disorder patients were enrolled in a program with five training sessions of neurofeedback. Participants were able to control their own brain activity in this social brain region, with positive clinical and neural effects. Larger, controlled, and blinded clinical studies will be required to confirm the benefits. \u00c2\u00a9 The Author(s) 2021.",
      "authors": [
        "Direito, Bruno",
        "Mouga, Susana",
        "Sayal, Alexandre",
        "Sim\u00f5es, Marco",
        "Quental, Hugo",
        "Bernardino, In\u00eas",
        "Playle, Rebecca",
        "McNamara, Rachel",
        "Linden, David Ej",
        "Oliveira, Guiomar",
        "Castelo Branco, Miguel"
      ],
      "categories": null,
      "citations": 7,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1177/13623613211002052",
      "keywords": [
        "N posterior superior temporal sulcus",
        "D016428 Journal Article",
        "N autism spectrum disorder",
        "N social cognition",
        "N real-time functional magnetic resonance imaging",
        "N neurofeedback",
        "D013485 Research Support, Non-U.S. Gov't",
        "N neurorehabilitation",
        "D017427 Clinical Trial, Phase II"
      ],
      "number_of_pages": 15,
      "pages": "1746-1760",
      "publication": {
        "category": "Journal",
        "cite_score": 9.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1461-7005",
        "publisher": "SAGE Publications Ltd",
        "sjr": 1.767,
        "snip": 2.238,
        "subject_areas": [
          "Developmental and Educational Psychology"
        ],
        "title": "Autism : the international journal of research and practice"
      },
      "publication_date": "2021-03-25",
      "selected": true,
      "title": "Training the social brain: Clinical and neural effects of an 8-week real-time functional magnetic resonance imaging neurofeedback Phase IIa Clinical Trial in Autism.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85103153933&origin=inward"
      ]
    },
    {
      "abstract": "Mental workload is a neuroergonomic human factor, which is widely used in planning a system's safety and areas like brain\u00e2\u0080\u0093machine interface (BMI), neurofeedback, and assistive technologies. Robotic prosthetics methodologies are employed for assisting hemiplegic patients in performing routine activities. Assistive technologies' design and operation are required to have an easy interface with the brain with fewer protocols, in an attempt to optimize mobility and autonomy. The possible answer to these design questions may lie in neuroergonomics coupled with BMI systems. In this study, two human factors are addressed: designing a lightweight wearable robotic exoskeleton hand that is used to assist the potential stroke patients with an integrated portable brain interface using mental workload (MWL) signals acquired with portable functional near-infrared spectroscopy (fNIRS) system. The system may generate command signals for operating a wearable robotic exoskeleton hand using two-state MWL signals. The fNIRS system is used to record optical signals in the form of change in concentration of oxy and deoxygenated hemoglobin (HbO and HbR) from the pre-frontal cortex (PFC) region of the brain. Fifteen participants participated in this study and were given hand-grasping tasks. Two-state MWL signals acquired from the PFC region of the participant's brain are segregated using machine learning classifier\u00e2\u0080\u0094support vector machines (SVM) to utilize in operating a robotic exoskeleton hand. The maximum classification accuracy is 91.31%, using a combination of mean-slope features with an average information transfer rate (ITR) of 1.43. These results show the feasibility of a two-state MWL (fNIRS-based) robotic exoskeleton hand (BMI system) for hemiplegic patients assisting in the physical grasping tasks. \u00c2\u00a9 Copyright \u00c2\u00a9 2021 Asgher, Khan, Asif Nizami, Khalil, Ahmad, Ayaz and Naseer.",
      "authors": [
        "Asgher, U.",
        "Khan, M.J.",
        "Asif Nizami, M.H.",
        "Khalil, K.",
        "Ahmad, R.",
        "Ayaz, Y.",
        "Naseer, N."
      ],
      "categories": null,
      "citations": 13,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3389/fnbot.2021.605751",
      "keywords": [
        "brain machine interface (BMI)",
        "machine learning (ML)",
        "brain computer interface (BCI)",
        "exoskeleton",
        "mental workload (MWL)",
        "neuroergonomics",
        "bionic actuating behavior",
        "functional near infrared spectroscopy (fNIRS)"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Frontiers in Neurorobotics"
      },
      "publication_date": "2021-03-18",
      "selected": false,
      "title": "Motor Training Using Mental Workload (MWL) With an Assistive Soft Exoskeleton System: A Functional Near-Infrared Spectroscopy (fNIRS) Study for Brain\u2013Machine Interface (BMI)",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85103519100&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND Randomized trials of complex interventions are increasingly including qualitative components to further understand factors that contribute to their success. In this paper, we explore the experiences of health care practitioners in a province wide smoking cessation program (the Smoking Treatment for Ontario Patients program) who participated in the COMBAT trial. This trial examined if the addition of an electronic prompt embedded in a Clinical Decision Support System (CDSS)-designed to prompt practitioners to Screen, provide a Brief intervention and Referral to Treatment (SBIRT) to patients who drank alcohol above the amounts recommended by the Canadian Cancer Society guidelines-influenced the proportion of practitioners delivering a brief intervention to their eligible patients. We wanted to understand the factors influencing implementation and acceptability of delivering a brief alcohol intervention for treatment-seeking smokers for health care providers who had access to the CDSS (intervention arm) and those who did not (control arm).\nMETHODS Twenty-three health care practitioners were selected for a qualitative interview using stratified purposeful sampling (12 from the control arm and 11 from the intervention arm). Interviews were 45 to 90\u00a0min in length and conducted by phone using an interview guide that was informed by the National Implementation Research Network's Hexagon tool. Interview recordings were transcribed and coded iteratively between three researchers to achieve consensus on emerging themes. The preliminary coding structure was developed using the National Implementation Research Network's Hexagon Tool framework and data was analyzed using the framework analysis approach.\nRESULTS Seventy eight percent (18/23) of the health care practitioners interviewed recognized the need to simultaneously address alcohol and tobacco use. Seventy four percent (17/23), were knowledgeable about the evidence of health risks associated with dual alcohol and tobacco use but 57% (13/23) expressed concerns with using the Canadian Cancer Society guidelines to screen for alcohol use. Practitioners acknowledged the value of adding a validated screening tool to the STOP program's baseline questionnaire (19/23); however, following through with a brief intervention and referral to treatment proved challenging due to lack of training, limited time, and fear of stigmatizing patients. Practitioners in the intervention arm (5/11; 45%) might not follow the recommendations from CDSS if these recommendations are not perceived as beneficial to the patients.\nCONCLUSIONS The results of the study show that practitioners' beliefs were reflective of the current social norms around alcohol use and this influenced their decision to offer a brief alcohol intervention. Future interventions need to emphasize both organizational and sociocultural factors as part of the design. The results of this study point to the need to change social norms regarding alcohol in order to effectively implement interventions that target both alcohol and tobacco use in primary care clinics. Trial registration ClinicalTrials.gov NCT03108144. Retrospectively registered 11 April 2017, https://www.clinicaltrials.gov/ct2/show/NCT03108144.",
      "authors": [
        "Minian, Nadia",
        "Noormohamed, Aliya",
        "Lingam, Mathangee",
        "Zawertailo, Laurie",
        "Le Foll, Bernard",
        "Rehm, J\u00fcrgen",
        "Giesbrecht, Norman",
        "Samokhvalov, Andriy V",
        "Baliunas, Dolly",
        "Selby, Peter"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1186/s13722-021-00225-x",
      "keywords": [
        "D016428 Journal Article",
        "N Clinical Decision Support System",
        "N Primary Health Care",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Tobacco",
        "N Hexagon Tool",
        "N Smoking cessation",
        "N Alcohol drinking",
        "N Qualitative Interviews"
      ],
      "number_of_pages": null,
      "pages": "17",
      "publication": {
        "category": "Journal",
        "cite_score": 4.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1940-0640",
        "publisher": "BioMed Central Ltd.",
        "sjr": 1.166,
        "snip": 0.956,
        "subject_areas": [
          "Psychiatry and Mental Health",
          "Clinical Psychology"
        ],
        "title": "Addiction science & clinical practice"
      },
      "publication_date": "2021-03-16",
      "selected": false,
      "title": "Integrating a brief alcohol intervention with tobacco addiction treatment in primary care: qualitative study of health care practitioner perceptions.",
      "urls": []
    },
    {
      "abstract": "Transcranial direct current stimulation (tDCS) is a novel treatment option for major depression which could be provided as a first-line treatment. tDCS is a non-invasive form of transcranial stimulation which changes cortical tissue excitability by applying a weak (0.5-2\u2009mA) direct current via scalp electrodes. Anodal and cathodal stimulation leads to depolarisation and hyperpolarisation, respectively, and cumulative effects are observed with repeated sessions. The montage in depression most often involves anodal stimulation to the left dorsolateral prefrontal cortex. Rates of clinical response, remission, and improvements in depressive symptoms following a course of active tDCS are greater in comparison to a course of placebo sham-controlled tDCS. In particular, the largest treatment effects are evident in first episode and recurrent major depression, while minimal effects have been observed in treatment-resistant depression. The proposed mechanism is neuroplasticity at the cellular and molecular level. Alterations in neural responses have been found at the stimulation site as well as subcortically in prefrontal-amygdala connectivity. A possible mediating effect could be cognitive control in emotion dysregulation. Additional beneficial effects on cognitive impairments have been reported, which would address an important unmet need. The tDCS device is portable and can be used at home. Clinical trials are required to establish the efficacy, feasibility and acceptability of home-based tDCS treatment and mechanisms.",
      "authors": [
        "Woodham, Rachel",
        "Rimmer, Rachael M",
        "Mutz, Julian",
        "Fu, Cynthia H Y"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1080/09540261.2021.1879030",
      "keywords": [
        "N neuroplasticity",
        "D016428 Journal Article",
        "N Transcranial direct current stimulation",
        "N tDCS",
        "N neuropsychology",
        "D016454 Review",
        "D013485 Research Support, Non-U.S. Gov't",
        "N major depression",
        "N biomarkers"
      ],
      "number_of_pages": 16,
      "pages": "250-265",
      "publication": {
        "category": "Journal",
        "cite_score": 5.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1369-1627",
        "publisher": "Informa Healthcare",
        "sjr": 1.04,
        "snip": 1.402,
        "subject_areas": [
          "Psychiatry and Mental Health"
        ],
        "title": "International review of psychiatry (Abingdon, England)"
      },
      "publication_date": "2021-03-11",
      "selected": false,
      "title": "Is tDCS a potential first line treatment for major depression?",
      "urls": []
    },
    {
      "abstract": "OBJECTIVE Current analgesic treatments for phantom pain are not optimal. One well-accepted yet limited nonpharmacological option is mirror therapy, which is thought to counterbalance abnormal plasticity. Transcranial direct current stimulation (tDCS) is an emerging approach believed to affect the membrane potential and activity threshold of cortical neurons. tDCS analgesic effectiveness, however, is mild and short, rendering it a noneffective stand-alone treatment. This study aimed to assess if a combination of mirror therapy with tDCS results in a superior analgesic effect as compared with mirror therapy alone in patients suffering from phantom pain due to recent amputation.\nDESIGN Following ethical approval, eligible patients provided informed consent and were randomly assigned to a study treatment group that continued for 2\u00a0weeks (once daily): 1) mirror therapy; 2) mirror therapy and sham tDCS; or 3) mirror therapy and tDCS. Assessments were done before treatment; at the end of treatment weeks 1 and 2; and at 1\u00a0week, 1\u00a0month, and 3\u00a0months following treatment. The primary outcome measure was pain intensity. Secondary measures were derived from the Short Form McGill Pain Questionnaire and the Brief Pain Inventory.\nRESULTS Thirty patients were recruited, and 29 patients completed the study. Three months following treatment, pain intensity was significantly (P<0.001) reduced in the combined treatment group (reduction of 5.4\u00b13.3 points) compared with the other study arms (mirror therapy, 1.2\u00b11.1; mirror therapy and sham tDCS, 2.7\u00b13.2). All secondary outcome results were in line with these findings.\nCONCLUSIONS Combining tDCS with mirror therapy results in a robust long-lasting analgesic effect. These encouraging findings may contribute to the understanding of the underlying mechanisms of phantom pain.",
      "authors": [
        "Segal, Nitza",
        "Pud, Dorit",
        "Amir, Hagai",
        "Ratmansky, Motti",
        "Kuperman, Pora",
        "Honigman, Liat",
        "Treister, Roi"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1093/pm/pnaa388",
      "keywords": [
        "N Transcranial Direct Current Stimulation",
        "N Neuropathic Pain",
        "D016428 Journal Article",
        "N Mirror Therapy",
        "D016449 Randomized Controlled Trial",
        "N Phantom Pain",
        "N Neuromodulation"
      ],
      "number_of_pages": 11,
      "pages": "255-265",
      "publication": {
        "category": "Journal",
        "cite_score": 5.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1526-4637",
        "publisher": "VICER Publishing",
        "sjr": 0.854,
        "snip": 1.207,
        "subject_areas": [
          "Neurology (clinical)",
          "Anesthesiology and Pain Medicine"
        ],
        "title": "Pain medicine (Malden, Mass.)"
      },
      "publication_date": "2021-02-01",
      "selected": false,
      "title": "Additive Analgesic Effect of Transcranial Direct Current Stimulation Together with Mirror Therapy for the Treatment of Phantom Pain.",
      "urls": []
    },
    {
      "abstract": "Experiencing behavioral control over stress can have long-lasting and generalizing effects. Animal research has shown that vmPFC-subcortical interactions are critical for behavioral control; however, research in humans is sparse. Therefore a paradigm was developed in which participants (n = 18) were first assigned to a controllable or uncontrollable version of a signal detection task associated with mild shocks. Subsequently, subjects underwent an fMRI task on the anticipation of speaking in public while measuring self-reported stress, heart rate, and vmPFC network topology. The signal detection task results revealed faster responses to potential shock trials and a trend difference between the controllable and uncontrollable group. The speech anticipation procedure did not show significant between-group differences on self-reported stress or heart rate. fMRI results indicated higher vmPFC efficiency in the controllable threat group at baseline and recovery but similar to the uncontrollable group during speech anticipation. The current report establishes the feasibility of the protocol. However, to evaluate the generalization effect of controllability on the behavioral, physiological, and neural levels further, adequately-powered follow-up research is needed. \u00c2\u00a9 2020 The Authors",
      "authors": [
        "Cremers, H.",
        "Keedy, S.",
        "Coccaro, E."
      ],
      "categories": null,
      "citations": 4,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1016/j.pscychresns.2020.111197",
      "keywords": [
        "fMRI",
        "Network analysis",
        "Behavioral control",
        "vmPFC"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 4.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "09254927",
        "publisher": "Elsevier Ireland Ltd",
        "sjr": 0.813,
        "snip": 0.707,
        "subject_areas": [
          "Neuroscience (miscellaneous)",
          "Psychiatry and Mental Health",
          "Radiology, Nuclear Medicine and Imaging"
        ],
        "title": "Psychiatry Research - Neuroimaging"
      },
      "publication_date": "2021-01-30",
      "selected": false,
      "title": "The development of an fMRI protocol to investigate vmPFC network functioning underlying the generalization of behavioral control",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85092938599&origin=inward"
      ]
    },
    {
      "abstract": "Neurofeedback training is a treatment modality of potential use for improving self-regulation skills in autism spectrum disorder (ASD). Multiple studies using neurofeedback to target symptoms of ASD have been reported. These studies differ among themselves in the type of training (e.g., theta-to-beta ratio, coherence, etc.), topography (Cz or Pz), guidance by quantitative EEG (qEEG), and number of sessions (e.g., 20 vs. 30, etc.). In our study, we proposed that prefrontal neurofeedback training would be accompanied by changes in relative power of EEG bands (e.g., 40\u00c2 Hz-centered gamma band) and ratios of individual bands (e.g., theta-to-beta ratio) and changes in autonomic activity. Outcome measures included EEG, autonomic measures (heart rate, heart rate variability [HRV] indexes, respiration rate, and skin conductance level [SCL]), and behavioral ratings by parents/caregivers. In this pilot feasibility study on 14 children with ASD with comorbid ADHD (~10.28\u00c2 years SD\u00c2 =\u00c2 1.93, 3 females), we administered a 24 session-long course of neurofeedback from the AFz site. The protocol used training for wide-band EEG amplitude suppression (\u00e2\u0080\u009cInhibitAll\u00e2\u0080\u009d) with simultaneous upregulation of the index of 40\u00c2 Hz-centered gamma activity. Quantitative EEG (QEEG) analysis at the prefrontal training site was completed for each session of neurofeedback in order to determine the amplitude of the individual bands (delta, theta, alpha, beta, and gamma), the ratio of the EEG bands of interest (e.g., theta-to-beta ratio [TBR]), and relative power of 40\u00c2 Hz-centered gamma across neurofeedback sessions. In this study, we analyzed Aberrant Behavior Checklist (ABC), Social Responsiveness Scale (SRS-2), and Achenbach\u00e2\u0080\u0099s ASEBA ratings by caregivers (pre- and posttreatment). We found a significant reduction in Irritability and Hyperactivity subscales of the ABC, decrease of T-score on SRS-2, and decrease in Attention Deficit scores of the ASEBA posttreatment. Successful neurofeedback sessions were featured by the changes in SCL, decreased HR, increased HRV (reflected in decreased LF/HF ratio of HRV and increased RMSSD of HRV), and decreased respiration rate. Profiles of psychophysiological changes during individual sessions and across the whole course of neurofeedback training showed active engagement of participants during training process, resulting in gradual decrease of anxiety markers across the whole course of experimental intervention using prefrontal neurofeedback training. Future research is needed to assess QEEG changes in other topographies using brain mapping, more prolonged courses, and other outcome measures including clinical behavioral evaluations to judge the clinical utility of prefrontal neurofeedback in children with ASD with co-occurring ADHD. The current series support a need to address various factors affecting outcome of neurofeedback-based intervention, specifically the question of length of treatment. \u00c2\u00a9 2021, Springer Nature Switzerland AG.",
      "authors": [
        "Sokhadze, E.M.",
        "Kelly, D.P.",
        "Lamina, E.",
        "Casanova, M.F."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1007/978-3-030-54564-2_15",
      "keywords": [
        "Attention",
        "Gamma band",
        "Respiration",
        "EEG",
        "Autism spectrum disorder",
        "Social responsiveness",
        "ADHD",
        "Heart rate",
        "Neurofeedback",
        "Aberrant behavior",
        "Skin conductance"
      ],
      "number_of_pages": 29,
      "pages": "311-339",
      "publication": {
        "category": "Book",
        "cite_score": 0.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2627535X",
        "publisher": "Springer Nature Switzerland AG",
        "sjr": 0.813,
        "snip": 0.707,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Neurology",
          "Neurology (clinical)",
          "Sensory Systems",
          "Behavioral Neuroscience"
        ],
        "title": "Contemporary Clinical Neuroscience"
      },
      "publication_date": "2021-01-01",
      "selected": false,
      "title": "Neurofeedback Training with Concurrent Psychophysiological Monitoring in Children with Autism Spectrum Disorder with Comorbid Attention Deficit/Hyperactivity Disorder",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85114219723&origin=inward"
      ]
    },
    {
      "abstract": "The experiment was aimed to compare the effects of different forms of rehabilitation applied in patients with schizophrenia. Verification of the obtained results was based on the analysis of the level of cognitive and social functioning of the subjects. For this purpose, the following clinical tools were used: Positive and Negative Syndrome Scale (PANSS), Beck Cognitive Insight Scale (BCIS), Color Trial Test (CTT-1, CTT-2), d2 psychological tests, Acceptance of Illness Scale (AIS), Self-efficacy Scale (GSES), Quantitative Electroencephalogram Biofeedback (QEEG-BF), auditory event-related potentials (ERPs), and serum levels of brain-derived neurotrophic factor (BDNF). The subjects were mentally stable male schizophrenia patients who had been in remission. They were divided into two groups which received different types of rehabilitation for three months. Group 1 patients followed a standard rehabilitation and Group 2 patients received GSR Biofeedback (galvanic skin response Biofeedback, GSR-BF) training. Pretherapy and posttherapy measurements were made for each group. Experimental rehabilitation based on GSR-BF training resulted in regulatory control of neurophysiological mechanisms, and the parameters obtained demonstrated improvement in the subjects' cognitive and social function. The following therapy outcomes were observed: (1) reduce psychopathological symptoms (2) improving cognitive (concentration, attention) and social functions (3) increase in the neurotrophic factor BDNF. GSR-BF can be used as an alternative to conventional rehabilitation in schizophrenia patients. Copyright \u00c2\u00a9 2021 Renata Markiewicz and Beata Dobrowolska. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.",
      "authors": [
        "Markiewicz, R.",
        "Dobrowolska, B."
      ],
      "categories": null,
      "citations": 6,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1155/2021/8030485",
      "keywords": [],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 5.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "23146133",
        "publisher": "Hindawi Publishing Corporation",
        "sjr": 0.64,
        "snip": 0.965,
        "subject_areas": [
          "Biochemistry, Genetics and Molecular Biology (all)",
          "Immunology and Microbiology (all)"
        ],
        "title": "BioMed Research International"
      },
      "publication_date": "2021-01-01",
      "selected": false,
      "title": "Reinforcement of self-regulated brain activity in schizophrenia patients undergoing rehabilitation",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85104451698&origin=inward"
      ]
    },
    {
      "abstract": "Background: We previously showed the efficacy of bi-anodal transcranial direct current stimulation (tDCS) over the prefrontal cortex (PFC) regions with extracephalic reference placement in improving negative symptoms in schizophrenia. In this ancillary investigation, the effects of this intervention on insight levels, other clinical outcomes, and cardio-respiratory and autonomic functions were examined and the potential of biomarkers for treatment response was explored. Methods: Schizophrenia patients were randomly allocated to receive 10 sessions of bi-anodal tDCS over the PFC regions with extracephalic reference placement (2 mA, 20 minutes, twice daily for 5 weeks) or sham stimulation. We examined, in 60 patients at baseline, immediately after stimulation and at follow-up visits, the insight levels, other clinical outcomes, blood pressure, respiratory rate, heart rate, and heart rate variability. Results: Insight levels as assessed by the abbreviated version of the Scale to Assess Unawareness in Mental Disorder in schizophrenia awareness of the disease, positive and negative symptoms dimensions, and beliefs about medication compliance as assessed by Medication Adherence Rating Scale were significantly enhanced by active stimulation relative to sham. No effects were observed on cognitive insight, other clinical outcomes, or cardio-respiratory and autonomic functions. Heart rate variability indices as biomarkers were not associated with the clinical response to the intervention. Conclusions: Our results provide evidence for bi-anodal tDCS over the PFC regions with extracephalic reference placement in heightening the levels of insight into the disease and symptoms, as well as beliefs about medication compliance in schizophrenia, without impacting other clinical outcomes and cardio-respiratory/autonomic functions. \u00c2\u00a9 2020 The Author(s) 2020. Published by Oxford University Press on behalf of CINP.",
      "authors": [
        "Chang, C.-C.",
        "Kao, Y.-C.",
        "Chao, C.-Y.",
        "Tzeng, N.-S.",
        "Chang, H.-A."
      ],
      "categories": null,
      "citations": 7,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1093/ijnp/pyaa063",
      "keywords": [
        "impaired insight",
        "extracephalic montage",
        "Schizophrenia",
        "prefrontal cortex",
        "transcranial direct current stimulation"
      ],
      "number_of_pages": 14,
      "pages": "40-53",
      "publication": {
        "category": "Journal",
        "cite_score": 7.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "14611457",
        "publisher": "Oxford University Press",
        "sjr": 1.406,
        "snip": 1.251,
        "subject_areas": [
          "Pharmacology",
          "Psychiatry and Mental Health",
          "Pharmacology (medical)"
        ],
        "title": "International Journal of Neuropsychopharmacology"
      },
      "publication_date": "2021-01-01",
      "selected": false,
      "title": "The Effects of Bi-Anodal tDCS over the Prefrontal Cortex Regions with Extracephalic Reference Placement on Insight Levels and Cardio-Respiratory and Autonomic Functions in Schizophrenia Patients and Exploratory Biomarker Analyses for Treatment Response",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85092895707&origin=inward"
      ]
    },
    {
      "abstract": "n n SIGNIFICANCE STATEMENT The dorsolateral prefrontal cortex (DLPFC) and ventrolateral PFC (VLPFC) are both crucial structures involved in voluntary emotional regulation. However, it remains unclear whether the functions of these two cortical regions that are involved in emotional regulation, which are usually active in non-social situations, could be generalized to the regulation of social pain as well. This study employed transcranial magnetic stimulation (TMS) to examine the causal relationship between the DLPFC/VLPFC and the emotional regulation of social pain via distraction and reappraisal. Ninety human participants (45 males and 45 females) initially underwent either active (DLPFC/VLPFC,  = 30/30) or sham (vertex,  = 30) TMS sessions. Participants were then instructed to use both distraction and reappraisal strategies to downregulate any negative emotions evoked by social exclusion pictures. Convergent results of the subjective emotional rating and electrophysiological indices demonstrated that: (1) both the DLPFC and VLPFC highly facilitate the downregulation of affective responses caused by social exclusion, revealing a causal role of these lateral PFCs in voluntary emotional regulation of both non-social and social pain; and (2) these two cortical regions showed relative functional specificity for distraction (DLPFC) and reappraisal (VLPFC) strategies, which helps to refine the cortical targeting of therapeutic protocols. In addition, the TMS effect was sustainable for at least 1 h, showcasing the potential feasibility of using this method in clinical practice. Together, these findings provide cognitive and neural evidence for the targeting of the VLPFC and/or the DLPFC to improve emotional regulation abilities, especially in social contexts. This study aimed to examine the role of the dorsolateral prefrontal cortex (DLPFC) and ventrolateral PFC (VLPFC) in emotional regulation, particularly in response to social pain through the use of distraction and reappraisal strategies, as this is a relatively underexplored area of inquiry. This study makes a significant contribution to the literature because our results provide novel empirical information on the role of these cortical structures in the processing of negative emotions elicited within certain social contexts. As such, our findings have potential clinical implications, paving the way for future clinicians to be able to accurately target specific brain regions among patients struggling with impaired social cognition abilities, including those diagnosed with posttraumatic stress disorder, autism spectrum disorder, social anxiety disorder, and depression.",
      "authors": [
        "Zhao, Jun",
        "Mo, Licheng",
        "Bi, Rong",
        "He, Zhenhong",
        "Chen, Yuming",
        "Xu, Feng",
        "Xie, Hui",
        "Zhang, Dandan"
      ],
      "categories": null,
      "citations": 49,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1523/JNEUROSCI.1906-20.2020",
      "keywords": [
        "D016428 Journal Article",
        "N TMS",
        "N emotional regulation",
        "D003160 Comparative Study",
        "D013485 Research Support, Non-U.S. Gov't",
        "N social exclusion",
        "N social pain",
        "N dorsolateral prefrontal cortex",
        "N ventrolateral prefrontal cortex"
      ],
      "number_of_pages": 9,
      "pages": "1331-1339",
      "publication": {
        "category": "Journal",
        "cite_score": 9.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1529-2401",
        "publisher": "Society for Neuroscience",
        "sjr": 2.35,
        "snip": 1.471,
        "subject_areas": [
          "Neuroscience (all)"
        ],
        "title": "The Journal of neuroscience : the official journal of the Society for Neuroscience"
      },
      "publication_date": "2020-12-21",
      "selected": false,
      "title": "The VLPFC versus the DLPFC in Downregulating Social Pain Using Reappraisal and Distraction Strategies.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85102074878&origin=inward"
      ]
    },
    {
      "abstract": "Social media revolutionize to exchange of health information. People can easily share and seek information to help them in diagnosing and curing disease. Many scholars have also explored the health information exchange. However, little research focuses on what drives people to adopt health information or recommendation on social media, specifically Instagram. This research explores the phenomenon by utilizing a transactive memory system (TMS) as the primary theoretical lenses. A quantitative survey and analysis were conducted to test several hypotheses developed regarding the phenomenon. The findings showed that social media user acceptance of health information/recommendation was mostly influenced by the communication quality and the credibility of the information. This study also found that communication quality was influenced by two TMS components: specialization and credibility. Furthermore, formal communication was also found to be more influential as the input of TMS compared to informal communication. The implication of the findings is also discussed. \u00c2\u00a9 2020 IEEE.",
      "authors": [
        "Hafizh Rafizal Adnan",
        "Achmad Nizar Hidayanto",
        "Christie Vithasa Immanuel Kassan",
        "Albert Christian Bagun",
        "Ilham Pamungkas Nasution",
        "Samuel",
        "Ervi Cofryanti"
      ],
      "categories": null,
      "citations": 1,
      "comments": null,
      "databases": [
        "IEEE",
        "Scopus"
      ],
      "doi": "10.1109/ICIC50835.2020.9288529",
      "keywords": [
        "health information sharing",
        "partial least squares",
        "transactive memory"
      ],
      "number_of_pages": 7,
      "pages": "1-7",
      "publication": {
        "category": "Conference Proceedings",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": "978-1-7281-8048-9",
        "issn": null,
        "publisher": "IEEE",
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "2020 5th International Conference on Informatics and Computing, ICIC 2020"
      },
      "publication_date": "2020-11-03",
      "selected": false,
      "title": "Social Media User Acceptance on Instagram Health Information Recommendation: A Transactive Memory System Perspective",
      "urls": [
        "https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=9288529",
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85099315612&origin=inward"
      ]
    },
    {
      "abstract": "Objectives To compare cognitive effects and acceptability of repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) in patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI), and to determine whether cognitive training (CT) during rTMS or tDCS provides additional benefits. Methods Electronic search of PubMed, Medline, Embase, the Cochrane Library and PsycINFO up to 5 March 2020. We enrolled double-blind, randomised controlled trials (RCTs). The primary outcomes were acceptability and pre-post treatment changes in general cognition measured by Mini-Mental State Examination, and the secondary outcomes were memory function, verbal fluency, working memory and executive function. Durability of cognitive benefits (1, 2 and \u00e2\u0089\u00a53 months) after brain stimulation was examined. Results We included 27 RCTs (n=1070), and the treatment components included high-frequency rTMS (HFrTMS) and low-frequency rTMS, anodal tDCS (atDCS) and cathodal tDCS (ctDCS), CT, sham CT and sham brain stimulation. Risk of bias of evidence in each domain was low (range: 0%-11.1%). HFrTMS (1.08, 9, 0.35-1.80) and atDCS (0.56, 0.03-1.09) had short-term positive effects on general cognition. CT might be associated with negative effects on general cognition (-0.79,-2.06 to 0.48) during rTMS or tDCS. At 1-month follow-up, HFrTMS (1.65, 0.77-2.54) and ctDCS (2.57, 0.20-4.95) exhibited larger therapeutic responses. Separate analysis of populations with pure AD and MCI revealed positive effects only in individuals with AD. rTMS and tDCS were well tolerated. Conclusions HFrTMS is more effective than atDCS for improving global cognition, and patients with AD may have better responses to rTMS and tDCS than MCI. \u00c2\u00a9 Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.",
      "authors": [
        "Chu, Che-Sheng",
        "Li, Cheng-Ta",
        "Brunoni, Andre R",
        "Yang, Fu-Chi",
        "Tseng, Ping-Tao",
        "Tu, Yu-Kang",
        "Stubbs, Brendon",
        "Carvalho, Andr\u00e9 F",
        "Thompson, Trevor",
        "Rajji, Tarek K",
        "Yeh, Ta-Chuan",
        "Tsai, Chia-Kuang",
        "Chen, Tien-Yu",
        "Li, Dian-Jeng",
        "Hsu, Chih-Wei",
        "Wu, Yi-Cheng",
        "Yu, Chia-Ling",
        "Liang, Chih-Sung"
      ],
      "categories": null,
      "citations": 62,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1136/jnnp-2020-323870",
      "keywords": [],
      "number_of_pages": 9,
      "pages": "195-203",
      "publication": {
        "category": "Journal",
        "cite_score": 15.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1468-330X",
        "publisher": "BMJ Publishing Group",
        "sjr": 3.178,
        "snip": 2.878,
        "subject_areas": [
          "Neurology (clinical)",
          "Psychiatry and Mental Health",
          "Surgery"
        ],
        "title": "Journal of neurology, neurosurgery, and psychiatry"
      },
      "publication_date": "2020-10-28",
      "selected": false,
      "title": "Cognitive effects and acceptability of non-invasive brain stimulation on Alzheimer's disease and mild cognitive impairment: a component network meta-analysis.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85094949660&origin=inward"
      ]
    },
    {
      "abstract": "Abdominal pain in childhood is extremely common and presents frequently to both primary and secondary care, with many children having recurrent pain which impacts on daily functioning. Despite this most children have no discernible underlying pathology. We discuss the underlying mechanism for functional abdominal pain (visceral hypersensitivity), the evidence base linking parental anxiety and patient symptoms, and how parents can be supported in managing their children's symptoms by addressing questions commonly asked by children and families. We look at the evidence for a one-stop rational approach to investigation including a coeliac screen, inflammatory markers and consideration of stool faecal calprotectin, in the absence of red flags. We evaluate commonly used treatments for functional abdominal pain, within a context of managing family expectations. Given the limitations in pharmacological treatment options, trials of probiotics, peppermint oil, mebeverine and (for short-term use only) hyoscine butylbromide may be appropriate. Psychological interventions including cognitive-behavioural therapy, distraction techniques and hypnotherapy have a better evidence base. There is also some evidence for other complementary therapies in children, including yoga and neurostimulation. Outcome is generally good providing there is child and family acceptance of the multiple factors implicated in the aetiology of the pain. \u00c2\u00a9 2020 BMJ Publishing Group. All rights reserved.",
      "authors": [
        "Andrews, E.T.",
        "Beattie, R.M.",
        "Tighe, M.P."
      ],
      "categories": null,
      "citations": 13,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1136/archdischild-2020-318825",
      "keywords": [
        "general paediatrics",
        "gastroenterology",
        "pain"
      ],
      "number_of_pages": 7,
      "pages": "938-944",
      "publication": {
        "category": "Journal",
        "cite_score": 5.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "00039888",
        "publisher": "BMJ Publishing Group",
        "sjr": 1.188,
        "snip": 1.513,
        "subject_areas": [
          "Pediatrics, Perinatology and Child Health"
        ],
        "title": "Archives of Disease in Childhood"
      },
      "publication_date": "2020-10-01",
      "selected": false,
      "title": "Functional abdominal pain: What clinicians need to know",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85081581153&origin=inward"
      ]
    },
    {
      "abstract": "The coding of observational data is commonly used to analyse and evaluate human behaviours. The technique can help researchers inform the design and impact of, for example, an Ubicomp system by studying specific behaviours of interest. There are some tools that can alleviate the burden of observational coding, like those that help to collect and organise data, but can still be error-prone and time-consuming. Moreover, most of these tools lack automation, requiring intense human interaction. In order to mitigate these issues, computer vision (CV) and machine learning (ML) techniques could be used to automate observational coding, but little work has focused on analysing the feasibility of such an approach, with the goal of reducing the total coding time while maintaining accuracy. In this work, we address this question by proposing an automated approach for a real-world case study and compare it to manual coding. The study is composed of 10 videos with an average duration of 17 min each, where the goal is to determine the attention of children with autism that participate in a neurofeedback therapy session. Each video was hand-coded by three human observers to define the ground truth and to measure the manual coding time. Results show that it is feasible to automate the coding of observational behaviours and obtain a noticeable reduction in coding time, but with a slight loss in accuracy. Moreover, we illustrate that the best solution would be a hybrid approach, using a semi-automated system that combines human expertise and ML predictions Keywords Observational studies, Coding behaviours, Automatic coding, Computer-Vision, Machine Learning. \u00c2\u00a9 2020 John Wiley & Sons, Ltd",
      "authors": [
        "L\u00c3\u00b3pez-L\u00c3\u00b3pez, V.R.",
        "Escobedo, L.",
        "Trujillo, L."
      ],
      "categories": null,
      "citations": 1,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1111/exsy.12572",
      "keywords": [
        "automatic behaviour coding",
        "coding behaviours",
        "observational studies",
        "application",
        "machine learning",
        "computer vision",
        "computer Science",
        "human computer interaction",
        "data-driven"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 5.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "02664720",
        "publisher": "Wiley-Blackwell Publishing Ltd",
        "sjr": 0.607,
        "snip": 0.881,
        "subject_areas": [
          "Control and Systems Engineering",
          "Artificial Intelligence",
          "Computational Theory and Mathematics",
          "Theoretical Computer Science"
        ],
        "title": "Expert Systems"
      },
      "publication_date": "2020-10-01",
      "selected": false,
      "title": "Towards an automatic coding of observational studies: Coding neurofeedback therapies of children with autism",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85085604491&origin=inward"
      ]
    },
    {
      "abstract": "IMPORTANCE Tinnitus has a prevalence of 10% to 25% and is frequently associated with numerous complications, such as neuropsychiatric disease. Traditional treatments have failed to meet the needs of patients with tinnitus. Noninvasive brain stimulation (NIBS) can focally modify cortical functioning and has been proposed as a strategy for reducing tinnitus severity. However, the results have been inconclusive.\nOBJECTIVE To evaluate the association between different central NIBS therapies and efficacy and acceptability for treatment of tinnitus.\nDATA SOURCES ClinicalKey, Cochrane CENTRAL, Embase, ProQuest, PubMed, ScienceDirect, and Web of Science databases were searched from inception to August 4, 2019. No language restriction was applied. Manual searches were performed for potentially eligible articles selected from the reference lists of review articles and pairwise meta-analyses.\nSTUDY SELECTION Randomized clinical trials (RCTs) examining the central NIBS method used in patients with unilateral or bilateral tinnitus were included in the current network meta-analysis. The central NIBS method was compared with sham, waiting list, or active controls. Studies that were not clinical trials or RCTs and did not report the outcome of interest were excluded.\nDATA EXTRACTION AND SYNTHESIS Two authors independently screened the studies, extracted the relevant information, and evaluated the risk of bias in the included studies. In cases of discrepancy, a third author became involved. If manuscript data were not available, the corresponding authors or coauthors were approached to obtain the original data. This network meta-analysis was based on the frequentist model.\nMAIN OUTCOMES AND MEASURES The primary outcome was change in the severity of tinnitus. Secondary outcomes were changes in quality of life and the response rate related to the NIBS method in patients with tinnitus.\nRESULTS Overall, 32 unique RCTs were included with 1458 unique participants (mean female proportion, 34.4% [range, 0%-81.2%]; mean age, 49.6 [range, 40.0-62.8] years; median age, 49.8 [interquartile range, 48.1-52.4] years). The results of the network meta-analysis revealed that cathodal transcranial direct current stimulation over the left dorsolateral prefrontal cortex combined with transcranial random noise stimulation over the bilateral auditory cortex was associated with the greatest improvement in tinnitus severity (standardized mean difference [SMD], -1.89; 95% CI, -3.00 to -0.78) and quality of life (SMD, -1.24; 95% CI, -2.02 to -0.45) compared with the controls. Improvement in tinnitus severity ranked more favorably for continuous theta-burst stimulation (cTBS) over both auditory cortices (SMD, -0.79; 95% CI\u2009=\u2009-1.57 to -0.01) than cTBS over only the left auditory cortex (SMD, -0.30; 95% CI, -0.87 to 0.28), compared with controls. Repetitive transcranial magnetic stimulation with priming had a superior beneficial association with tinnitus severity compared with the strategies without priming. None of the investigated NIBS types had a significantly different dropout rate compared with that of the control group.\nCONCLUSIONS AND RELEVANCE This network meta-analysis suggests a potential role of NIBS interventions in tinnitus management. Future large-scale RCTs focusing on longer follow-up and different priming procedure NIBS are warranted to confirm these findings.",
      "authors": [
        "Chen, Jiann-Jy",
        "Zeng, Bing-Syuan",
        "Wu, Ching-Nung",
        "Stubbs, Brendon",
        "Carvalho, Andre F",
        "Brunoni, Andre R",
        "Su, Kuan-Pin",
        "Tu, Yu-Kang",
        "Wu, Yi-Cheng",
        "Chen, Tien-Yu",
        "Lin, Pao-Yen",
        "Liang, Chih-Sung",
        "Hsu, Chih-Wei",
        "Hsu, Shih-Pin",
        "Kuo, Hung-Chang",
        "Chen, Yen-Wen",
        "Tseng, Ping-Tao",
        "Li, Cheng-Ta"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1001/jamaoto.2020.1497",
      "keywords": [],
      "number_of_pages": 9,
      "pages": "801-809",
      "publication": {
        "category": "Journal",
        "cite_score": 10.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2168-619X",
        "publisher": "American Medical Association",
        "sjr": 1.835,
        "snip": 2.48,
        "subject_areas": [
          "Surgery",
          "Otorhinolaryngology"
        ],
        "title": "JAMA otolaryngology-- head & neck surgery"
      },
      "publication_date": "2020-09-01",
      "selected": false,
      "title": "Association of Central Noninvasive Brain Stimulation Interventions With Efficacy and Safety in Tinnitus Management: A Meta-analysis.",
      "urls": []
    },
    {
      "abstract": "d' d' d' We examine the effect of transcranial direct current stimulation (tDCS) of right superior temporal sulcus (rSTS) in memorization of approach/avoidance relationship-action sentences; for example, \"Alejandro accepted/rejected Marta in his group.\" Sixty-five university students participated in a tDCS study, in which a between-subjects design was adopted. Sixty-four participants were also given the behavioral approach system (BAS) and behavioral inhibition system (BIS) scales. Participants were subjected to 20 min of stimulation: anodal (N = 24), cathodal (N = 21), or sham (N = 20); subsequently, they were given a list of 40 sentences (half approach and half avoidance) and told to try to memorize them. Finally, they performed a changed/same memory task (half the sentences were the \"same\" and half were \"changed\"). Previously, we had examined performance in the memory task without tDCS with another group of participants (N = 20). We found that anodal stimulation improved  index of discriminability (hits-false alarms) compared to sham and cathodal conditions for both approach and avoidance sentences. Moreover, the comparison between anodal and task-alone performance showed that stimulation improved  index of approach sentences more, as task-alone performance showed better discrimination for avoidance than for approach. Likewise, we explored a potential modulation of tDCS effect by (BAS) and (BIS) traits. We found that  index improvement in anodal stimulation condition only benefited low BAS and low BIS participants. Implications of these results are discussed in the context of rSTS function in encoding and memorizing verbally described intentional relationship-actions and the role of individual differences on modulating tDCS effect.",
      "authors": [
        "Marrero, Hip\u00f3lito",
        "Yagual, Sara Nila",
        "Garc\u00eda-Marco, Enrique",
        "G\u00e1mez, Elena",
        "Beltr\u00e1n, David",
        "D\u00edaz, Jose Miguel",
        "Urrutia, Mabel"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3390/brainsci10080497",
      "keywords": [
        "N approach/avoidance intentionality",
        "@UI",
        "N Memory",
        "N tDCS",
        "N relationship action-sentences",
        "N Superior Temporal Sulcus",
        "#text"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 3.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2076-3425",
        "publisher": "Multidisciplinary Digital Publishing Institute (MDPI)",
        "sjr": 0.752,
        "snip": 0.938,
        "subject_areas": [
          "Neuroscience (all)"
        ],
        "title": "Brain sciences"
      },
      "publication_date": "2020-07-29",
      "selected": false,
      "title": "Enhancing Memory for Relationship Actions by Transcranial Direct Current Stimulation of the Superior Temporal Sulcus.",
      "urls": []
    },
    {
      "abstract": "Background: The effects of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI)-neurofeedback on brain activation and behaviors have been studied extensively in the past. More recently, researchers have begun to investigate the effects of functional near-infrared spectroscopy-based neurofeedback (fNIRS-neurofeedback). FNIRS is a functional neuroimaging technique based on brain hemodynamics, which is easy to use, portable, inexpensive, and has reduced sensitivity to movement artifacts. Method: We provide the first systematic review and database of fNIRS-neurofeedback studies, synthesizing findings from 22 peer-reviewed studies (including a total of N = 441 participants; 337 healthy, 104 patients). We (1) give a comprehensive overview of how fNIRS-neurofeedback training protocols were implemented, (2) review the online signal-processing methods used, (3) evaluate the quality of studies using pre-set methodological and reporting quality criteria and also present statistical sensitivity/power analyses, (4) investigate the effectiveness of fNIRS-neurofeedback in modulating brain activation, and (5) review its effectiveness in changing behavior in healthy and pathological populations. Results and discussion: (1\u00e2\u0080\u00932) Published studies are heterogeneous (e.g., neurofeedback targets, investigated populations, applied training protocols, and methods). (3) Large randomized controlled trials are still lacking. In view of the novelty of the field, the quality of the published studies is moderate. We identified room for improvement in reporting important information and statistical power to detect realistic effects. (4) Several studies show that people can regulate hemodynamic signals from cortical brain regions with fNIRS-neurofeedback and (5) these studies indicate the feasibility of modulating motor control and prefrontal brain functioning in healthy participants and ameliorating symptoms in clinical populations (stroke, ADHD, autism, and social anxiety). However, valid conclusions about specificity or potential clinical utility are premature. Conclusion: Due to the advantages of practicability and relatively low cost, fNIRS-neurofeedback might provide a suitable and powerful alternative to EEG and fMRI neurofeedback and has great potential for clinical translation of neurofeedback. Together with more rigorous research and reporting practices, further methodological improvements may lead to a more solid understanding of fNIRS-neurofeedback. Future research will benefit from exploiting the advantages of fNIRS, which offers unique opportunities for neurofeedback research. \u00c2\u00a9 Copyright \u00c2\u00a9 2020 Kohl, Mehler, L\u00c3\u00bchrs, Thibault, Konrad and Sorger.",
      "authors": [
        "Kohl, S.H.",
        "Mehler, D.M.A.",
        "L\u00c3\u00bchrs, M.",
        "Thibault, R.T.",
        "Konrad, K.",
        "Sorger, B."
      ],
      "categories": null,
      "citations": 55,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3389/fnins.2020.00594",
      "keywords": [
        "functional near-infrared spectroscopy",
        "neurofeedback",
        "real-time data analysis",
        "clinical translation",
        "self-regulation",
        "systematic review",
        "brain-computer interfacing"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 6.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "16624548",
        "publisher": "Frontiers Media S.A.",
        "sjr": 1.161,
        "snip": 1.221,
        "subject_areas": [
          "Neuroscience (all)"
        ],
        "title": "Frontiers in Neuroscience"
      },
      "publication_date": "2020-07-21",
      "selected": false,
      "title": "The Potential of Functional Near-Infrared Spectroscopy-Based Neurofeedback\u2014A Systematic Review and Recommendations for Best Practice",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85089237085&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND BACKGROUND Advances in transcranial electrical stimulation (tES) are hampered by the conventional rubber electrodes manually attached to the head with rubber bands. This procedure limits montages to a few electrodes, is error prone with respect to electrode configurations and is burdensome for participants and operators. A newly developed flexible cap with integrated textile stimulation electrodes was compared to the conventional setup of rubber electrodes inserted into sponges fixated by rubber bands, with respect to usability and reliability. Two operators applied both setups to 20 healthy volunteers participating in the study. Electrode position and impedance measures as well as subjective evaluations from participants and operators were obtained throughout the stimulation sessions.\nRESULTS RESULTS Our results demonstrated the superiority of the flexible cap by means of significantly higher electrode configuration reproducibility and a more efficient application. Both, operators and volunteers evaluated the flexible cap as easier to use and more comfortable to wear when compared to the conventional setup.\nCONCLUSION CONCLUSIONS In conclusion, the new cap improves existing and opens new application scenarios for tES.",
      "authors": [
        "Hunold, Alexander",
        "Ortega, Daniela",
        "Schellhorn, Klaus",
        "Haueisen, Jens"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1186/s12938-020-00792-1",
      "keywords": [
        "N Patient comfort",
        "@UI",
        "N Reproducibility",
        "N Electric impedance",
        "N Electrodes",
        "N transcranial Direct Current Stimulation",
        "#text",
        "N transcranial Electrical Stimulation"
      ],
      "number_of_pages": null,
      "pages": "50",
      "publication": {
        "category": "Journal",
        "cite_score": 7.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1475-925X",
        "publisher": "BioMed Central Ltd.",
        "sjr": 0.663,
        "snip": 1.31,
        "subject_areas": [
          "Biomaterials",
          "Radiological and Ultrasound Technology",
          "Biomedical Engineering",
          "Radiology, Nuclear Medicine and Imaging"
        ],
        "title": "Biomedical engineering online"
      },
      "publication_date": "2020-06-17",
      "selected": false,
      "title": "Novel flexible cap for application of transcranial electrical stimulation: a usability study.",
      "urls": []
    },
    {
      "abstract": "Trial registration: Up to 80% of people who experience a right-hemisphere stroke suffer from hemispatial neglect. This syndrome is debilitating and impedes rehabilitation. We carried out a clinical feasibility trial of transcranial direct current stimulation (tDCS) and a behavioural rehabilitation programme, alone or in combination, in patients with neglect. Patients >4 weeks post right hemisphere stroke were randomized to 10 sessions of tDCS, 10 sessions of a behavioural intervention, combined intervention, or a control task. Primary outcomes were recruitment and retention rates, with secondary outcomes effect sizes on measures of neglect and quality of life, assessed directly after the interventions, and at 6 months follow up. Of 288 confirmed stroke cases referred (representing 7% of confirmed strokes), we randomized 8% (0.6% of stroke cases overall). The largest number of exclusions (91/288 (34%)) were due to medical comorbidities that prevented patients from undergoing 10 intervention sessions. We recruited 24 patients over 29 months, with 87% completing immediate post-intervention and 67% 6 month evaluations. We established poor feasibility of a clinical trial requiring repeated hospital-based tDCS within a UK hospital healthcare setting, either with or without behavioural training, over a sustained time period. Future trials should consider intensity, duration and location of tDCS neglect interventions. ClinicalTrials.gov identifier: NCT02401724.",
      "authors": [
        "Learmonth, Gemma",
        "Benwell, Christopher S Y",
        "M\u00e4rker, Gesine",
        "Dascalu, Diana",
        "Checketts, Matthew",
        "Santosh, Celestine",
        "Barber, Mark",
        "Walters, Matthew",
        "Muir, Keith W",
        "Harvey, Monika"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1080/09602011.2020.1767161",
      "keywords": [
        "N Transcranial direct current stimulation (tDCS)",
        "D016428 Journal Article",
        "N Hemispatial neglect",
        "D016449 Randomized Controlled Trial",
        "N Non-invasive brain stimulation",
        "N Stroke",
        "N Prospective randomized open blinded end-point (PROBE) trial"
      ],
      "number_of_pages": 27,
      "pages": "1163-1189",
      "publication": {
        "category": "Journal",
        "cite_score": 6.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1464-0694",
        "publisher": "Taylor and Francis Ltd.",
        "sjr": 0.818,
        "snip": 1.563,
        "subject_areas": [
          "Arts and Humanities (miscellaneous)",
          "Applied Psychology",
          "Rehabilitation",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Neuropsychological rehabilitation"
      },
      "publication_date": "2020-06-05",
      "selected": false,
      "title": "Non-invasive brain stimulation in Stroke patients (NIBS): A prospective randomized open blinded end-point (PROBE) feasibility trial using transcranial direct current stimulation (tDCS) in post-stroke hemispatial neglect.",
      "urls": []
    },
    {
      "abstract": "METHOD We collected 130 short semi-structured interviews following treatment sessions from 30 participants with ADHD receiving NF using slow cortical potential training (SCP). The interviews were transcribed verbatim and analyzed using thematic analysis. Themes where evaluated for changes over-time and between participants with high/low treatment compliance. Interviews from 14 participants who had undergone at least five completed interviews were examined in more depths, aiming to establish typical strategy/training profiles.\nRESULTS We identified 16 strategies covering four domains: cognitive, physiological, emotional and unspecified. Typical of most strategies were that they served as a vehicle to regulate mental arousal. Overall, no clear patterns of changes over time were found. Highly compliant participants reported to use the strategies from the emotional domain and the strategy focus more frequently than neutral compliant participants did, while neutral compliant participants reported the use of the strategies muscular activity and passivity more often than participants did with high compliance. Across participants, three strategy profiles were derived, those who handled the task by manipulating their state of mind in relation to the NF task, those who were mainly manifest and concrete towards the task, and those who were mostly unaware of what they were doing. These profiles differed in self-regulatory performance, and only participants showing the state of mind profile experienced a decrease of ADHD symptoms accompanied by objectively measured improvements in self-regulation. In addition, compliance affected both how and what strategies were used.\nCONCLUSION/DISCUSSION A heterogeneous array of cognitive and other strategies is used at varying levels of training compliance by participants with ADHD during SCP that could be condensed to three prototypical profiles. Future research should take compliance and strategy/training profiles into account when evaluating NF. The latter may help to clarify which and how brain activity regulating mechanisms drive training, individual response to NF, and how they are influenced by motivational factors. Our findings might also help to facilitate more effective instructions in how to approach SCP in clinical practice.",
      "authors": [
        "Hasslinger, John",
        "D'Agostini Souto, Manoela",
        "Folkesson Hellstadius, Lisa",
        "B\u00f6lte, Sven"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1371/journal.pone.0233343",
      "keywords": [],
      "number_of_pages": null,
      "pages": "e0233343",
      "publication": {
        "category": "Journal",
        "cite_score": 6.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1932-6203",
        "publisher": "Public Library of Science",
        "sjr": 0.885,
        "snip": 1.253,
        "subject_areas": [
          "Multidisciplinary"
        ],
        "title": "PloS one"
      },
      "publication_date": "2020-06-04",
      "selected": false,
      "title": "Neurofeedback in ADHD: A qualitative study of strategy use in slow cortical potential training.",
      "urls": []
    },
    {
      "abstract": "Stimulant medication and behaviour therapy are the most often applied and accepted treatments for Attention-Deficit/Hyperactivity-Disorder (ADHD). Here we explore where the non-pharmacological clinical intervention known as neurofeedback (NFB), fits on the continuum of empirically supported treatments, using standard protocols. In this quantitative review we utilized an updated and stricter version of the APA guidelines for rating 'well-established' treatments and focused on efficacy and effectiveness using effect-sizes (ES) and remission, with a focus on long-term effects. Efficacy and effectiveness are compared to medication and behaviour therapy using benchmark studies. Only recent systematic reviews and meta-analyses as well as multi-centre randomized controlled trials (RCT's) will be included. Two meta-analyses confirmed significant efficacy of standard neurofeedback protocols for parent and teacher rated symptoms with a medium effect size, and sustained effects after 6-12\u00a0months. Four multicenter RCT's demonstrated significant superiority to semi-active control groups, with medium-large effect sizes end of treatment or follow-up and remission rates of 32-47%. Effectiveness in open-label studies was confirmed, no signs of publication bias were found and no significant neurofeedback-specific side effects have been reported. Standard neurofeedback protocols in the treatment of ADHD can be concluded to be a well-established treatment with medium to large effect sizes and 32-47% remission rates and sustained effects as assessed after 6-12\u00a0months.",
      "authors": [
        "Arns, Martijn",
        "Clark, C Richard",
        "Trullinger, Mark",
        "deBeus, Roger",
        "Mack, Martha",
        "Aniftos, Michelle"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1007/s10484-020-09455-2",
      "keywords": [
        "N Effect size",
        "N Remission",
        "D016428 Journal Article",
        "D016454 Review",
        "N Neurofeedback",
        "N Review",
        "N ADHD"
      ],
      "number_of_pages": 10,
      "pages": "39-48",
      "publication": {
        "category": "Journal",
        "cite_score": 5.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1573-3270",
        "publisher": "Springer New York",
        "sjr": 0.534,
        "snip": 1.182,
        "subject_areas": [
          "Applied Psychology",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Applied psychophysiology and biofeedback"
      },
      "publication_date": "2020-06-01",
      "selected": false,
      "title": "Neurofeedback and Attention-Deficit/Hyperactivity-Disorder (ADHD) in Children: Rating the Evidence and Proposed Guidelines.",
      "urls": []
    },
    {
      "abstract": "The aim of this pilot study was to analyse the influence of Galvanic Skin Response (GSR) Biofeedback training in a group of 18 men with schizophrenia at the remission stage. The results were verified according to: Positive and Negative Syndrome Scale (PANSS), Acceptance of Illness Scale (AIS), Self-efficacy Scale (GSES), Beck Cognitive Insight Scale (BCIS) scales, Colour Trial Test (CTT-1, CTT-2), d2 psychological tests, Quantitative Electroencephalogram (QEEG) Biofeedback, auditory event-related potentials (ERPs), and serum levels of brain-derived neurotrophic factor (BDNF). The results were compared in the same patients after 3 months. Statistically significant changes were noted in results for the variables on the PANSS scale. For the BDNF variable, a statistically significant increase occurred, indicating that GSR Biofeedback training may influence serum levels of the neurotrophic factor. Statistically significant changes were noted in results for the variables on the BCIS, AIS, and GSES indicating an improvement in the cognitive and social functioning. Changes were noted for results for theta/beta and theta/Sensory Motor Rhythm (SMR) ratios, which indicate an improvement in concentration and attention. Changes were noted for the N1 wave amplitude in the frontal brain region (F-z), and for the P2 wave latency in the central brain region (C-z), which indicates an improvement in the initial perceptual analysis. The use of GSR Biofeedback in a group of patients with schizophrenia gives interesting results, but requires further in-depth research. \u00c2\u00a9 2020 by the authors. Licensee MDPI, Basel, Switzerland.",
      "authors": [
        "Markiewicz, R.",
        "Dobrowolska, B."
      ],
      "categories": null,
      "citations": 8,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3390/ijerph17114034",
      "keywords": [
        "Serum neurotrophic factor (BDNF)",
        "Schizophrenia",
        "QEEG Biofeedback",
        "Event-related potentials (ERP)"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 5.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "16617827",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.828,
        "snip": 1.28,
        "subject_areas": [
          "Pollution",
          "Public Health, Environmental and Occupational Health",
          "Health, Toxicology and Mutagenesis"
        ],
        "title": "International Journal of Environmental Research and Public Health"
      },
      "publication_date": "2020-06-01",
      "selected": false,
      "title": "Cognitive and social rehabilitation in schizophrenia\u2014from neurophysiology to neuromodulation. Pilot study",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85086151729&origin=inward"
      ]
    },
    {
      "abstract": "Deception scholars have argued that increasing the liar's cognitive system artificially can produce deception cues. However, if too much load is imposed, the truth tellers' performance can also be impaired. To address this issue, we designed a veracity task that incorporated a secondary task to increase cognitive load gradually. Also, because deception has been associated with activity in the inferior frontal cortex (IFC), we examined the influence of transcranial direct current stimulation (tDCS) of the IFC on performance. During stimulation, participants truthfully or deceptively indicated whether each of a number of statements shown on screen was true or not. Higher load decreased recall but not general compliance or response times (RTs). Truthful trials yielded higher compliance rates and faster RTs than deceptive trials except for the highest load level. Anodal right stimulation decreased compliance in truthful trials when participants were not overloaded. Truth telling was more vulnerable to cognitive load and tDCS than lying.",
      "authors": [
        "S\u00e1nchez, Nuria",
        "Masip, Jaume",
        "G\u00f3mez-Ariza, Carlos J"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3389/fpsyg.2020.00776",
      "keywords": [
        "N inhibitory control",
        "@UI",
        "N inferior frontal cortex",
        "N cognitive load",
        "N transcranial direct current stimulation",
        "#text",
        "N deception"
      ],
      "number_of_pages": null,
      "pages": "776",
      "publication": {
        "category": "Journal",
        "cite_score": 4.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1664-1078",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.891,
        "snip": 1.422,
        "subject_areas": [
          "Psychology (all)"
        ],
        "title": "Frontiers in psychology"
      },
      "publication_date": "2020-05-19",
      "selected": false,
      "title": "Both High Cognitive Load and Transcranial Direct Current Stimulation Over the Right Inferior Frontal Cortex Make Truth and Lie Responses More Similar.",
      "urls": []
    },
    {
      "abstract": "Objectives: Little is known about the impact of fronto-temporal transcranial direct current stimulation (tDCS) on attitudes toward mental illness, psychosocial and autonomic functioning, life quality, and medication adherence among schizophrenia patients. Methods: Sixty schizophrenia patients were randomly allocated to receive 10 sessions of active (2 mA, 20 min, 2 sessions/day for five weekdays) or sham fronto-temporal tDCS. Self-Appraisal of Illness Questionnaire (SAIQ), Medication Adherence Rating Scale (MARS), World Health Organization Quality of Life-BREF (WHOQOL-BREF) and indices of heart rate variability (HRV) were measured at baseline, immediately after tDCS and at one-month follow-up visit. Results: There were significant group-by-time interactions for scores of SAIQ presence/outcome subscale, total MARS and its subscale of subjective response to taking medication, WHOQOL-BREF psychological domain. Relative to sham, tDCS significantly improved self-awareness of presence/outcome of schizophrenia (Cohen's d = 0.465, p = 0.0011), subjective response to taking medication (Cohen's d = 0.639, p < 0.001) and psychological domain of life quality (Cohen's d = 0.459, p = 0.00114). These effects lasted for less than one month. The group-by-time interactions were non-significant for clinician-rated psychosocial functioning, mean RR intervals, and all HRV indices. Conclusion: Fronto-temporal tDCS briefly optimizes self-reported insight levels, beliefs about treatment adherence, and psychological domain of life quality in patients with schizophrenia. Further studies are required to confirm whether patients treated with 5-day, 10-session tDCS in combination with multisession \u00e2\u0080\u009cmaintenance\u00e2\u0080\u009d stimulation every month would attain favourable outcomes. Significance: We provide novel evidence for the potential utility of tDCS in schizophrenia. \u00c2\u00a9 2020 International Federation of Clinical Neurophysiology",
      "authors": [
        "Kao, Yu-Chen",
        "Tzeng, Nian-Sheng",
        "Chao, Che-Yi",
        "Chang, Chuan-Chia",
        "Chang, Hsin-An"
      ],
      "categories": null,
      "citations": 14,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1016/j.clinph.2020.02.029",
      "keywords": [
        "N Treatment adherence",
        "D016428 Journal Article",
        "N Transcranial direct current stimulation",
        "N Schizophrenia",
        "N Heart rate variability",
        "D013485 Research Support, Non-U.S. Gov't",
        "D016449 Randomized Controlled Trial",
        "N Life quality",
        "N Self-appraisal of illness"
      ],
      "number_of_pages": 11,
      "pages": "1997-2007",
      "publication": {
        "category": "Journal",
        "cite_score": 7.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1872-8952",
        "publisher": "Elsevier Ireland Ltd",
        "sjr": 1.212,
        "snip": 1.482,
        "subject_areas": [
          "Physiology (medical)",
          "Sensory Systems",
          "Neurology (clinical)",
          "Neurology"
        ],
        "title": "Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology"
      },
      "publication_date": "2020-04-02",
      "selected": false,
      "title": "Modulation of self-appraisal of illness, medication adherence, life quality and autonomic functioning by transcranial direct current stimulation in schizophrenia patients.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85083118585&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND There is a need for easy to use, reliable neuromuscular monitors (NMMs). This multicenter, prospective, unblinded study compared the discomfort associated with neurostimulation in unmedicated healthy volunteers when using the new electromyography (EMG)-based TetraGraph and acceleromyography (AMG)-based TOF-Watch NMMs. The secondary aim was to compare the repeatability of the train-of-four (TOF) ratios (TOFRs) obtained with the 2 devices.\nMETHODS The TOF measurements of 135 volunteers from 3 university hospitals were analyzed (age: 38.3 \u00b1 12 years [mean \u00b1 standard deviation [SD]]; male/female ratio = 63:72). The left or right ulnar nerve was stimulated at the wrist in TOF mode with 20, 30, 40, and 50 mA stimulating current intensities with both devices in random order. The TOF-Watch used standard electrocardiography (ECG) electrodes (Red Dot; 3M Health Care) for nerve stimulation. The stimulating surface area of 1 ECG electrode is 113 mm. The piezoelectric probe was attached to the thumb, and a hand adapter was used to ensure consistency of AMG measurements. The TetraGraph uses proprietary surface strip electrodes for nerve stimulation and muscle action potential recording, whose stimulating surface area is roughly twice as big as that of standard ECG electrodes (228.5 mm). The volunteers were asked to rate the discomfort associated with neurostimulation on a 0-10 verbal numerical rating scale (VNRS) score anchored with 0 (no pain) and 10 (worst pain ever experienced). A linear mixed-effects model was used to evaluate the difference in VNRS scores between devices. P <.05 was accepted as the level of significance.\nRESULTS In the linear mixed-effects model, there were no differences in VNRS scores between devices at any of the stimulating current intensities, P = .38. The median (range) VNRS scores obtained with TOF-Watch and TetraGraph devices were 2 (0-7) vs 2 (0-8) at 20 mA, 3 (1-9) vs 3 (1-9) at 30 mA, 5 (1-10) vs 5 (1-10) at 40 mA, and 5 (1-10) vs 6 (1-10) at 50 mA stimulating current intensities. The mean of the 1469 TOFRs obtained with TetraGraph was 100.43% \u00b1 7.74% (standard error = 0.2%). Due to technical difficulties, the repeatability of the TOFRs could not be determined.\nCONCLUSIONS Despite the different size and design of the stimulating electrodes, the 2 NMMs caused the same level of discomfort in unmedicated healthy volunteers.",
      "authors": [
        "Nemes, R\u00e9ka",
        "Nagy, Gy\u00f6rgy",
        "Murphy, Glenn S",
        "Logvinov, Ilana I",
        "F\u00fclesdi, B\u00e9la",
        "Renew, J Ross"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1213/ANE.0000000000004326",
      "keywords": [],
      "number_of_pages": 8,
      "pages": "941-948",
      "publication": {
        "category": "Journal",
        "cite_score": 8.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1526-7598",
        "publisher": "Lippincott Williams and Wilkins Ltd.",
        "sjr": 1.365,
        "snip": 1.78,
        "subject_areas": [
          "Anesthesiology and Pain Medicine"
        ],
        "title": "Anesthesia and analgesia"
      },
      "publication_date": "2020-04-01",
      "selected": false,
      "title": "Awake Volunteer Pain Scores During Neuromuscular Monitoring.",
      "urls": []
    },
    {
      "abstract": "Schizophrenia (SCZ) is a neurodevelopmental disorder characterized by positive symptoms (hallucinations and delusions), negative symptoms (anhedonia, social withdrawal) and marked cognitive deficits (memory, executive function, and attention). Current mainstays of treatment, including medications and psychotherapy, do not adequately address cognitive symptoms, which are essential for everyday functioning. However, recent advances in computational neurobiology have rekindled interest in neurofeedback (NF), a form of self-regulation or neuromodulation, in potentially alleviating cognitive symptoms in patients with SCZ. Therefore, we conducted a systematic review of the literature for NF studies in SCZ to identify lessons learned and to identify steps to move the field forward. Our findings reveal that NF studies to date consist mostly of case studies and small sample, single-group studies. Despite few randomized clinical trials, the results suggest that NF is feasible and that it leads to measurable changes in brain function. These findings indicate early proof-of-concept data that needs to be followed up by larger, randomized clinical trials, testing the efficacy of NF compared to well thought out placebos. We hope that such an undertaking by the field will lead to innovative solutions that address refractory symptoms and improve everyday functioning in patients with SCZ.",
      "authors": [
        "Gandara, Veronica",
        "Pineda, Jaime A",
        "Shu, I-Wei",
        "Singh, Fiza"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1093/schizbullopen/sgaa005",
      "keywords": [
        "D016428 Journal Article",
        "N schizophrenia",
        "N rt-fMRI",
        "N self-regulation",
        "N neurofeedback",
        "D016454 Review",
        "D016420 Comment",
        "N EEG",
        "N treatment refractory"
      ],
      "number_of_pages": null,
      "pages": "sgaa005",
      "publication": {
        "category": "Journal",
        "cite_score": 1.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2632-7899",
        "publisher": "Oxford University Press",
        "sjr": 0.635,
        "snip": 0.713,
        "subject_areas": [
          "Psychiatry and Mental Health"
        ],
        "title": "Schizophrenia bulletin open"
      },
      "publication_date": "2020-03-02",
      "selected": false,
      "title": "A Systematic Review of the Potential Use of Neurofeedback in Patients With Schizophrenia.",
      "urls": []
    },
    {
      "abstract": "Electro-stimulation or modulation of deep brain regions is commonly used in clinical procedures for the treatment of several nervous system disorders. In particular, transcranial direct current stimulation (tDCS) is widely used as an affordable clinical application that is applied through electrodes attached to the scalp. However, it is difficult to determine the amount and distribution of the electric field (EF) in the different brain regions due to anatomical complexity and high inter-subject variability. Personalized tDCS is an emerging clinical procedure that is used to tolerate electrode montage for accurate targeting. This procedure is guided by computational head models generated from anatomical images such as MRI. Distribution of the EF in segmented head models can be calculated through simulation studies. Therefore, fast, accurate, and feasible segmentation of different brain structures would lead to a better adjustment for customized tDCS studies. In this study, a single-encoder multi-decoders convolutional neural network is proposed for deep brain segmentation. The proposed architecture is trained to segment seven deep brain structures using T1-weighted MRI. Network generated models are compared with a reference model constructed using a semi-automatic method, and it presents a high matching especially in Thalamus (Dice Coefficient (DC) = 94.70%), Caudate (DC = 91.98%) and Putamen (DC = 90.31%) structures. Electric field distribution during tDCS in generated and reference models matched well each other, suggesting its potential usefulness in clinical practice.",
      "authors": [
        "Rashed, Essam A",
        "Gomez-Tames, Jose",
        "Hirata, Akimasa"
      ],
      "categories": null,
      "citations": null,
      "comments": "To appear in Neural Networks",
      "databases": [
        "PubMed",
        "arXiv"
      ],
      "doi": "10.1016/j.neunet.2020.02.006",
      "keywords": [
        "@UI",
        "N tDCS",
        "N Brain stimulation",
        "N MRI",
        "N End-to-end semantic segmentation",
        "#text",
        "N Convolutional neural network"
      ],
      "number_of_pages": 12,
      "pages": "233-244",
      "publication": {
        "category": "Journal",
        "cite_score": 14.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1879-2782",
        "publisher": "Elsevier Ltd.",
        "sjr": 2.221,
        "snip": 2.729,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Image and Video Processing",
          "Learning",
          "Neurons and Cognition",
          "Artificial Intelligence"
        ],
        "title": "Neural networks : the official journal of the International Neural Network Society"
      },
      "publication_date": "2020-02-25",
      "selected": false,
      "title": "End-to-end semantic segmentation of personalized deep brain structures for non-invasive brain stimulation.",
      "urls": [
        "http://arxiv.org/pdf/2002.05487v1",
        "http://dx.doi.org/10.1016/j.neunet.2020.02.006",
        "http://arxiv.org/abs/2002.05487v1"
      ]
    },
    {
      "abstract": "The relationship between tDCS (transcranial direct current stimulation) and its influence on glycemia has been the aim of limited research efforts. Usually, the focus has been set on lowering the blood sugar level or interference with insulin resistance, but also the treatment of diabetic polyneuropathy and pain management. In this case report, we outline the development of hyperglycemia and the following onset of type I diabetes during a series of tDCS in a 24-year old Caucasian female patient treated with our research protocol (10 sessions; 2 mA; 30 min; the anode over F3; the cathode over Fp2) for anorexia nervosa. \u00c2\u00a9 Copyright \u00c2\u00a9 2020 Mares, Ceresnakova, Albrecht, Buday, Klasova, Horackova, Raboch, Papezova and Anders.",
      "authors": [
        "Mares, T.",
        "Ceresnakova, S.",
        "Albrecht, J.",
        "Buday, J.",
        "Klasova, J.",
        "Horackova, K.",
        "Raboch, J.",
        "Papezova, H.",
        "Anders, M."
      ],
      "categories": null,
      "citations": 3,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3389/fpsyt.2020.00040",
      "keywords": [
        "type 1 diabetes",
        "insulin resistance",
        "anorexia nervosa",
        "adverse effect",
        "transcranial direct current stimulation"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Frontiers in Psychiatry"
      },
      "publication_date": "2020-02-13",
      "selected": false,
      "title": "The Onset of Diabetes During Transcranial Direct Current Stimulation Treatment of Anorexia Nervosa \u2014 A Case Report",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85081707862&origin=inward"
      ]
    },
    {
      "abstract": "The Barcelona Brain Health Initiative is a longitudinal cohort study that began in 2017 and aims to understand and characterize the determinants of brain health maintenance in middle aged adults. A cohort of 4686 individuals between the ages of 40 and 65 years free from any neurological or psychiatric diseases was established, and we collected extensive demographic, socio-economic information along with measures of self-perceived health and lifestyles (general health, physical activity, cognitive activity, socialization, sleep, nutrition and vital plan). Here we report on the baseline characteristics of the participants, and the results of the one-year follow-up evaluation. Participants were mainly women, highly educated, and with better lifestyles compared with the general population. After one year 60% of participants completed the one-year follow-up, and these were older, with higher educational level and with better lifestyles in some domains. In the absence of any specific interventions to-date, these participants showed small improvements in physical activity and sleep, but decreased adherence to a Mediterranean diet. These changes were negatively associated with baseline scores, and poorer habits at baseline were predictive of an improvement in lifestyle domains. Of the 2353 participants who completed the one-year follow-up, 73 had been diagnosed with new neurological and neuropsychiatric diseases. Changes in vital plan at follow-up, as well as gender, sleep quality and sense of coherence at baseline were shown to be significant risk factors for the onset of these diagnoses. Notably, gender risk factor decreased in importance as we adjusted by sleep habits, suggesting its potential mediator effects. These findings stress the importance of healthy lifestyles in sustaining brain health, and illustrate the individual benefit that can be derived from participation in longitudinal observational studies. Modifiable lifestyles, specifically quality of sleep, may partially mediate the effect of other risk factors in the development of some neuropsychiatric conditions.",
      "authors": [
        "Cattaneo, Gabriele",
        "Bartr\u00e9s-Faz, David",
        "Morris, Timothy P",
        "Solana S\u00e1nchez, Javier",
        "Maci\u00e0, D\u00eddac",
        "Tormos, Josep M",
        "Pascual-Leone, Alvaro"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1371/journal.pone.0228754",
      "keywords": [],
      "number_of_pages": null,
      "pages": "e0228754",
      "publication": {
        "category": "Journal",
        "cite_score": 6.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1932-6203",
        "publisher": "Public Library of Science",
        "sjr": 0.885,
        "snip": 1.253,
        "subject_areas": [
          "Multidisciplinary"
        ],
        "title": "PloS one"
      },
      "publication_date": "2020-02-11",
      "selected": false,
      "title": "The Barcelona Brain Health Initiative: Cohort description and first follow-up.",
      "urls": []
    },
    {
      "abstract": "BACKGROUND Transcranial direct current stimulation (tDCS) is a method of noninvasive neuromodulation and potential therapeutic tool to improve functioning and relieve symptoms across a range of central and peripheral nervous system conditions. Evidence suggests that the effects of tDCS are cumulative with consecutive daily applications needed to achieve clinically meaningful effects. Therefore, there is growing interest in delivering tDCS away from the clinic or research facility, usually at home.\nOBJECTIVE To provide a comprehensive guide to operationalize safe and responsible use of tDCS in home settings for both investigative and clinical use.\nMETHODS Providing treatment at home can improve access and compliance by decreasing the burden of time and travel for patients and their caregivers, as well as to reach those in remote locations and/or living with more advanced disabilities.\nRESULTS To date, methodological approaches for at-home tDCS delivery have varied. After implementing the first basic guidelines for at-home tDCS in clinical trials, this work describes a comprehensive guide for facilitating safe and responsible use of tDCS in home settings enabling access for repeated administration over time.\nCONCLUSION These guidelines provide a reference and standard for practice when employing the use of tDCS outside of the clinic setting.",
      "authors": [
        "Charvet, Leigh E",
        "Shaw, Michael T",
        "Bikson, Marom",
        "Woods, Adam J",
        "Knotkova, Helena"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.brs.2020.02.011",
      "keywords": [
        "N Remotely supervised tDCS",
        "N Transcranial direct current stimulation (tDCS)",
        "@UI",
        "N Best practices in tDCS",
        "N Non-invasive brain stimulation",
        "N tDCS safety guide",
        "#text",
        "N At-home tDCS"
      ],
      "number_of_pages": 8,
      "pages": "686-693",
      "publication": {
        "category": "Journal",
        "cite_score": 12.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1876-4754",
        "publisher": "Elsevier Inc.",
        "sjr": 2.184,
        "snip": 1.816,
        "subject_areas": [
          "Neurology (clinical)",
          "Biophysics",
          "Neuroscience (all)"
        ],
        "title": "Brain stimulation"
      },
      "publication_date": "2020-02-10",
      "selected": false,
      "title": "Supervised transcranial direct current stimulation (tDCS) at home: A guide for clinical research and practice.",
      "urls": []
    },
    {
      "abstract": "Modulating the temporoparietal junction (TPJ), especially the right counterpart, shows promises in enhancing social cognitive ability. However, it is ambiguous whether the functional lateralization of TPJ determines people's responsiveness to brain stimulation. Here, this issue is investigated with an individual difference approach. Forty-five participants attended three sessions of transcranial direct current stimulation (tDCS) experiments and one neuroimaging session. The results support the symmetric mechanism of left and right TPJ stimulation. First, the left and right TPJ stimulation effect are comparable in the group-level analysis. Second, the individual-level analysis reveals that a less right-lateralized TPJ is associated with a higher level of responsiveness. Participants could be classified into positive responders showing cognitive enhancement and negative responders showing cognitive impairment due to stimulation. The positive responders show weaker connectivity between bilateral TPJ and the medial prefrontal cortex, which mediates the prediction of offline responsiveness by the lateralization and the social-related trait. These findings call for a better characterization and predictive models for whom tDCS should be used for, and highlight the necessity and feasibility of prestimulation screening. \u00c2\u00a9 2020 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim",
      "authors": [
        "Yang, Li-Zhuang",
        "Zhang, Wei",
        "Wang, Wenjuan",
        "Yang, Zhiyu",
        "Wang, Hongzhi",
        "Deng, Zhi-De",
        "Li, Chuanfu",
        "Qiu, Bensheng",
        "Zhang, Da-Ren",
        "Kadosh, Roi Cohen",
        "Li, Hai",
        "Zhang, Xiaochu"
      ],
      "categories": null,
      "citations": 11,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1002/advs.201902863",
      "keywords": [
        "N lateralization",
        "N temporoparietal junction",
        "N tDCS",
        "N neurostimulation",
        "#text",
        "N medial superior frontal gyrus",
        "@UI"
      ],
      "number_of_pages": null,
      "pages": "1902863",
      "publication": {
        "category": "Journal",
        "cite_score": 19.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2198-3844",
        "publisher": "Wiley-VCH Verlag",
        "sjr": 4.086,
        "snip": 2.304,
        "subject_areas": [
          "Biochemistry, Genetics and Molecular Biology (miscellaneous)",
          "Physics and Astronomy (all)",
          "Medicine (miscellaneous)",
          "Engineering (all)",
          "Chemical Engineering (all)",
          "Materials Science (all)"
        ],
        "title": "Advanced science (Weinheim, Baden-Wurttemberg, Germany)"
      },
      "publication_date": "2020-01-21",
      "selected": false,
      "title": "Neural and Psychological Predictors of Cognitive Enhancement and Impairment from Neurostimulation.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85078681500&origin=inward"
      ]
    },
    {
      "abstract": "Introduction Workplace violence directed at paramedics by patients and bystanders is a persistent and pervasive issue. There is little available evidence supporting the effectiveness of current interventions in the paramedicine context. No studies have reported on potential barriers and there is little evidence supporting opportunities for more effective interventions. The objective of this study was to make an inventory of current workplace interventions and explore the barriers and opportunities for these interventions as perceived by paramedics. Methods Ten paramedics were interviewed about their experiences and insights into workplace violence. The interview data underwent thematic and narrative analysis. Results Seven interventions were highlighted, 10 barriers and 12 opportunities for current and future workplace violence interventions were discussed. The majority of the barriers related to culture in society, attitudes of staff, and lack of capacity for the ambulance service to take action following violent events. The opportunities raised included co-design of interventions, culture change for paramedics and communities, accountability for paramedics and perpetrators of violence, increased ambulance service options following violent events, and improving feedback to staff. Conclusion The findings of this study suggest that interventions are likely to be more effective and sustainable if they are evidence-based, codesigned, address all levels of healthcare, and evaluated. Important areas for future research include a focus on consequences and accountability for perpetrators and strategies for ambulance services and paramedics to participate in public health approaches to reducing violence in communities. \u00c2\u00a9 2020, Paramedics Australasia. All rights reserved.",
      "authors": [
        "Thomas, B.",
        "O\u00e2\u0080\u0099meara, P.",
        "Edvardsson, K.",
        "Spelten, E."
      ],
      "categories": null,
      "citations": 5,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.33151/ajp.17.817",
      "keywords": [
        "Paramedicine",
        "Emergency medical services",
        "Workplace violence",
        "Occupational injuries",
        "Policy making"
      ],
      "number_of_pages": 9,
      "pages": "1-9",
      "publication": {
        "category": "Journal",
        "cite_score": 1.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "22027270",
        "publisher": "Faculty of Health, Engineering and Science, Edith Cowan University",
        "sjr": 0.266,
        "snip": 0.44,
        "subject_areas": [
          "Emergency Nursing",
          "Emergency Medicine",
          "Emergency Medical Services"
        ],
        "title": "Australasian Journal of Paramedicine"
      },
      "publication_date": "2020-01-06",
      "selected": false,
      "title": "Barriers and opportunities for workplace violence interventions in australian paramedicine: A qualitative study",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85091719132&origin=inward"
      ]
    },
    {
      "abstract": "A unique challenge in some brain tumor patients is the fact that tumors arising in certain areas of the brain involve the neural structures of consciousness or alertness, limiting the patient's ability to participate in rehabilitation following surgery. A critical question is whether neurostimulant therapy can help patients participate in rehabilitation efforts. We performed a retrospective review of all patients undergoing brain tumor surgery by the senior author from 2012 to 2018. We limited this study to patients with tumors occupying critical structures related to consciousness, alertness, and motor initiation. A combination of methylphenidate and levodopa/carbidopa was used to monitor the progress of patients through neurorehabilitation efforts. We identified 101 patients who experienced an inability to participate in rehabilitation (ITPR) in the post-operative period. Of these, 86 patients (85%) were treated with methylphenidate and levodopa/carbidopa. Cases of ITPR were related to dysfunction of the brainstem (12/86 cases, 14%), thalamus (17/86 cases, 20%), hypothalamus (14/86 cases, 16%), basal ganglia (13/86 cases, 15%), and medial frontal lobe (30/86 cases, 35%). Of the 86 individuals treated, 47/86 patients (55%) showed early improvement in their ability to participate with rehabilitation. At three month follow-up, 58/86 patients (67%) had returned to living independently or were at least interactive and cooperative during follow-up examination. This feasibility report suggests that combined therapy with methylphenidate and levodopa/carbidopa may help patients participate in neurorehabilitation efforts in the immediate post-operative period following brain tumor surgery. Randomized, controlled clinical trials are needed to explore this concept more thoroughly. \u00c2\u00a9 2019",
      "authors": [
        "Briggs, R.G.",
        "Ahsan, S.A.",
        "Conner, A.K.",
        "Nix, C.E.",
        "Jacobs, C.C.",
        "Jones, R.G.",
        "Sheets, J.R.",
        "Palejwala, A.H.",
        "Chendeb, K.",
        "Sughrue, M.E."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1016/j.jocn.2019.10.004",
      "keywords": [
        "Neurorehabiliation",
        "Neurotransmitter",
        "Neurostimulation",
        "Brain",
        "Tumor"
      ],
      "number_of_pages": 4,
      "pages": "93-96",
      "publication": {
        "category": "Journal",
        "cite_score": 3.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "09675868",
        "publisher": "Churchill Livingstone",
        "sjr": 0.54,
        "snip": 0.836,
        "subject_areas": [
          "Physiology (medical)",
          "Neurology (clinical)",
          "Neurology",
          "Surgery"
        ],
        "title": "Journal of Clinical Neuroscience"
      },
      "publication_date": "2020-01-01",
      "selected": false,
      "title": "Neurochemical supplementation in patients with depressed levels of participation after brain tumor surgery: Rationale and preliminary results",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85075819774&origin=inward"
      ]
    },
    {
      "abstract": "One of the most important and early impairments in autism spectrum disorder (ASD) is the abnormal visual processing of human faces. This deficit has been associated with hypoactivation of the fusiform face area (FFA), one of the main hubs of the face-processing network. Neurofeedback based on real-time fMRI (rtfMRI-NF) is a technique that allows the self-regulation of circumscribed brain regions, leading to specific neural modulation and behavioral changes. The aim of the present study was to train participants with ASD to achieve up-regulation of the FFA using rtfMRI-NF, to investigate the neural effects of FFA up-regulation in ASD. For this purpose, three groups of volunteers with normal I.Q. and fluent language were recruited to participate in a rtfMRI-NF protocol of eight training runs in 2 days. Five subjects with ASD participated as part of the experimental group and received contingent feedback to up-regulate bilateral FFA. Two control groups, each one with three participants with typical development (TD), underwent the same protocol: one group with contingent feedback and the other with sham feedback. Whole-brain and functional connectivity analysis using each fusiform gyrus as independent seeds were carried out. The results show that individuals with TD and ASD can achieve FFA up-regulation with contingent feedback. RtfMRI-NF in ASD produced more numerous and stronger short-range connections among brain areas of the ventral visual stream and an absence of the long-range connections to insula and inferior frontal gyrus, as observed in TD subjects. Recruitment of inferior frontal gyrus was observed in both groups during FAA up-regulation. However, insula and caudate nucleus were only recruited in subjects with TD. These results could be explained from a neurodevelopment perspective as a lack of the normal specialization of visual processing areas, and a compensatory mechanism to process visual information of faces. RtfMRI-NF emerges as a potential tool to study visual processing network in ASD, and to explore its clinical potential. \u00c2\u00a9 Copyright \u00c2\u00a9 2019 Pereira, Sepulveda, Rana, Montalba, Tejos, Torres, Sitaram and Ruiz.",
      "authors": [
        "Pereira, Jaime A",
        "Sepulveda, Pradyumna",
        "Rana, Mohit",
        "Montalba, Cristian",
        "Tejos, Cristian",
        "Torres, Rafael",
        "Sitaram, Ranganatha",
        "Ruiz, Sergio"
      ],
      "categories": null,
      "citations": 15,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.3389/fnhum.2019.00446",
      "keywords": [
        "@UI",
        "N brain\u2013computer interfaces",
        "N facial processing",
        "N neurofeedback",
        "N real-time fMRI",
        "N neural modulation",
        "N autism spectrum disorder (ASD)",
        "#text",
        "N fusiform face area (FFA)"
      ],
      "number_of_pages": null,
      "pages": "446",
      "publication": {
        "category": "Journal",
        "cite_score": 4.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1662-5161",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.787,
        "snip": 1.033,
        "subject_areas": [
          "Psychiatry and Mental Health",
          "Neurology",
          "Biological Psychiatry",
          "Neuropsychology and Physiological Psychology",
          "Behavioral Neuroscience"
        ],
        "title": "Frontiers in human neuroscience"
      },
      "publication_date": "2019-12-20",
      "selected": false,
      "title": "Self-Regulation of the Fusiform Face Area in Autism Spectrum: A Feasibility Study With Real-Time fMRI Neurofeedback.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85077369477&origin=inward"
      ]
    },
    {
      "abstract": "One cause of the persistence of income inequality may be rooted in people's resistance to change the existing income distribution. Prior studies have shown that the medial prefrontal cortex (mPFC) may be associated with the decision making that influences income distribution. However, it is unclear whether the mPFC is involved in income redistribution tasks when third-party decision makers are unaffected by the outcome of the decision. In this study, we elucidate the neural mechanism underlying the tolerance of income inequality and the decision making that is related to income redistribution. By applying the transcranial direct current stimulation (tDCS) over the mPFC, we investigate whether the change in the activation of the mPFC can influence a subject's inclination to expropriate a rich person's endowment and transfer it to a poor person. The main finding is that the anodal stimulation significantly reduced the subject's inclination to redistribute wealth from the rich to the poor, and lowered the rate of accepting options for redistribution. However, the willingness of income redistribution did not change following the cathodal stimulation compared with the sham condition. The effect of the anodal stimulation was constant across three types of initial inequality. The stimulation effect is likely caused by the subject's enhanced loss aversion or desire to reinforce social hierarchies.",
      "authors": [
        "Wang, Minda",
        "Li, Jianbiao",
        "Li, Dahui",
        "Zhu, Chengkang",
        "Wang, Yuanyuan"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.neulet.2019.134701",
      "keywords": [
        "D016428 Journal Article",
        "N tDCS",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Loss aversion",
        "N Social hierarchy",
        "N Redistribution",
        "N mPFC"
      ],
      "number_of_pages": null,
      "pages": "134701",
      "publication": {
        "category": "Journal",
        "cite_score": 5.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1872-7972",
        "publisher": "Elsevier Ireland Ltd",
        "sjr": 0.802,
        "snip": 0.777,
        "subject_areas": [
          "Neuroscience (all)"
        ],
        "title": "Neuroscience letters"
      },
      "publication_date": "2019-12-17",
      "selected": false,
      "title": "Modulation of income redistribution decisions by anodal tDCS over the medial prefrontal cortex.",
      "urls": []
    },
    {
      "abstract": "BACKGROUNDS Social hierarchy is one of the most influential social structures employed by social species. While dominants in such hierarchies can preferentially access rich resources, subordinates are forced into lower social statuses and lifestyles with inferior resources. Previous studies have indicated that the social rank regulates social behaviors and emotion in a variety of species, whereby individual organisms live within the framework of their ranks. However, in human societies, people, particularly young men, who cannot accept their own social status may show social withdrawal behaviors such as hikikomori to avoid confronting their circumstances.\nMETHODS This article reviews the neural mechanisms underlying social status identified in animal studies with rodents and primates, and assesses how social rank affects animal's social behaviors and emotion which may be relevant to modern type depression.\nRESULTS Several brain regions such as medial prefrontal cortex are implicated in the formation of animal's social status, which leads to the differences in vulnerability and resilience to social stress.\nCONCLUSION On the basis of these findings, we propose that physical interventions such as voluntary exercise, diet, transcranial direct current stimulation, and psychotherapy, rather than psychotropic drugs, may be useful therapeutic approaches for modern type depression, which is a typical example of social status conflict and a phenotype of adjustment disorder to the traditional hierarchical social order.",
      "authors": [
        "Komori, Takashi",
        "Makinodan, Manabu",
        "Kishimoto, Toshifumi"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1002/brb3.1464",
      "keywords": [
        "N modern-type depression",
        "D016428 Journal Article",
        "N motivation",
        "D016454 Review",
        "D013485 Research Support, Non-U.S. Gov't",
        "N hikikomori",
        "N social status",
        "N social dominance"
      ],
      "number_of_pages": null,
      "pages": "e01464",
      "publication": {
        "category": "Journal",
        "cite_score": 5.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2162-3279",
        "publisher": "John Wiley & Sons Inc.",
        "sjr": 0.834,
        "snip": 0.984,
        "subject_areas": [
          "Behavioral Neuroscience"
        ],
        "title": "Brain and behavior"
      },
      "publication_date": "2019-11-19",
      "selected": false,
      "title": "Social status and modern-type depression: A review.",
      "urls": []
    },
    {
      "abstract": "18 Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that applies a weak electric current to the scalp to modulate neuronal membrane potentials. Compared to other brain stimulation methods, tDCS is relatively safe, simple, and inexpensive to administer. Since excessive online gaming can negatively affect mental health and daily functioning, developing treatment options for gamers is necessary. Although tDCS over the dorsolateral prefrontal cortex (DLPFC) has demonstrated promising results for various addictions, it has not been tested in gamers. This paper describes a protocol and a feasibility study for applying repeated tDCS over the DLPFC and neuroimaging to examine the underlying neural correlates in gamers. At baseline, individuals who play online games report average weekly hours spent on games, complete questionnaires on addiction symptoms and self-control, and undergo brain F-\ufb02uoro-2-deoxyglucose positron emission tomography (FDG-PET). The tDCS protocol consists of 12 sessions over the DLPFC for 4 weeks (anode F3/cathode F4, 2 mA for 30 min per session). Then, a follow-up is conducted using the same protocol as the baseline. Individuals who do not play online games receive only baseline FDG-PET scans without tDCS. Changes of clinical characteristics and asymmetry of regional cerebral metabolic rate of glucose (rCMRglu) in the DLPFC are examined in gamers. In addition, asymmetry of rCMRglu is compared between gamers and non-gamers at baseline. In our experiment, 15 gamers received tDCS sessions and completed baseline and follow-up scans. Ten non-gamers underwent FDG-PET scans at the baseline. The tDCS reduced addiction symptoms, time spent on games, and increased self-control. Moreover, abnormal asymmetry of rCMRglu in the DLPFC at baseline was alleviated after tDCS. The current protocol may be useful for assessing treatment efficacy of tDCS and its underlying brain changes in gamers. Further randomized sham-controlled studies are warranted. Moreover, the protocol can be applied to other neurological and psychiatric disorders.",
      "authors": [
        "Lee, Sang Hoon",
        "Im, Jooyeon Jamie",
        "Oh, Jin Kyoung",
        "Choi, Eun Kyoung",
        "Yoon, Sujung",
        "Bikson, Marom",
        "Song, In-Uk",
        "Jeong, Hyeonseok",
        "Chung, Yong-An"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3791/60007",
      "keywords": [],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 2.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1940-087X",
        "publisher": "MYJoVE Corporation",
        "sjr": 0.454,
        "snip": 0.398,
        "subject_areas": [
          "Neuroscience (all)",
          "Chemical Engineering (all)",
          "Biochemistry, Genetics and Molecular Biology (all)",
          "Immunology and Microbiology (all)"
        ],
        "title": "Journal of visualized experiments : JoVE"
      },
      "publication_date": "2019-11-09",
      "selected": false,
      "title": "Transcranial Direct Current Stimulation for Online Gamers.",
      "urls": []
    },
    {
      "abstract": "INTRODUCTION: \u00e2\u0080\u009cBehavioural and psychological symptoms of dementia\u00e2\u0080\u009d (BPSD) refers to a heterogeneous group of clinical manifestations related to dementia, including apathy, depression, anxiety, delusions, hallucinations, sexual or social disinhibition, sleep-wake cycle disturbances, aggression, agitation and other behaviours considered inappropriate. Because of the complexity and heterogeneity of BPSD, as well as the fragility and multimorbidity of the elderly, pharmacological treatment appears to be limited in terms of safety and efficacy, and nonpharmacological therapies are today considered the first choice. There is growing evidence that interventional approaches such as electroconvulsive therapy (ECT), repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS), deep brain stimulation (DBS), and vagus nerve stimulation (VNS) could be safe and efficient options for several psychiatric illnesses in a population presenting resistance to and/or intolerance of pharmacotherapy. AIMS: The aim of the present work is to provide a qualitative review of the state of the art in interventional psychiatry in the treatment of BPSD. A particular focus will be on depression and agitation, which represent major stressors on caregivers and a primary cause of institutionalisation. CONCLUSIONS: ECT is probably the most promising interventional procedure needing further investigation in order to obtain specific protocols and a consensus on indications. Preliminary data on rTMS, tDCS, and VNS are encouraging although randomised controlled trials to investigate and compare their efficacy in the treatment of BPSD are still lacking. Their feasibility profile could represent an important advantage over ECT. DBS could represent a very effective therapy for behavioural disorders, but knowledge of the precise neuroanatomical targets for BPSD is currently too limited to justify this invasive approach. \u00c2\u00a9 2019 EMH Swiss Medical Publishers Ltd.. All rights reserved.",
      "authors": [
        "Swierkosz-Lenart, Kevin",
        "Mall, Jean-Fr\u00e9d\u00e9ric",
        "von Gunten, Armin"
      ],
      "categories": null,
      "citations": 3,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.4414/smw.2019.20140",
      "keywords": [
        "DBS",
        "ECT",
        "BPSD",
        "RTMS",
        "Dementia",
        "Interventional psychiatry",
        "VNS",
        "TDCS"
      ],
      "number_of_pages": null,
      "pages": "w20140",
      "publication": {
        "category": "Journal",
        "cite_score": 4.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1424-3997",
        "publisher": "SMW supporting association",
        "sjr": 0.575,
        "snip": 0.527,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "Swiss medical weekly"
      },
      "publication_date": "2019-10-27",
      "selected": false,
      "title": "Interventional psychiatry in the management of behavioural and psychological symptoms of dementia: a qualitative review.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85074161629&origin=inward"
      ]
    },
    {
      "abstract": "The ventromedial prefrontal cortex (vmPFC) is involved in regulation of negative emotion and decision-making, emotional and behavioral control, and active resilient coping. This pilot study examined the feasibility of training healthy subjects (n =\u200927) to self-regulate the vmPFC activity using a real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf). Participants in the experimental group (EG, n =\u200918) were provided with an ongoing vmPFC hemodynamic activity (rtfMRI-nf signal represented as variable-height bar). Individuals were instructed to raise the bar by self-relevant value-based thinking. Participants in the control group (CG, n =\u20099) performed the same task; however, they were provided with computer-generated sham neurofeedback signal. Results demonstrate that (a) both the CG and the EG show a higher vmPFC fMRI signal at the baseline than during neurofeedback training; (b) no significant positive training effect was seen in the vmPFC across neurofeedback runs; however, the medial prefrontal cortex, middle temporal gyri, inferior frontal gyri, and precuneus showed significant decreasing trends across the training runs only for the EG; (c) the vmPFC rtfMRI-nf signal associated with the fMRI signal across the default mode network (DMN). These findings suggest that it may be difficult to modulate a single DMN region without affecting other DMN regions. Observed decreased vmPFC activity during the neurofeedback task could be due to interference from the fMRI signal within other DMN network regions, as well as interaction with task-positive networks. Even though participants in the EG did not show significant positive increase in the vmPFC activity among neurofeedback runs, they were able to learn to accommodate the demand of self-regulation task to maintain the vmPFC activity with the help of a neurofeedback signal.",
      "authors": [
        "Mayeli, Ahmad",
        "Misaki, Masaya",
        "Zotev, Vadim",
        "Tsuchiyagaito, Aki",
        "Al Zoubi, Obada",
        "Phillips, Raquel",
        "Smith, Jared",
        "Stewart, Jennifer L",
        "Refai, Hazem",
        "Paulus, Martin P",
        "Bodurka, Jerzy"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1002/hbm.24805",
      "keywords": [
        "N functional connectivity",
        "D016428 Journal Article",
        "N vmPFC",
        "D052061 Research Support, N.I.H., Extramural",
        "N self-regulation",
        "D013485 Research Support, Non-U.S. Gov't",
        "N fMRI Neurofeedback",
        "N emotion",
        "N brain",
        "N default mode network"
      ],
      "number_of_pages": 11,
      "pages": "342-352",
      "publication": {
        "category": "Journal",
        "cite_score": 9.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1097-0193",
        "publisher": "Wiley-Liss Inc.",
        "sjr": 1.688,
        "snip": 1.395,
        "subject_areas": [
          "Radiological and Ultrasound Technology",
          "Anatomy",
          "Neurology",
          "Radiology, Nuclear Medicine and Imaging",
          "Neurology (clinical)"
        ],
        "title": "Human brain mapping"
      },
      "publication_date": "2019-10-21",
      "selected": false,
      "title": "Self-regulation of ventromedial prefrontal cortex activation using real-time fMRI neurofeedback-Influence of default mode network.",
      "urls": []
    },
    {
      "abstract": "Children with Attention Deficit (Hyperactivity) Disorder or AD(H)D can require treatment for which they need to experience long-lasting neurofeedback sessions. Children might not adhere to at-home treatment activities because of the nature of these sessions; thus, not getting the benefits of the program. To increase adherence and effectiveness of the treatment itself, we propose neurofeedback gaming and social encouragement. Our hypothesis is that by playing a collaborative neurofeedback game, children will be more adherent to their treatment and therefore derive a stronger benefit. For this purpose we designed the game \u00e2\u0080\u009cOrbit\u00e2\u0080\u009d, a first multiplayer prototype that was evaluated in a pilot study with five neuropsychologists. It was found that collaborative multiplayer games are suitable from a therapeutic standpoint and long-term use because of its higher social motivation and collaboration between children with AD(H)D; albeit there are some drawbacks including unreliability of electroencephalography (EEG) input and the risk for the collaborative environment to be distracting for the player. Copyright is held by the author/owner(s).",
      "authors": [
        "Arrambide, Karina",
        "Freiman Cormier, Lisa",
        "Wehbe, Rina R.",
        "Nacke, Lennart E.",
        "Gabele, Mareike",
        "Wagner, Sebastian",
        "Hansen, Christian"
      ],
      "categories": null,
      "citations": 4,
      "comments": null,
      "databases": [
        "Scopus",
        "ACM"
      ],
      "doi": "10.1145/3341215.3356301",
      "keywords": [
        "video games",
        "bci",
        "cognitive therapy",
        "games",
        "collaboration",
        "ad(h)d",
        "children",
        "game elements"
      ],
      "number_of_pages": 8,
      "pages": "341-348",
      "publication": {
        "category": "Conference Proceedings",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": "9781450368711",
        "issn": null,
        "publisher": "Association for Computing Machinery",
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Extended Abstracts of the Annual Symposium on Computer-Human Interaction in Play Companion Extended Abstracts"
      },
      "publication_date": "2019-10-17",
      "selected": false,
      "title": "The Development of \"Orbit\": The Collaborative BCI Game for Children with AD(H)D",
      "urls": [
        "https://dl.acm.org/doi/10.1145/3341215.3356301",
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85074859313&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND Approximately 20% of traumatic cervical spinal cord injuries result in tetraplegia. Neuroprosthetics are being developed to manage this condition and thus improve the lives of patients. We aimed to test the feasibility of a semi-invasive technique that uses brain signals to drive an exoskeleton.\nMETHODS We recruited two participants at Clinatec research centre, associated with Grenoble University Hospital, Grenoble, France, into our ongoing clinical trial. Inclusion criteria were age 18-45 years, stability of neurological deficits, a need for additional mobility expressed by the patient, ambulatory or hospitalised monitoring, registration in the French social security system, and signed informed consent. The exclusion criteria were previous brain surgery, anticoagulant treatments, neuropsychological sequelae, depression, substance dependence or misuse, and contraindications to magnetoencephalography (MEG), EEG, or MRI. One participant was excluded because of a technical problem with the implants. The remaining participant was a 28-year-old man, who had tetraplegia following a C4-C5 spinal cord injury. Two bilateral wireless epidural recorders, each with 64 electrodes, were implanted over the upper limb sensorimotor areas of the brain. Epidural electrocorticographic (ECoG) signals were processed online by an adaptive decoding algorithm to send commands to effectors (virtual avatar or exoskeleton). Throughout the 24 months of the study, the patient did various mental tasks to progressively increase the number of degrees of freedom.\nFINDINGS Between June 12, 2017, and July 21, 2019, the patient cortically controlled a programme that simulated walking and made bimanual, multi-joint, upper-limb movements with eight degrees of freedom during various reach-and-touch tasks and wrist rotations, using a virtual avatar at home (64\u00b70% [SD 5\u00b71] success) or an exoskeleton in the laboratory (70\u00b79% [11\u00b76] success). Compared with microelectrodes, epidural ECoG is semi-invasive and has similar efficiency. The decoding models were reusable for up to approximately 7 weeks without recalibration.\nINTERPRETATION These results showed long-term (24-month) activation of a four-limb neuroprosthetic exoskeleton by a complete brain-machine interface system using continuous, online epidural ECoG to decode brain activity in a tetraplegic patient. Up to eight degrees of freedom could be simultaneously controlled using a unique model, which was reusable without recalibration for up to about 7 weeks.\nFUNDING French Atomic Energy Commission, French Ministry of Health, Edmond J Safra Philanthropic Foundation, Fondation Motrice, Fondation Nanosciences, Institut Carnot, Fonds de Dotation Clinatec.",
      "authors": [
        "Benabid, Alim Louis",
        "Costecalde, Thomas",
        "Eliseyev, Andrey",
        "Charvet, Guillaume",
        "Verney, Alexandre",
        "Karakas, Serpil",
        "Foerster, Michael",
        "Lambert, Aur\u00e9lien",
        "Morini\u00e8re, Boris",
        "Abroug, Neil",
        "Schaeffer, Marie-Caroline",
        "Moly, Alexandre",
        "Sauter-Starace, Fabien",
        "Ratel, David",
        "Moro, Cecile",
        "Torres-Martinez, Napoleon",
        "Langar, Lilia",
        "Oddoux, Manuela",
        "Polosan, Mircea",
        "Pezzani, Stephane",
        "Auboiroux, Vincent",
        "Aksenova, Tetiana",
        "Mestais, Corinne",
        "Chabardes, Stephan"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/S1474-4422(19)30321-7",
      "keywords": [],
      "number_of_pages": 11,
      "pages": "1112-1122",
      "publication": {
        "category": "Journal",
        "cite_score": 62.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1474-4465",
        "publisher": "Elsevier Ltd.",
        "sjr": 9.819,
        "snip": 13.538,
        "subject_areas": [
          "Neurology (clinical)"
        ],
        "title": "The Lancet. Neurology"
      },
      "publication_date": "2019-10-03",
      "selected": false,
      "title": "An exoskeleton controlled by an epidural wireless brain-machine interface in a tetraplegic patient: a proof-of-concept demonstration.",
      "urls": []
    },
    {
      "abstract": "Transcranial electric stimulation (TES) can modulate intrinsic neural activity in the brain by injecting weak currents through electrodes attached to the scalp. TES has been widely used as a neuroscience tool to investigate how behavioural and physiological variables of brain function are modulated by electric stimulation of specific brain regions. For an unambiguous interpretation of TES experiments, it is important that the electric fields can be steered towards one or several brain regions-of-interest. However, the conductive proprieties of the human head impose inherent physical limitations on how focal the electric fields in the brain produced by multi-electrode TES can be. As a rule of thumb, it is not feasible to selectively target deep brain areas with TES, although focusing the field in some specific deeper locations might be possible due to favourable conductive properties in the surrounding tissue. In the present study, we first propose a computationally efficient method for the automatic determination of electrode placements and stimulation intensities to optimally affect a given target position. We provide a robust implementation of the optimization procedure that is able to adhere to safety constraints, while explicitly controlling both the number of active electrodes and the angular deviation of the field in the target area relative to the desired field direction. Leveraging the high computational efficiency of our method, we systematically assess the achievable focality of multi-electrode TES for all cortex positions, thereby investigating the dependence on the chosen constraints. Our results provide comprehensive insight into the limitations regarding the achievable TES dose and focality that are imposed by the biophysical constraints and the safety considerations of TES.",
      "authors": [
        "Saturnino, Guilherme Bicalho",
        "Siebner, Hartwig Roman",
        "Thielscher, Axel",
        "Madsen, Kristoffer Hougaard"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.neuroimage.2019.116183",
      "keywords": [
        "N Transcranial electric stimulation",
        "D016428 Journal Article",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Electric field simulations",
        "N Focality",
        "N Optimization",
        "N Mapping"
      ],
      "number_of_pages": null,
      "pages": "116183",
      "publication": {
        "category": "Journal",
        "cite_score": 11.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1095-9572",
        "publisher": "Academic Press Inc.",
        "sjr": 2.512,
        "snip": 1.782,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Neurology"
        ],
        "title": "NeuroImage"
      },
      "publication_date": "2019-09-13",
      "selected": false,
      "title": "Accessibility of cortical regions to focal TES: Dependence on spatial position, safety, and practical constraints.",
      "urls": []
    },
    {
      "abstract": "Endowment effect - the observation that people appear to attach more value to possessions than non-possessions - has been replicated in numerous experimental studies. Previous neuroimaging studies revealed that the medial prefrontal cortex (MPFC) plays a role in the endowment effect. To assess the possibility of a direct causal relationship between the activity of MPFC and the endowment effect, we used transcranial direct current stimulation (tDCS) to transiently alter the neural activity in MPFC. Subsequently, in three stimulation treatments, we assessed the presence of the endowment effect, which was demonstrated by a disparity between willingness to accept (WTA) and willingness to pay (WTP). The results indicated that the participants demonstrated the endowment effect for a mug in the anodal and sham treatments, whereas no endowment effect was observed in the cathodal treatment. Similarly, endowment effect was observed for the other item (notebook) in the anodal treatment, whereas no endowment effect was observed in the sham and cathodal treatments. In addition, the participants tended to sell higher and buy lower after receiving anodal tDCS over MPFC and buy higher after receiving cathodal tDCS over MPFC. As a result, the present study demonstrated a direct causal relationship between the activity of MPFC and the endowment effect.",
      "authors": [
        "Guo, Wenmin",
        "Shi, Jinchuan",
        "Lu, Xinbo",
        "Ye, Hang",
        "Luo, Jun"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3389/fnbeh.2019.00211",
      "keywords": [
        "N objective value",
        "N the medial prefrontal cortex",
        "N subjective value",
        "#text",
        "N endowment effect",
        "N transcranial direct current stimulation",
        "@UI"
      ],
      "number_of_pages": null,
      "pages": "211",
      "publication": {
        "category": "Journal",
        "cite_score": 4.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1662-5153",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.975,
        "snip": 0.965,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Behavioral Neuroscience",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Frontiers in behavioral neuroscience"
      },
      "publication_date": "2019-09-12",
      "selected": false,
      "title": "Modulating the Activity of MPFC With tDCS Alters Endowment Effect.",
      "urls": []
    },
    {
      "abstract": "Previous research has shown a link between eye contact and interpersonal motor resonance, indicating that the mirroring of observed movements is enhanced when accompanied with mutual eye contact between actor and observer. Here, we further explored the role of eye contact within a naturalistic two-person action context. Twenty-two participants observed simple hand movements combined with direct or averted gaze presented via a live model in a two-person setting or via video recordings, while transcranial magnetic stimulation was applied over the primary motor cortex (M1) to measure changes in M1 excitability. Skin conductance responses and gaze behavior were also measured to investigate the role of arousal and visual attention herein. Eye contact significantly enhanced excitability of the observer's M1 during movement observation within a two-person setting. Notably, participants with higher social responsiveness (Social Communication subscale of the Social Responsiveness Scale) displayed a more pronounced modulation of M1 excitability by eye gaze. Gaze-related modulations in M1 excitability were, however, not associated with differences in visual attention or autonomic arousal. In summary, the current study highlights the effectiveness and feasibility of adopting paradigms with high ecological validity for studying the modulation of mirror system processes by subtle social cues, such as eye gaze. \u00c2\u00a9 2019 The Author(s). Published by Oxford University Press.",
      "authors": [
        "Prinsen, Jellina",
        "Alaerts, Kaat"
      ],
      "categories": null,
      "citations": 22,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1093/scan/nsz064",
      "keywords": [
        "N transcranial magnetic stimulation (TMS)",
        "D016428 Journal Article",
        "N eye contact",
        "D013485 Research Support, Non-U.S. Gov't",
        "N skin conductance",
        "N action observation",
        "N mirror neuron system"
      ],
      "number_of_pages": 10,
      "pages": "967-976",
      "publication": {
        "category": "Journal",
        "cite_score": 6.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1749-5024",
        "publisher": "Oxford University Press",
        "sjr": 1.602,
        "snip": 1.285,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Experimental and Cognitive Psychology"
        ],
        "title": "Social cognitive and affective neuroscience"
      },
      "publication_date": "2019-09-01",
      "selected": false,
      "title": "Eye contact enhances interpersonal motor resonance: comparing video stimuli to a live two-person action context.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85076871629&origin=inward"
      ]
    },
    {
      "abstract": "Many supporters of 'moral bioenhancement' (MBE), the use of biomedical interventions for moral improvement, have been criticised for having unrealistic proposals. The interventions they suggest have often been called infeasible and their implementation plans vague or unethical. I dispute these criticisms by showing that various interventions to implement MBE are practically and ethically feasible enough to warrant serious consideration. Such interventions include transcranial direct current stimulation over the medial and dorsolateral prefrontal cortex, as well as supplementation with lithium and omega-3. Considering their efficacy and feasibility, it is strange that these interventions have rarely been proposed or discussed as MBE. I review evidence that each of those interventions can reduce antisocial behaviour, reduce racial bias, increase executive function or increase prosocial traits like fairness and altruism. I then specify and defend realistic, ethically permissible ways to implement these interventions, especially for violent offenders and public servants-the former as rehabilitation and the latter to meet the high standards of their occupations. These interventions could be given to violent offenders in exchange for a reduced sentence or compulsorily in some cases. Potential intervention methods for non-prisoners include increasing the USDA-recommended dose of omega-3, encouraging food companies to supplement their products with omega-3 or trace lithium, requiring MBE for employment as a police officer or political leader, and insurance companies providing discounts for undergoing MBE. In some reasonably limited form, using these interventions may be a good first step to implement the project of MBE.",
      "authors": [
        "Conan, Gregory Mark"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1136/medethics-2019-105534",
      "keywords": [
        "N non-invasive brain stimulation",
        "D016428 Journal Article",
        "D013485 Research Support, Non-U.S. Gov't",
        "N prisoners",
        "N behavior modification",
        "N neuroethics",
        "N enhancement"
      ],
      "number_of_pages": 5,
      "pages": "43-47",
      "publication": {
        "category": "Journal",
        "cite_score": 6.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1473-4257",
        "publisher": "BMJ Publishing Group",
        "sjr": 1.111,
        "snip": 1.425,
        "subject_areas": [
          "Arts and Humanities (miscellaneous)",
          "Issues, Ethics and Legal Aspects",
          "Health Policy",
          "Health (social science)"
        ],
        "title": "Journal of medical ethics"
      },
      "publication_date": "2019-08-28",
      "selected": false,
      "title": "Frequently overlooked realistic moral bioenhancement interventions.",
      "urls": []
    },
    {
      "abstract": "Real-time functional magnetic resonance imaging neurofeedback (rtfMRI-NF) is a prospective tool to enhance the emotion regulation capability of participants and to alleviate their emotional disorders. The hippocampus is a key brain region in the emotional brain network and plays a significant role in social cognition and emotion processing in the brain. However, few studies have focused on the emotion NF of the hippocampus. This study investigated the feasibility of NF training of healthy participants to self-regulate the activation of the hippocampus and assessed the effect of rtfMRI-NF on the hippocampus before and after training. Twenty-six right-handed healthy volunteers were randomly assigned to the experimental group receiving hippocampal rtfMRI-NF (n = 13) and the control group (CG) receiving rtfMRI-NF from the intraparietal sulcus rtfMRI-NF (n = 13) and completed a total of four NF runs. The hippocampus and the intraparietal sulcus were defined based on the Montreal Neurological Institute (MNI) standard template, and NF signal was measured as a percent signal change relative to the baseline obtained by averaging the fMRI signal for the preceding 20 s long rest block. NF signal (percent signal change) was updated every 2 s and was displayed on the screen. The amplitude of low-frequency fluctuation and regional homogeneity values was calculated to evaluate the effects of NF on spontaneous neural activity in resting-state fMRI. A standard general linear model (GLM) analysis was separately conducted for each fMRI NF run. Results showed that the activation of hippocampus increased after four NF training runs. The hippocampal activity of the experiment group participants was higher than that of the CG. They also showed elevated hippocampal activity and the greater amygdala\u00e2\u0080\u0093hippocampus connectivity. The anterior temporal lobe, parahippocampal gyrus, hippocampus, and amygdala of brain regions associated with emotional processing were activated during training. We presented a proof-of-concept study using rtfMRI-NF for hippocampus up-regulation in the recall of positive autobiographical memories. The current study may provide a new method to regulate our emotions and can potentially be applied to the clinical treatment of emotional disorders. \u00c2\u00a9 2019 Zhu, Gao, Tong, Li, Wang, Zhang, Yang and Yan.",
      "authors": [
        "Zhu, Yashuo",
        "Gao, Hui",
        "Tong, Li",
        "Li, ZhongLin",
        "Wang, Linyuan",
        "Zhang, Chi",
        "Yang, Qiang",
        "Yan, Bin"
      ],
      "categories": null,
      "citations": 56,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.3389/fnhum.2019.00242",
      "keywords": [
        "@UI",
        "N emotion",
        "N autobiographical memories",
        "N real-time fMRI neurofeedback",
        "N regulation",
        "N hippocampus",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "242",
      "publication": {
        "category": "Journal",
        "cite_score": 4.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1662-5161",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.787,
        "snip": 1.033,
        "subject_areas": [
          "Psychiatry and Mental Health",
          "Neurology",
          "Biological Psychiatry",
          "Neuropsychology and Physiological Psychology",
          "Behavioral Neuroscience"
        ],
        "title": "Frontiers in human neuroscience"
      },
      "publication_date": "2019-07-16",
      "selected": false,
      "title": "Emotion Regulation of Hippocampus Using Real-Time fMRI Neurofeedback in Healthy Human.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85069542064&origin=inward"
      ]
    },
    {
      "abstract": "Objective: Posttraumatic stress disorder (PTSD) is a highly prevalent psychiatric disorder associated with disruption in social and occupational function. Transcranial magnetic stimulation (TMS) represents a novel approach to PTSD, and intermittent theta-burst stimulation (iTBS) is a new, more rapid administration protocol with data supporting efficacy in depression. The authors conducted a sham-controlled study of iTBS for PTSD. Methods: Fifty veterans with PTSD received 10 days of sham-controlled iTBS (1,800 pulses/day), followed by 10 unblinded sessions. Primary outcome measures included acceptability (retention rates), changes in PTSD symptoms (clinician- and self-rated), quality of life, social and occupational function, and depression, obtained at the end of 2 weeks; analysis of variance was used to compare active with sham stimulation. Secondary outcomes were evaluated 1 month after treatment, using mixed-model analyses. Resting-state functional MRI was acquired at pretreatment baseline on an eligible subset of participants (N=26) to identify response predictors. Results: Retention was high, side effects were consistent with standard TMS, and blinding was successful. At 2 weeks, active iTBS was significantly associated with improved social and occupational function (Cohen's d=0.39); depression was improved with iTBS compared with the sham treatment (d=20.45), but the difference fell short of significance, and moderate nonsignificant effect sizes were observed on self-reported PTSD symptoms (d=20.34). One-month outcomes, which incorporated data from the unblinded phase of the study, indicated superiority of active iTBS on clinician- and self-rated PTSD symptoms (d=20.74 and 20.63, respectively), depression (d=20.47), and social and occupational function (d=0.93) (all significant). Neuroimaging indicated that clinical improvement was significantly predicted by stronger (greater positive) connectivity within the default mode network and by anticorrelated (greater negative) cross-network connectivity. Conclusions: iTBS appears to be a promising new treatment for PTSD. Most clinical improvements from stimulation occurred early, which suggests a need for further investigation of optimal iTBS time course and duration. Consistent with previous neuroimaging studies of TMS, default mode network connectivity played an important role in response prediction. \u00c2\u00a9 2019 American Psychiatric Association. All rights reserved.",
      "authors": [
        "Philip, Noah S",
        "Barredo, Jennifer",
        "Aiken, Emily",
        "Larson, Victoria",
        "Jones, Richard N",
        "Shea, M Tracie",
        "Greenberg, Benjamin D",
        "van 't Wout-Frank, Mascha"
      ],
      "categories": null,
      "citations": 97,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1176/appi.ajp.2019.18101160",
      "keywords": [
        "N Brain Imaging Techniques",
        "D016428 Journal Article",
        "D013485 Research Support, Non-U.S. Gov't",
        "D016449 Randomized Controlled Trial",
        "D013486 Research Support, U.S. Gov't, Non-P.H.S.",
        "N Theta Burst Stimulation",
        "N Posttraumatic Stress Disorder",
        "N Transcranial Magnetic Stimulation"
      ],
      "number_of_pages": 10,
      "pages": "939-948",
      "publication": {
        "category": "Journal",
        "cite_score": 20.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1535-7228",
        "publisher": "American Psychiatric Association",
        "sjr": 4.231,
        "snip": 3.582,
        "subject_areas": [
          "Psychiatry and Mental Health"
        ],
        "title": "The American journal of psychiatry"
      },
      "publication_date": "2019-06-24",
      "selected": false,
      "title": "Theta-Burst Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85070683876&origin=inward"
      ]
    },
    {
      "abstract": "Background: Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique, which has yielded promising results in treating major depressive disorder. However, its effect on treatment-resistant depression remains to be determined. Meanwhile, as an emerging treatment option, patients' acceptability of tDCS is worthy of attention. Methods: This pilot study enrolled 18 patients (women = 13) with treatment-resistant unipolar (n = 13) or bipolar (n = 5) depression. Twelve sessions of tDCS were administered with anode over F3 and cathode over F4. Each session delivered a current of 2 mA for 30 min per ten working days, and at the 4th and 6th week. Severity of depression was determined by Montgomery-\u00c3\u0085sberg Depression Rating Scale (MADRS); cognitive performance was assessed by a computerized battery. Results: Scores of MADRS at baseline (29.6, SD = 9.7) decreased significantly to 22.9 (11.7) (p = 0.03) at 6 weeks and 21.5 (10.3) (p = 0.01) at 8 weeks. Six (33.3%) participants were therapeutically responsive to tDCS. MADRS scores of responders were significantly lower than those of non-responders at the 6th and 8th week. Regarding change of cognitive performance, improved accuracy of paired association (p = 0.017) and social cognition (p = 0.047) was observed at the 8th week. Overall, tDCS was perceived as safe and tolerable. For the majority of patients, it is preferred than pharmacotherapy and psychotherapy. Conclusions: TDCS can be a desirable option for treatment-resistant depression, however, its efficacy may be delayed; identifying predictors of therapeutic response may achieve a more targeted application. Larger controlled studies with optimized montages and sufficient periods of observation are warranted. Trial registration: This trial has been registered at the Chinese Clinical Trial Registry (ChiCTR-INR-16008179). \u00c2\u00a9 2019 The Author(s).",
      "authors": [
        "Li, Min-Shan",
        "Du, Xiang-Dong",
        "Chu, Hsiao-Chi",
        "Liao, Yen-Ying",
        "Pan, Wen",
        "Li, Zhe",
        "Hung, Galen Chin-Lun"
      ],
      "categories": null,
      "citations": 22,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1186/s12888-019-2119-2",
      "keywords": [
        "D016430 Clinical Trial",
        "D016428 Journal Article",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Transcranial direct-current stimulation",
        "N Treatment-resistant depression",
        "N Cognitive ability"
      ],
      "number_of_pages": null,
      "pages": "180",
      "publication": {
        "category": "Journal",
        "cite_score": 5.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1471-244X",
        "publisher": "BioMed Central Ltd.",
        "sjr": 1.291,
        "snip": 1.535,
        "subject_areas": [
          "Psychiatry and Mental Health"
        ],
        "title": "BMC psychiatry"
      },
      "publication_date": "2019-06-11",
      "selected": false,
      "title": "Delayed effect of bifrontal transcranial direct current stimulation in patients with treatment-resistant depression: a pilot study.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85067111414&origin=inward"
      ]
    },
    {
      "abstract": "To foster performance across all levels of sports practice, physical training has been integrated with various mental training practices. Recently, an integrative approach to neurocognitive enhancement tried to combine the strengths of mental practices (i.e. mindfulness) and of training with neurofeedback devices. Based on previous validation studies showing the effect of a combined mindfulness-neurofeedback program on neurocognitive efficiency and stress/anxiety levels, we aimed at testing the feasibility and potential of that intensive combined program for improving psychological well-being and attention regulation in sport contexts. 50 participants (sportspeople and volunteers not regularly involved in sports) were divided into groups undergoing experimental and active control training programs. The experimental one was based on breathing-awareness practices supported by a wearable neurofeedback, while the active control one included only breathing practices. Before and after training participants underwent standardized neuropsychological and electrophysiological assessment. Data analysis highlighted a significant reduction of response times and false alarms at computerized cognitive tasks in sportspeople who completed the training, as well as a consistent improvement of the N2 event-related potential - a marker of attention regulation processes. We have also observed a general reduction of perceived stress and increased ability to keep a non-evaluative stance. Findings extend available observations on cognitive and neural effects of combined mindfulness-neurofeedback practice by showing that it is possible to observe training effects even after a limited period of practice among sportspeople. Such early training effects might mirror optimized implicit learning curves due to peculiar sensitivity to bodily signals and awareness.",
      "authors": [
        "Crivelli, Davide",
        "Fronda, Giulia",
        "Balconi, Michela"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.neuroscience.2019.05.066",
      "keywords": [
        "@UI",
        "N neuroenhancement",
        "N self-regulation",
        "N neurofeedback",
        "N sport",
        "N wearable devices",
        "#text",
        "N mindfulness"
      ],
      "number_of_pages": 11,
      "pages": "83-93",
      "publication": {
        "category": "Journal",
        "cite_score": 6.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1873-7544",
        "publisher": "Elsevier Ltd.",
        "sjr": 1.006,
        "snip": 0.846,
        "subject_areas": [
          "Neuroscience (all)"
        ],
        "title": "Neuroscience"
      },
      "publication_date": "2019-06-10",
      "selected": false,
      "title": "Neurocognitive Enhancement Effects of Combined Mindfulness-Neurofeedback Training in Sport.",
      "urls": []
    },
    {
      "abstract": "Preterm birth is associated with heightened risk for attention-deficit/hyperactivity disorder (ADHD)-like symptoms and neurocognitive impairments, including impairments in performance monitoring. Here, we investigate the cognitive and neurophysiological processes from a performance-monitoring task in preterm-born adolescents and examine whether these processes in preterm-born adolescents reflect identical neurophysiological impairments to those observed in term-born adolescents with ADHD. We compared 186 preterm-born individuals to 69 term-born individuals with ADHD and 135 term-born controls on cognitive-performance measures and event-related potentials (ERPs) of conflict monitoring (N2) and error processing (ERN, Pe) from a flanker task. Preterm-born adolescents demonstrated reduced N2, ERN and Pe amplitudes, compared to controls, and similar ERN and Pe impairments to term-born adolescents with ADHD. While ADHD symptoms correlated with ERN amplitude at FCz among the preterm-born, ERN amplitude at Fz, N2 and Pe amplitude were not associated with ADHD symptoms. Preterm-born individuals show impairments on neurophysiological indices of conflict monitoring (N2) and error processing (ERN and Pe). Early neurophysiological error processing may be a marker underlying the processes linked to the increased risk for ADHD among preterm-born individuals. Error detection processes are malleable and potential targets for non-pharmacological interventions. Preterm-born individuals are likely to benefit from early interventions.",
      "authors": [
        "Rommel, Anna-Sophie",
        "James, Sarah-Naomi",
        "McLoughlin, Gr\u00e1inne",
        "Michelini, Giorgia",
        "Banaschewski, Tobias",
        "Brandeis, Daniel",
        "Asherson, Philip",
        "Kuntsi, Jonna"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1371/journal.pone.0214864",
      "keywords": [],
      "number_of_pages": null,
      "pages": "e0214864",
      "publication": {
        "category": "Journal",
        "cite_score": 6.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1932-6203",
        "publisher": "Public Library of Science",
        "sjr": 0.885,
        "snip": 1.253,
        "subject_areas": [
          "Multidisciplinary"
        ],
        "title": "PloS one"
      },
      "publication_date": "2019-04-11",
      "selected": false,
      "title": "Impairments in error processing and their association with ADHD symptoms in individuals born preterm.",
      "urls": []
    },
    {
      "abstract": "OBJECTIVE To estimate the comparative clinical efficacy and acceptability of non-surgical brain stimulation for the acute treatment of major depressive episodes in adults.\nDESIGN Systematic review with pairwise and network meta-analysis.\nDATA SOURCES Electronic search of Embase, PubMed/Medline, and PsycINFO up to 8 May 2018, supplemented by manual searches of bibliographies of several reviews (published between 2009 and 2018) and included trials.\nELIGIBILITY CRITERIA FOR SELECTING STUDIES Clinical trials with random allocation to electroconvulsive therapy (ECT), transcranial magnetic stimulation (repetitive (rTMS), accelerated, priming, deep, and synchronised), theta burst stimulation, magnetic seizure therapy, transcranial direct current stimulation (tDCS), or sham therapy.\nMAIN OUTCOME MEASURES Primary outcomes were response (efficacy) and all cause discontinuation (discontinuation of treatment for any reason) (acceptability), presented as odds ratios with 95% confidence intervals. Remission and continuous depression severity scores after treatment were also examined.\nRESULTS 113 trials (262 treatment arms) that randomised 6750 patients (mean age 47.9 years; 59% women) with major depressive disorder or bipolar depression met the inclusion criteria. The most studied treatment comparisons were high frequency left rTMS and tDCS versus sham therapy, whereas recent treatments remain understudied. The quality of the evidence was typically of low or unclear risk of bias (94 out of 113 trials, 83%) and the precision of summary estimates for treatment effect varied considerably. In network meta-analysis, 10 out of 18 treatment strategies were associated with higher response compared with sham therapy: bitemporal ECT (summary odds ratio 8.91, 95% confidence interval 2.57 to 30.91), high dose right unilateral ECT (7.27, 1.90 to 27.78), priming transcranial magnetic stimulation (6.02, 2.21 to 16.38), magnetic seizure therapy (5.55, 1.06 to 28.99), bilateral rTMS (4.92, 2.93 to 8.25), bilateral theta burst stimulation (4.44, 1.47 to 13.41), low frequency right rTMS (3.65, 2.13 to 6.24), intermittent theta burst stimulation (3.20, 1.45 to 7.08), high frequency left rTMS (3.17, 2.29 to 4.37), and tDCS (2.65, 1.55 to 4.55). Network meta-analytic estimates of active interventions contrasted with another active treatment indicated that bitemporal ECT and high dose right unilateral ECT were associated with increased response. All treatment strategies were at least as acceptable as sham therapy.\nCONCLUSIONS These findings provide evidence for the consideration of non-surgical brain stimulation techniques as alternative or add-on treatments for adults with major depressive episodes. These findings also highlight important research priorities in the specialty of brain stimulation, such as the need for further well designed randomised controlled trials comparing novel treatments, and sham controlled trials investigating magnetic seizure therapy.",
      "authors": [
        "Mutz, Julian",
        "Vipulananthan, Vijeinika",
        "Carter, Ben",
        "Hurlemann, Ren\u00e9",
        "Fu, Cynthia H Y",
        "Young, Allan H"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1136/bmj.l1079",
      "keywords": [],
      "number_of_pages": null,
      "pages": "l1079",
      "publication": {
        "category": "Journal",
        "cite_score": 15.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1756-1833",
        "publisher": "BMJ Publishing Group",
        "sjr": 2.867,
        "snip": 8.667,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "BMJ (Clinical research ed.)"
      },
      "publication_date": "2019-03-27",
      "selected": false,
      "title": "Comparative efficacy and acceptability of non-surgical brain stimulation for the acute treatment of major depressive episodes in adults: systematic review and network meta-analysis.",
      "urls": []
    },
    {
      "abstract": "BACKGROUND Deficient emotion regulation and exaggerated anxiety represent a major transdiagnostic psychopathological marker. On the neural level these deficits have been closely linked to impaired, yet treatment-sensitive, prefrontal regulatory control over the amygdala. Gaining direct control over these pathways could therefore provide an innovative and promising intervention to regulate exaggerated anxiety. To this end the current proof-of-concept study evaluated the feasibility, functional relevance and maintenance of a novel connectivity-informed real-time fMRI neurofeedback training.\nMETHODS In a randomized crossover sham-controlled design, 26 healthy subjects with high anxiety underwent real-time fMRI-guided neurofeedback training to enhance connectivity between the ventrolateral prefrontal cortex (vlPFC) and the amygdala (target pathway) during threat exposure. Maintenance of regulatory control was assessed after 3 days and in the absence of feedback. Training-induced changes in functional connectivity of the target pathway and anxiety ratings served as primary outcomes.\nRESULTS Training of the target, yet not the sham control, pathway significantly increased amygdala-vlPFC connectivity and decreased levels of anxiety. Stronger connectivity increases were significantly associated with higher anxiety reduction on the group level. At the follow-up, volitional control over the target pathway was maintained in the absence of feedback.\nCONCLUSIONS The present results demonstrate for the first time that successful self-regulation of amygdala-prefrontal top-down regulatory circuits may represent a novel intervention to control anxiety. As such, the present findings underscore both the critical contribution of amygdala-prefrontal circuits to emotion regulation and the therapeutic potential of connectivity-informed real-time neurofeedback.",
      "authors": [
        "Zhao, Zhiying",
        "Yao, Shuxia",
        "Li, Keshuang",
        "Sindermann, Cornelia",
        "Zhou, Feng",
        "Zhao, Weihua",
        "Li, Jianfu",
        "L\u00fchrs, Michael",
        "Goebel, Rainer",
        "Kendrick, Keith M",
        "Becker, Benjamin"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1159/000496057",
      "keywords": [
        "D016428 Journal Article",
        "N Connectivity",
        "N Functional magnetic resonance imaging",
        "N Treatment",
        "D013485 Research Support, Non-U.S. Gov't",
        "D016449 Randomized Controlled Trial",
        "N Real-time neurofeedback",
        "N Network",
        "N Anxiolytic treatment",
        "N Prefrontal cortex",
        "N Anxiety",
        "N Amygdala",
        "N Emotion regulation"
      ],
      "number_of_pages": 11,
      "pages": "5-15",
      "publication": {
        "category": "Journal",
        "cite_score": 22.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1423-0348",
        "publisher": "S. Karger AG",
        "sjr": 4.738,
        "snip": 3.875,
        "subject_areas": [
          "Applied Psychology",
          "Psychiatry and Mental Health",
          "Clinical Psychology"
        ],
        "title": "Psychotherapy and psychosomatics"
      },
      "publication_date": "2019-01-30",
      "selected": false,
      "title": "Real-Time Functional Connectivity-Informed Neurofeedback of Amygdala-Frontal Pathways Reduces Anxiety.",
      "urls": []
    },
    {
      "abstract": "The social order of human societies is largely maintained by social norms. However, we still know little about the cognitive and emotional foundations that shape social norms, which makes it difficult, if not impossible, to understand how social norms are developed and maintained. Prior neural studies, which mainly perform second-party punishment based on the ultimatum framework, rarely explore the relevant brain areas as well as the neural mechanisms of third-party punishment driven by social norms. In the current study, we provide evidences that support the influences of two types of mechanisms (i.e., negative emotions and self-interest mechanisms) on social norms compliance of third parties at opposite directions. Meanwhile, right dorsolateral prefrontal area (DLPFC) is found to play a crucial role in this process. In this study, we used transcranial direct current stimulation (tDCS) to investigate whether increasing or decreasing right DLPFC excitability influenced third-party punishment in a dictator game. Following an experimental design of \u00e2\u0080\u009cbetween-subject (tDCS treatments: anodal, cathodal, sham) \u00c3\u0097 within-subject (cost of punishment treatments: without cost, with cost)\u00e2\u0080\u009d, ninety participants were first randomly assigned to receive anodal, cathodal, or sham stimulation in 15 minutes. They then performed two dictator game tasks as third parties. In Task I (without cost) participants did not need to carry any costs for their punishment (none-cost task), while in Task II (with cost) they were required to pay for their punishment actions. The results are given as follows. We first performed repeated measured ANOVA and one-way ANOVA to examine the effect of tDCS treatment (anodal, cathodal and sham) on emotion response. We found a significant main effect of tDCS on emotion response. Meanwhile, post-hoc analysis (SNK) showed that anodal stimulation decreased negative emotions while cathodal stimulation enhanced negative emotions. Second, the results of repeated measured ANOVA and one-way ANOVA showed a significant main effect of tDCS on punishment in the none-cost Task \u00e2\u0085 , and post-hoc analysis (SNK) showed that cathodal stimulation significantly increased punishment while the effect of anodal stimulation was insignificant. Third, we also conducted repeated measured ANOVA and one-way ANOVA to test whether the difference of the punishment between the two tasks was affected by tDCS treatments. We found that the main effect of tDCS was significant. Moreover, post-hoc analysis (SNK) showed that the difference of punishment between the two tasks was significantly higher for cathodal stimulation than for sham stimulation, while the difference of punishment between the two tasks for anodal stimulation was insignificant compared to that of sham stimulation. The present study provides one of the first neural evidences for the role of right DLPFC in third-parties\u00e2\u0080\u0099 social norms compliance. The results indicate that DLPFC, by affecting the processes of negative emotions and self-interest, is an important brain area of social norms compliance. When third parties face violations of social norms, their brains first release negative emotions that drive third parties to punish violators. Further, if third parties need to pay for their compliance with social norms, their rational goals about self-interest weaken negative emotional impulses. Finally, the compliance with social norms depends on the trade-offs between negative emotions and self-interest mechanisms. \u00c2\u00a9 2019, Science Press. All rights reserved.",
      "authors": [
        "Yin, X.",
        "Li, J.",
        "Chen, S.",
        "Liu, X.",
        "Hao, J."
      ],
      "categories": null,
      "citations": 1,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3724/SP.J.1041.2019.00571",
      "keywords": [
        "Emotion",
        "Dorsolateral prefrontal cortex (DLPFC)",
        "Third-party punishment",
        "Social norms",
        "Transcranial direct current stimulation (tDCS)"
      ],
      "number_of_pages": 13,
      "pages": "571-583",
      "publication": {
        "category": "Journal",
        "cite_score": 1.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "0439755X",
        "publisher": "Science Press",
        "sjr": 0.362,
        "snip": 0.578,
        "subject_areas": [
          "Psychology (all)"
        ],
        "title": "Acta Psychologica Sinica"
      },
      "publication_date": "2019-01-01",
      "selected": false,
      "title": "Neural mechanisms of third-party punishment: Evidence from transcranial direct current stimulation",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85075239352&origin=inward"
      ]
    },
    {
      "abstract": "Recent studies have demonstrated that the right dorsolateral prefrontal cortex and the right temporoparietal junction are causally involved in social norm compliance: its activation corresponds with the third-party norm enforcement behavior, known as third-party punishment. The current study aimed to address the inconsistencies in effects of brain stimulation methods on right dorsolateral prefrontal cortex and right temporoparietal junction to clarify its role on third-party punishment. Despite a decade of neuroimaging research, the interaction between the right temporoparietal junction and right dorsolateral prefrontal cortex in third-party punishment remained unclear. Here, we tested the hypothesis that a third party\u00e2\u0080\u0099s decision to punish norm violations depends on the activity of the entire right dorsolateral prefrontal cortex-right temporoparietal junction network. We used transcranial direct current stimulation to independently or jointly modulate right temporoparietal junction and right dorsolateral prefrontal cortex activity during the third-party dictator game. We found a significant effect of anodal transcranial direct current stimulation of the right temporoparietal junction, which decreased the third-party punishment of moderately unfair splits. Joint stimulation of the right temporoparietal junction (by anodal transcranial direct current stimulation) and right dorsolateral prefrontal cortex (by cathodal transcranial direct current stimulation) produced a marginal effect on third-party punishment. Our results suggested that the right temporoparietal junction could modulate the perceived moral costs of third-party punishment. \u00c2\u00a9 2019 National Research University Higher School of Economics. All rights reserved.",
      "authors": [
        "Zinchenko, O.O.",
        "Belianin, A.V.",
        "Klucharev, V.A."
      ],
      "categories": null,
      "citations": 2,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.17323/1813-8918-2019-3-529-550",
      "keywords": [
        "Third-party punishment",
        "Social norms",
        "Temporoparietal junction",
        "Dorsolateral prefrontal cortex",
        "Transcranial direct current stimulation"
      ],
      "number_of_pages": 22,
      "pages": "529-550",
      "publication": {
        "category": "Journal",
        "cite_score": 0.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "18138918",
        "publisher": "National Research University Higher School of Economics",
        "sjr": 0.208,
        "snip": 0.524,
        "subject_areas": [
          "Cultural Studies",
          "Education",
          "Psychology (all)"
        ],
        "title": "Psychology, Journal of the Higher School of Economics"
      },
      "publication_date": "2019-01-01",
      "selected": false,
      "title": "The role of the temporoparietal and prefrontal cortices in a third-party punishment: A tDCS study",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85083695892&origin=inward"
      ]
    },
    {
      "abstract": "Social norms are a common motivator or de-motivator of behavior through the need of humans to comply with acceptable behaviors of their social groups. Converging evidence from functional neuroimaging and noninvasive brain stimulation studies suggest that the right dorsolateral prefrontal cortex (rDLPFC) is involved in social norm compliance. Extending this view, we suggest that rDLPFC may not act uniformly when men and women face different types of fairness norm compliance situations, and that there may be a sequential update of norm compliance after experiencing punishment. Using High-Definition Transcranial Direct Current Stimulation (HD-tDCS) on 100 participants playing a sequence of economic game trials, the current study showed that (1) the right dorsolateral prefrontal cortex (rDLPFC) is involved in both voluntary and sanction-induced fairness norm compliance, (2) it has an opposite role in the two types of compliance, (3) there are sex-based differences in rDLPFC roles in fairness norm compliance, and (4) post-punishment fairness compliance is reduced compared to baseline. \u00c2\u00a9 2018 Elsevier B.V.",
      "authors": [
        "Chen, Wanting",
        "Zhang, Shuyue",
        "Turel, Ofir",
        "Peng, Youqing",
        "Chen, Hong",
        "He, Qinghua"
      ],
      "categories": null,
      "citations": 11,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1016/j.bbr.2018.12.040",
      "keywords": [
        "N Learning",
        "N Sequential updating",
        "N Gender differences",
        "D016428 Journal Article",
        "D013485 Research Support, Non-U.S. Gov't",
        "N rDLPFC",
        "N HD-tDCS",
        "N Fairness norm compliance"
      ],
      "number_of_pages": 9,
      "pages": "104-112",
      "publication": {
        "category": "Journal",
        "cite_score": 6.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1872-7549",
        "publisher": "Elsevier",
        "sjr": 0.881,
        "snip": 0.802,
        "subject_areas": [
          "Behavioral Neuroscience"
        ],
        "title": "Behavioural brain research"
      },
      "publication_date": "2018-12-21",
      "selected": false,
      "title": "Sex-based differences in right dorsolateral prefrontal cortex roles in fairness norm compliance.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85059213205&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND BACKGROUND We developed a brain-machine interface (BMI) system for poststroke patients with severe hemiplegia to detect event-related desynchronization (ERD) on scalp electroencephalogram (EEG) and to operate a motor-driven hand orthosis combined with neuromuscular electrical stimulation. ERD arises when the excitability of the ipsi-lesional sensorimotor cortex increases.\nOBJECTIVE OBJECTIVE The aim of this study was to evaluate our hypothesis that motor training using this BMI system could improve severe hemiparesis that is resistant to improvement by conventional rehabilitation. We, therefore, planned and implemented a randomized controlled clinical trial (RCT) to evaluate the effectiveness and safety of intensive rehabilitation using the BMI system.\nMETHODS METHODS We conducted a single blind, multicenter RCT and recruited chronic poststroke patients with severe hemiparesis more than 90 days after onset (N=40). Participants were randomly allocated to the BMI group (n=20) or the control group (n=20). Patients in the BMI group repeated 10-second motor attempts to operate EEG-BMI 40 min every day followed by 40 min of conventional occupational therapy. The interventions were repeated 10 times in 2 weeks. Control participants performed a simple motor imagery without servo-action of the orthosis, and electrostimulation was given for 10 seconds for 40 min, similar to the BMI intervention. Overall, 40 min of conventional occupational therapy was also given every day after the control intervention, which was also repeated 10 times in 2 weeks. Motor functions and electrophysiological phenotypes of the paretic hands were characterized before (baseline), immediately after (post), and 4 weeks after (follow-up) the intervention. Improvement in the upper extremity score of the Fugl-Meyer assessment between baseline and follow-up was the main outcome of this study.\nRESULTS RESULTS Recruitment started in March 2017 and ended in July 2018. This trial is currently in the data correcting phase. This RCT is expected to be completed by October 31, 2018.\nCONCLUSIONS CONCLUSIONS No widely accepted intervention has been established to improve finger function of chronic poststroke patients with severe hemiparesis. The results of this study will provide clinical data for regulatory approval and novel, important understanding of the role of sensory-motor feedback based on BMI to induce neural plasticity and motor recovery.\nTRIAL REGISTRATION BACKGROUND UMIN Clinical Trials Registry UMIN000026372; https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi? recptno=R000030299 (Archived by WebCite at http://www.webcitation.org/743zBJj3D).\nINTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID) UNASSIGNED DERR1-10.2196/12339.",
      "authors": [
        "Mizuno, Katsuhiro",
        "Abe, Takayuki",
        "Ushiba, Junichi",
        "Kawakami, Michiyuki",
        "Ohwa, Tomomi",
        "Hagimura, Kazuto",
        "Ogura, Miho",
        "Okuyama, Kohei",
        "Fujiwara, Toshiyuki",
        "Liu, Meigen"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.2196/12339",
      "keywords": [
        "@UI",
        "N electroencephalography",
        "N robotics",
        "N neurofeedback",
        "N neural plasticity",
        "N electric stimulation",
        "N hemiplegia",
        "N brain-computer interfaces",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "e12339",
      "publication": {
        "category": "Journal",
        "cite_score": 2.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1929-0748",
        "publisher": "JMIR Publications Inc.",
        "sjr": 0.528,
        "snip": 0.631,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "JMIR research protocols"
      },
      "publication_date": "2018-12-06",
      "selected": false,
      "title": "Evaluating the Effectiveness and Safety of the Electroencephalogram-Based Brain-Machine Interface Rehabilitation System for Patients With Severe Hemiparetic Stroke: Protocol for a Randomized Controlled Trial (BEST-BRAIN Trial).",
      "urls": []
    },
    {
      "abstract": "Management of obsessive compulsive disorder (OCD) remains a challenge, particularly in individuals having co-existing psychotic symptoms. Even in patients with schizophrenia having a fair to good response in psychotic symptoms, these obsessive-compulsive symptoms defy response to antipsychotic and anti-obsessive pharmaco-therapeutic approach to a great extent. Recently developed neuromodulation techniques such as transcranial direct current stimulation (tDCS) can serve a viable and effective approach to manage such cases. The present paper documents the first utilization of tDCS (cathode: supplementary motor area; anode: right occipital cortex) as an add-on approach to pharmacotherapy to manage co-morbid OCD in a case of chronic schizophrenia. \u00c2\u00a9 2018",
      "authors": [
        "Verma, R.",
        "Kumar, N.",
        "Mahapatra, A.",
        "Shah, B."
      ],
      "categories": null,
      "citations": 7,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1016/j.ajp.2018.10.013",
      "keywords": [
        "Compulsive",
        "Obsessive",
        "tDCS",
        "Transcranial",
        "Schizophrenia"
      ],
      "number_of_pages": 3,
      "pages": "9-11",
      "publication": {
        "category": "Journal",
        "cite_score": 10.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "18762018",
        "publisher": "Elsevier",
        "sjr": 1.326,
        "snip": 1.619,
        "subject_areas": [
          "Psychology (all)",
          "Psychiatry and Mental Health"
        ],
        "title": "Asian Journal of Psychiatry"
      },
      "publication_date": "2018-12-01",
      "selected": false,
      "title": "Effectiveness of tDCS augmentation for co-morbid obsessive compulsive disorder in chronic schizophrenia: A case report",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85055110822&origin=inward"
      ]
    },
    {
      "abstract": "Attention biases towards threat signals have been linked to the etiology and symptomatology of social anxiety disorder (SAD). Dysfunction of the dorsolateral prefrontal cortex (dlPFC) may contribute to attention biases in anxious individuals. The aim of this study was to investigate the feasibility of near-infrared spectroscopy (NIRS) neurofeedback (NF) training\u00e2\u0080\u0094targeting the dlPFC\u00e2\u0080\u0094and its effects on threat-related attention biases of individuals with SAD. 12 individuals with SAD participated in the NIRS-NF training lasting 6\u00e2\u0080\u00938 weeks and including a total of 15 sessions. NF performance increased significantly, while the attention bias towards threat-related stimuli and SAD symptom severity decreased after the training. The individual increase in neurofeedback performance as well as the individual decrease in SAD symptom severity was correlated with decreased responses to social threat signals in the cerebral attention system. Thus, this pilot study does not only demonstrate that NIRS-based NF is feasible in SAD patients, but also may be a promising method to investigate the causal role of the dlPFC in attention biases in SAD. Its effectiveness as a treatment tool might be examined in future studies. \u00c2\u00a9 2018, Springer-Verlag GmbH Austria, part of Springer Nature.",
      "authors": [
        "Kimmig, Ann-Christin S",
        "Dresler, Thomas",
        "Hudak, Justin",
        "Haeussinger, Florian B",
        "Wildgruber, Dirk",
        "Fallgatter, Andreas J",
        "Ehlis, Ann-Christine",
        "Kreifelts, Benjamin"
      ],
      "categories": null,
      "citations": 18,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1007/s00702-018-1954-5",
      "keywords": [
        "N Social anxiety disorder",
        "@UI",
        "N DlPFC",
        "N Attention bias",
        "N Near-infrared spectroscopy",
        "N Laughter",
        "#text"
      ],
      "number_of_pages": 11,
      "pages": "1175-1185",
      "publication": {
        "category": "Journal",
        "cite_score": 6.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1435-1463",
        "publisher": "Springer Verlag",
        "sjr": 0.875,
        "snip": 1.061,
        "subject_areas": [
          "Neurology (clinical)",
          "Psychiatry and Mental Health",
          "Biological Psychiatry",
          "Neurology"
        ],
        "title": "Journal of neural transmission (Vienna, Austria : 1996)"
      },
      "publication_date": "2018-11-29",
      "selected": true,
      "title": "Feasibility of NIRS-based neurofeedback training in social anxiety disorder: behavioral and neural correlates.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85057583700&origin=inward"
      ]
    },
    {
      "abstract": "OBJECTIVE: UNASSIGNED This paper reviews the history of electroconvulsive therapy (ECT) with an emphasis on the Australian context over the past 30\u2009years. The review includes data collection, the contribution of the RANZCP, and changes in legislation.\nCONCLUSION: UNASSIGNED ECT remains the most effective treatment for severe depression. Since the 1950s efforts have been made to make it more effective, tolerable and acceptable. Over the same period, significant social and political forces have acted to have the practice of ECT restricted or banned. Psychiatrists, through the RANZCP and other bodies, have the responsibility to promote quality ECT practice, advocate for patients, carers, and clinicians, counter inaccurate negative portrayals, and lobby for balanced legislation for ECT and other neurostimulation.",
      "authors": [
        "Clarke, Patrick"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1177/1039856218815753",
      "keywords": [
        "N major depressive disorder",
        "D016428 Journal Article",
        "D016454 Review",
        "N RANZCP",
        "D016456 Historical Article",
        "N electroconvulsive therapy",
        "N legislation",
        "N history"
      ],
      "number_of_pages": 3,
      "pages": "53-55",
      "publication": {
        "category": "Journal",
        "cite_score": 2.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1440-1665",
        "publisher": "SAGE Publications Ltd",
        "sjr": 0.635,
        "snip": 0.777,
        "subject_areas": [
          "Psychiatry and Mental Health"
        ],
        "title": "Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists"
      },
      "publication_date": "2018-11-26",
      "selected": false,
      "title": "Hip Hip Hooray, ECT turns 80!",
      "urls": []
    },
    {
      "abstract": "AIM OBJECTIVE Excessive use of online games can have negative influences on mental health and daily functioning. Although the effects of transcranial direct current stimulation (tDCS) have been investigated for the treatment of addiction, it has not been evaluated for excessive online game use. This study aimed to investigate the feasibility and tolerability of tDCS over the dorsolateral prefrontal cortex (DLPFC) in online gamers.\nMETHODS METHODS 18 A total of 15 online gamers received 12 active tDCS sessions over the DLPFC (anodal left/cathodal right, 2\u00a0mA for 30\u00a0min, 3 times per week for 4 weeks). Before and after tDCS sessions, all participants underwent F-\ufb02uoro-2-deoxyglucose positron emission tomography scans and completed the Internet Addiction Test (IAT), Brief Self Control Scale (BSCS), and Beck Depression Inventory-II (BDI-II).\nRESULTS RESULTS After tDCS sessions, weekly hours spent on games (p\u2009=\u2009.02) and scores of IAT (p\u2009<\u2009.001) and BDI-II (p\u2009=\u2009.01) were decreased, whereas BSCS score was increased (p\u2009=\u2009.01). Increases in self-control were associated with decreases in both addiction severity (p\u2009=\u2009.002) and time spent on games (p\u2009=\u2009.02). Moreover, abnormal right-greater-than-left asymmetry of regional cerebral glucose metabolism in the DLPFC was partially alleviated (p\u2009=\u2009.04).\nCONCLUSIONS CONCLUSIONS Our preliminary results suggest that tDCS may be useful for reducing online game use by improving interhemispheric balance of glucose metabolism in the DLPFC and enhancing self-control. Larger sham-controlled studies with longer follow-up period are warranted to validate the efficacy of tDCS in gamers.",
      "authors": [
        "Lee, Sang Hoon",
        "Im, Jooyeon Jamie",
        "Oh, Jin Kyoung",
        "Choi, Eun Kyoung",
        "Yoon, Sujung",
        "Bikson, Marom",
        "Song, In-Uk",
        "Jeong, Hyeonseok",
        "Chung, Yong-An"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1556/2006.7.2018.107",
      "keywords": [
        "@UI",
        "N regional cerebral metabolic rate of glucose",
        "N positron emission tomography",
        "N online game",
        "N self-control",
        "N dorsolateral prefrontal cortex",
        "N transcranial direct current stimulation",
        "#text"
      ],
      "number_of_pages": 5,
      "pages": "1166-1170",
      "publication": {
        "category": "Journal",
        "cite_score": 11.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2063-5303",
        "publisher": "Akademiai Kiado",
        "sjr": 1.918,
        "snip": 1.966,
        "subject_areas": [
          "Medicine (miscellaneous)",
          "Psychiatry and Mental Health",
          "Clinical Psychology"
        ],
        "title": "Journal of behavioral addictions"
      },
      "publication_date": "2018-11-12",
      "selected": false,
      "title": "Transcranial direct current stimulation for online gamers: A prospective single-arm feasibility study.",
      "urls": []
    },
    {
      "abstract": "Modulating the function of the insular cortex could be a novel therapeutic strategy to treat addiction to a variety of drugs of abuse as this region has been implicated in mediating drug reward and addictive processes. The recent advent of the H-coil has permitted the targeting of deeper brain structures which was not previously feasible. The goal of this study was to bilaterally target the insular region using the H-coil with repetitive Transcranial Magnetic Stimulation (rTMS) and subsequently measure changes in dopamine levels using Positron Emission Tomography (PET) with [11C]-(+)-propyl-hexahydro-naphtho-oxazin (PHNO). This was a within-subject, crossover, blinded and sham-controlled pilot study. Eight healthy, right-handed subjects, aged 19-45, participated in the investigation. All subjects underwent 3 PHNO-PET scans preceded by rTMS (sham, 1\u00a0Hz or 10\u00a0Hz), on 3 separate days. Low frequency rTMS (1\u00a0Hz), targeting the insular cortex, significantly decreased dopamine levels in the substantia nigra, sensorimotor striatum and associative striatum. Replicating this study in tobacco smokers or alcoholics would be a logical follow-up to assess whether H-coil stimulation of the bilateral insula can be employed as a treatment option for addiction. Trial registration: NCT02212405.",
      "authors": [
        "Malik, Saima",
        "Jacobs, Mark",
        "Cho, Sang-Soo",
        "Boileau, Isabelle",
        "Blumberger, Daniel",
        "Heilig, Markus",
        "Wilson, Alan",
        "Daskalakis, Zafiris J",
        "Strafella, Antonio P",
        "Zangen, Abraham",
        "Le Foll, Bernard"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1007/s11682-017-9800-1",
      "keywords": [
        "N Insula",
        "N Dopamine",
        "D016428 Journal Article",
        "N PHNO",
        "N H-coil",
        "D016449 Randomized Controlled Trial",
        "N Deep rTMS",
        "N PET"
      ],
      "number_of_pages": 12,
      "pages": "1306-1317",
      "publication": {
        "category": "Journal",
        "cite_score": 6.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1931-7565",
        "publisher": "Springer New York",
        "sjr": 1.002,
        "snip": 1.07,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Behavioral Neuroscience",
          "Psychiatry and Mental Health",
          "Neurology",
          "Radiology, Nuclear Medicine and Imaging",
          "Neurology (clinical)",
          "Cellular and Molecular Neuroscience"
        ],
        "title": "Brain imaging and behavior"
      },
      "publication_date": "2018-10-01",
      "selected": false,
      "title": "11 Deep TMS of the insula using the H-coil modulates dopamine release: a crossover [C] PHNO-PET pilot trial in healthy humans.",
      "urls": []
    },
    {
      "abstract": "Angry outbursts during interpersonal provocations may lead to violence and prevails in numerous pathological conditions. In the anger-infused Ultimatum Game (aiUG), unfair monetary offers accompanied by written provocations induce anger. Rejection of such offers relates to aggression, whereas acceptance to anger regulation. We previously demonstrated the involvement of the ventro-medial prefrontal cortex (vmPFC) in accepting unfair offers and attenuating anger during an aiUG, suggestive of its role in anger regulation. Here, we aimed to enhance anger regulation by facilitating vmPFC activity during anger induction, using anodal transcranial direct current stimulation (tDCS) and simultaneously with functional Magnetic Resonance Imaging to validate modulation of vmPFC activity. In a cross-over, sham-controlled, double-blind study, participants (N\u00a0=\u00a025) were each scanned twice, counterbalancing sham and active tDCS applied during administration of the aiUG. Outcome measures included the effect of active versus sham stimulation on vmPFC activity, unfair offers' acceptance rates, self-reported anger, and aggressive behavior in a subsequent reactive aggression paradigm. Results indicate that active stimulation led to increased vmPFC activity during the processing of unfair offers, increased acceptance rates of these offers, and mitigated the increase in self-reported anger following the aiUG. We also noted a decrease in subsequent aggressive behavior following active stimulation, but only when active stimulation was conducted in the first experimental session. Finally, an exploratory finding indicated that participants with a stronger habitual tendency to use suppression as an emotion regulation strategy, reported less anger following the aiUG in the active compared to sham stimulation conditions. Findings support a potential causal link between vmPFC functionality and the experience and expression of anger, supporting vmPFC's role in anger regulation, and providing a promising avenue for reducing angry and aggressive outbursts during interpersonal provocations in various psychiatric and medical conditions.",
      "authors": [
        "Gilam, Gadi",
        "Abend, Rany",
        "Gurevitch, Guy",
        "Erdman, Alon",
        "Baker, Halen",
        "Ben-Zion, Ziv",
        "Hendler, Talma"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.cortex.2018.09.010",
      "keywords": [
        "D016428 Journal Article",
        "N vmPFC",
        "D052060 Research Support, N.I.H., Intramural",
        "D052061 Research Support, N.I.H., Extramural",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Ultimatum Game",
        "N Aggression",
        "N Anger",
        "N Taylor Aggression Paradigm"
      ],
      "number_of_pages": 15,
      "pages": "156-170",
      "publication": {
        "category": "Journal",
        "cite_score": 7.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1973-8102",
        "publisher": "Masson SpA",
        "sjr": 1.303,
        "snip": 1.241,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Experimental and Cognitive Psychology",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Cortex; a journal devoted to the study of the nervous system and behavior"
      },
      "publication_date": "2018-09-27",
      "selected": false,
      "title": "Attenuating anger and aggression with neuromodulation of the vmPFC: A simultaneous tDCS-fMRI study.",
      "urls": []
    },
    {
      "abstract": "It has been postulated that gaining control over activity in the dorsolateral prefrontal cortex (DLPFC), a key region of the working memory brain network, may be beneficial for cognitive performance and treatment of certain psychiatric disorders. Several studies have reported that, with neurofeedback training, subjects can learn to increase DLPFC activity. However, improvement of dynamic control in terms of switching between low and high activity in DLPFC brain states may potentially constitute more effective self-regulation. Here, we report on feasibility of obtaining dynamic control over DLPFC, meaning the ability to both in- and decrease activity at will, within a single functional MRI scan session. Two groups of healthy volunteers (N\u202f=\u202f24) were asked to increase and decrease activity in the left DLPFC as often as possible during fMRI scans (at 7\u00a0Tesla), while receiving real-time visual feedback. The experimental group practiced with real-time feedback, whereas the control group received sham feedback. The experimental group significantly increased the speed of intentionally alternating DLPFC activity, while performance of the control group did not change. Analysis of the characteristics of the BOLD signal during successful trials revealed that training with neurofeedback predominantly reduced the time for the DLPFC to return to baseline after activation. These results provide a preliminary indication that people may be able to learn to dynamically down-regulate the level of physiological activity in the DLPFC, and may have implications for psychiatric disorders where DLPFC plays a role.",
      "authors": [
        "Van den Boom, Max Alexander",
        "Jansma, Johan Martijn",
        "Ramsey, Nick Franciscus"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.euroneuro.2018.08.508",
      "keywords": [
        "N fMRI",
        "D016428 Journal Article",
        "N Working memory function",
        "N Biofeedback",
        "N Activity regulation",
        "N Dorsolateral prefrontal cortex",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Neurofeedback"
      ],
      "number_of_pages": 12,
      "pages": "1194-1205",
      "publication": {
        "category": "Journal",
        "cite_score": 8.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1873-7862",
        "publisher": "Elsevier",
        "sjr": 1.442,
        "snip": 1.185,
        "subject_areas": [
          "Psychiatry and Mental Health",
          "Neurology",
          "Biological Psychiatry",
          "Neurology (clinical)",
          "Pharmacology",
          "Pharmacology (medical)"
        ],
        "title": "European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology"
      },
      "publication_date": "2018-09-11",
      "selected": false,
      "title": "Rapid acquisition of dynamic control over DLPFC using real-time fMRI feedback.",
      "urls": []
    },
    {
      "abstract": "A priori normative beliefs, the precondition of social norm compliance that reflects culture and values, are considered unique to human social behavior. Previous studies related to the ultimatum game revealed that right lateral prefrontal cortex (rLPFC) has no stimulation effects on normative beliefs. However, no research has focused on the effects of a priori belief on the rLPFC in voluntary cooperation attached to the public good (PG) game. In this study, we used a linear asymmetric PG to confirm the influence of the rLPFC on a priori normative beliefs without threats of external punishment through transcranial direct current stimulation (tDCS). Participants engaged via computer terminals in groups of four (i.e., two high-endowment players with 35G$ and two low-endowment players with 23G$). They were anonymous and had no communication during the entire process. They were randomly assigned to receive 15 min of either anodal, cathodal, or sham stimulation and then asked to answer questions concerning a priori normative beliefs (norm.belief and pg.belief). Results suggested that anodal/cathodal tDCS significantly (P < 0.001) shifted the participants' a priori normative beliefs in opposite directions compared to the shift in the sham group. In addition, different identities exhibited varying degrees of change (28.80-54.43%). These outcomes provide neural evidence of the rLPFC mechanism's effect on the normative beliefs in voluntary cooperation based on the PG framework. \u00c2\u00a9 2018 Li, Liu, Yin, Li, Wang, Niu and Zhu.",
      "authors": [
        "Li, Jianbiao",
        "Liu, Xiaoli",
        "Yin, Xile",
        "Li, Shuaiqi",
        "Wang, Pengcheng",
        "Niu, Xiaofei",
        "Zhu, Chengkang"
      ],
      "categories": null,
      "citations": 1,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.3389/fnins.2018.00606",
      "keywords": [
        "@UI",
        "N identity",
        "N voluntary cooperation",
        "N a priori normative beliefs",
        "N rLPFC",
        "#text",
        "N transcranial direct current stimulation"
      ],
      "number_of_pages": null,
      "pages": "606",
      "publication": {
        "category": "Journal",
        "cite_score": 6.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1662-4548",
        "publisher": "Frontiers Media S.A.",
        "sjr": 1.161,
        "snip": 1.221,
        "subject_areas": [
          "Neuroscience (all)"
        ],
        "title": "Frontiers in neuroscience"
      },
      "publication_date": "2018-08-31",
      "selected": false,
      "title": "a priori Transcranial Direct Current Stimulation of the Right Lateral Prefrontal Cortex Changes  Normative Beliefs in Voluntary Cooperation.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85052886590&origin=inward"
      ]
    },
    {
      "abstract": "In order to act in a socially acceptable way, the ability to forgive is indispensable. It has been suggested that forgiveness relies on cognitive control, more specifically inhibition. In this study, we combined an ultimatum game (UG) and a dictator game (DG) with inhibitory, continuous theta-burst stimulation (cTBS; verum vs. placebo, within-subjects design) of the right dorsolateral prefrontal cortex (DLPFC) to investigate the effect of reduced cognitive control on forgiveness. To this end, participants played an UG against fair and unfair opponents, where they had to accept or reject (fair and unfair) monetary offers, and then received a cTBS prior to playing a DG against the same opponents with reversed roles. The participants now had the possibility to forgive the unfair opponents (allocation of a fair amount of money) or to take revenge whereby the cTBS effects were assessed with functional near-infrared spectroscopy. Following verum cTBS, participants allocated significantly less money to their unfair opponents than in the placebo cTBS condition. Also, reaction times (RTs) differed significantly between verum and placebo cTBS for unfair opponents (higher RTs following verum stimulation) but not for fair opponents. These results strongly indicate that cognitive control is a fundamental requirement for overcoming unwanted emotional responses.",
      "authors": [
        "Maier, Moritz Julian",
        "Rosenbaum, David",
        "Haeussinger, Florian Benedikt",
        "Br\u00fcne, Martin",
        "Enzi, Bj\u00f6rn",
        "Plewnia, Christian",
        "Fallgatter, Andreas Jochen",
        "Ehlis, Ann-Christine"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.neuroimage.2018.08.065",
      "keywords": [
        "N Revenge",
        "N Cognitive control",
        "D016428 Journal Article",
        "N TMS",
        "N fNIRS",
        "N Forgiveness",
        "D013485 Research Support, Non-U.S. Gov't",
        "N DLPFC"
      ],
      "number_of_pages": 7,
      "pages": "769-775",
      "publication": {
        "category": "Journal",
        "cite_score": 11.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1095-9572",
        "publisher": "Academic Press Inc.",
        "sjr": 2.512,
        "snip": 1.782,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Neurology"
        ],
        "title": "NeuroImage"
      },
      "publication_date": "2018-08-28",
      "selected": false,
      "title": "Forgiveness and cognitive control - Provoking revenge via theta-burst-stimulation of the DLPFC.",
      "urls": []
    },
    {
      "abstract": "Background: To determine the effect of preconception body mass index (BMI) and/or gestational weight gain (GWG) on the occurrence of sleep disorders over the whole pregnancy. Methods: A sample of 2,366 pregnant women, recruited in their 1st trimester (TM), was evaluated until delivery for their sleeping characteristics, using the Pittsburgh Sleep Quality Index (PSQI). Mixed or multinomial logistic modeling was applied, as appropriate. Results: When compared with TM 1, PSQI score was the lowest at TM 2 (\u00ce\u00b2 = -1.03; 95% CI: -1.17 to -0.89) and highest in TM 3 (\u00ce\u00b2 = 0.27; 95% CI: 0.10-0.45). Obese (\u00ce\u00b2 = 0.48; 95% CI: 0.17-0.78) and overweight women (\u00ce\u00b2 = 0.24; 95% CI: 0.00-0.48) exhibited an overall greater PSQI than normal-weight women over the whole pregnancy. When sociodemographic factors were accounted for, the effect size was reduced by 25% among obese women (\u00ce\u00b2 = 0.36; 95% CI: 0.06-0.68), but was no more not significant in overweight women (\u00ce\u00b2 = 0.06; 95% CI: -0.17 to 0.30). Both obese and overweight women still exhibited, although at a lower extend, a greater PSQI than normal-weight women. Further adjustment for GWG had no effect on these observations. Obese women almost had a four-fold increased risk (OR = 3.89; 95% CI: 2.50-6.06) of being snorers in the three TMs. While GWG had only a minor effect (aOR = 3.83; 95% CI: 2.43-6.03), sociodemographic factors increased the odds of being habitual snorer (aOR = 4.04; 95% CI: 2.57-6.35). Conclusions: High prepregnancy BMI together with sociodemographic correlates appear as the most critical for sleep disturbances across pregnancy. GWG is of marginal importance, especially regarding snoring. These findings confirm the importance of considering the initial body weight status of women in tailoring sleep hygiene advises irrespective of the recommendations for weight gain during pregnancy. The results also underscore the need to providing as early as possible during a pregnancy, supportive tools to ethnic minorities, multiparous, and women from deprived socioeconomic neighborhoods. \u00c2\u00a9 Copyright 2019, Mary Ann Liebert, Inc., publishers 2019.",
      "authors": [
        "Guinhouya, Benjamin C",
        "Bisson, Michelle",
        "Dubois, Lise",
        "S\u00e9ri\u00e8s, Fr\u00e9d\u00e9ric",
        "Kimoff, John R",
        "Fraser, William D",
        "Marc, Isabelle"
      ],
      "categories": null,
      "citations": 12,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1089/jwh.2017.6892",
      "keywords": [
        "N weight gain",
        "N ethnicity",
        "D016428 Journal Article",
        "N snoring",
        "D013485 Research Support, Non-U.S. Gov't",
        "N social inequality",
        "N obesity"
      ],
      "number_of_pages": 9,
      "pages": "535-543",
      "publication": {
        "category": "Journal",
        "cite_score": 5.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1931-843X",
        "publisher": "Mary Ann Liebert Inc.",
        "sjr": 1.253,
        "snip": 1.295,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "Journal of women's health (2002)"
      },
      "publication_date": "2018-08-01",
      "selected": false,
      "title": "Body Weight Status and Sleep Disturbances During Pregnancy: Does Adherence to Gestational Weight Gain Guidelines Matter?",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85064249605&origin=inward"
      ]
    },
    {
      "abstract": "Neurofeedback (NFB) enables the voluntary regulation of brain activity, with promising applications to enhance and recover emotion and cognitive processes, and their underlying neurobiology. It remains unclear whether NFB can be used to aid and sustain complex emotions, with ecological validity implications. We provide a technical proof of concept of a novel real-time functional magnetic resonance imaging (rtfMRI) NFB procedure. Using rtfMRI-NFB, we enabled participants to voluntarily enhance their own neural activity while they experienced complex emotions. The rtfMRI-NFB software (FRIEND Engine) was adapted to provide a virtual environment as brain computer interface (BCI) and musical excerpts to induce two emotions (tenderness and anguish), aided by participants' preferred personalized strategies to maximize the intensity of these emotions. Eight participants from two experimental sites performed rtfMRI-NFB on two consecutive days in a counterbalanced design. On one day, rtfMRI-NFB was delivered to participants using a region of interest (ROI) method, while on the other day using a support vector machine (SVM) classifier. Our multimodal VR/NFB approach was technically feasible and robust as a method for real-time measurement of the neural correlates of complex emotional states and their voluntary modulation. Guided by the color changes of the virtual environment BCI during rtfMRI-NFB, participants successfully increased in real time, the activity of the septo-hypothalamic area and the amygdala during the ROI based rtfMRI-NFB, and successfully evoked distributed patterns of brain activity classified as tenderness and anguish during SVM-based rtfMRI-NFB. Offline fMRI analyses confirmed that during tenderness rtfMRI-NFB conditions, participants recruited the septo-hypothalamic area and other regions ascribed to social affiliative emotions (medial frontal / temporal pole and precuneus). During anguish rtfMRI-NFB conditions, participants recruited the amygdala and other dorsolateral prefrontal and additional regions associated with negative affect. These findings were robust and were demonstrable at the individual subject level, and were reflected in self-reported emotion intensity during rtfMRI-NFB, being observed with both ROI and SVM methods and across the two sites. Our multimodal VR/rtfMRI-NFB protocol provides an engaging tool for brain-based interventions to enhance emotional states in healthy subjects and may find applications in clinical conditions associated with anxiety, stress and impaired empathy among others.",
      "authors": [
        "Lorenzetti, Valentina",
        "Melo, Bruno",
        "Bas\u00edlio, Rodrigo",
        "Suo, Chao",
        "Y\u00fccel, Murat",
        "Tierra-Criollo, Carlos J",
        "Moll, Jorge"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3389/fneur.2018.00390",
      "keywords": [
        "N fMRI",
        "@UI",
        "N virtual environments",
        "N neurofeedback",
        "N support vector machine",
        "N region of interest",
        "N virtual reality",
        "N BCI",
        "#text",
        "N emotion regulation"
      ],
      "number_of_pages": null,
      "pages": "390",
      "publication": {
        "category": "Journal",
        "cite_score": 4.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1664-2295",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.978,
        "snip": 1.151,
        "subject_areas": [
          "Neurology (clinical)",
          "Neurology"
        ],
        "title": "Frontiers in neurology"
      },
      "publication_date": "2018-07-24",
      "selected": false,
      "title": "Emotion Regulation Using Virtual Environments and Real-Time fMRI Neurofeedback.",
      "urls": []
    },
    {
      "abstract": "Social norms play an essential role in human interactions and the development of the evolution of human history. Extensive studies corroborate that compliance with social norms typically requires a punishment threat as almost always specific individuals have self-interests that tempt them to violate the norm. Neural imaging studies demonstrate that lateral orbitofrontal cortex (LOFC) and right dorsolateral prefrontal cortex (rDLPFC) are activated when individuals decide to increase social norm compliance when punishment is possible. Moreover, rDLPFC is affirmed to be involved in social norm compliance with or without external punishment threats in a series of transcranial direct current stimulation (tDCS) research. However, these neuroscience studies are based on the ultimatum game (UG) in which the decision-making power between the proposer and the responder is unequal, and no studies support the causal relationship between rDLPFC and voluntary cooperative norms compliance among the equal decision-making power of subjects. Whether modulating the excitability of rDLPFC, which plays a role in norm compliance, alters the extent of compliance with voluntary cooperative norms under equal decision-making power and how norms from different types with asymmetric endowment influence compliance remain unknown. The present study aimed to provide evidence of a direct link between the neural and behavioral results through the application of tDCS over rDLPFC on compliance with voluntary cooperative norms under equal decision-making power. Results verified that activating rDLPFC altered voluntary cooperative norms compliance of all our participants and significant effect over different initial endowments was observed. The role of norm.own and norm.other in compliance was changed in the anodal treatment. Findings validate that enhancing the excitability of the rDLPFC using tDCS leads to high compliance in voluntary cooperation and this effect is specific to equal decision-making power rather than unequal decision-making power. \u00c2\u00a9 2018 Li, Liu, Yin, Li, Wang, Niu and Zhu.",
      "authors": [
        "Li, Jianbiao",
        "Liu, Xiaoli",
        "Yin, Xile",
        "Li, Shuaiqi",
        "Wang, Guangrong",
        "Niu, Xiaofei",
        "Zhu, Chengkang"
      ],
      "categories": null,
      "citations": 5,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.3389/fnhum.2018.00265",
      "keywords": [
        "N right dorsolateral prefrontal cortex",
        "N equal decision-making power",
        "N voluntary cooperative norm",
        "#text",
        "N norm compliance",
        "N transcranial direct current stimulation",
        "@UI"
      ],
      "number_of_pages": null,
      "pages": "265",
      "publication": {
        "category": "Journal",
        "cite_score": 4.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1662-5161",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.787,
        "snip": 1.033,
        "subject_areas": [
          "Psychiatry and Mental Health",
          "Neurology",
          "Biological Psychiatry",
          "Neuropsychology and Physiological Psychology",
          "Behavioral Neuroscience"
        ],
        "title": "Frontiers in human neuroscience"
      },
      "publication_date": "2018-07-03",
      "selected": false,
      "title": "Transcranial Direct Current Stimulation Altered Voluntary Cooperative Norms Compliance Under Equal Decision-Making Power.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85054790853&origin=inward"
      ]
    },
    {
      "abstract": "Individuals with autism and intellectual impairments tend to be excluded from research due to their difficulties with methodological compliance. This study focuses on using Teaching with Acoustic Guidance\u00e2\u0080\u0094TAGteach\u00e2\u0080\u0094to behaviorally prepare children with autism and a IQ \u00e2\u0089\u00a4 80 to participate in a study on neurofeedback training (NFT). Seven children (ages 6\u00e2\u0080\u00938) learned the prerequisite skills identified in a task analysis in an average of 5\u00c2 h of TAGteach training, indicating that this is a feasible method of preparing intellectually-impaired children with autism to participate in NFT and task-dependent electroencephalography measures. TAGteach may thus have the potential to augment this population\u00e2\u0080\u0099s ability to participate in less accessible treatments and behavioral neuroscientific studies. \u00c2\u00a9 2018, Springer Science+Business Media, LLC, part of Springer Nature.",
      "authors": [
        "LaMarca, Kristen",
        "Gevirtz, Richard",
        "Lincoln, Alan J",
        "Pineda, Jaime A"
      ],
      "categories": null,
      "citations": 6,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1007/s10803-018-3466-4",
      "keywords": [
        "N Intellectual impairment",
        "N Mu rhythms",
        "N Conditioned reinforcement",
        "N Mirror neurons",
        "N Low-functioning",
        "#text",
        "N Neurofeedback",
        "N Autism",
        "N TAGteach",
        "N Auditory secondary reinforcement",
        "@UI"
      ],
      "number_of_pages": 11,
      "pages": "2090-2100",
      "publication": {
        "category": "Journal",
        "cite_score": 7.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1573-3432",
        "publisher": "Springer New York",
        "sjr": 1.196,
        "snip": 1.863,
        "subject_areas": [
          "Developmental and Educational Psychology"
        ],
        "title": "Journal of autism and developmental disorders"
      },
      "publication_date": "2018-06-01",
      "selected": true,
      "title": "Facilitating Neurofeedback in Children with Autism and Intellectual Impairments Using TAGteach.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85041135263&origin=inward"
      ]
    },
    {
      "abstract": "There is no accepted pathology to autism spectrum disorders (ASD) but research suggests the presence of an altered excitatory/inhibitory (E/I) bias in the cerebral cortex. Repetitive transcranial magnetic stimulation (rTMS) offers a non-invasive means of modulating the E/I cortical bias with little in terms of side effects. In this study, 124 high functioning ASD children (IQ > 80, <18 years of age) were recruited and assigned using randomization to either a waitlist group or one of three different number of weekly rTMS sessions (i.e., 6, 12, and 18). TMS consisted of trains of 1.0 Hz frequency pulses applied over the dorsolateral prefrontal cortex (DLPFC). The experimental task was a visual oddball with illusory Kanizsa figures. Behavioral response variables included reaction time and error rate along with such neurophysiological indices such as stimulus and response-locked event-related potentials (ERP). One hundred and twelve patients completed the assigned number of TMS sessions. Results showed significant changes from baseline to posttest period in the following measures: motor responses accuracy [lower percentage of committed errors, slower latency of commission errors and restored normative post-error reaction time slowing in both early and later-stage ERP indices, enhanced magnitude of error-related negativity (ERN), improved error monitoring and post-error correction functions]. In addition, screening surveys showed significant reductions in aberrant behavior ratings and in both repetitive and stereotypic behaviors. These differences increased with the total number of treatment sessions. Our results suggest that rTMS, particularly after 18 sessions, facilitates cognitive control, attention and target stimuli recognition by improving discrimination between task-relevant and task-irrelevant illusory figures in an oddball test. The noted improvement in executive functions of behavioral performance monitoring further suggests that TMS has the potential to target core features of ASD.",
      "authors": [
        "Sokhadze, Estate M",
        "Lamina, Eva V",
        "Casanova, Emily L",
        "Kelly, Desmond P",
        "Opris, Ioan",
        "Tasman, Allan",
        "Casanova, Manuel F"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3389/fnsys.2018.00020",
      "keywords": [
        "N ERP",
        "N TMS",
        "N autism spectrum disorder",
        "#text",
        "N oddball task",
        "N aberrant and repetitive behaviors",
        "N executive functions",
        "N reaction time",
        "@UI"
      ],
      "number_of_pages": null,
      "pages": "20",
      "publication": {
        "category": "Journal",
        "cite_score": 5.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1662-5137",
        "publisher": "Frontiers Media S.A.",
        "sjr": 1.07,
        "snip": 1.027,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Developmental Neuroscience",
          "Neuroscience (miscellaneous)",
          "Cellular and Molecular Neuroscience"
        ],
        "title": "Frontiers in systems neuroscience"
      },
      "publication_date": "2018-05-28",
      "selected": false,
      "title": "Exploratory Study of rTMS Neuromodulation Effects on Electrocortical Functional Measures of Performance in an Oddball Test and Behavioral Symptoms in Autism.",
      "urls": []
    },
    {
      "abstract": "Transcranial direct current stimulation (tDCS) delivered in multiple sessions can reduce symptom burden, but access of chronically ill patients to tDCS studies is constrained by the burden of office-based tDCS administration. Expanded access to this therapy can be accomplished through the development of interventions that allow at-home tDCS applications. Objective: We describe the development and initial feasibility assessment of a novel intervention for the chronically ill that combines at-home tDCS with telehealth support. Methods: In the developmental phase, the tDCS procedure was adjusted for easy application by patients or their informal caregivers at home, and a tDCS protocol with specific elements for enhanced safety and remote adherence monitoring was created. Lay language instructional materials were written and revised based on expert feedback. The materials were loaded onto a tablet allowing for secure video-conferencing. The telehealth tablet was paired with an at-home tDCS device that allowed for remote dose control via electronic codes dispensed to patients prior to each session. tDCS was delivered in two phases: once daily on 10 consecutive days, followed by an as needed regimen for 20 days. Initial feasibility of this tDCS-telehealth system was evaluated in four patients with advanced chronic illness and multiple symptoms. Change in symptom burden and patient satisfaction were assessed with the Condensed Memorial Symptom Assessment Scale (CMSAS) and a tDCS user survey. Results: The telehealth-tDCS protocol includes one home visit and has seven patient-tailored elements and six elements enhancing safety monitoring. Replicable electrode placement at home without 10\u00e2\u0080\u009320 EEG measurement is achieved via a headband that holds electrodes in a pre-determined position. There were no difficulties with patients\u00e2\u0080\u0099 training, protocol adherence, or tolerability. A total of 60 tDCS sessions were applied. No session required discontinuation, and there were no adverse events. Data collection was feasible and there were no missing data. Satisfaction with the tDCS-telehealth procedure was high and the patients were comfortable using the system. Conclusion: At-home tDCS with telehealth support appears to be a feasible approach for the management of symptom burden in patients with chronic illness. Further studies to evaluate and optimize the protocol effectiveness for symptom-control outcomes are warranted. \u00c2\u00a9 2018 Riggs, Patel, Paneri, Portenoy, Bikson and Knotkova.",
      "authors": [
        "Riggs, Alexa",
        "Patel, Vaishali",
        "Paneri, Bhaskar",
        "Portenoy, Russell K",
        "Bikson, Marom",
        "Knotkova, Helena"
      ],
      "categories": null,
      "citations": 36,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.3389/fnbeh.2018.00093",
      "keywords": [
        "N non-invasive brain stimulation",
        "@UI",
        "N chronic illness",
        "N home settings",
        "N symptom management",
        "N patient-tailored protocol",
        "N at-home tDCS",
        "N transcranial direct current stimulation",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "93",
      "publication": {
        "category": "Journal",
        "cite_score": 4.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1662-5153",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.975,
        "snip": 0.965,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Behavioral Neuroscience",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Frontiers in behavioral neuroscience"
      },
      "publication_date": "2018-05-22",
      "selected": false,
      "title": "At-Home Transcranial Direct Current Stimulation (tDCS) With Telehealth Support for Symptom Control in Chronically-Ill Patients With Multiple Symptoms.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85049529375&origin=inward"
      ]
    },
    {
      "abstract": "We examined the efficacy and acceptability of non-invasive brain stimulation in adult unipolar and bipolar depression. Randomised sham-controlled trials of transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS) and theta-burst stimulation (TBS), without co-initiation of another treatment, were included. We analysed effects on response, remission, all-cause discontinuation rates and continuous depression severity measures. Fifty-six studies met our criteria for inclusion (N\u202f=\u202f3058, mean age\u202f=\u202f44.96 years, 61.73% female). Response rates demonstrated efficacy of high-frequency rTMS over the left DLPFC (OR\u202f=\u202f3.75, 95% CI [2.44; 5.75]), right-sided low-frequency rTMS (OR\u202f=\u202f7.44, 95%CI [2.06; 26.83]) bilateral rTMS (OR\u202f=\u202f3.68,95%CI [1.66; 8.13]), deep TMS (OR\u202f=\u202f1.69, 95%CI [1.003; 2.85]), intermittent TBS (OR\u202f=\u202f4.70, 95%CI [1.14; 19.38]) and tDCS (OR\u202f=\u202f4.17, 95% CI [2.25; 7.74]); but not for continuous TBS, bilateral TBS or synchronised TMS. There were no differences in all-cause discontinuation rates. The strongest evidence was for high-frequency rTMS over the left DLPFC. Intermittent TBS provides an advance in terms of reduced treatment duration. tDCS is a potential treatment for non-treatment resistant depression. To date, there is not sufficient published data available to draw firm conclusions about the efficacy and acceptability of TBS and sTMS.",
      "authors": [
        "Mutz, Julian",
        "Edgcumbe, Daniel R",
        "Brunoni, Andre R",
        "Fu, Cynthia H Y"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.neubiorev.2018.05.015",
      "keywords": [
        "N Transcranial magnetic stimulation",
        "N Theta burst stimulation",
        "D016428 Journal Article",
        "N Transcranial direct current stimulation",
        "N Brain stimulation",
        "N Systematic review",
        "N Meta-analysis",
        "N Depression",
        "D017418 Meta-Analysis",
        "D000078182 Systematic Review"
      ],
      "number_of_pages": 13,
      "pages": "291-303",
      "publication": {
        "category": "Journal",
        "cite_score": 13.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1873-7528",
        "publisher": "Elsevier Ltd.",
        "sjr": 2.599,
        "snip": 2.49,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Behavioral Neuroscience",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Neuroscience and biobehavioral reviews"
      },
      "publication_date": "2018-05-12",
      "selected": false,
      "title": "Efficacy and acceptability of non-invasive brain stimulation for the treatment of adult unipolar and bipolar depression: A systematic review and meta-analysis of randomised sham-controlled trials.",
      "urls": []
    },
    {
      "abstract": "The present case study details sensations elicited by electrical stimulation of peripheral nerve axons using an implanted nerve cuff electrode, in a participant with a transhumeral amputation. The participant uses an osseointegrated electromechanical interface, which enables skeletal attachment of the prosthesis and long-term, stable, bidirectional communication between the implanted electrodes and prosthetic arm. We focused on evoking somatosensory percepts, where we tracked and quantified the evolution of perceived sensations in the missing hand, which were evoked from electrical stimulation of the nerve, for over 2 yr. These sensations included small, pointlike areas of either vibration or pushing, to larger sensations over wider areas, indicating the recruitment of a few and many afferents, respectively. Furthermore, we used a two-alternative forced choice paradigm to measure the level of discrimination between trains of brief electrical stimuli, to gauge what the participant could reliably distinguish between. At best, the participant was able to distinguish a 0.5-Hz difference and on average acquired a 3.8-Hz just-noticeable difference at a more stringent psychophysical level. The current work shows the feasibility for long-term sensory feedback in prostheses, via electrical axonal stimulation, where small and relatively stable percepts were felt that may be used to deliver graded sensory feedback. This opens up opportunities for signaling feedback during movements (e.g., for precision grip), but also for conveying more complex cutaneous sensations, such as texture. NEW & NOTEWORTHY We demonstrate the long-term stability and generation of sensations from electrical peripheral nerve stimulation in an amputee, through an osseointegrated implant. We find that perceived tactilelike sensations could be generated for over 2 yr, in the missing hand. This is useful for prosthetic development and the implementation of feedback in artificial body parts.",
      "authors": [
        "Ackerley, Rochelle",
        "Backlund Wasling, Helena",
        "Ortiz-Catalan, Max",
        "Br\u00e5nemark, Rickard",
        "Wessberg, Johan"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1152/jn.00909.2017",
      "keywords": [
        "N hand",
        "N prosthetics",
        "D016428 Journal Article",
        "N amputation",
        "D013485 Research Support, Non-U.S. Gov't",
        "N artificial touch",
        "N electrical nerve stimulation",
        "N somatosensory"
      ],
      "number_of_pages": 5,
      "pages": "291-295",
      "publication": {
        "category": "Journal",
        "cite_score": 5.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1522-1598",
        "publisher": "American Physiological Society",
        "sjr": 1.067,
        "snip": 0.974,
        "subject_areas": [
          "Physiology",
          "Neuroscience (all)"
        ],
        "title": "Journal of neurophysiology"
      },
      "publication_date": "2018-05-09",
      "selected": false,
      "title": "Case Studies in Neuroscience: Sensations elicited and discrimination ability from nerve cuff stimulation in an amputee over time.",
      "urls": []
    },
    {
      "abstract": "Several personality disorders involve pathological behaviors that violate social norms, commonly held expectations about what ought to be done in specific situations. These symptoms usually emerge early in development, are persistent and hard to treat, and are often ego-syntonic. Here I present some recent brain stimulation studies suggesting that pathological changes in different aspects of norm-compliant behavior reflect dysfunctions of brain circuits involving distinct prefrontal brain areas. One set of studies shows that transcranial direct current stimulation of the right lateral prefrontal cortex changes the behavioral sensitivity to social incentives for norm-compliant behavior. Crucially, social norm compliance in response to such incentives could even be increased during excitatory stimulation, demonstrating that the affected neural process is a biological prerequisite for appropriate reaction to social signals that trigger norm compliance. In another set of studies, we show that stimulation of a different (more dorsal) part of the right prefrontal cortex enhances honesty in a realistic setting where participants had the opportunity to cheat for real monetary gains. Interestingly, these stimulation-induced increases in both socially cued or purely voluntary norm compliance were not linked to changes in other aspects of decision- making (such as risk or impatience), and they did not reflect changes in beliefs about what is appropriate behavior. These results suggest that disorders of distinct brain circuits may causally underlie egosyntotic changes in norm-compliant behavior. This raises the tantalizing possibility that pathologies of norm-compliant behavior may be ameliorated by interventions targeting the function of these brain circuits.",
      "authors": [
        "Ruff, Christian C"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1159/000486898",
      "keywords": [
        "D016428 Journal Article",
        "N Transcranial direct current stimulation",
        "N Brain stimulation",
        "D016454 Review",
        "N Social norms",
        "N Ego-syntonic behavior",
        "N Personality disorders"
      ],
      "number_of_pages": 5,
      "pages": "105-109",
      "publication": {
        "category": "Journal",
        "cite_score": 4.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1423-033X",
        "publisher": "S. Karger AG",
        "sjr": 1.001,
        "snip": 1.399,
        "subject_areas": [
          "Psychiatry and Mental Health",
          "Clinical Psychology"
        ],
        "title": "Psychopathology"
      },
      "publication_date": "2018-04-11",
      "selected": false,
      "title": "Brain Stimulation Studies of Social Norm Compliance: Implications for Personality Disorders?",
      "urls": []
    },
    {
      "abstract": "Background: Neurobiological research in autism spectrum disorders (ASD) has paid little attention on brain mechanisms that cause and maintain restricted and repetitive behaviors and interests (RRBIs). Evidence indicates an imbalance in the brain's reward system responsiveness to social and non-social stimuli may contribute to both social deficits and RRBIs. Thus, this study's central aim was to compare brain responsiveness to individual RRBI (i.e., circumscribed interests), with social rewards (i.e., social approval), in youth with ASD relative to typically developing controls (TDCs). Methods: We conducted a 3T functional magnetic resonance imaging (fMRI) study to investigate the blood-oxygenation-level-dependent effect of personalized circumscribed interest rewards versus social rewards in 39 youth with ASD relative to 22 TDC. To probe the reward system, we employed short video clips as reinforcement in an instrumental incentive delay task. This optimization increased the task's ecological validity compared to still pictures that are often used in this line of research. Results: Compared to TDCs, youth with ASD had stronger reward system responses for CIs mostly within the non-social realm (e.g., video games) than social rewards (e.g., approval). Additionally, this imbalance within the caudate nucleus' responsiveness was related to greater social impairment. Conclusions: The current data support the idea of reward system dysfunction that may contribute to enhanced motivation for RRBIs in ASD, accompanied by diminished motivation for social engagement. If a dysregulated reward system indeed supports the emergence and maintenance of social and non-social symptoms of ASD, then strategically targeting the reward system in future treatment endeavors may allow for more efficacious treatment practices that help improve outcomes for individuals with ASD and their families. \u00c2\u00a9 2018 The Author(s).",
      "authors": [
        "Kohls, G.",
        "Antezana, L.",
        "Mosner, M.G.",
        "Schultz, R.T.",
        "Yerys, B.E."
      ],
      "categories": null,
      "citations": 71,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1186/s13229-018-0195-7",
      "keywords": [
        "Functional magnetic resonance imaging",
        "Caudate nucleus",
        "Motivation",
        "Restricted and repetitive behaviors and interests",
        "Reward",
        "Circumscribed interests",
        "Striatum",
        "Reward system",
        "Autism spectrum disorders"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Molecular Autism"
      },
      "publication_date": "2018-01-30",
      "selected": false,
      "title": "Altered reward system reactivity for personalized circumscribed interests in autism",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85041348377&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND Healthcare-Associated Infections are a great concern for worldwide healthcare systems and represent a considerable threat to patient safety, leading to adverse clinical outcomes. A defined panel of indicators represents a key element to guide Healthcare Organizations towards identification of main gaps, implementation of effective actions and continuous improvements on Healthcare-Associated Infections prevention and control activities. A review on accreditation systems conducted by the Italian Study Group of Hospital Hygiene of the Italian Society of Hygiene Preventive Medicine and Public Health revealed a substantial heterogeneity of implemented standards and led to the development of a core set of indicators and requirements for Healthcare-Associated Infections' prevention and control within the hospital setting. The main aim of the study was to test the feasibility of the Healthcare-Associated Infections' prevention and control within the hospital setting tool to calculate performance scores on a sample of Italian Healthcare Organizations and to identify major critical issues. The potential benefits of the possibility of future implementation of the tool within Institutional Accreditation Programs is discussed.\nSTUDY DESIGN Cross sectional pilot survey.\nMETHODS The Healthcare-Associated Infections' prevention and control within the hospital setting included 96 criteria and 20 key areas including an area for outcomes indicators. For applicable criteria, standards fulfilment was evaluated according to a 4 point Likert scale. A composite score was calculated for each Healthcare Organization and five performance levels were identified. Data were further analysed by computing performance scores at the level of each area and requirement.\nRESULTS 20 Healthcare Organizations agreed to take part in this pilot study including two rehabilitative Healthcare Organizations. Among the whole sample a mean of 12.20% of requirements resulted not fulfilled, leaving space for further improvements. Critical areas were easily identified and the instrument was able to capture substantial differences between Healthcare Organizations. Only a few number of standards resulted \"Not Applicable\" (Mean = 4.71%) and most of them regarded Rehabilitative Healthcare Organizations. Mean composite performance index resulted 74.06% (SD = 16.96, range 36.30 - 94.27%); area of outcome indicators obtained a mean score of 56.17.\nCONCLUSION The Healthcare-Associated Infections' prevention and control within the hospital setting resulted an useful tool to assess Healthcare Organizations' performance in the field of Healthcare-Associated Infections prevention and control and to identify necessary actions for further improvements. The distribution of total scores by Healthcare Organizations showed a high heterogeneity. Implementation of the Healthcare-Associated Infections' prevention and control within the hospital setting tool as an institutional accreditation tool may help to drive the required harmonization at a national level of Healthcare-Associated Infections management and control strategies and overcome current substantial regional differences.",
      "authors": [
        "Tardivo, S",
        "Moretti, F",
        "Agodi, A",
        "Appignanesi, R",
        "Baldovin, T",
        "Barchitta, M",
        "Brusaferro, S",
        "Canino, R",
        "Carli, A",
        "D'Errico, M M",
        "Giuliani, G",
        "Moro, M",
        "Mura, I",
        "Nobile, M",
        "Novati, R",
        "Pasquarella, C",
        "Privitera, G",
        "Rossini, A",
        "Sodano, L",
        "Torregrossa, M V",
        "Torri, E",
        "Auxilia, F"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.7416/ai.2018.225",
      "keywords": [
        "N Performance assessment",
        "N Quality improvement",
        "N Healthcare-Associated Infections (HAIs)",
        "N Institutional accreditation",
        "#text",
        "@UI"
      ],
      "number_of_pages": 16,
      "pages": "70-85",
      "publication": {
        "category": "Journal",
        "cite_score": 3.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1120-9135",
        "publisher": "Societa Editrice Universo",
        "sjr": 0.389,
        "snip": 0.639,
        "subject_areas": [
          "Public Health, Environmental and Occupational Health",
          "Infectious Diseases"
        ],
        "title": "Annali di igiene : medicina preventiva e di comunita"
      },
      "publication_date": "2018-01-01",
      "selected": false,
      "title": "Essential strategies in HAI prevention and control: performance assessment through the implementation of the HAI-CoSIP tool of the GISIO-SItI group. A pilot study in a sample of Italian Organizations.",
      "urls": []
    },
    {
      "abstract": "This study attempts to comprehend factors influencing nurses\u00e2\u0080\u0099 continuance intention to use electronic health records (EHR) system in Jordan since they as the key service providers in healthcare services are main users of the system. Their acceptance and usage of the system are imperative to evaluate the system\u00e2\u0080\u0099s implementation success. A cross-sectional survey is conducted on the fully implemented EHR system public hospitals. Study framework is based on the extended model of the unified theory of acceptance and use of technology (UTAUT) and top management support (TMS). Results reveal effort expectancy, performance expectancy and facilitating conditions positively influence nurses\u00e2\u0080\u0099 continuance intention to use and top management support as significant and negatively related to nurses\u00e2\u0080\u0099 continuance intention to use. Results also disclose relationship between social influence and continuance intention to use as not significant. Multi-group analysis result indicates stronger relationship between effort expectancy and continuance intention to use is evident to ward nurses than special unit nurses. Findings confirm on the necessity to support new technologies specifically EHR system in hospitals and contributes to UTAUT theory through revealing the impact of top management support on continuance intention to use and establishing relevant measurement accuracy of study framework in Jordanian context. Copyright \u00c2\u00a9 2018 Inderscience Enterprises Ltd.",
      "authors": [
        "Alsyouf, A.",
        "Ishak, A.K."
      ],
      "categories": null,
      "citations": 46,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1504/IJEH.2018.092175",
      "keywords": [
        "UTAUT",
        "Electronic health records",
        "TMS",
        "Use of technology",
        "Top management support",
        "Nurses",
        "EHR",
        "Continuance intention",
        "Jordan",
        "Unified theory of acceptance"
      ],
      "number_of_pages": 36,
      "pages": "24-59",
      "publication": {
        "category": "Journal",
        "cite_score": 0.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "17418453",
        "publisher": "Inderscience Enterprises Ltd.",
        "sjr": 0.124,
        "snip": 0.393,
        "subject_areas": [
          "Health Informatics",
          "Health Policy"
        ],
        "title": "International Journal of Electronic Healthcare"
      },
      "publication_date": "2018-01-01",
      "selected": false,
      "title": "Understanding EHRs continuance intention to use from the perspectives of UTAUT: Practice environment moderating effect and top management support as predictor variables",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85048335296&origin=inward"
      ]
    },
    {
      "abstract": "Currently, cities have been increasingly demanding of their managers concerned with their ability to adapt to climate change in the face of their environmental impacts as happens with the management in the university campuses, although, with its perspectives of lower dimensions.\u00c3\u0082\u00c2 In this sense, the university can promote involvement through integrative actions with the surrounding community in order to build the educational environment of carbon reduction applicable to the resilience and city\u00c3\u00a2\u00e2\u0082\u00ac\u00e2\u0084\u00a2s sustainability.\u00c3\u0082\u00c2 This paper focuses on the Brazilian environmental public policies constitutional debate and the feasibility of encouraging legal instruments toward inclusion of educational initiatives to change the cultural environment to approach the community as an instrument to raise consciousness and environmental consciousness in participatory development by measures of optimization of Logistics and mobility of users or citizens.\u00c3\u0082\u00c2 Its objective aims to investigate and discuss the feasibility of partnerships for the direction on main integrated community structure in university campuses with the dedication of urban mobility instruments.\u00c3\u0082\u00c2 The methodology of legal and documentary primary doctrinal analysis of the principles of participation and sustainable development demonstrates the comparative argumentation of a participatory and democratic society.\u00c3\u0082\u00c2 The hypotheses indicate that a participatory system increases people\u00c3\u00a2\u00e2\u0082\u00ac\u00e2\u0084\u00a2s consciousness and Social Environmental Commitment (SEC) and their life quality.\u00c3\u0082\u00c2 In general, the efforts of university governance involving its human capital and its environment in these actions contribute to evidence of integration and protection of the common good leading to careful outcomes with the cities in parallels. \u00c3\u0082\u00c2\u00a9 2018, Springer International Publishing AG, part of Springer Nature.",
      "authors": [
        "Almeida, P.S.",
        "Lopes, A.S.",
        "Oliveira, B.D."
      ],
      "categories": null,
      "citations": 4,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1007/978-3-319-76885-4_13",
      "keywords": [
        "Participation",
        "Sustainable university campus",
        "Environmental educational environment",
        "Sustainable cities mobility",
        "Carbon reduction",
        "University governance"
      ],
      "number_of_pages": 8,
      "pages": "197-204",
      "publication": {
        "category": "Book",
        "cite_score": 1.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "21997373",
        "publisher": "Springer Nature Switzerland AG",
        "sjr": 0.975,
        "snip": 0.965,
        "subject_areas": [
          "Environmental Science (all)",
          "Geography, Planning and Development"
        ],
        "title": "World Sustainability Series"
      },
      "publication_date": "2018-01-01",
      "selected": false,
      "title": "Sustainability in University Campuses and Environmental Education Policy: Complementary Governances Toward Consciousness Structure in Carbon Emissions Reductions",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85071565483&origin=inward"
      ]
    },
    {
      "abstract": "Objective To characterize lifetime and current rates of attention-deficit/hyperactivity disorder (ADHD) treatments among US children and adolescents with current ADHD and describe the association of these treatments with demographic and clinical factors. Study design Data are from the 2014 National Survey of the Diagnosis and Treatment of ADHD and Tourette Syndrome, a follow-back survey of parents from the 2011-2012 National Survey of Children's Health. Weighted analyses focused on receipt of ADHD treatment among children aged 4-17 years with current ADHD (n = 2495) by 4 treatment types: medication, school supports, psychosocial interventions, and alternative treatments. Results Medication and school supports were the most common treatments received, with two-thirds of children and adolescents with ADHD currently receiving each treatment. Social skills training was the most common psychosocial treatment ever received (39%), followed by parent training (31%), peer intervention (30%), and cognitive behavioral therapy (20%). Among alternative treatments, 9% were currently taking dietary supplements, and 11% had ever received neurofeedback. Most children (67%) had received at least 2 of the following: current medication treatment, current school supports, or lifetime psychosocial treatment; 7% had received none of these 3 treatment types. Conclusions A majority of school-aged children and adolescents with ADHD received medication treatment and school supports, whereas fewer received recommended psychosocial interventions. Efforts to increase access to psychosocial treatments may help close gaps in service use by groups currently less likely to receive treatment, which is important to ensure that the millions of school-aged US children diagnosed with ADHD receive quality treatment. \u00c2\u00a9 2017",
      "authors": [
        "Danielson, Melissa L",
        "Visser, Susanna N",
        "Chronis-Tuscano, Andrea",
        "DuPaul, George J"
      ],
      "categories": null,
      "citations": 68,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1016/j.jpeds.2017.08.040",
      "keywords": [
        "@UI",
        "N medication",
        "N psychosocial treatment",
        "N epidemiology",
        "#text",
        "N school services"
      ],
      "number_of_pages": null,
      "pages": "240-246.e1",
      "publication": {
        "category": "Journal",
        "cite_score": 5.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1097-6833",
        "publisher": "Mosby Inc.",
        "sjr": 1.043,
        "snip": 1.32,
        "subject_areas": [
          "Pediatrics, Perinatology and Child Health"
        ],
        "title": "The Journal of pediatrics"
      },
      "publication_date": "2017-11-10",
      "selected": false,
      "title": "A National Description of Treatment among United States Children and Adolescents with Attention-Deficit/Hyperactivity Disorder.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85033588982&origin=inward"
      ]
    },
    {
      "abstract": "Real-time fMRI neurofeedback is a feasible tool to learn the volitional regulation of brain activity. So far, most studies provide continuous feedback information that is presented upon every volume acquisition. Although this maximizes the temporal resolution of feedback information, it may be accompanied by some disadvantages. Participants can be distracted from the regulation task due to (1) the intrinsic delay of the hemodynamic response and associated feedback and (2) limited cognitive resources available to simultaneously evaluate feedback information and stay engaged with the task. Here, we systematically investigate differences between groups presented with different variants of feedback (continuous vs. intermittent) and a control group receiving no feedback on their ability to regulate amygdala activity using positive memories and feelings. In contrast to the feedback groups, no learning effect was observed in the group without any feedback presentation. The group receiving intermittent feedback exhibited better amygdala regulation performance when compared with the group receiving continuous feedback. Behavioural measurements show that these effects were reflected in differences in task engagement. Overall, we not only demonstrate that the presentation of feedback is a prerequisite to learn volitional control of amygdala activity but also that intermittent feedback is superior to continuous feedback presentation.",
      "authors": [
        "Hellrung, Lydia",
        "Dietrich, Anja",
        "Hollmann, Maurice",
        "Pleger, Burkhard",
        "Kalberlah, Christian",
        "Roggenhofer, Elisabeth",
        "Villringer, Arno",
        "Horstmann, Annette"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.neuroimage.2017.10.031",
      "keywords": [
        "N Continuous feedback",
        "D016428 Journal Article",
        "N Real-time fMRI",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Neurofeedback",
        "N Amygdala",
        "N Intermittent feedback"
      ],
      "number_of_pages": 11,
      "pages": "198-208",
      "publication": {
        "category": "Journal",
        "cite_score": 11.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1095-9572",
        "publisher": "Academic Press Inc.",
        "sjr": 2.512,
        "snip": 1.782,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Neurology"
        ],
        "title": "NeuroImage"
      },
      "publication_date": "2017-10-31",
      "selected": false,
      "title": "Intermittent compared to continuous real-time fMRI neurofeedback boosts control over amygdala activation.",
      "urls": []
    },
    {
      "abstract": "via P P P 2 2 2 In this study, we investigated the effects of dual-hemisphere transcranial direct current stimulation (dual-tDCS) of both the affected (anodal tDCS) and non-affected (cathodal tDCS) primary motor cortex, combined with peripheral neuromuscular electrical stimulation (PNMES), on the effectiveness of constraint-induced movement therapy (CIMT) as a neurorehabilitation intervention in chronic stroke. We conducted a randomized controlled trial of feasibility, with a single blind assessor, with patients recruited from three outpatient clinics. Twenty chronic stroke patients were randomly allocated to the control group, receiving conventional CIMT, or the intervention group receiving dual-tDCS combined with PNMES before CIMT. Patients in the treatment group first underwent a 20-min period of dual-tDCS, followed immediately by PNMES, and subsequent CIMT for 2\u2009h. Patients in the control group only received CIMT (with no pretreatment stimulation). All patients underwent two CIMT sessions, one in the morning and one in the afternoon, each lasting 2\u2009h, for a total of 4\u2009h of CIMT per day. Upper extremity function was assessed using the Fugl-Meyer Assessment (primary outcome), as well as the amount of use (AOU) and quality of movement (QOM) scores, obtained  the Motor Activity Log (secondary outcome). Nineteen patients completed the study, with one patient withdrawing after allocation. Compared to the control group, the treatment improvement in upper extremity function and AOU was significantly greater in the treatment than control group (change in upper extremity score, 9.20\u2009\u00b1\u20094.64 versus 4.56\u2009\u00b1\u20092.60, respectively, \u2009<\u20090.01, \u03b7\u2009=\u20090.43; change in AOU score, 1.10\u2009\u00b1\u20090.65 versus 0.62\u2009\u00b1\u20090.85, respectively, \u2009=\u20090.02, \u03b7\u2009=\u20090.52). There was no significant effect of the intervention on the QOM between the intervention and control groups (change in QOM score, 1.00\u2009\u00b1\u20090.62 versus 0.71\u2009\u00b1\u20090.72, respectively, \u2009=\u20090.07, \u03b7\u2009=\u20090.43; treatment versus control). Our findings suggest a novel pretreatment stimulation strategy based on dual-tDCS and PNMES may enhance the therapeutic benefit of CIMT.",
      "authors": [
        "Takebayashi, Takashi",
        "Takahashi, Kayoko",
        "Moriwaki, Misa",
        "Sakamoto, Tomosaburo",
        "Domen, Kazuhisa"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3389/fneur.2017.00568",
      "keywords": [
        "@UI",
        "N constraint-induced movement therapy",
        "N upper extremity",
        "N stroke",
        "N neuromuscular stimulation",
        "N transcranial direct current stimulation",
        "#text",
        "N rehabilitation"
      ],
      "number_of_pages": null,
      "pages": "568",
      "publication": {
        "category": "Journal",
        "cite_score": 4.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1664-2295",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.978,
        "snip": 1.151,
        "subject_areas": [
          "Neurology (clinical)",
          "Neurology"
        ],
        "title": "Frontiers in neurology"
      },
      "publication_date": "2017-10-30",
      "selected": false,
      "title": "Improvement of Upper Extremity Deficit after Constraint-Induced Movement Therapy Combined with and without Preconditioning Stimulation Using Dual-hemisphere Transcranial Direct Current Stimulation and Peripheral Neuromuscular Stimulation in Chronic Stroke Patients: A Pilot Randomized Controlled Trial.",
      "urls": []
    },
    {
      "abstract": "BACKGROUND BACKGROUND Deep brain stimulation (DBS) indications include movement disorders, psychiatric affections, or epilepsy in which patients risk social isolation heightened by abnormal motions or behavioral patterns. Further stigmatization after DBS surgery from head shaving, visible scarring, or disfigurement from bulky lead insertion points should be avoided.\nOBJECTIVE OBJECTIVE We present a cosmetically optimized, adapted submammarian approach for DBS neurostimulator implantation that leaves the d\u00e9colletage untouched.\nMETHODS METHODS Over 24 months, 61 patients suffering from Parkinson disease, dystonia, or tremor underwent DBS surgery. The modified, submammarian approach was compared with the conventional infraclavicular approach regarding clinical outcome, complications, and limitations over a 5-year follow-up.\nRESULTS RESULTS Neurostimulators were implanted in a paraumbilical (n\u00a0= 20) or infraclavicular position (n\u00a0= 41; Parkinson disease, n\u00a0= 27; dystonia, n\u00a0= 9; tremor, n\u00a0= 5), the latter using a standard (n\u00a0= 16), modified juxta-axillary (n\u00a0= 6), or submammarian approach (n\u00a0= 19; 18 women, 1 man with significant gynecomastia). After 12 months, there was no significant difference in the infection rate and one event of rebleeding in each group. Overall, operation time was longer (+20 minutes) for the submammarian versus standard, infraclavicular approach, but acceptable. Neurostimulator replacement was, necessary within 5 years due to advanced battery discharge (n\u00a0= 32). Battery replacement was easily achieved using the submammarian approach (n\u00a0= 14), again with increased surgical time (+20 minutes), and iatrogenic damage to extensions was avoidable.\nCONCLUSIONS CONCLUSIONS A submammarian approach might be an alternative for infraclavicular implantation of DBS neurostimulators, particularly in female patients in the context of cosmetically optimized surgery. Patients' self-perception and self-esteem may be strengthened, potentially enabling them to better cope with disease.",
      "authors": [
        "Stroop, Ralf",
        "Holms, Frank",
        "Nakamura, Makoto",
        "Lehrke, Ralph"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.wneu.2017.10.057",
      "keywords": [
        "N Deep brain stimulation",
        "@UI",
        "N Aesthetic surgery",
        "N Submammarian approach",
        "N Positive self-perception",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "e699-e706",
      "publication": {
        "category": "Journal",
        "cite_score": 3.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1878-8769",
        "publisher": "Elsevier Inc.",
        "sjr": 0.591,
        "snip": 1.032,
        "subject_areas": [
          "Neurology (clinical)",
          "Surgery"
        ],
        "title": "World neurosurgery"
      },
      "publication_date": "2017-10-20",
      "selected": false,
      "title": "A Submammarian Approach for Cosmetically Improved Implantation of Deep Brain Stimulation Generators.",
      "urls": []
    },
    {
      "abstract": "Normative judgment is a key capacity for human social norm compliance. Previous studies have revealed that the right lateral prefrontal cortex (rLPFC) is closely related to social norm compliance and that it has proven stimulation effects on behavior in voluntary and sanction-induced norm compliance, but not normative judgments. Nearly all these studies have been based on sanction-induced coordination cooperation, and a number of them have found that rLPFC has no effect on normative judgment with transcranial direct current stimulation (tDCS). However, no research study exists regarding the effects of the normative judgment in voluntary cooperation. In this study, we used a linear asymmetric public good game to investigate the role of normative judgment in voluntary cooperation with tDCS on rLPFC. Participants were engaged in anonymous social interactions and made decisions with real financial consequences after being randomly assigned to receive either anodal, cathodal, or sham stimulation of 15 min. Results suggest that compared with the sham group, anodal/cathodal tDCS influenced the behavior and normative judgment of participants in opposite directions. These outcomes provide a neural evidence for the rLPFC mechanism on normative judgment in voluntary cooperation. \u00c2\u00a9 2017 Elsevier B.V.",
      "authors": [
        "Liu, Xiaoli",
        "Li, Jianbiao",
        "Wang, Guangrong",
        "Yin, Xile",
        "Li, Shuaiqi",
        "Fu, Xiaogai"
      ],
      "categories": null,
      "citations": 2,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1016/j.neulet.2017.10.020",
      "keywords": [
        "N Normative judgments",
        "D016428 Journal Article",
        "N tDCS",
        "D016454 Review",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Voluntary cooperation",
        "N rLPFC"
      ],
      "number_of_pages": null,
      "pages": "133164",
      "publication": {
        "category": "Journal",
        "cite_score": 5.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1872-7972",
        "publisher": "Elsevier Ireland Ltd",
        "sjr": 0.802,
        "snip": 0.777,
        "subject_areas": [
          "Neuroscience (all)"
        ],
        "title": "Neuroscience letters"
      },
      "publication_date": "2017-10-13",
      "selected": false,
      "title": "Transcranial direct current stimulation of the rLPFC shifts normative judgments in voluntary cooperation.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85031404182&origin=inward"
      ]
    },
    {
      "abstract": "Sanction is used by almost all known human societies to enforce fairness norm in resource distribution. Previous studies have consistently shown that the lateral prefrontal cortex (lPFC) and the adjacent orbitofrontal cortex (lOFC) play a causal role in mediating the effect of sanction threat on norm compliance. However, most of these studies were conducted in gain domain in which resources are distributed. Little is known about the mechanisms underlying norm compliance in loss domain in which individual sacrifices are needed. Here we employed a modified version of dictator game (DG) and high-definition transcranial direct current stimulation (HD-tDCS) to investigate to what extent lPFC/lOFC is involved in norm compliance (with and without sanction threat) in both gain- and loss-sharing contexts. Participants allocated a fixed total amount of monetary gain or loss between themselves and an anonymous partner in multiple rounds of the game. A computer program randomly decided whether a given round involved sanction threat for the participants. Results showed that disruption of the right lPFC/lOFC by tDCS increased the voluntary norm compliance in the gain domain, but not in the loss domain; tDCS on lPFC/lOFC had no effect on compliance under sanction threat in either the gain or loss domain. Our findings reveal a context-dependent nature of norm compliance and differential roles of lPFC/lOFC in norm compliance in gain and loss domains. \u00c2\u00a9 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd",
      "authors": [
        "Yin, Yunlu",
        "Yu, Hongbo",
        "Su, Zhongbin",
        "Zhang, Yuan",
        "Zhou, Xiaolin"
      ],
      "categories": null,
      "citations": 13,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1111/ejn.13653",
      "keywords": [
        "N sanction threat",
        "#text",
        "N norm compliance",
        "N lateral prefrontal and orbitofrontal cortex (LPFC/LOFC)",
        "N HD-tDCS",
        "N gain-loss domain",
        "@UI"
      ],
      "number_of_pages": 8,
      "pages": "2088-2095",
      "publication": {
        "category": "Journal",
        "cite_score": 6.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1460-9568",
        "publisher": "Wiley-Blackwell Publishing Ltd",
        "sjr": 1.044,
        "snip": 0.891,
        "subject_areas": [
          "Neuroscience (all)"
        ],
        "title": "The European journal of neuroscience"
      },
      "publication_date": "2017-08-21",
      "selected": false,
      "title": "Lateral prefrontal/orbitofrontal cortex has different roles in norm compliance in gain and loss domains: a transcranial direct current stimulation study.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85028696248&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND BACKGROUND Attention deficit hyperactivity disorder (ADHD) is one of the most commonly diagnosed psychiatric disorders in childhood. A wide variety of treatments have been used for the management of ADHD. We aimed to compare the efficacy and safety of pharmacological, psychological and complementary and alternative medicine interventions for the treatment of ADHD in children and adolescents.\nMETHODS AND FINDINGS RESULTS We performed a systematic review with network meta-analyses. Randomised controlled trials (\u2265 3 weeks follow-up) were identified from published and unpublished sources through searches in PubMed and the Cochrane Library (up to April 7, 2016). Interventions of interest were pharmacological (stimulants, non-stimulants, antidepressants, antipsychotics, and other unlicensed drugs), psychological (behavioural, cognitive training and neurofeedback) and complementary and alternative medicine (dietary therapy, fatty acids, amino acids, minerals, herbal therapy, homeopathy, and physical activity). The primary outcomes were efficacy (treatment response) and acceptability (all-cause discontinuation). Secondary outcomes included discontinuation due to adverse events (tolerability), as well as serious adverse events and specific adverse events. Random-effects Bayesian network meta-analyses were conducted to obtain estimates as odds ratios (ORs) with 95% credibility intervals. We analysed interventions by class and individually. 190 randomised trials (52 different interventions grouped in 32 therapeutic classes) that enrolled 26114 participants with ADHD were included in complex networks. At the class level, behavioural therapy (alone or in combination with stimulants), stimulants, and non-stimulant seemed significantly more efficacious than placebo. Behavioural therapy in combination with stimulants seemed superior to stimulants or non-stimulants. Stimulants seemed superior to behavioural therapy, cognitive training and non-stimulants. Behavioural therapy, stimulants and their combination showed the best profile of acceptability. Stimulants and non-stimulants seemed well tolerated. Among medications, methylphenidate, amphetamine, atomoxetine, guanfacine and clonidine seemed significantly more efficacious than placebo. Methylphenidate and amphetamine seemed more efficacious than atomoxetine and guanfacine. Methylphenidate and clonidine seemed better accepted than placebo and atomoxetine. Most of the efficacious pharmacological treatments were associated with harms (anorexia, weight loss and insomnia), but an increased risk of serious adverse events was not observed. There is lack of evidence for cognitive training, neurofeedback, antidepressants, antipsychotics, dietary therapy, fatty acids, and other complementary and alternative medicine. Overall findings were limited by the clinical and methodological heterogeneity, small sample sizes of trials, short-term follow-up, and the absence of high-quality evidence; consequently, results should be interpreted with caution.\nCONCLUSIONS CONCLUSIONS Clinical differences may exist between the pharmacological and non-pharmacological treatment used for the management of ADHD. Uncertainties about therapies and the balance between benefits, costs and potential harms should be considered before starting treatment. There is an urgent need for high-quality randomised trials of the multiple treatments for ADHD in children and adolescents. PROSPERO, number CRD42014015008.",
      "authors": [
        "Catal\u00e1-L\u00f3pez, Ferr\u00e1n",
        "Hutton, Brian",
        "N\u00fa\u00f1ez-Beltr\u00e1n, Amparo",
        "Page, Matthew J",
        "Ridao, Manuel",
        "Mac\u00edas Saint-Gerons, Diego",
        "Catal\u00e1, Miguel A",
        "Tabar\u00e9s-Seisdedos, Rafael",
        "Moher, David"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1371/journal.pone.0180355",
      "keywords": [],
      "number_of_pages": null,
      "pages": "e0180355",
      "publication": {
        "category": "Journal",
        "cite_score": 6.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1932-6203",
        "publisher": "Public Library of Science",
        "sjr": 0.885,
        "snip": 1.253,
        "subject_areas": [
          "Multidisciplinary"
        ],
        "title": "PloS one"
      },
      "publication_date": "2017-07-12",
      "selected": false,
      "title": "The pharmacological and non-pharmacological treatment of attention deficit hyperactivity disorder in children and adolescents: A systematic review with network meta-analyses of randomised trials.",
      "urls": []
    },
    {
      "abstract": "Objective: The objective of this study was to evaluate the feasibility of using paired-associative stimulation (PAS) to study excitatory and inhibitory plasticity in adolescents while examining variables that may moderate plasticity (such as sex and environment). Methods: We recruited 34 healthy adolescents (aged 13\u00e2\u0080\u009319, 13 males, 21 females). To evaluate excitatory plasticity, we compared mean motor-evoked potentials (MEPs) elicited by single-pulse transcranial magnetic stimulation (TMS) before and after PAS at 0, 15, and 30 min. To evaluate inhibitory plasticity, we evaluated the cortical silent period (CSP) elicited by single-pulse TMS in the contracted hand before and after PAS at 0, 15, and 30 min. Results: All participants completed PAS procedures. No adverse events occurred. PAS was well tolerated. PAS-induced significant increases in the ratio of post-PAS MEP to pre-PAS MEP amplitudes (p < 0.01) at all post-PAS intervals. Neither socioeconomic status nor sex was associated with post-PAS MEP changes. PAS induced significant CSP lengthening in males but not females. Conclusion: PAS is a feasible, safe, and well-tolerated index of adolescent motor cortical plasticity. Gender may influence PAS-induced changes in cortical inhibition. PAS is safe and well tolerated by healthy adolescents and may be a novel tool with which to study adolescent neuroplasticity. Copyright \u00c2\u00a9 2017 Lee, Croarkin, Ameis, Sun, Blumberger, Rajji and Daskalakis.",
      "authors": [
        "Lee, J.C.",
        "Croarkin, P.E.",
        "Ameis, S.H.",
        "Sun, Y.",
        "Blumberger, D.M.",
        "Rajji, T.K.",
        "Daskalakis, Z.J."
      ],
      "categories": null,
      "citations": 7,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3389/fpsyt.2017.00095",
      "keywords": [
        "motor cortical plasticity",
        "motor-evoked potentials",
        "developmental neuroplasticity",
        "cortical silent period",
        "adolescent psychiatry",
        "paired-associative stimulation"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Frontiers in Psychiatry"
      },
      "publication_date": "2017-05-29",
      "selected": false,
      "title": "Paired-Associative Stimulation-Induced Long-term Potentiation-Like Motor Cortex Plasticity in Healthy Adolescents",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85059350108&origin=inward"
      ]
    },
    {
      "abstract": "Neurofeedback is widely applied as non-pharmacological intervention aimed at reducing symptoms of ADHD, even though efficacy has not been unequivocally established. Neuronal changes during the neurofeedback intervention that resemble learning can provide crucial evidence for the feasibility and specificity of this intervention. A total of 38 children (aged between 7 and 13\u00c2 years) with a DSM-IV-TR diagnosis of ADHD, completed on average 29 sessions of theta (4\u00e2\u0080\u00938\u00c2 Hz)/beta (13\u00e2\u0080\u009320\u00c2 Hz) neurofeedback training. Dependent variables included training-related measures as well as theta and beta power during baseline and training runs for each session. Learning effects were analyzed both within and between sessions. To further specify findings, individual learning curves were explored and correlated with behavioral changes in ADHD symptoms. Over the course of the training, there was a linear increase in participants\u00e2\u0080\u0099 mean training level, highest obtained training level and the number of earned credits (range b\u00c2 =\u00c2 0.059, \u00e2\u0088\u00920.750, p\u00c2 <\u00c2 0.001). Theta remained unchanged over the course of the training, while beta activity increased linearly within training sessions (b\u00c2 =\u00c2 0.004, 95% CI\u00c2 =\u00c2 [0.0013\u00e2\u0080\u00930.0067], p\u00c2 =\u00c2 0.005) and over the course of the intervention (b\u00c2 =\u00c2 0.0052, 95% CI\u00c2 =\u00c2 [0.0039\u00e2\u0080\u00930.0065], p\u00c2 <\u00c2 0.001). In contrast to the group analyses, significant individual learning curves were found for both\u00c2 theta and beta over the course of the intervention in 39 and 53%, respectively. Individual learning curves were not significantly correlated with behavioral changes. This study shows that children with ADHD can gain control over EEG states during neurofeedback, although a lack of behavioral correlates may indicate insufficient transfer to daily functioning, or to confounding reinforcement of electromyographic activity. Clinical Trials Registration: This trial is registered at the US National Institutes of Health (ClinicalTrials.gov, ref. no: NCT01363544); https://clinicaltrials.gov/show/NCT01363544. \u00c2\u00a9 2016, The Author(s).",
      "authors": [
        "Janssen, T.W.P.",
        "Bink, M.",
        "Weeda, W.D.",
        "Gelad\u00c3\u00a9, K.",
        "van Mourik, R.",
        "Maras, A.",
        "Oosterlaan, J."
      ],
      "categories": null,
      "citations": 32,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1007/s00787-016-0920-8",
      "keywords": [
        "Learning curves",
        "EEG",
        "Neurofeedback",
        "ADHD",
        "Paediatric",
        "Theta/beta-training"
      ],
      "number_of_pages": 10,
      "pages": "573-582",
      "publication": {
        "category": "Journal",
        "cite_score": 10.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "10188827",
        "publisher": "D. Steinkopff-Verlag",
        "sjr": 1.799,
        "snip": 2.111,
        "subject_areas": [
          "Developmental and Educational Psychology",
          "Psychiatry and Mental Health",
          "Pediatrics, Perinatology and Child Health"
        ],
        "title": "European Child and Adolescent Psychiatry"
      },
      "publication_date": "2017-05-01",
      "selected": false,
      "title": "Learning curves of theta/beta neurofeedback in children with ADHD",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84995755288&origin=inward"
      ]
    },
    {
      "abstract": "OBJECTIVE Dysfunction of distributed neural networks underlies many brain disorders. The development of neuromodulation therapies depends on a better understanding of these networks. Invasive human brain recordings have a favorable temporal and spatial resolution for the analysis of network phenomena but have generally been limited to acute intraoperative recording or short-term recording through temporarily externalized leads. Here, the authors describe their initial experience with an investigational, first-generation, totally implantable, bidirectional neural interface that allows both continuous therapeutic stimulation and recording of field potentials at multiple sites in a neural network. METHODS Under a physician-sponsored US Food and Drug Administration investigational device exemption, 5 patients with Parkinson's disease were implanted with the Activa PC+S system (Medtronic Inc.). The device was attached to a quadripolar lead placed in the subdural space over motor cortex, for electrocorticography potential recordings, and to a quadripolar lead in the subthalamic nucleus (STN), for both therapeutic stimulation and recording of local field potentials. Recordings from the brain of each patient were performed at multiple time points over a 1-year period. RESULTS There were no serious surgical complications or interruptions in deep brain stimulation therapy. Signals in both the cortex and the STN were relatively stable over time, despite a gradual increase in electrode impedance. Canonical movement-related changes in specific frequency bands in the motor cortex were identified in most but not all recordings. CONCLUSIONS The acquisition of chronic multisite field potentials in humans is feasible. The device performance characteristics described here may inform the design of the next generation of totally implantable neural interfaces. This research tool provides a platform for translating discoveries in brain network dynamics to improved neurostimulation paradigms. Clinical trial registration no.: NCT01934296 (clinicaltrials.gov).",
      "authors": [
        "Swann, Nicole C",
        "de Hemptinne, Coralie",
        "Miocinovic, Svjetlana",
        "Qasim, Salman",
        "Ostrem, Jill L",
        "Galifianakis, Nicholas B",
        "Luciano, Marta San",
        "Wang, Sarah S",
        "Ziman, Nathan",
        "Taylor, Robin",
        "Starr, Philip A"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3171/2016.11.JNS161162",
      "keywords": [
        "N Parkinson's disease",
        "N DBS",
        "N DBS = deep brain stimulation",
        "N EKG = electrocardiogram",
        "N STN = subthalamic nucleus",
        "N FDA = Food and Drug Administration",
        "N PSD = power spectral density",
        "N brain-machine interface",
        "N ECoG = electrocorticography",
        "N PD = Parkinson's disease",
        "D052061 Research Support, N.I.H., Extramural",
        "N PD",
        "N motor cortex",
        "N basal ganglia",
        "N deep brain stimulation",
        "D016428 Journal Article",
        "N UPDRS = Unified Parkinson's Disease Rating Scale",
        "N electrophysiology",
        "D013485 Research Support, Non-U.S. Gov't",
        "N RMS = root mean square",
        "N LFP = local field potential",
        "N functional neurosurgery",
        "N IPG = implanted pulse generator"
      ],
      "number_of_pages": 12,
      "pages": "605-616",
      "publication": {
        "category": "Journal",
        "cite_score": 8.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1933-0693",
        "publisher": "American Association of Neurological Surgeons",
        "sjr": 1.138,
        "snip": 1.896,
        "subject_areas": [
          "Neurology (clinical)",
          "Surgery"
        ],
        "title": "Journal of neurosurgery"
      },
      "publication_date": "2017-04-14",
      "selected": false,
      "title": "Chronic multisite brain recordings from a totally implantable bidirectional neural interface: experience in 5 patients with Parkinson's disease.",
      "urls": []
    },
    {
      "abstract": "Surface structuring of titanium-based implants is known to modulate the behavior of adherent cells, but the influence of different nanotopographies is poorly understood. The aim is to investigate preosteoblast proliferation, adhesion, morphology, and migration on surfaces with similar surface chemistry but distinct nanotopographical features. Sonochemical treatment and anodic oxidation are employed to fabricate disordered, mesoporous titania (TMS) and ordered titania nanotubular (TNT) topographies on titanium, respectively. Morphological evaluation reveals that cells are polygonal and well-spread on TMS, but display an elongated, fibroblast-like morphology on TNT surfaces, while they are much flatter on glass. Both nanostructured surfaces impair cell adhesion, but TMS is more favorable for cell growth due to its support of cell attachment and spreading in contrast to TNT. A quantitative wound healing assay in combination with live-cell imaging reveals that cell migration on TMS surfaces has a more collective character than on other surfaces, probably due to a closer proximity between neighboring migrating cells on TMS. The results indicate distinctly different cell adhesion and migration on ordered and disordered titania nanotopographies, providing important information that can be used in optimizing titanium-based scaffold design to foster bone tissue growth and repair while allowing for the encapsulation of drugs into porous titania layer.",
      "authors": [
        "Zhukova, Yulia",
        "Hiepen, Christian",
        "Knaus, Petra",
        "Osterland, Marc",
        "Prohaska, Steffen",
        "Dunlop, John W C",
        "Fratzl, Peter",
        "Skorb, Ekaterina V"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1002/adhm.201601244",
      "keywords": [
        "N interface",
        "N cell adhesion",
        "#text",
        "N titanium",
        "N migration",
        "N nanotopography",
        "@UI"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": 15.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2192-2659",
        "publisher": "John Wiley and Sons Ltd",
        "sjr": 2.114,
        "snip": 1.452,
        "subject_areas": [
          "Biomaterials",
          "Pharmaceutical Science",
          "Biomedical Engineering"
        ],
        "title": "Advanced healthcare materials"
      },
      "publication_date": "2017-03-30",
      "selected": false,
      "title": "The Role of Titanium Surface Nanostructuring on Preosteoblast Morphology, Adhesion, and Migration.",
      "urls": []
    },
    {
      "abstract": "Societies are characterized by a shared system of social norms, which promotes cooperation among people. However, following social norms often means going against self-interest\u00e2\u0080\u0094imagine, for example, being required to choose whether or not to get richer from an unfair deal; ignoring social norms, on the other hand, may elicit disruptive antisocial behaviors that damage human relationships. Therefore, this type of value-based decisions is particularly tough and requires a complex trade-off between self- and other-regarding motivations. The advancement in cognitive neuroscience has shed light on the mechanisms underlying social norm compliance, describing the interplay between the emotional, reward, and self-control systems in shaping social norm preference (Fehr and Camerer, Evolution and Human Behavior 25(2), 63\u00e2\u0080\u009387, 2007). The modulation of these systems, in particular self-control areas like dorsolateral prefrontal cortex (DLPFC), through TMS and tDCS has proven to be effective in modifying people\u00e2\u0080\u0099s behavior in socio-economic contexts (Knoch et al., Science 314(5800), 829\u00e2\u0080\u0093832, 2006; Knoch et al., Cerebral Cortex 18(9), 1987\u00e2\u0080\u00931990, 2008; Ruff et al., Science 342(6157), 482\u00e2\u0080\u0093484, 2013). The scope of the current paper is to discuss the potential benefits of the enhancement of social norm compliance in the context of therapeutic interventions, along with the issues of methodological, theoretical, and moral nature that may arise when considering the very definition of social norm: indeed, the benchmark for deciding what is right and what is wrong is not always easy to determine in the social context, and thus, the implications of proposing interventions aimed at modulating social norm compliance, although definitely promising, should also be considered carefully. \u00c2\u00a9 2017, Springer International Publishing.",
      "authors": [
        "Civai, C.",
        "Ma, I."
      ],
      "categories": null,
      "citations": 7,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1007/s41465-017-0009-4",
      "keywords": [
        "Neuromodulation",
        "Therapeutic intervention",
        "Social norms"
      ],
      "number_of_pages": 5,
      "pages": "26-30",
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "25093290",
        "publisher": "Springer Nature",
        "sjr": 1.799,
        "snip": 2.111,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Experimental and Cognitive Psychology",
          "Behavioral Neuroscience",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Journal of Cognitive Enhancement"
      },
      "publication_date": "2017-03-01",
      "selected": false,
      "title": "The Enhancement of Social Norm Compliance: Prospects and Caveats",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85059207864&origin=inward"
      ]
    },
    {
      "abstract": "Promising results in adult neurologic and psychiatric disorders are driving active research into transcranial brain stimulation techniques, particularly transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), in childhood and adolescent syndromes. TMS has realistic utility as an experimental tool tested in a range of pediatric neuropathologies such as perinatal stroke, depression, Tourette syndrome, and autism spectrum disorder (ASD). tDCS has also been tested as a treatment for a number of pediatric neurologic conditions, including ASD, attention-deficit/hyperactivity disorder, epilepsy, and cerebral palsy. Here, we complement recent reviews with an update of published TMS and tDCS results in children, and discuss developmental neuroscience considerations that should inform pediatric transcranial stimulation.",
      "authors": [
        "Hameed, Mustafa Q",
        "Dhamne, Sameer C",
        "Gersner, Roman",
        "Kaye, Harper L",
        "Oberman, Lindsay M",
        "Pascual-Leone, Alvaro",
        "Rotenberg, Alexander"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1007/s11910-017-0719-0",
      "keywords": [
        "N Transcranial stimulation in children",
        "N GABA",
        "D016428 Journal Article",
        "N TMS",
        "N tDCS",
        "D016454 Review",
        "N Cortical excitability",
        "N Cortical inhibition"
      ],
      "number_of_pages": null,
      "pages": "11",
      "publication": {
        "category": "Journal",
        "cite_score": 9.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1534-6293",
        "publisher": "Current Medicine Group",
        "sjr": 1.506,
        "snip": 2.075,
        "subject_areas": [
          "Neurology (clinical)",
          "Neuroscience (all)"
        ],
        "title": "Current neurology and neuroscience reports"
      },
      "publication_date": "2017-02-01",
      "selected": false,
      "title": "Transcranial Magnetic and Direct Current Stimulation in Children.",
      "urls": []
    },
    {
      "abstract": "The phenomenon of loss aversion (the tendency for losses to have a greater impact than comparable gains) has long been observed in daily life. Neurocognitive studies and brain imaging studies have shed light on the correlation between the phenomenon of loss aversion and the brain region of the prefrontal cortex. Recent brain stimulation studies using bilateral transcranial magnetic stimulation or transcranial direct current stimulation (tDCS) have obtained various results showing the causal relationship between brain regions and decision making. With the goal of studying whether unilateral stimulation can change participants' risky decision making in the frames of gains and losses, we applied different polarities of tDCS over the regions of the right or left prefrontal cortex. We also designed a risk measurement table (Multiple Price List) to reflect the participants' attitudes toward risky decision making via the crossover point including the frames of gains and losses. The results of our experiment indicated that the participants tended to be more risk averse in the gain frame after receiving left anodal tDCS and more risk seeking in the loss frame after receiving right cathodal tDCS, which was consistent with the hypothesis that the process of risky decision making was correlated with the interaction of multiple systems in the brain. Our conclusion revealed an asymmetric effect of right/left DLPFC when the participants faced gains and losses, which partially provided the neural evidence and a feasible paradigm to help better understand risky decision making and loss aversion. The current study can not only expand the traditional understanding of the behavioral preferences of humans in economics but also accommodate empirical observations of behavioral economists on the preferences of humans.",
      "authors": [
        "Huang, Daqiang",
        "Chen, Shu",
        "Wang, Siqi",
        "Shi, Jinchuan",
        "Ye, Hang",
        "Luo, Jun",
        "Zheng, Haoli"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3389/fpsyg.2017.00038",
      "keywords": [
        "@UI",
        "N risk preference",
        "N loss aversion",
        "N dorsolateral prefrontal cortex",
        "N transcranial direct current stimulation",
        "#text",
        "N asymmetric effect"
      ],
      "number_of_pages": null,
      "pages": "38",
      "publication": {
        "category": "Journal",
        "cite_score": 4.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1664-1078",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.891,
        "snip": 1.422,
        "subject_areas": [
          "Psychology (all)"
        ],
        "title": "Frontiers in psychology"
      },
      "publication_date": "2017-01-24",
      "selected": false,
      "title": "Activation of the DLPFC Reveals an Asymmetric Effect in Risky Decision Making: Evidence from a tDCS Study.",
      "urls": []
    },
    {
      "abstract": "Transcranial direct current stimulation (tDCS) is a promising technology to enhance cognitive and physical performance. One of the major areas of interest is the enhancement of memory function in healthy individuals. The early arrival of tDCS on the market for lifestyle uses and cognitive enhancement purposes lead to the voicing of some important ethical concerns, especially because, to date, there are no official guidelines or evaluation procedures to tackle these issues. The aim of this article is to review ethical issues related to uses of tDCS for memory enhancement found in the ethics and neuroscience literature and to evaluate how realistic and scientifically well-founded these concerns are? In order to evaluate how plausible or speculative each issue is, we applied the methodological framework described by Racine et al. (2014) for \u00e2\u0080\u009cinformed and reflective\u00e2\u0080\u009d speculation in bioethics. This framework could be succinctly presented as requiring: (1) the explicit acknowledgment of factual assumptions and identification of the value attributed to them; (2) the validation of these assumptions with interdisciplinary literature; and (3) the adoption of a broad perspective to support more comprehensive reflection on normative issues. We identified four major considerations associated with the development of tDCS for memory enhancement: safety, autonomy, justice and authenticity. In order to assess the seriousness and likelihood of harm related to each of these concerns, we analyzed the assumptions underlying the ethical issues, and the level of evidence for each of them. We identified seven distinct assumptions: prevalence, social acceptance, efficacy, ideological stance (bioconservative vs. libertarian), potential for misuse, long term side effects, and the delivery of complete and clear information. We conclude that ethical discussion about memory enhancement via tDCS sometimes involves undue speculation, and closer attention to scientific and social facts would bring a more nuanced analysis. At this time, the most realistic concerns are related to safety and violation of users\u00e2\u0080\u0099 autonomy by a breach of informed consent, as potential immediate and long-term health risks to private users remain unknown or not well defined. Clear and complete information about these risks must be provided to research participants and consumers of tDCS products or related services. Broader public education initiatives and warnings would also be worthwhile to reach those who are constructing their own tDCS devices. \u00c2\u00a9 2017 Voarino, Dubljevi\u00c4\u0087 and Racine.",
      "authors": [
        "Voarino, Nathalie",
        "Dubljevi\u0107, Veljko",
        "Racine, Eric"
      ],
      "categories": null,
      "citations": 24,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.3389/fnhum.2016.00678",
      "keywords": [
        "N brain stimulation",
        "@UI",
        "N tDCS",
        "N cognitive enhancement",
        "N ethics",
        "N memory enhancement",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "678",
      "publication": {
        "category": "Journal",
        "cite_score": 4.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1662-5161",
        "publisher": "Frontiers Media S.A.",
        "sjr": 0.787,
        "snip": 1.033,
        "subject_areas": [
          "Psychiatry and Mental Health",
          "Neurology",
          "Biological Psychiatry",
          "Neuropsychology and Physiological Psychology",
          "Behavioral Neuroscience"
        ],
        "title": "Frontiers in human neuroscience"
      },
      "publication_date": "2017-01-11",
      "selected": false,
      "title": "tDCS for Memory Enhancement: Analysis of the Speculative Aspects of Ethical Issues.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85010903542&origin=inward"
      ]
    },
    {
      "abstract": "Purpose: The purpose of this paper is to present a theory that applies Miller et al.\u00e2\u0080\u0099s (1960) Test-Operate-Test-Exit (TOTE) concept to the psychophysiology involved in electroencephalographic (EEG) biofeedback (BFB). Design/methodology/approach: Six components are presented, namely, the teleological brain, attractors as the \u00e2\u0080\u009ctest\u00e2\u0080\u009d in TOTEs, EEG production, positive and negative feedback, synaptogenesis and designated actor, and then integrated into a theoretical structure. Comparisons with the previous conceptualizations are discussed, and finally, suggestions for practical application and needed research are offered. Findings: Previous theories neglected significant variables and promoted unverified conceptualizations. These issues are redressed with a psychophysiological, cybernetic theory. Research limitations/implications: The pursuit of substantive research needed to verify the theory would improve the scientific foundations for EEG BFB. Practical implications: This theory shifts the designated actor in BFB to the participant\u00e2\u0080\u0099s brain, away from the BFB provider. EEG BFB is thus viewed as a means for neuronominalization driven by the brain\u00e2\u0080\u0099s attractor systems instead of as an intrusive intervention. Social implications: The theory proposes a much more participant-centric process than previous modes, which also promotes self-determination. The research validation needed for the theory could produce wider EEG BFB acceptance and application. Originality/value: The theory is a complete departure from previous conceptualizations. It is the first instance of TOTE application to psychophysiological processes, and it is the first fully cybernetic conceptualization of EEG BFB. \u00c2\u00a9 2017, \u00c2\u00a9 Emerald Publishing Limited.",
      "authors": [
        "Patterson, K.E."
      ],
      "categories": null,
      "citations": 1,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1108/K-11-2016-0339",
      "keywords": [
        "Theory",
        "Biofeedback",
        "EEG",
        "Neurofeedback",
        "Biocybernetics"
      ],
      "number_of_pages": 18,
      "pages": "638-655",
      "publication": {
        "category": "Journal",
        "cite_score": 4.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "0368492X",
        "publisher": "Emerald Group Publishing Ltd.",
        "sjr": 0.44,
        "snip": 0.839,
        "subject_areas": [
          "Social Sciences (miscellaneous)",
          "Control and Systems Engineering",
          "Theoretical Computer Science",
          "Computer Science (miscellaneous)",
          "Engineering (miscellaneous)"
        ],
        "title": "Kybernetes"
      },
      "publication_date": "2017-01-01",
      "selected": false,
      "title": "A cybernetic theory for EEG biofeedback",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85016743412&origin=inward"
      ]
    },
    {
      "abstract": "Bladder and bowel dysfunction (BBD) describes a spectrum of lower urinary symptoms (LUTS) accompanied by fecal elimination issues that manifest primarily by constipation and/or encopresis. This increasingly common entity is a potential cause of significant physical and psychosocial burden for children and families. BBD is commonly associated with vesicoureteral reflux (VUR) and recurrent urinary tract infections (UTIs), which at its extreme may lead to renal scarring and kidney failure. Additionally, BBD is frequently seen in children diagnosed with behavioural and neuropsychiatric disorders such as attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Patients with concomitant BBD and neuropsychiatric disorders have less favourable treatment outcomes. Early diagnosis and treatment of BBD are critical to avoid secondary comorbidities that can adversely impact children's kidney and bladder function, and psychosocial well-being. The majority of patients will improve with urotherapy, adequate fluid intake, and constipation treatment. Pharmacological treatment must only be considered if no improvement occurs after intensive adherence to at least six months of urotherapy \u00c2\u00b1 biofeedback and constipation treatment. Anticholinergics remain the mainstay of medical treatment. Selective alpha-blockers appear to be effective for improving bladder emptying in children with non-neurogenic detrusor overactivity (DO), incontinence, recurrent UTIs, and increased post-void residual (PVR) urine volumes. Alpha-1 blockers can also be used in combination with anticholinergics when overactive bladder (OAB) coexists with functional bladder outlet obstruction. Minimally invasive treatment with onabotulinumtoxinA bladder injections, and recently neurostimulation, are promising alternatives for the management of BBD refractory to behavioural and pharmacological treatment. In this review, we discuss clinical presentation, diagnostic approach, and indications for behavioural, pharmacological, and surgical treatment of BBD in children based on a thorough literature review. Expert opinion will be used when scientific evidence is unavailable. \u00c2\u00a9 2017 Canadian Urological Association.",
      "authors": [
        "Santos, Joana Dos",
        "Lopes, Roberto I",
        "Koyle, Martin A"
      ],
      "categories": null,
      "citations": 109,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.5489/cuaj.4411",
      "keywords": [],
      "number_of_pages": null,
      "pages": "S64-S72",
      "publication": {
        "category": "Journal",
        "cite_score": 2.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1911-6470",
        "publisher": "Canadian Medical Association",
        "sjr": 0.515,
        "snip": 0.715,
        "subject_areas": [
          "Urology"
        ],
        "title": "Canadian Urological Association journal = Journal de l'Association des urologues du Canada"
      },
      "publication_date": "2017-01-01",
      "selected": false,
      "title": "Bladder and bowel dysfunction in children: An update on the diagnosis and treatment of a common, but underdiagnosed pediatric problem.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85016230038&origin=inward"
      ]
    },
    {
      "abstract": "OBJECTIVE The purpose of this study was to report outcomes of epilepsy surgery in 56 consecutive patients with autism spectrum disorder. METHODS Medical records of 56 consecutive patients with autism who underwent epilepsy surgery were reviewed with regard to clinical characteristics, surgical management, postoperative seizure control, and behavioral changes. RESULTS Of the 56 patients with autism, 39 were male, 45 were severely autistic, 27 had a history of clinically significant levels of aggression and other disruptive behaviors, and 30 were considered nonverbal at baseline. Etiology of the epilepsy was known in 32 cases, and included structural lesions, medical history, and developmental and genetic factors. Twenty-nine patients underwent resective treatments (in 8 cases combined with palliative procedures), 24 patients had only palliative treatments, and 3 patients had only subdural electroencephalography. Eighteen of the 56 patients had more than one operation. The mean age at surgery was 11 \u00b1 6.5 years (range 1.5-35 years). At a mean follow-up of 47 \u00b1 30 months (range 2-117 months), seizure outcomes included 20 Engel Class I, 12 Engel Class II, 18 Engel Class III, and 3 Engel Class IV cases. The age and follow-up times are stated as the mean \u00b1 SD. Three patients were able to discontinue all antiepileptic drugs (AEDs). Aggression and other aberrant behaviors observed in the clinical setting improved in 24 patients. According to caregivers, most patients also experienced some degree of improvement in daily social and cognitive function. Three patients had no functional or behavioral changes associated with seizure reduction, and 2 patients experienced worsening of seizures and behavioral symptoms. CONCLUSIONS Epilepsy surgery in patients with autism is feasible, with no indication that the comorbidity of autism should preclude a good outcome. Resective and palliative treatments brought seizure freedom or seizure reduction to the majority of patients, although one-third of the patients in this study required more than one procedure to achieve worthwhile improvement in the long term, and few patients were able to discontinue all AEDs. The number of palliative procedures performed, the need for multiple interventions, and continued use of AEDs highlight the complex etiology of epilepsy in patients with autism spectrum disorder. These considerations underscore the need for continued analysis, review, and reporting of surgical outcomes in patients with autism, which may aid in better identification and management of surgical candidates. The reduction in aberrant behaviors observed in this series suggests that some behaviors previously attributed to autism may be associated with intractable epilepsy, and further highlights the need for systematic evaluation of the relationship between the symptoms of autism and refractory seizures.",
      "authors": [
        "Kokoszka, Malgosia A",
        "McGoldrick, Patricia E",
        "La Vega-Talbott, Maite",
        "Raynes, Hillary",
        "Palmese, Christina A",
        "Wolf, Steven M",
        "Harden, Cynthia L",
        "Ghatan, Saadi"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3171/2016.7.PEDS1651",
      "keywords": [
        "N corpus callosotomy",
        "N ASD",
        "N MTS = mesial temporal sclerosis",
        "N vagus nerve stimulator",
        "N TS = tuberous sclerosis",
        "N epilepsy",
        "N EEG = electroencephalographic",
        "N VNS = vagus nerve stimulator",
        "N neuromodulation",
        "N palliative",
        "@UI",
        "N DSM-5 = Diagnostic and Statistical Manual, 5th Edition",
        "N autism spectrum disorder",
        "N PDD-NOS = pervasive developmental disorder, not otherwise specified",
        "N resective",
        "N VNS",
        "N AED = antiepileptic drug",
        "N MRE = medically refractory epilepsy",
        "N RNS = responsive neurostimulation",
        "N ASD = autism spectrum disorder",
        "#text"
      ],
      "number_of_pages": 12,
      "pages": "196-207",
      "publication": {
        "category": "Journal",
        "cite_score": 4.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1933-0715",
        "publisher": "American Association of Neurological Surgeons",
        "sjr": 0.812,
        "snip": 1.209,
        "subject_areas": [
          "Neurology (clinical)",
          "Pediatrics, Perinatology and Child Health",
          "Surgery"
        ],
        "title": "Journal of neurosurgery. Pediatrics"
      },
      "publication_date": "2016-11-25",
      "selected": false,
      "title": "Epilepsy surgery in patients with autism.",
      "urls": []
    },
    {
      "abstract": "Rehabilitation applications using brain-computer interfaces (BCI) have recently shown encouraging results for motor recovery. Effective BCI neurorehabilitation has been shown to exploit neuroplastic properties of the brain through mental imagery tasks. However, these applications and results are currently restricted to adults. A systematic search reveals there is essentially no literature describing motor rehabilitative BCI applications that use electroencephalograms (EEG) in children, despite advances in such applications with adults. Further inspection highlights limited literature pursuing research in the field, especially outside of neurofeedback paradigms. Then the question naturally arises, do current literature trends indicate that EEG based BCI motor rehabilitation applications could be translated to children? To provide further evidence beyond the available literature for this particular topic, we present an exploratory survey examining some of the indirect literature related to motor rehabilitation BCI in children. Our goal is to establish if evidence in the related literature supports research on this topic and if the related studies can help explain the dearth of current research in this area. The investigation found positive literature trends in the indirect studies which support translating these BCI applications to children and provide insight into potential pitfalls perhaps responsible for the limited literature. Careful consideration of these pitfalls in conjunction with support from the literature emphasize that fully realized motor rehabilitation BCI applications for children are feasible and would be beneficial. \u2022\u00a0 BCI intervention has improved motor recovery in adult patients and offer supplementary rehabilitation options to patients. \u2022\u00a0 A systematic literature search revealed that essentially no research has been conducted bringing motor rehabilitation BCI applications to children, despite advances in BCI. \u2022\u00a0 Indirect studies discovered from the systematic literature search, i.e. neurorehabilitation in children via BCI for autism spectrum disorder, provide insight into translating motor rehabilitation BCI applications to children. \u2022\u00a0 Translating BCI applications to children is a relevant, important area of research which is relatively barren.",
      "authors": [
        "Kinney-Lang, E",
        "Auyeung, B",
        "Escudero, J"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1088/1741-2560/13/6/061002",
      "keywords": [],
      "number_of_pages": null,
      "pages": "061002",
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1741-2552",
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Journal of neural engineering"
      },
      "publication_date": "2016-10-20",
      "selected": false,
      "title": "Expanding the (kaleido)scope: exploring current literature trends for translating electroencephalography (EEG) based brain-computer interfaces for motor rehabilitation in children.",
      "urls": []
    },
    {
      "abstract": "Motor balance in developmental stuttering (DS) was investigated with Transcranial Magnetic Stimulation (TMS), with the aim to define novel neural markers of persistent DS in adulthood. Eleven DS adult males were evaluated with TMS on tongue primary motor cortex, compared to 15 matched fluent speakers, in a \"state\" condition (i.e. stutterers vs. fluent speakers, no overt stuttering). Motor and silent period thresholds (SPT), recruitment curves, and silent period durations were acquired by recording tongue motor evoked potentials. Tongue silent period duration was increased in DS, especially in the left hemisphere (P<0.05; Hedge's g or Cohen's dunbiased = 1.054, i.e. large effect size), suggesting a \"state\" condition of higher intracortical inhibition in left motor cortex networks. Differences in motor thresholds (different excitatory/inhibitory ratios in DS) were evident, as well as significant differences in SPT. In fluent speakers, the left hemisphere may be marginally more excitable than the right one in motor thresholds at lower muscular activation, while active motor thresholds and SPT were higher in the left hemisphere of DS with respect to the right one, resulting also in a positive correlation with stuttering severity. Pre-TMS electromyography data gave overlapping evidence. Findings suggest the existence of a complex intracortical balance in DS tongue primary motor cortex, with a particular interplay between excitatory and inhibitory mechanisms, also in neural substrates related to silent periods. Findings are discussed with respect to functional and structural impairments in stuttering, and are also proposed as novel neural markers of a stuttering \"state\" in persistent DS, helping to define more focused treatments (e.g. neuro-modulation).",
      "authors": [
        "Busan, Pierpaolo",
        "Del Ben, Giovanni",
        "Bernardini, Simona",
        "Natarelli, Giulia",
        "Bencich, Marco",
        "Monti, Fabrizio",
        "Manganotti, Paolo",
        "Battaglini, Piero Paolo"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1371/journal.pone.0163959",
      "keywords": [],
      "number_of_pages": null,
      "pages": "e0163959",
      "publication": {
        "category": "Journal",
        "cite_score": 6.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1932-6203",
        "publisher": "Public Library of Science",
        "sjr": 0.885,
        "snip": 1.253,
        "subject_areas": [
          "Multidisciplinary"
        ],
        "title": "PloS one"
      },
      "publication_date": "2016-10-06",
      "selected": false,
      "title": "Altered Modulation of Silent Period in Tongue Motor Cortex of Persistent Developmental Stuttering in Relation to Stuttering Severity.",
      "urls": []
    },
    {
      "abstract": "Attention Deficit Hyperactivity Disorder (ADHD) is a common neuropsychiatric disorder that affects children and young adults. It results in significant impairment of their educational, social and occupational functioning and is associated economic societal burden. Whilst there are effective medications (such as methylphenidate) as well as some psychobehavioural therapies that can help with management of symptoms of ADHD, the former can have significant cardiac side effects, which limit their use. For number of patients these treatment options lack efficacy or are not acceptable. There is need to improve our understanding of neurobiology of ADHD as well as explore other treatment options. Transcranial magnetic stimulation (TMS) and repetitive transcranial magnetic stimulation (rTMS) are safe and non-invasive investigative and therapeutic tools respectively. In this short paper, I will explore the potential role of TMS and rTMS in further improving our understanding of the neurobiology of ADHD as well as possible treatment option.",
      "authors": [
        "Zaman, Rashid"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": null,
      "keywords": [],
      "number_of_pages": 4,
      "pages": "99-102",
      "publication": {
        "category": "Journal",
        "cite_score": 2.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "0353-5053",
        "publisher": "Medicinska Naklada Zagreb",
        "sjr": 0.407,
        "snip": 0.632,
        "subject_areas": [
          "Psychiatry and Mental Health"
        ],
        "title": "Psychiatria Danubina"
      },
      "publication_date": "2016-09-01",
      "selected": false,
      "title": "Investigative and therapeutic uses of Transcranial magnetic stimulation (TMS) in Attention Deficit Hyperactivity Disorder (ADHD).",
      "urls": []
    },
    {
      "abstract": "OBJECTIVE Among individuals at clinical high risk (CHR) for psychosis, processing speed (PS) has been related to social and role functioning regardless of conversion to schizophrenia. This information processing dysfunction is a gateway to broader behavioral deficits such as difficulty executing social behaviors. We examined the feasibility of improving information processing relevant to social situations in CHR, including its sustainability at 2-month follow-up, and its association with concurrent social function.\nMETHOD This was a double-blind RCT in which 62 CHR participants were randomized to Processing Speed Training (PST) or an active control matched for training format and the same dose and duration of treatment. PST is a tablet-based program that uses pupillometry-based neurofeedback to continually adjust training parameters for an optimal neurocognitive load and to improve visual scanning efficiency by inhibiting selection of nonessential targets and discriminating figure-ground details.\nRESULTS The PST group showed faster motoric and nonmotoric PS at post training and 2-month follow-up. At 2 month follow-up, the PST group reported better overall social adjustment. Changes in PS from baseline to 2 months were correlated with overall social adjustment and social avoidance in the entire sample.\nCONCLUSIONS AND IMPLICATIONS FOR PRACTICE This is the first study to test focal neurofeedback-based cognitive training for PS deficits in the putatively prodromal phase of schizophrenia to address associated social morbidity. Targeting PS appears to be a promising pathway to decreasing comorbidity and mitigating a risk factor for psychosis. (PsycINFO Database Record",
      "authors": [
        "Choi, Jimmy",
        "Corcoran, Cheryl M",
        "Fiszdon, Joanna M",
        "Stevens, Michael",
        "Javitt, Daniel C",
        "Deasy, Melissa",
        "Haber, Lawrence C",
        "Dewberry, Michael J",
        "Pearlson, Godfrey D"
      ],
      "categories": null,
      "citations": 39,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1037/prj0000217",
      "keywords": [
        "Clinical high risk for psychosis",
        "Pupillometry",
        "Cognitive remediation",
        "Neurofeedback"
      ],
      "number_of_pages": 10,
      "pages": "33-42",
      "publication": {
        "category": "Journal",
        "cite_score": 4.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1559-3126",
        "publisher": "Boston University",
        "sjr": 0.701,
        "snip": 1.088,
        "subject_areas": [
          "Health Professions  (miscellaneous)",
          "Rehabilitation",
          "Psychiatry and Mental Health"
        ],
        "title": "Psychiatric rehabilitation journal"
      },
      "publication_date": "2016-08-25",
      "selected": false,
      "title": "Pupillometer-based neurofeedback cognitive training to improve processing speed and social functioning in individuals at clinical high risk for psychosis.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85007228258&origin=inward"
      ]
    },
    {
      "abstract": "Impaired facial processing may contribute to social dysfunction in certain individuals with autism spectrum disorder (ASD). Prior studies show that electroencephalogram-based and functional magnetic resonance imaging-based neurofeedback might help some individuals with ASD learn to modulate regional brain activity and thus reduce symptoms. Here, we report for the first time the feasibility of employing functional near-infrared spectroscopy (fNIRS)-based neurofeedback training in children with ASD. We developed a method to study physiological self-regulation of oxy-hemoglobin using real-time feedback. The paradigm is illustrated with initial data from four subjects who engaged in a facial-identity recognition training program during which an implicit reinforcement was given based on the participant's brain activity and behavioral performance. Two participants had a confirmed diagnosis of ASD, and the other two were typically developing (TD). One participant with ASD and one TD participant received real-feedback (real-FB) during the training, whereas the other two received sham-feedback (sham-FB). After five training sessions, the subjects who received real-FB showed more improvement in facial recognition performance compared with those receiving sham-FB, particularly in the participant with ASD. These results suggest fNIRS-based neurofeedback could enhance therapeutic intervention in children with ASD. \u00c2\u00a9 The Authors.",
      "authors": [
        "Liu, Ning",
        "Cliffer, Sarit",
        "Pradhan, Anjali H",
        "Lightbody, Amy",
        "Hall, Scott S",
        "Reiss, Allan L"
      ],
      "categories": null,
      "citations": 21,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1117/1.NPh.4.1.011003",
      "keywords": [
        "@UI",
        "N autism",
        "N implicit reinforcement",
        "N neurofeedback",
        "N face recognition",
        "N functional near-infrared spectroscopy",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "011003",
      "publication": {
        "category": "Journal",
        "cite_score": 8.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2329-423X",
        "publisher": "SPIE",
        "sjr": 0.969,
        "snip": 1.337,
        "subject_areas": [
          "Radiological and Ultrasound Technology",
          "Neuroscience (miscellaneous)",
          "Radiology, Nuclear Medicine and Imaging"
        ],
        "title": "Neurophotonics"
      },
      "publication_date": "2016-08-17",
      "selected": false,
      "title": "Optical-imaging-based neurofeedback to enhance therapeutic intervention in adolescents with autism: methodology and initial data.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85006152461&origin=inward"
      ]
    },
    {
      "abstract": "Brain-machine interface-controlled (BMI) neurofeedback training aims to modulate cortical physiology and is applied during neurorehabilitation to increase the responsiveness of the brain to subsequent physiotherapy. In a parallel line of research, robotic exoskeletons are used in goal-oriented rehabilitation exercises for patients with severe motor impairment to extend their range of motion (ROM) and the intensity of training. Furthermore, neuromuscular electrical stimulation (NMES) is applied in neurologically impaired patients to restore muscle strength by closing the sensorimotor loop. In this proof-of-principle study, we explored an integrated approach for providing assistance as needed to amplify the task-related ROM and the movement-related brain modulation during rehabilitation exercises of severely impaired patients. For this purpose, we combined these three approaches (BMI, NMES, and exoskeleton) in an integrated neuroprosthesis and studied the feasibility of this device in seven severely affected chronic stroke patients who performed wrist flexion and extension exercises while receiving feedback via a virtual environment. They were assisted by a gravity-compensating, seven degree-of-freedom exoskeleton which was attached to the paretic arm. NMES was applied to the wrist extensor and flexor muscles during the exercises and was controlled by a hybrid BMI based on both sensorimotor cortical desynchronization (ERD) and electromyography (EMG) activity. The stimulation intensity was individualized for each targeted muscle and remained subthreshold, i.e., induced no overt support. The hybrid BMI controlled the stimulation significantly better than the offline analyzed ERD (p = 0.028) or EMG (p = 0.021) modality alone. Neuromuscular stimulation could be well integrated into the exoskeleton-based training and amplified both the task-related ROM (p = 0.009) and the movement-related brain modulation (p = 0.019). Combining a hybrid BMI with neuromuscular stimulation and antigravity assistance augments upper limb function and brain activity during rehabilitation exercises and may thus provide a novel restorative framework for severely affected stroke patients.",
      "authors": [
        "Grimm, Florian",
        "Walter, Armin",
        "Sp\u00fcler, Martin",
        "Naros, Georgios",
        "Rosenstiel, Wolfgang",
        "Gharabaghi, Alireza"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.3389/fnins.2016.00367",
      "keywords": [
        "N brain-robot interface",
        "N upper-limb assistance",
        "@UI",
        "N functional restoration",
        "N motor recovery",
        "N functional electrical stimulation",
        "N robot-assisted rehabilitation",
        "N brain-computer interface",
        "N brain-machine interface",
        "#text"
      ],
      "number_of_pages": null,
      "pages": "367",
      "publication": {
        "category": "Journal",
        "cite_score": 6.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1662-4548",
        "publisher": "Frontiers Media S.A.",
        "sjr": 1.161,
        "snip": 1.221,
        "subject_areas": [
          "Neuroscience (all)"
        ],
        "title": "Frontiers in neuroscience"
      },
      "publication_date": "2016-08-09",
      "selected": false,
      "title": "Hybrid Neuroprosthesis for the Upper Limb: Combining Brain-Controlled Neuromuscular Stimulation with a Multi-Joint Arm Exoskeleton.",
      "urls": []
    },
    {
      "abstract": "UNLABELLED Although economic theories suggest that punishment threat is crucial for maintaining social norms, counterexamples are noted in which punishment threat hinders norm compliance. Such discrepancy may arise from the intention behind the threat: unintentionally introduced punishment threat facilitates, whereas intentionally introduced punishment threat hinders, norm compliance. Here, we combined a dictator game and fMRI to investigate how intention modulates the effect of punishment threat on norm compliance and the neural substrates of this modulation. We also investigated whether this modulation can be influenced by brain stimulation. Human participants divided an amount of money between themselves and a partner. The partner (intentionally) or a computer program (unintentionally) decided to retain or waive the right to punish the participant upon selfish distribution. Compared with the unintentional condition, participants allocated more when the partner intentionally waived the power of punishment, but less when the partner retained such power. The right lateral orbitofrontal cortex (rLOFC) showed higher activation when the partner waived compared with when the computer waived or when the partner retained the power. The functional connectivity between the rLOFC and the brain network associated with intention/mentalizing processing was predictive of the allocation difference induced by intention. Moreover, inhibition or activation of the rLOFC by brain stimulation decreased or increased, respectively, the participants' reliance on the partner's intention during monetary allocation. These findings demonstrate that the perceived intention of punishment threat plays a crucial role in norm compliance and that the LOFC is casually involved in the implementation of intention-based cooperative decisions.\nSIGNIFICANCE STATEMENT Does punishment threat facilitate or hinder norm enforcement? So far, cognitive neuroscience research offers equivocal evidence. By directly manipulating the intention behind punishment threat, we demonstrate that intention modulates the effectiveness of punishment threat. Moreover, we show that inhibition or activation of the right lateral orbitofrontal cortex (rLOFC) decreased or increased the effect of punishment threat in the intentional context, but not in the unintentional context, suggesting the casual involvement of the rLOFC in intention-based cooperative decisions.",
      "authors": [
        "Zhang, Yuan",
        "Yu, Hongbo",
        "Yin, Yunlu",
        "Zhou, Xiaolin"
      ],
      "categories": null,
      "citations": 18,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1523/JNEUROSCI.0595-16.2016",
      "keywords": [
        "D016428 Journal Article",
        "N tDCS",
        "N punishment threat",
        "D013485 Research Support, Non-U.S. Gov't",
        "N norm compliance",
        "N lateral orbitofrontal cortex",
        "N intention"
      ],
      "number_of_pages": 9192,
      "pages": "9217-9226",
      "publication": {
        "category": "Journal",
        "cite_score": 9.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1529-2401",
        "publisher": "Society for Neuroscience",
        "sjr": 2.35,
        "snip": 1.471,
        "subject_areas": [
          "Neuroscience (all)"
        ],
        "title": "The Journal of neuroscience : the official journal of the Society for Neuroscience"
      },
      "publication_date": "2016-08-01",
      "selected": false,
      "title": "Intention Modulates the Effect of Punishment Threat in Norm Enforcement via the Lateral Orbitofrontal Cortex.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84985000703&origin=inward"
      ]
    },
    {
      "abstract": "OBJECTIVE Considering self-rated mental effort during neurofeedback may improve training of brain self-regulation.\nMETHODS Twenty-one healthy, right-handed subjects performed kinesthetic motor imagery of opening their left hand, while threshold-based classification of beta-band desynchronization resulted in proprioceptive robotic feedback. The experiment consisted of two blocks in a cross-over design. The participants rated their perceived mental effort nine times per block. In the adaptive block, the threshold was adjusted on the basis of these ratings whereas adjustments were carried out at random in the other block. Electroencephalography was used to examine the cortical activation patterns during the training sessions.\nRESULTS The perceived mental effort was correlated with the difficulty threshold of neurofeedback training. Adaptive threshold-setting reduced mental effort and increased the classification accuracy and positive predictive value. This was paralleled by an inter-hemispheric cortical activation pattern in low frequency bands connecting the right frontal and left parietal areas. Optimal balance of mental effort was achieved at thresholds significantly higher than maximum classification accuracy.\nCONCLUSION Rating of mental effort is a feasible approach for effective threshold-adaptation during neurofeedback training.\nSIGNIFICANCE Closed-loop adaptation of the neurofeedback difficulty level facilitates reinforcement learning of brain self-regulation.",
      "authors": [
        "Bauer, Robert",
        "Fels, Meike",
        "Royter, Vladislav",
        "Raco, Valerio",
        "Gharabaghi, Alireza"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.clinph.2016.06.020",
      "keywords": [
        "N Neurorehabilitation",
        "N Adaptive feedback",
        "N Brain-machine interface",
        "N Brain-computer interface",
        "#text",
        "N Brain-robot interface",
        "@UI"
      ],
      "number_of_pages": 9,
      "pages": "3156-3164",
      "publication": {
        "category": "Journal",
        "cite_score": 7.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1872-8952",
        "publisher": "Elsevier Ireland Ltd",
        "sjr": 1.212,
        "snip": 1.482,
        "subject_areas": [
          "Physiology (medical)",
          "Sensory Systems",
          "Neurology (clinical)",
          "Neurology"
        ],
        "title": "Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology"
      },
      "publication_date": "2016-06-27",
      "selected": false,
      "title": "Closed-loop adaptation of neurofeedback based on mental effort facilitates reinforcement learning of brain self-regulation.",
      "urls": []
    },
    {
      "abstract": "Favored by increased life expectancy and reduced birth rate, worldwide demography is rapidly shifting to older ages. The golden age of aging is not only an achievement but also a big challenge because of the load of the elderly on social and medical health care systems. Moreover, the impact of age-related decline of attention, memory, reasoning and executive functions on self-sufficiency emphasizes the need of interventions to maintain cognitive abilities at a useful degree in old age. Recently, neuroscientific research explored the chance to apply Non-Invasive Brain Stimulation (NiBS) techniques (as transcranial electrical and magnetic stimulation) to healthy aging population to preserve or enhance physiologically-declining cognitive functions. The present review will update and address the current state of the art on NiBS in healthy aging. Feasibility of NiBS techniques will be discussed in light of recent neuroimaging (either structural or functional) and neurophysiological models proposed to explain neural substrates of the physiologically aging brain. Further, the chance to design multidisciplinary interventions to maximize the efficacy of NiBS techniques will be introduced as a necessary future direction. \u00c2\u00a9 2016 Elsevier B.V.",
      "authors": [
        "Tatti, Elisa",
        "Rossi, Simone",
        "Innocenti, Iglis",
        "Rossi, Alessandro",
        "Santarnecchi, Emiliano"
      ],
      "categories": null,
      "citations": 65,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1016/j.arr.2016.05.006",
      "keywords": [
        "N Cognition",
        "D016428 Journal Article",
        "N tDCS",
        "D016454 Review",
        "N rTMS",
        "N Non-invasive brain stimulation",
        "N Healthy aging"
      ],
      "number_of_pages": 24,
      "pages": "66-89",
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1872-9649",
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Ageing research reviews"
      },
      "publication_date": "2016-05-21",
      "selected": false,
      "title": "Non-invasive brain stimulation of the aging brain: State of the art and future perspectives.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84977136734&origin=inward"
      ]
    },
    {
      "abstract": "Transcranial magnetic stimulation studies have so far reported the results of mapping the primary motor cortex (M1) for hand and tongue muscles in stuttering disorder. This study was designed to evaluate the feasibility of repetitive navigated transcranial magnetic stimulation (rTMS) for locating the M1 for laryngeal muscle and premotor cortical area in the caudal opercular part of inferior frontal gyrus, corresponding to Broca's area in stuttering subjects by applying new methodology for mapping these motor speech areas. Sixteen stuttering and eleven control subjects underwent rTMS motor speech mapping using modified patterned rTMS. The subjects performed visual object naming task during rTMS applied to the (a) left M1 for laryngeal muscles for recording corticobulbar motor-evoked potentials (CoMEP) from cricothyroid muscle and (b) left premotor cortical area in the caudal opercular part of inferior frontal gyrus while recording long latency responses (LLR) from cricothyroid muscle. The latency of CoMEP in control subjects was 11.75\u00a0\u00b1\u00a02.07\u00a0ms and CoMEP amplitude was 294.47\u00a0\u00b1\u00a0208.87\u00a0\u00b5V, and in stuttering subjects CoMEP latency was 12.13\u00a0\u00b1\u00a00.75\u00a0ms and 504.64\u00a0\u00b1\u00a0487.93\u00a0\u00b5V CoMEP amplitude. The latency of LLR in control subjects was 52.8\u00a0\u00b1\u00a08.6\u00a0ms and 54.95\u00a0\u00b1\u00a04.86 in stuttering subjects. No significant differences were found in CoMEP latency, CoMEP amplitude, and LLR latency between stuttering and control-fluent speakers. These results indicate there are probably no differences in stuttering compared to controls in functional anatomy of the pathway used for transmission of information from premotor cortex to the M1 cortices for laryngeal muscle representation and from there via corticobulbar tract to laryngeal muscles.",
      "authors": [
        "Rogi\u0107 Vidakovi\u0107, Maja",
        "Jerkovi\u0107, Ana",
        "Juri\u0107, Tomislav",
        "Vujovi\u0107, Igor",
        "\u0160oda, Jo\u0161ko",
        "Erceg, Nikola",
        "Bubi\u0107, Andreja",
        "Zmajevi\u0107 Sch\u00f6nwald, Marina",
        "Lioumis, Pantelis",
        "Gabelica, Dragan",
        "\u0110oga\u0161, Zoran"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1007/s10339-016-0766-5",
      "keywords": [
        "N Transcranial magnetic stimulation",
        "N Motor speech disorder",
        "N Premotor cortex",
        "N Laryngeal muscles",
        "#text",
        "N Primary motor cortex",
        "N Stuttering",
        "@UI"
      ],
      "number_of_pages": 14,
      "pages": "429-442",
      "publication": {
        "category": "Journal",
        "cite_score": 2.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1612-4790",
        "publisher": "Springer Verlag",
        "sjr": 0.476,
        "snip": 0.634,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Artificial Intelligence",
          "Experimental and Cognitive Psychology"
        ],
        "title": "Cognitive processing"
      },
      "publication_date": "2016-04-29",
      "selected": false,
      "title": "Neurophysiologic markers of primary motor cortex for laryngeal muscles and premotor cortex in caudal opercular part of inferior frontal gyrus investigated in motor speech disorder: a navigated transcranial magnetic stimulation (TMS) study.",
      "urls": []
    },
    {
      "abstract": "This pilot study aimed to investigate feasibility, acceptance, and effects of biofeedback-assisted mental training in a population of fifteen 10-year-old pupils in an Austrian elementary school. Participants were instructed in relaxation techniques by using biofeedback. Before intervention, after 6 weeks with active mental training and with regular instructions by the teacher, and after a further time period of 6 weeks without instructions, attention and concentration improved. The results indicate feasibility, good acceptance, and beneficial effects of biofeedback-assisted mental techniques in Austrian elementary school pupils. \u00c2\u00a9 2015, Springer-Verlag Wien.",
      "authors": [
        "Crevenna, R.",
        "Krammer, C.",
        "Keilani, M."
      ],
      "categories": null,
      "citations": 1,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1007/s10354-015-0397-y",
      "keywords": [
        "Mental techniques",
        "Biofeedback",
        "Prevention",
        "Elementary school",
        "Concentration"
      ],
      "number_of_pages": 3,
      "pages": "179-181",
      "publication": {
        "category": "Journal",
        "cite_score": 3.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "00435341",
        "publisher": "Springer-Verlag Wien",
        "sjr": 0.299,
        "snip": 0.795,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "Wiener Medizinische Wochenschrift"
      },
      "publication_date": "2016-04-01",
      "selected": false,
      "title": "Feasibility and acceptance of biofeedback-assisted mental training in an Austrian elementary school: a pilot study",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84946430748&origin=inward"
      ]
    },
    {
      "abstract": "Objectives: Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that consists of applying a weak electric current over the scalp to modulate cortical excitability. tDCS has been extensively investigated in adults with psychiatric disorders. The aim of this study was to review the current literature regarding the use of tDCS in children and adolescents with psychiatric disorders. Methods: We searched MEDLINE and EMBASE databases for studies evaluating the safety and efficacy of tDCS in children and adolescents from age 0 to 18 years with psychiatric disorders. Results: We found six studies that evaluated patients with different psychiatric disorders, with diverse study designs and stimulation parameters, including three small randomized clinical trials (RCTs), one evaluating childhood-onset schizophrenia, one RCT with patients with autism spectrum disorders (ASD), and one study in attention-deficit/hyperactivity disorder (ADHD); three open-label studies, two evaluating patients with ASD, and one study of feasibility of the technique in children and adolescents with language disorders and diverse psychiatric disorders, including ASD, intellectual disability, and ADHD. We also found three studies of dosage considerations in the general pediatric population. The technique was well tolerated, with no reports of serious side effects. Conclusion: Preliminary research suggests that tDCS may be well tolerated and safe for children and adolescents with psychiatric and neurodevelopmental disorders. Nevertheless, because the literature regarding tDCS in child and adolescent psychiatry is scarce and there exist limited numbers of randomized controlled trials, it is not possible to draw definite conclusions. Future studies should investigate the technique with regard to specific psychiatric conditions in comparison with standard treatments. In addition, long-term efficacy and safety should be monitored. \u00c2\u00a9 Mary Ann Liebert, Inc. 2016.",
      "authors": [
        "Muszkat, D\u00e9bora",
        "Polanczyk, Guilherme Vanoni",
        "Dias, Taciana G Costa",
        "Brunoni, Andr\u00e9 Russowsky"
      ],
      "categories": null,
      "citations": 31,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1089/cap.2015.0172",
      "keywords": [],
      "number_of_pages": 584,
      "pages": "590-597",
      "publication": {
        "category": "Journal",
        "cite_score": 4.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1557-8992",
        "publisher": "Mary Ann Liebert Inc.",
        "sjr": 0.774,
        "snip": 0.824,
        "subject_areas": [
          "Psychiatry and Mental Health",
          "Pediatrics, Perinatology and Child Health",
          "Pharmacology (medical)"
        ],
        "title": "Journal of child and adolescent psychopharmacology"
      },
      "publication_date": "2016-03-30",
      "selected": false,
      "title": "Transcranial Direct Current Stimulation in Child and Adolescent Psychiatry.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84988663834&origin=inward"
      ]
    },
    {
      "abstract": "Introduction: Text messaging (TMs) on cell phones is emerging as an effective means of delivering behavioral interventions. However, little is known about TM use in adult cancer patients. The present study aimed to extend knowledge on acceptability of a TM intervention in adult cancer patients; examine factors of those screened and enrolled; and compare recruitment at a large national specialty pharmacy versus community-based cancer clinics. Materials and Methods: Screening, enrollment, and baseline data collected in two randomized controlled trials examining the efficacy of TMs on medication adherence or symptom severity in adults prescribed oral anticancer agents were linked. Chi-square, Fisher's exact, t-tests, and generalized linear modeling were used to examine sociodemographics, cancer type and stage, depressive symptoms, self-efficacy, social support, and symptoms. Results: The cancer clinics screened 293 patients, 43% were eligible, and 56% consented. The specialty pharmacy screened 169 patients, 72% were eligible, and 74% consented. Mean age was 58 years and did not differ by recruitment setting. Later stage disease (p = 0.01) and higher number of symptoms (p < 0.01), and symptom severity (p = 0.02) and interference (p = 0.01) were observed among patients recruited at the specialty pharmacy. No group differences were found for depression, physical function, cognition, self-efficacy, or social support. Discussion: Adult cancer patients were likely to participate in a TM intervention trial. Recruiting through the specialty pharmacy reached a population with higher cell phone ownership and TM usage; with greater interest in a TM intervention compared to the cancer clinics. \u00c2\u00a9 Mary Ann Liebert, Inc. 2016.",
      "authors": [
        "Spoelstra, Sandra L",
        "Sikorskii, Alla",
        "Given, Charles W",
        "Coursaris, Constantinos K",
        "Majumder, Atreyee",
        "Schueller, Monica",
        "Given, Barbara A"
      ],
      "categories": null,
      "citations": 9,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1089/tmj.2015.0263",
      "keywords": [
        "D016428 Journal Article",
        "N oncology",
        "D003160 Comparative Study",
        "N randomized controlled trial",
        "N cancer",
        "D016449 Randomized Controlled Trial",
        "N recruitment",
        "N text messaging",
        "N m-health"
      ],
      "number_of_pages": 7,
      "pages": "836-842",
      "publication": {
        "category": "Journal",
        "cite_score": 8.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1556-3669",
        "publisher": "Mary Ann Liebert Inc.",
        "sjr": 1.237,
        "snip": 1.601,
        "subject_areas": [
          "Health Informatics",
          "Health Information Management"
        ],
        "title": "Telemedicine journal and e-health : the official journal of the American Telemedicine Association"
      },
      "publication_date": "2016-03-16",
      "selected": false,
      "title": "Adult Cancer Patient Recruitment and Enrollment into Cell Phone Text Message Trials.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84991491152&origin=inward"
      ]
    },
    {
      "abstract": "Purpose: Neurofeedback (NFB) training has demonstrated significant potential in achieving symptoms reduction in children with Autism Spectrum Disorder (ASD). However, children with low-functioning ASD are often uncooperative with the treatment. To evaluate whether NFB can eventually be administrated during sleep, a safety and feasibility pilot study was performed. Methods: A 9-year-old male patient diagnosed with ASD underwent NFB training for 30 min twice a week. This was operated at home during sleep by the parents. The NFB protocol aimed at increasing sensorimotor rhythm (SMR) while simultaneously decreasing theta activity over the sensorimotor strip. Results: NFB during sleep was feasible and did not yield adverse side effects. Parents reported improved behavioral and emotional symptoms and enhanced language development following NFB training. Subsequently, the patient could participate in regular sessions of NFB in wakefulness. Conclusion: Overall, parental reports suggest that applying NFB during sleep in low-functioning ASD is feasible and might offer promising therapeutic avenues. \u00c2\u00a9 2016. Avirame et al.",
      "authors": [
        "Avirame, K.",
        "Nuss, L.",
        "Todder, D."
      ],
      "categories": null,
      "citations": 1,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.15540/nr.3.3.135",
      "keywords": [
        "Sleep",
        "Autism",
        "Sensorimotor rhythm",
        "Neurofeedback"
      ],
      "number_of_pages": 5,
      "pages": "135-139",
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "NeuroRegulation"
      },
      "publication_date": "2016-01-01",
      "selected": false,
      "title": "Safety and feasibility of Neurofeedback Training (NFB) during sleep in uncooperative child with autism: Case report",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85046054186&origin=inward"
      ]
    },
    {
      "abstract": "Background: Patients with recent stroke or transient ischemic attack (TIA) have a high risk for recurrent vascular events. Multiple evidence- based strategies in secondary prevention are recommended but presumably not sufficiently utilized. Support programmes targeting vascular risk factors have been evaluated in prospective randomized trials for other diseases like diabetes mellitus or coronary heart disease. However, no such support programme has been investigated in patients after stroke. INSPiRE-TMS is a multicentre, prospective and randomized intervention trial for intensified secondary prevention after TIA or minor stroke. Methods: Patients with recent TIA or minor stroke are randomized in a 1:1 manner into an intervention (usual care plus support programme) and a control (usual care) arm. The trial will include 2 082 patients. The support programme consists of the following components: measurement of the vascular risk parameters, monitoring of the adherence to medication, counselling concerning lifestyle-modification and involvement of the relatives. Using standardized \"motivational interviewing\", the patients' motivation shall be consolidated and strengthened. Patients will be followed up for at least 2 years. Discussion: Through systematic implementation of available evidence- based strategies in secondary prevention, INSPiRE-TMS has the potential to reduce recurrent vascular events and to extend the event-free survival time in acute stroke patients. As a result, it will contribute to the decision, whether an intensified secondary prevention support programme after stroke should be implemented into regular care. \u00c2\u00a9 Schattauer 2016.",
      "authors": [
        "Laumeier, I.",
        "Audebert, H.J."
      ],
      "categories": null,
      "citations": 0,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1055/s-0037-1616353",
      "keywords": [],
      "number_of_pages": 6,
      "pages": "35-40",
      "publication": {
        "category": "Journal",
        "cite_score": 0.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "07221541",
        "publisher": "Georg Thieme Verlag",
        "sjr": 0.146,
        "snip": 0.138,
        "subject_areas": [
          "Family Practice",
          "Neurology (clinical)"
        ],
        "title": "Nervenheilkunde"
      },
      "publication_date": "2016-01-01",
      "selected": false,
      "title": "Concept of supported secondary prevention after stroke: Intensified secondary prevention intending a reduction of recurrent events in TIA and minor stroke patients (INSPiRE-TMS)",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84956649764&origin=inward"
      ]
    },
    {
      "abstract": "In recent years, discussion around memory modification interventions has gained attention. However, discussion around the use of memory interventions in the criminal justice system has been mostly absent. In this paper we start by highlighting the importance memory has for human well-being and personal identity, as well as its role within the criminal forensic setting; in particular, for claiming and accepting legal responsibility, for moral learning, and for retribution. We provide examples of memory interventions that are currently available for medical purposes, but that in the future could be used in the forensic setting to modify criminal offenders' memories. In this section we contrast the cases of (1) dampening and (2) enhancing memories of criminal offenders. We then present from a pragmatic approach some pressing ethical issues associated with these types of memory interventions. The paper ends up highlighting how these pragmatic considerations can help establish ethically justified criteria regarding the possibility of interventions aimed at modifying criminal offenders' memories.",
      "authors": [
        "Cabrera, Laura Y",
        "Elger, Bernice S"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1007/s11673-015-9680-2",
      "keywords": [
        "@UI",
        "N Memory",
        "N Retribution",
        "N Neuro-intervention",
        "N Criminal forensic setting",
        "N Criminal",
        "#text"
      ],
      "number_of_pages": 9,
      "pages": "95-103",
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1872-4353",
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Journal of bioethical inquiry"
      },
      "publication_date": "2015-12-29",
      "selected": false,
      "title": "Memory Interventions in the Criminal Justice System: Some Practical Ethical Considerations.",
      "urls": []
    },
    {
      "abstract": "For most people, adolescence is synonymous with emotional turmoil and it has been shown that early difficulties with emotion regulation can lead to persistent problems for some people. This suggests that intervention during development might reduce long-term negative consequences for those individuals. Recent research has highlighted the suitability of real-time fMRI-based neurofeedback (NF) in training emotion regulation (ER) networks in adults. However, its usefulness in directly influencing plasticity in the maturing ER networks remains unclear. Here, we used NF to teach a group of 17 7-16 year-olds to up-regulate the bilateral insula, a key ER region. We found that all participants learned to increase activation during the up-regulation trials in comparison to the down-regulation trials. Importantly, a subsequent Granger causality analysis of Granger information flow within the wider ER network found that during up-regulation trials, bottom-up driven Granger information flow increased from the amygdala to the bilateral insula and from the left insula to the mid-cingulate cortex, supplementary motor area and the inferior parietal lobe. This was reversed during the down-regulation trials, where we observed an increase in top-down driven Granger information flow to the bilateral insula from mid-cingulate cortex, pre-central gyrus and inferior parietal lobule. This suggests that: 1) NF training had a differential effect on up-regulation vs down-regulation network connections, and that 2) our training was not only superficially concentrated on surface effects but also relevant with regards to the underlying neurocognitive bases. Together these findings highlight the feasibility of using NF in children and adolescents and its possible use for shaping key social cognitive networks during development. \u00c2\u00a9 2015 The Authors.",
      "authors": [
        "Cohen Kadosh, Kathrin",
        "Luo, Qiang",
        "de Burca, Calem",
        "Sokunbi, Moses O",
        "Feng, Jianfeng",
        "Linden, David E J",
        "Lau, Jennifer Y F"
      ],
      "categories": null,
      "citations": 78,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1016/j.neuroimage.2015.09.070",
      "keywords": [],
      "number_of_pages": 11,
      "pages": "616-626",
      "publication": {
        "category": "Journal",
        "cite_score": 11.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1095-9572",
        "publisher": "Academic Press Inc.",
        "sjr": 2.512,
        "snip": 1.782,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Neurology"
        ],
        "title": "NeuroImage"
      },
      "publication_date": "2015-10-22",
      "selected": false,
      "title": "Using real-time fMRI to influence effective connectivity in the developing emotion regulation network.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84946887657&origin=inward"
      ]
    },
    {
      "abstract": "Staphylococcus aureus commonly infects medical implants or devices, with devastating consequences for the patient. The infection begins with bacterial attachment to the device, followed by bacterial multiplication over the surface of the device, generating an adherent sheet of bacteria known as a biofilm. Biofilms resist antimicrobial therapy and promote persistent infection, making management difficult to futile. Infections might be prevented by engineering the surface of the device to discourage bacterial attachment and multiplication; however, progress in this area has been limited. We have developed a novel nanoscale plasma coating technology to inhibit the formation of Staphylococcus aureus biofilms. We used monomeric trimethylsilane (TMS) and oxygen to coat the surfaces of silicone rubber, a material often used in the fabrication of implantable medical devices. By quantitative and qualitative analysis, the TMS/O2 coating significantly decreased the in vitro formation of S. aureus biofilms; it also significantly decreased in vivo biofilm formation in a mouse model of foreign-body infection. Further analysis demonstrated TMS/O2 coating significantly changed the protein adsorption, which could lead to reduced bacterial adhesion and biofilm formation. These results suggest that TMS/O2 coating can be used to effectively prevent medical implant-related infections. Copyright \u00c2\u00a9 2015, American Society for Microbiology. All Rights Reserved.",
      "authors": [
        "Xu, Yuanxi",
        "Jones, John E",
        "Yu, Haiqing",
        "Yu, Qingsong",
        "Christensen, Gordon D",
        "Chen, Meng",
        "Sun, Hongmin"
      ],
      "categories": null,
      "citations": 13,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1128/AAC.01944-15",
      "keywords": [],
      "number_of_pages": 7294,
      "pages": "7308-7315",
      "publication": {
        "category": "Journal",
        "cite_score": 10.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1098-6596",
        "publisher": "American Society for Microbiology",
        "sjr": 1.415,
        "snip": 1.175,
        "subject_areas": [
          "Pharmacology (medical)",
          "Pharmacology",
          "Infectious Diseases"
        ],
        "title": "Antimicrobial agents and chemotherapy"
      },
      "publication_date": "2015-09-14",
      "selected": false,
      "title": "Nanoscale Plasma Coating Inhibits Formation of Staphylococcus aureus Biofilm.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84954505316&origin=inward"
      ]
    },
    {
      "abstract": "Introduction or background Depression frequently fails to respond to initial treatment. Sources of data Predominantly meta-analyses and RCTs but supplemented where necessary by additional data and the authors' clinical experience. Areas of agreement A systematic assessment to identify remedial causes of poor response should be followed by planned sequential treatment trials. Joint decision making by the patient and clinician is essential. Strategies with the strongest support are antidepressant augmentation with lithium or second generation antipsychotics and adding cognitive behavioural treatment. Electroconvulsive therapy is highly effective in resistant depression but there is a high relapse rate when treatment ends. Areas of controversy Some pharmacological strategies have inconsistent data (e.g. antidepressant combinations, T3 augmentation) or limited preliminary data (e.g. ketamine, antidepressant augmentation with pramipexole). The efficacy of vagus nerve stimulation, deep brain stimulation and repetitive transcranial magnetic stimulation is unclear. Growing points A greater understanding of the causes of depression may assist the development of more effective treatments. Areas timely for developing research Role of glutamate antagonists and psychological treatments, other than cognitive behavioural therapy, as adjunctive treatments. \u00c2\u00a9 2015 The Author 2015.",
      "authors": [
        "Haddad, P.M.",
        "Talbot, P.S.",
        "Anderson, I.M.",
        "McAllister-Williams, R.H."
      ],
      "categories": null,
      "citations": 14,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1093/bmb/ldv034",
      "keywords": [
        "ECT",
        "lithium",
        "antidepressants",
        "treatment resistance",
        "depression",
        "neurostimulation therapies",
        "antipsychotics"
      ],
      "number_of_pages": 19,
      "pages": "183-201",
      "publication": {
        "category": "Journal",
        "cite_score": 10.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "00071420",
        "publisher": "Oxford University Press",
        "sjr": 1.593,
        "snip": 2.175,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "British Medical Bulletin"
      },
      "publication_date": "2015-09-01",
      "selected": false,
      "title": "Managing inadequate antidepressant response in depressive illness",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84941195737&origin=inward"
      ]
    },
    {
      "abstract": "OBJECTIVES OBJECTIVE To evaluate the safety, efficacy, and feasibility of inhibitory transcranial direct current stimulation (tDCS) for the treatment of behavioural abnormalities of autistic patients.\nMETHODS METHODS Twelve young adult patients with autistic disorder were enrolled. All subjects presented intellectual disability and most of them had speech impairment. The Aberrant Behavior Checklist (ABC) was administered as the primary outcome measure before and after a 2-week tDCS course. All subjects received 10 daily applications of 20 min/1.5 mA/cathodal (inhibitory) tDCS over the left dorso-lateral pre-frontal cortex.\nRESULTS RESULTS Eight out of 10 study completers improved in their abnormal behaviours, reaching an average reduction of 26.7% of the total ABC score. The remaining two patients showed no changes. In the whole group of completers, among the five subscales contributing to the significant reduction of the total score, the most remarkable and statistically significant change was seen in the subscale assessing hyperactivity and non-compliance (-35.9%, P = 0.002). No adverse effects were reported.\nCONCLUSIONS CONCLUSIONS Inhibitory tDCS improved the ABC rating scores for autistic behaviours. Owing to its ease of use, cost-effectiveness and the limited availability of specific treatment strategies, tDCS might be a valid therapeutic option to be tested in autistic patients.",
      "authors": [
        "D'Urso, Giordano",
        "Bruzzese, Dario",
        "Ferrucci, Roberta",
        "Priori, Alberto",
        "Pascotto, Antonio",
        "Galderisi, Silvana",
        "Altamura, Alfredo Carlo",
        "Bravaccio, Carmela"
      ],
      "categories": null,
      "citations": 46,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.3109/15622975.2015.1014411",
      "keywords": [
        "@UI",
        "N pervasive developmental disorders",
        "N TMS",
        "N tDCS",
        "N autism",
        "N intellectual disability",
        "#text"
      ],
      "number_of_pages": 356,
      "pages": "361-366",
      "publication": {
        "category": "Journal",
        "cite_score": 6.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1814-1412",
        "publisher": "Taylor and Francis Ltd.",
        "sjr": 0.872,
        "snip": 0.985,
        "subject_areas": [
          "Biological Psychiatry",
          "Psychiatry and Mental Health"
        ],
        "title": "The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry"
      },
      "publication_date": "2015-03-24",
      "selected": true,
      "title": "Transcranial direct current stimulation for hyperactivity and noncompliance in autistic disorder.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84938231945&origin=inward"
      ]
    },
    {
      "abstract": "Novel neurotechnologies, such as brain-computer interfaces (BCI), are generating significant scientific and popular interest. A certain BCI technology, neurofeedback (NF), is increasingly used for managing the symptoms of many conditions, most notably attention deficit hyperactivity disorder (ADHD). Although growing evidence suggests that the method is promising, there is no consensus in the scientific literature about its efficacy, and different sources offer contradictory evaluations. Although neurofeedback has received comparatively little scholarly attention from ethicists, it presents numerous dilemmas that warrant consideration. While the method is already widely used and its acceptability can be expected to grow, the precise mechanism of action and possible adverse effects of neurofeedback are poorly understood at present. The current regulatory landscape of neurofeedback devices seems inadequate, and in particular, the growing commercialization of BCIs and lack of oversight over EEG-based toys and games present a challenge for neuroethical analysis.After a brief discussion of ADHD, and the emergence of neurofeedback, this chapter provides an overview of assessments of NF\u00e2\u0080\u0099s efficacy and a brief survey of some of the ethical and social aspects of the method for pediatric ADHD. The questions covered include adverse effects, regulation, responsible communication, identity considerations, and the enhancement use of BCIs. \u00c2\u00a9 Springer Science+Business Media Dordrecht 2015.",
      "authors": [
        "B\u00c3\u00a1rd, I.",
        "Singh, I."
      ],
      "categories": null,
      "citations": 2,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1007/978-94-007-4707-4_124",
      "keywords": [],
      "number_of_pages": 22,
      "pages": "741-762",
      "publication": {
        "category": "Book",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": "9789400747074",
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Handbook of Neuroethics"
      },
      "publication_date": "2015-01-01",
      "selected": false,
      "title": "Attention deficit hyperactivity disorder: Improving performance through brain\u2013computer interface",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84944536955&origin=inward"
      ]
    },
    {
      "abstract": "The identification and interpretation of facial expressions is an important feature of social cognition. This characteristic is often impaired in various neurodevelopmental disorders. Recent therapeutic approaches to intervene in social communication impairments include neurofeedback (NF). In this study, we present a NF real-time functional Magnetic Resonance Imaging (rt-fMRI), combined with electroencephalography (EEG) to train social communication skills. In this sense, we defined the right Superior Temporal Sulcus as our target region-of-interest. To analyze the correlation between the fMRI regions of interest and the EEG data, we transposed the sources located at the nearest cortical location to the target region. We extracted a set of 75 features from EEG segments and performed a correlation analysis with the brain activations extracted from rt-fMRI in the right pSTS region. The finding of significant correlations of simultaneously measured signals in distinct modalities (EEG and fMRI) is promising. Future studies should address whether the observed correlation levels between local brain activity and scalp measures are sufficient to implement NF approaches. \u00c2\u00a9 2015 IEEE.",
      "authors": [
        "Simoes, Sim\u00f5es",
        "Lima, Jo\u00e3o",
        "Direito, Bruno",
        "Castelhano, Jo\u00e3o",
        "Ferreira, Carlos",
        "Carvalho, Paulo",
        "Castelo-Branco, Miguel"
      ],
      "categories": null,
      "citations": 8,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1109/EMBC.2015.7319287",
      "keywords": [],
      "number_of_pages": 4058,
      "pages": "4065-4068",
      "publication": {
        "category": "Journal",
        "cite_score": 2.4,
        "is_potentially_predatory": false,
        "isbn": "9781728111797",
        "issn": "2694-0604",
        "publisher": "Institute of Electrical and Electronics Engineers Inc.",
        "sjr": 0.188,
        "snip": 0.938,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference"
      },
      "publication_date": "2015-01-01",
      "selected": false,
      "title": "Feature analysis for correlation studies of simultaneous EEG-fMRI data: A proof of concept for neurofeedback approaches.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84953265387&origin=inward"
      ]
    },
    {
      "abstract": "Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that can modulate cortical excitability. Although the clinical value of tDCS has been advocated, the potential of tDCS in cognitive rehabilitation of face processing deficits is less understood. Face processing has been associated with the occipito-temporal cortex (OT). The present study investigated whether face processing in healthy adults can be modulated by applying tDCS over the OT. Experiment 1 investigated whether tDCS can affect N170, a face-sensitive ERP component, with a face orientation judgment task. The N170 in the right hemisphere was reduced in active stimulation conditions compared with the sham stimulation condition for both upright faces and inverted faces. Experiment 2 further demonstrated that tDCS can modulate the composite face effect, a type of holistic processing that reflects the obligatory attention to all parts of a face. The composite face effect was reduced in active stimulation conditions compared with the sham stimulation condition. Additionally, the current polarity did not modulate the effect of tDCS in the two experiments. The present study demonstrates that N170 can be causally manipulated by stimulating the OT with weak currents. Furthermore, our study provides evidence that obligatory attention to all parts of a face can be affected by the commonly used tDCS parameter setting.",
      "authors": [
        "Yang, Li-Zhuang",
        "Zhang, Wei",
        "Shi, Bin",
        "Yang, Zhiyu",
        "Wei, Zhengde",
        "Gu, Feng",
        "Zhang, Jing",
        "Cui, Guanbao",
        "Liu, Ying",
        "Zhou, Yifeng",
        "Zhang, Xiaochu",
        "Rao, Hengyi"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1371/journal.pone.0115772",
      "keywords": [],
      "number_of_pages": null,
      "pages": "e115772",
      "publication": {
        "category": "Journal",
        "cite_score": 6.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1932-6203",
        "publisher": "Public Library of Science",
        "sjr": 0.885,
        "snip": 1.253,
        "subject_areas": [
          "Multidisciplinary"
        ],
        "title": "PloS one"
      },
      "publication_date": "2014-12-22",
      "selected": false,
      "title": "Electrical stimulation over bilateral occipito-temporal regions reduces N170 in the right hemisphere and the composite face effect.",
      "urls": []
    },
    {
      "abstract": "Background: Treatment for children with attention deficit/hyperactivity disorder (ADHD) today is predominantly pharmacological. While it is the most common treatment, it might not always be the most appropriate one.Moreover, long term effects remain unclear. Behavior therapy (BT) and non-pharmacological treatments such as neurofeedback (NF) are promising alternatives, though there are no routine outpatient care/effectiveness studies yet that have included children with medication or changes in medication.Methods/design: This paper presents the protocol of a randomized controlled trial to compare the effectiveness of a Slow Cortical Potential (SCP) NF protocol with self-management (SM) in a high frequent outpatient care setting.Both groups (NF/SM) receive a total of 30 high frequent therapy sessions. Additionally, 6 sessions are reserved for comorbid problems. The primary outcome measure is the reduction of ADHD core symptoms according to parent and teacher ratings.Preliminary Results: Untill now 58 children were included in the study (48 males), with a mean age of 8.42 (1.34) years, and a mean IQ of 110 (13.37).Conners-3 parent and teacher ratings were used to estimate core symptom change. Since the study is still ongoing, and children are in different study stages, pre-post and follow-up results are not yet available for all children included. Preliminary results suggest overall good pre-post effects, though. For parent and teacher ratings an ANOVA with repeated measures yielded overall satisfying pre-post effects (\u00ce\u00b72 0.175\u00e2\u0080\u00930.513). Differences between groups (NF vs.SM) could not yet be established (p = 0.81).Discussion: This is the first randomized controlled trial to test the effectiveness of a NF protocol in a high frequent outpatient care setting that does not exclude children on or with changes in medication. First preliminary results show positive effects. The rationale for the trial, the design, and the strengths and limitations of the study are discussed. Trial registration: This trial is registered in www.clinicaltrials.gov as NCT01879644. \u00c2\u00a9 2014 Frontiers Research Foundation. All rights reserved.",
      "authors": [
        "Christiansen, H.",
        "Reh, V.",
        "Schmidt, M.H.",
        "Rief, W."
      ],
      "categories": null,
      "citations": 29,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3389/fnhum.2014.00943",
      "keywords": [
        "Self-management",
        "Neurofeedback",
        "ADHD",
        "Slow cortical potential training",
        "Behavior therapy",
        "Effectiveness"
      ],
      "number_of_pages": null,
      "pages": null,
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Frontiers in Human Neuroscience"
      },
      "publication_date": "2014-11-26",
      "selected": false,
      "title": "Slow cortical potential neurofeedback and self-management training in outpatient care for children with ADHD: Study protocol and first preliminary results of a randomized controlled trial",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84933673046&origin=inward"
      ]
    },
    {
      "abstract": "Human sensory and motor systems provide the natural means for the exchange of information between individuals, and, hence, the basis for human civilization. The recent development of brain-computer interfaces (BCI) has provided an important element for the creation of brain-to-brain communication systems, and precise brain stimulation techniques are now available for the realization of non-invasive computer-brain interfaces (CBI). These technologies, BCI and CBI, can be combined to realize the vision of non-invasive, computer-mediated brain-to-brain (B2B) communication between subjects (hyperinteraction). Here we demonstrate the conscious transmission of information between human brains through the intact scalp and without intervention of motor or peripheral sensory systems. Pseudo-random binary streams encoding words were transmitted between the minds of emitter and receiver subjects separated by great distances, representing the realization of the first human brain-to-brain interface. In a series of experiments, we established internet-mediated B2B communication by combining a BCI based on voluntary motor imagery-controlled electroencephalographic (EEG) changes with a CBI inducing the conscious perception of phosphenes (light flashes) through neuronavigated, robotized transcranial magnetic stimulation (TMS), with special care taken to block sensory (tactile, visual or auditory) cues. Our results provide a critical proof-of-principle demonstration for the development of conscious B2B communication technologies. More fully developed, related implementations will open new research venues in cognitive, social and clinical neuroscience and the scientific study of consciousness. We envision that hyperinteraction technologies will eventually have a profound impact on the social structure of our civilization and raise important ethical issues.",
      "authors": [
        "Grau, Carles",
        "Ginhoux, Romuald",
        "Riera, Alejandro",
        "Nguyen, Thanh Lam",
        "Chauvat, Hubert",
        "Berg, Michel",
        "Amengual, Juli\u00e0 L",
        "Pascual-Leone, Alvaro",
        "Ruffini, Giulio"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1371/journal.pone.0105225",
      "keywords": [],
      "number_of_pages": null,
      "pages": "e105225",
      "publication": {
        "category": "Journal",
        "cite_score": 6.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1932-6203",
        "publisher": "Public Library of Science",
        "sjr": 0.885,
        "snip": 1.253,
        "subject_areas": [
          "Multidisciplinary"
        ],
        "title": "PloS one"
      },
      "publication_date": "2014-08-19",
      "selected": false,
      "title": "Conscious brain-to-brain communication in humans using non-invasive technologies.",
      "urls": []
    },
    {
      "abstract": "Neurofeedback (NFB) is an emerging treatment for children with autism spectrum disorder (ASD). This pilot study examined the feasibility of NFB for children with ASD. Ten children ages 7-12 with high functioning ASD and attention difficulties received a NFB attention training intervention. A standardized checklist captured feasibility, including focus during exercises and academic tasks, as well as off-task behaviors. Active behaviors and vocalizations were the most frequent off-task behaviors. Positive reinforcement and breaks including calm breathing exercises were the most common supports. Low motivation was associated with higher feasibility challenges, yet parental involvement and accommodations were helpful. This pilot study shows that it is feasible to conduct NFB sessions with children with high functioning autism and attention difficulties. \u00c2\u00a9 2014 Springer Science+Business Media New York.",
      "authors": [
        "Steiner, Naomi J",
        "Frenette, Elizabeth",
        "Hynes, Caitlin",
        "Pisarik, Elizabeth",
        "Tomasetti, Kathryn",
        "Perrin, Ellen C",
        "Rene, Kirsten"
      ],
      "categories": null,
      "citations": 4,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1007/s10484-014-9241-1",
      "keywords": [
        "Autism spectrum disorder",
        "Biofeedback",
        "Neurofeedback"
      ],
      "number_of_pages": 9,
      "pages": "99-107",
      "publication": {
        "category": "Journal",
        "cite_score": 5.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1573-3270",
        "publisher": "Springer New York",
        "sjr": 0.534,
        "snip": 1.182,
        "subject_areas": [
          "Applied Psychology",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Applied psychophysiology and biofeedback"
      },
      "publication_date": "2014-06-01",
      "selected": true,
      "title": "A pilot feasibility study of neurofeedback for children with autism.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84901585975&origin=inward"
      ]
    },
    {
      "abstract": "Objective:Medication adherence is a complex behavior that is influenced by numerous factors. Applying self-efficacy theory, the primary aim of this randomized controlled trial was to compare medication self-efficacy among patients with coronary heart disease who received: (a) text messages (TMs) for medication reminders and education, (b) TMs for education, or (c) no TMs. The second aim was to identify the personal (sociodemographic and clinical characteristics) and psychosocial factors that were associated with and predicted medication adherence.Methods:Customized TMs were delivered over 30 days. Repeated measures analysis of variance was used to analyze medication self-efficacy. A multiple regression analysis was performed at baseline and follow-up to determine variables that were associated with and predicted self-reported medication adherence.Results:Among 90 subjects with mean age 59.2 years (standard deviation (SD) 9.4, range 35-83), total scores for medication self-efficacy improved over 30 days; however, there was no significant difference in this improvement as a function of the different treatment groups (p=0.64). Controlling for other variables in the model (age, education, depression, and social support), less depression (p=0.004) and higher social support (p=0.02) positively predicted higher medication adherence in the final model.Conclusions:TM medication reminders and/or health education did not improve medication self-efficacy. Further theory testing of current and future models and interventions are required to understand variables related to self-efficacy and medication adherence. Addressing psychosocial factors such as depression and social support should be a priority to improve medication adherence among patients with coronary heart disease. \u00c2\u00a9 The European Society of Cardiology 2014.",
      "authors": [
        "Park, Linda G",
        "Howie-Esquivel, Jill",
        "Whooley, Mary A",
        "Dracup, Kathleen"
      ],
      "categories": null,
      "citations": 45,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1177/1474515114537024",
      "keywords": [
        "N self-efficacy",
        "N social support",
        "D016428 Journal Article",
        "D003160 Comparative Study",
        "D013485 Research Support, Non-U.S. Gov't",
        "D016449 Randomized Controlled Trial",
        "N mobile health",
        "N coronary heart disease",
        "N text messaging",
        "N depression",
        "N Medication adherence"
      ],
      "number_of_pages": 192,
      "pages": "264-273",
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1873-1953",
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "European journal of cardiovascular nursing"
      },
      "publication_date": "2014-05-21",
      "selected": false,
      "title": "Psychosocial factors and medication adherence among patients with coronary heart disease: A text messaging intervention.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84930429488&origin=inward"
      ]
    },
    {
      "abstract": "This study focuses on a novel, easy to use and instruction-less method for mental training in athletes. Previous findings suggest that particular mental capacities are needed for achieving peak performance; including attentional control, focus, relaxation and positive affect. Electroencephalography (EEG) alpha brain activity has been associated with neural inhibition during processes of selective attention, for improving efficiency in information processing. Here we hypothesised that eyes open alpha power training by music teaches athletes to (1) learn to self-regulate their brain activity, and (2) learn to increase their baseline alpha power, herewith improving mental capacities such as focusing the allocation of attention. The study was double-blind and placebo-controlled. Twelve elite gymnasts were either given eyes open alpha power training or random beta power training (controls). Results indicate small improvements in sleep quality, mental and physical shape. In our first attempt at getting a grip on mental capacities in athletes, we think this novel training method can be promising. Because gymnastics is one of the most mentally demanding sports, we value even small benefits for the athlete and consider them indicative for future research.",
      "authors": [
        "Dekker, Marian K J",
        "van den Berg, Berber R",
        "Denissen, Ad J M",
        "Sitskoorn, Margriet M",
        "van Boxtel, Geert J M"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1080/02640414.2014.906044",
      "keywords": [
        "D016428 Journal Article",
        "N eyes open alpha power training",
        "D013485 Research Support, Non-U.S. Gov't",
        "N neurofeedback",
        "N mental capacities",
        "N focus",
        "D018848 Controlled Clinical Trial",
        "N athletes"
      ],
      "number_of_pages": 1491,
      "pages": "1550-60",
      "publication": {
        "category": "Journal",
        "cite_score": 6.5,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1466-447X",
        "publisher": "Routledge",
        "sjr": 1.141,
        "snip": 1.653,
        "subject_areas": [
          "Orthopedics and Sports Medicine",
          "Physical Therapy, Sports Therapy and Rehabilitation"
        ],
        "title": "Journal of sports sciences"
      },
      "publication_date": "2014-05-01",
      "selected": false,
      "title": "Feasibility of eyes open alpha power training for mental enhancement in elite gymnasts.",
      "urls": []
    },
    {
      "abstract": "Recent research has shown that stimulating right lateral prefrontal cortex (rLPFC) via transcranial direct current stimulation (tDCS) changes social norm compliance in economic decisions, with different types of compliance affected in different ways. More broadly considering the norms involved in decision-making, and in particular expectations held by players, can help clarify the mechanisms underlying these results. \u00c2\u00a9 2014 Elsevier Ltd.",
      "authors": [
        "Sanfey, Alan G",
        "Stallen, Mirre",
        "Chang, Luke J"
      ],
      "categories": null,
      "citations": 38,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1016/j.tics.2014.01.011",
      "keywords": [],
      "number_of_pages": 169,
      "pages": "172-174",
      "publication": {
        "category": "Journal",
        "cite_score": 30.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1879-307X",
        "publisher": "Elsevier Ltd.",
        "sjr": 5.615,
        "snip": 6.454,
        "subject_areas": [
          "Cognitive Neuroscience",
          "Experimental and Cognitive Psychology",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Trends in cognitive sciences"
      },
      "publication_date": "2014-02-26",
      "selected": false,
      "title": "Norms and expectations in social decision-making.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84897038990&origin=inward"
      ]
    },
    {
      "abstract": "The central auditory system has a crucial role in tinnitus generation and maintenance. Curative treatments for tinnitus do not yet exist. However, recent attempts in the therapeutic application of both acoustic stimulation/training procedures and electric/magnetic brain stimulation techniques have yielded promising results. Here, for the first time we combined tailor-made notched music training (TMNMT) with transcranial direct current stimulation (tDCS) in an effort to modulate TMNMT efficacy in the treatment of 32 patients with tonal tinnitus and without severe hearing loss. TMNMT is characterized by regular listening to so-called notched music, which is generated by digitally removing the frequency band of one octave width centered at the individual tinnitus frequency. TMNMT was applied for 10 subsequent days (2.5 hours of daily treatment). During the initial 5 days of treatment and the initial 30 minutes of TMNMT sessions, tDCS (current strength: 2 mA; anodal (N = 10) vs. cathodal (N = 11) vs. sham (N = 11) groups) was applied simultaneously. The active electrode was placed on the head surface over left auditory cortex; the reference electrode was put over right supra-orbital cortex. To evaluate treatment outcome, tinnitus-related distress and perceived tinnitus loudness were assessed using standardized tinnitus questionnaires and a visual analogue scale. The results showed a significant treatment effect reflected in the Tinnitus Handicap Questionnaire that was largest after 5 days of treatment. This effect remained significant at the end of follow-up 31 days after treatment cessation. Crucially, tDCS did not significantly modulate treatment efficacy--it did not make a difference whether anodal, cathodal, or sham tDCS was applied. Possible explanations for the findings and functional modifications of the experimental design for future studies (e.g. the selection of control conditions) are discussed.",
      "authors": [
        "Teismann, Henning",
        "Wollbrink, Andreas",
        "Okamoto, Hidehiko",
        "Schlaug, Gottfried",
        "Rudack, Claudia",
        "Pantev, Christo"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1371/journal.pone.0089904",
      "keywords": [],
      "number_of_pages": null,
      "pages": "e89904",
      "publication": {
        "category": "Journal",
        "cite_score": 6.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1932-6203",
        "publisher": "Public Library of Science",
        "sjr": 0.885,
        "snip": 1.253,
        "subject_areas": [
          "Multidisciplinary"
        ],
        "title": "PloS one"
      },
      "publication_date": "2014-02-25",
      "selected": false,
      "title": "Combining transcranial direct current stimulation and tailor-made notched music training to decrease tinnitus-related distress--a pilot study.",
      "urls": []
    },
    {
      "abstract": "What if neurofeedback or other types of neurotechnological treatment, by itself or in combination with behavioral treatment, could achieve a successful \"rewiring\" of the psychopath's brain? Imagine that such treatments exist and that they provide a better long-term risk-minimizing strategy compared to imprisonment. Would it be ethical to offer such treatments as a condition of probation, parole, or (early) prison release? In this paper, I argue that it can be ethical to offer effective, non-invasive neurotechnological treatments to offenders as a condition of probation, parole, or (early) prison release provided that: (1) the status quo is in no way cruel, inhuman, degrading, or in some other way wrong, (2) the treatment option is in no way cruel, inhuman, degrading, or in some other way wrong, (3) the treatment is in the best interests of the offender, and (4) the offender gives his/her informed consent. \u00c2\u00a9 2014 Springer Science+Business Media Dordrecht.",
      "authors": [
        "Focquaert, Farah"
      ],
      "categories": null,
      "citations": 21,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1007/s11017-014-9276-6",
      "keywords": [
        "Neurofeedback",
        "Neurotechnological",
        "Offender",
        "Coercion",
        "Psychopathy",
        "Neuroethics"
      ],
      "number_of_pages": 14,
      "pages": "59-72",
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1573-0980",
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Theoretical medicine and bioethics"
      },
      "publication_date": "2014-02-01",
      "selected": false,
      "title": "Mandatory neurotechnological treatment: ethical issues.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84893763449&origin=inward"
      ]
    },
    {
      "abstract": "Epilepsy is one of the most common serious neurological conditions, and 30 to 40% of people with epilepsy have seizures that are not controlled by medication. Patients are considered to have refractory epilepsy if disabling seizures continue despite appropriate trials of two antiseizure drugs, either alone or in combination. At this point, patients should be referred to multidisciplinary epilepsy centers that perform specialized diagnostic testing to first determine whether they are, in fact, pharmacoresistant, and then, if so, offer alternative treatments. Apparent pharmacoresistance can result from a variety of situations, including noncompliance, seizures that are not epileptic, misdiagnosis of the seizure type or epilepsy syndrome, inappropriate use of medication, and lifestyle issues. For patients who are pharmacoresistant, surgical treatment offers the best opportunity for complete freedom from seizures. Surgically remediable epilepsy syndromes have been identified, but patients with more complicated epilepsy can also benefit from surgical treatment and require more specialized evaluation, including intracranial EEG monitoring. For patients who are not surgical candidates, or who are unwilling to consider surgery, a variety of other alternative treatments can be considered, including peripheral or central neurostimulation, ketogenic diet, and complementary and alternative approaches. When such alternative treatments are not appropriate or effective, quality of life can still be greatly improved by the psychological and social support services offered by multidisciplinary epilepsy centers. A major obstacle remains the fact that only a small proportion of patients with refractory epilepsy are referred for expert evaluation and treatment.",
      "authors": [
        "Engel, J."
      ],
      "categories": null,
      "citations": 75,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.4103/0972-2327.128644",
      "keywords": [
        "ketogenic diet",
        "diagnostic approaches",
        "Complementary and alternative medicine",
        "refractory epilepsy",
        "epilepsy surgery",
        "neurostimulation"
      ],
      "number_of_pages": null,
      "pages": "S12-S17",
      "publication": {
        "category": "Journal",
        "cite_score": 2.3,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "09722327",
        "publisher": "Wolters Kluwer Medknow Publications",
        "sjr": 0.334,
        "snip": 0.654,
        "subject_areas": [
          "Neurology (clinical)"
        ],
        "title": "Annals of Indian Academy of Neurology"
      },
      "publication_date": "2014-01-01",
      "selected": false,
      "title": "Approaches to refractory epilepsy",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84898740664&origin=inward"
      ]
    },
    {
      "abstract": "Chronic pain in children and adolescents is a growing problem and one that is increasingly being addressed with multidisciplinary treatment teams. This review summarizes different multidisciplinary clinics, focusing specifically on intensive pediatric pain rehabilitation centers. This review offers a summary of the challenges faced by these programs and areas for future study. \u00c2\u00a9 2013 Odell and Logan.",
      "authors": [
        "Odell, S.",
        "Logan, D.E."
      ],
      "categories": null,
      "citations": 75,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.2147/JPR.S37434",
      "keywords": [
        "Pain associated disability",
        "Pediatric pain rehabilitation",
        "Pediatric chronic pain",
        "Interdisciplinary"
      ],
      "number_of_pages": 6,
      "pages": "785-790",
      "publication": {
        "category": "Journal",
        "cite_score": 4.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "11787090",
        "publisher": "Dove Medical Press Ltd.",
        "sjr": 0.667,
        "snip": 1.083,
        "subject_areas": [
          "Anesthesiology and Pain Medicine"
        ],
        "title": "Journal of Pain Research"
      },
      "publication_date": "2013-11-26",
      "selected": false,
      "title": "Pediatric pain management: The multidisciplinary approach",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84888029433&origin=inward"
      ]
    },
    {
      "abstract": "Background: Deep brain stimulation (DBS) together with concurrent EEG recording has shown promise in the treatment of epilepsy. A novel device is capable of combining these 2 functions and may prove valuable in the treatment of epilepsy in dogs. However, stereotactic implantation of electrodes in dogs has not yet been evaluated. Objective: To evaluate the feasibility and safety of implanting stimulating and recording electrodes in the brain of normal dogs using the Brainsight system and to evaluate the function of a novel DBS and recording device. Animals: Four male intact Greyhounds, confirmed to be normal by clinical and neurologic examinations and hematology and biochemistry testing. Methods: MRI imaging of the brain was performed after attachment of fiducial markers. MRI scans were used to calculate trajectories for electrode placement in the thalamus and hippocampus, which was performed via burr hole craniotomy. Postoperative CT scanning was performed to evaluate electrode location and accuracy of placement was calculated. Serial neurologic examinations were performed to evaluate neurologic deficits and EEG recordings obtained to evaluate the effects of stimulation. Results: Electrodes were successfully placed in 3 of 4 dogs with a mean accuracy of 4.6 \u00c2\u00b1 1.5 mm. EEG recordings showed evoked potentials in response to stimulation with a circadian variation in time-to-maximal amplitude. No neurologic deficits were seen in any dog. Conclusions and Clinical Importance: Stereotactic placement of electrodes is safe and feasible in the dog. The development of a novel device capable of providing simultaneous neurostimulation and EEG recording potentially represents a major advance in the treatment of epilepsy. \u00c2\u00a9 2013 by the American College of Veterinary Internal Medicine.",
      "authors": [
        "Long, S",
        "Frey, S",
        "Freestone, D R",
        "LeChevoir, M",
        "Stypulkowski, P",
        "Giftakis, J",
        "Cook, M"
      ],
      "categories": null,
      "citations": 18,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1111/jvim.12235",
      "keywords": [
        "N Deep brain stimulation",
        "N Electroencephalography",
        "D016428 Journal Article",
        "D013485 Research Support, Non-U.S. Gov't",
        "N Epilepsy",
        "N Canine"
      ],
      "number_of_pages": 93,
      "pages": "189-197",
      "publication": {
        "category": "Journal",
        "cite_score": 5.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1939-1676",
        "publisher": "Wiley-Blackwell",
        "sjr": 1.171,
        "snip": 1.732,
        "subject_areas": [
          "Veterinary (all)"
        ],
        "title": "Journal of veterinary internal medicine"
      },
      "publication_date": "2013-11-16",
      "selected": false,
      "title": "Placement of deep brain electrodes in the dog using the Brainsight frameless stereotactic system: a pilot feasibility study.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84892476441&origin=inward"
      ]
    },
    {
      "abstract": "All known human societies have maintained social order by enforcing compliance with social norms. The biological mechanisms underlying norm compliance are, however, hardly understood. We show that the right lateral prefrontal cortex (rLPFC) is involved in both voluntary and sanction-induced norm compliance. Both types of compliance could be changed by varying the neural excitability of this brain region with transcranial direct current stimulation, but they were affected in opposite ways, suggesting that the stimulated region plays a fundamentally different role in voluntary and sanction-based compliance. Brain stimulation had a particularly strong effect on compliance in the context of socially constituted sanctions, whereas it left beliefs about what the norm prescribes and about subjectively expected sanctions unaffected. Our findings suggest that rLPFC activity is a key biological prerequisite for an evolutionarily and socially important aspect of human behavior.",
      "authors": [
        "Ruff, C C",
        "Ugazio, G",
        "Fehr, E"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1126/science.1241399",
      "keywords": [],
      "number_of_pages": 479,
      "pages": "482-4",
      "publication": {
        "category": "Journal",
        "cite_score": 59.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1095-9203",
        "publisher": "American Association for the Advancement of Science",
        "sjr": 13.328,
        "snip": 7.729,
        "subject_areas": [
          "Multidisciplinary"
        ],
        "title": "Science (New York, N.Y.)"
      },
      "publication_date": "2013-10-03",
      "selected": false,
      "title": "Changing social norm compliance with noninvasive brain stimulation.",
      "urls": []
    },
    {
      "abstract": "Psychiatric issues inherently accompany dermatologic disease in children and adolescents. With body image issues being of paramount importance to adolescents, perceived flaws may be accompanied by depression, anxiety, or loss of usual functioning. Children and adolescents also often have difficulties with treatment compliance. Often medical professionals separate symptoms into physical versus psychosomatic. This differentiation is not a useful dichotomy, and interventions should be aimed at both physical and emotional needs simultaneously. A collaborative team approach with both dermatologist and psychiatrist/psychologist addressing physical and emotional symptoms is therefore favored for desirable results. \u00c2\u00a9 2013 Elsevier Inc..",
      "authors": [
        "Perry, M.",
        "Streusand, W.C."
      ],
      "categories": null,
      "citations": 4,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1016/j.det.2012.12.012",
      "keywords": [
        "CBT",
        "Psychosomatic",
        "Atopic dermatitis",
        "Acne",
        "Collaborative",
        "Scratching"
      ],
      "number_of_pages": 9,
      "pages": "347-355",
      "publication": {
        "category": "Journal",
        "cite_score": 6.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "07338635",
        "publisher": "W.B. Saunders Ltd",
        "sjr": 1.018,
        "snip": 1.772,
        "subject_areas": [
          "Dermatology"
        ],
        "title": "Dermatologic Clinics"
      },
      "publication_date": "2013-04-01",
      "selected": false,
      "title": "The Role of Psychiatry and Psychology Collaboration in Pediatric Dermatology",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84875782200&origin=inward"
      ]
    },
    {
      "abstract": "The success of virtual communities (VCs) relies on collaboration and resource sharing principles, making trust a priority for each member. The work presented in this paper addresses the problem of trust management in open and decentralised virtual communities. We address this problem by proposing an Adaptive and Socially-Compliant Trust Management System (ASC-TMS) adopting a multi-agent based approach. Our proposal relies on the joint use of trust policies and meta-policies, which allow VC members to exhibit adaptive (i.e., in accordance with environment changes) and socially-compliant (i.e., in accordance with the collective policies specified by the community members) behaviour. The experiments reported in this paper focus on the socially-compliant aspect of ASC-TMS. They aim at evaluating different policy integration algorithms. \u00c2\u00a9 2013 - IOS Press and the authors. All rights reserved.",
      "authors": [
        "Yaich, R.",
        "Boissier, O.",
        "Picard, G.",
        "Jaillon, P."
      ],
      "categories": null,
      "citations": 7,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3233/WIA-130278",
      "keywords": [
        "Multi-agent systems",
        "Open innovation",
        "Virtual communities",
        "Policies",
        "Trust management"
      ],
      "number_of_pages": 24,
      "pages": "315-338",
      "publication": {
        "category": "Journal",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "15701263",
        "publisher": "IOS Press BV",
        "sjr": 1.018,
        "snip": 1.772,
        "subject_areas": [
          "Computer Networks and Communications",
          "Artificial Intelligence",
          "Software"
        ],
        "title": "Web Intelligence and Agent Systems"
      },
      "publication_date": "2013-01-01",
      "selected": false,
      "title": "Adaptiveness and social-compliance in trust management within virtual communities",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84898011052&origin=inward"
      ]
    },
    {
      "abstract": "OBJECTIVES OBJECTIVE To test the proof of principle that active anodal transcranial direct current stimulation (tDCS) applied to the motor cortex reduces pain significantly more than sham stimulation in a group of participants with chronic nonspecific low back pain.\nMETHODS METHODS The study utilized a within-participants sham-controlled, interrupted time series design. A sample of 8 participants was recruited. After 3 days of baseline measures, patients entered a 15-day experimental period (Mondays to Fridays) for 3 consecutive weeks. During this period each patient received sham stimulation daily until a randomly allocated day when active stimulation was commenced. Active stimulation was then given daily for the remaining days of the experimental period. Both the participants and the assessors were blinded. The primary outcomes were average pain intensity and unpleasantness in the last 24 hours measured using a visual analogue scale. Secondary outcomes included self-reported disability, depression and anxiety, a battery of cognitive tests to monitor for unwanted effects of stimulation, and patients' perceptions of whether they had received active or sham stimulation. Data were analyzed using generalized estimating equations.\nRESULTS RESULTS No significant effect was seen in the primary outcomes between active and sham stimulation (average pain intensity P = 0.821, unpleasantness P = 0.937) or across any other clinical variables. There was evidence that patients may have been able to distinguish between the active and sham conditions (P = 0.035).\nDISCUSSION CONCLUSIONS These results do not provide evidence that tDCS is effective in the treatment of chronic back pain. The use of a small convenience sample limits the generalizability of these findings and precludes definitive conclusions on the efficacy of tDCS in chronic nonspecific low back pain.",
      "authors": [
        "O'Connell, Neil E",
        "Cossar, John",
        "Marston, Louise",
        "Wand, Benedict M",
        "Bunce, David",
        "De Souza, Lorraine H",
        "Maskill, David W",
        "Sharp, Andrew",
        "Moseley, G Lorimer"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1097/AJP.0b013e318247ec09",
      "keywords": [],
      "number_of_pages": 9,
      "pages": "26-34",
      "publication": {
        "category": "Journal",
        "cite_score": 5.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1536-5409",
        "publisher": "Lippincott Williams and Wilkins Ltd.",
        "sjr": 0.786,
        "snip": 1.255,
        "subject_areas": [
          "Neurology (clinical)",
          "Anesthesiology and Pain Medicine"
        ],
        "title": "The Clinical journal of pain"
      },
      "publication_date": "2013-01-01",
      "selected": false,
      "title": "Transcranial direct current stimulation of the motor cortex in the treatment of chronic nonspecific low back pain: a randomized, double-blind exploratory study.",
      "urls": []
    },
    {
      "abstract": "Within the last 2 years the bulk of information on evidence based treatments in ADHD was reviewed quite intensively and new empirical studies could be added. This update reports comprehensively about actual and essential facts in the field related to brain development and sensitive periods, predictors of treatment, safety of medication, value of naturalistic studies, new drugs and complementary medicine, behavioral interventions including neurofeedback and psychosocial treatment, treatment of comorbidity, and ethical considerations including preventive aspects. The updated combination of well selected evidence based treatments (ie, pharma plus non-pharma) seems to be clinically and ethically recommended as also suggested by the European and American guidelines on ADHD. \u00c2\u00a9 The Author(s) 2012.",
      "authors": [
        "Rothenberger, A.",
        "Rothenberger, L.G."
      ],
      "categories": null,
      "citations": 5,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1007/s11940-012-0197-2",
      "keywords": [
        "Attention-deficit/hyperactivity disorder",
        "Treatment",
        "Drugs",
        "ADHD",
        "Ethics",
        "Behaviour therapy",
        "Ethical considerations",
        "Adolescents",
        "Children"
      ],
      "number_of_pages": 14,
      "pages": "594-607",
      "publication": {
        "category": "Journal",
        "cite_score": 6.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "10928480",
        "publisher": "Current Science, Inc.",
        "sjr": 0.696,
        "snip": 1.141,
        "subject_areas": [
          "Neurology (clinical)"
        ],
        "title": "Current Treatment Options in Neurology"
      },
      "publication_date": "2012-12-01",
      "selected": false,
      "title": "Updates on treatment of attention-deficit/hyperactivity disorder: Facts, comments, and ethical considerations",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84870831697&origin=inward"
      ]
    },
    {
      "abstract": "Biofilm formation on implantable medical devices is a major impediment to the treatment of nosocomial infections and promotes local progressive tissue destruction. Staphylococcus epidermidis infections are the leading cause of biofilm formation on indwelling devices. Bacteria in biofilms are highly resistant to antibiotic treatment, which in combination with the increasing prevalence of antibiotic resistance among human pathogens further complicates treatment of biofilm-related device infections. We have developed a novel plasma coating technology. Trimethylsilane (TMS) was used as a monomer to coat the surfaces of 316L stainless steel and grade 5 titanium alloy, which are widely used in implantable medical devices. The results of biofilm assays demonstrated that this TMS coating markedly decreased S. epidermidis biofilm formation by inhibiting the attachment of bacterial cells to the TMS-coated surfaces during the early phase of biofilm development. We also discovered that bacterial cells on the TMS-coated surfaces were more susceptible to antibiotic treatment than their counterparts in biofilms on uncoated surfaces. These findings suggested that TMS coating could result in a surface that is resistant to biofilm development and also in a bacterial community that is more sensitive to antibiotic therapy than typical biofilms. Copyright \u00c2\u00a9 2012, American Society for Microbiology. All Rights Reserved.",
      "authors": [
        "Ma, Y.",
        "Chen, M.",
        "Jones, J.E.",
        "Ritts, A.C.",
        "Yu, Q.",
        "Sun, H."
      ],
      "categories": null,
      "citations": 68,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1128/AAC.01739-12",
      "keywords": [],
      "number_of_pages": 15,
      "pages": "5923-5937",
      "publication": {
        "category": "Journal",
        "cite_score": 10.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "00664804",
        "publisher": "American Society for Microbiology",
        "sjr": 1.415,
        "snip": 1.175,
        "subject_areas": [
          "Pharmacology (medical)",
          "Pharmacology",
          "Infectious Diseases"
        ],
        "title": "Antimicrobial Agents and Chemotherapy"
      },
      "publication_date": "2012-11-01",
      "selected": false,
      "title": "Inhibition of Staphylococcus epidermidis biofilm by trimethylsilane plasma coating",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84868007929&origin=inward"
      ]
    },
    {
      "abstract": "Marine populations in Europe are in decline due to the unsuccessful results of the Common Fisheries Policy. By combining data of scientific recommendations from ICES, TACs approved and reported landings with an age-structured model, the objectives of this paper are to investigate the level of compliance of the TAC regulation, and the level of enforcement and its economic impact on fishery resources. The results presented here suggest that while there does not exist a regular pattern between TAC proposal and TAC approved, there is a clear pattern between TAC approved and reported landings. As a consequence, there is a regular lack of enforcement at national fisheries authority level. The paper also presents results of the recovery plans for the Southern hake and the Atlantic cod fisheries as case studies to illustrate the level of enforcement based on collusion between national fisheries advisers and industry. The results from both cases studies analyzed here indicate that drastic solutions could generate positive results for the recovery of the stocks, but perhaps they are not always the best measure in fisheries management due to the high economic losses for fishermen and social effects on coastal communities in the short and medium term. Finally, this work demonstrates that if the recovery plans had been implemented, the net present profits for both fisheries would have increased over time. \u00c2\u00a9 2012 Elsevier Ltd.",
      "authors": [
        "Da Rocha, J.-M.",
        "Cervi\u00c3\u00b1o, S.",
        "Villasante, S."
      ],
      "categories": null,
      "citations": 41,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1016/j.marpol.2012.02.025",
      "keywords": [
        "Common Fisheries Policy",
        "Atlantic cod (Gadus morhua) fisheries",
        "Southern Hake (Merluccius merluccius)",
        "Enforcement",
        "TAC regulation"
      ],
      "number_of_pages": 6,
      "pages": "1309-1314",
      "publication": {
        "category": "Journal",
        "cite_score": 7.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "0308597X",
        "publisher": "Elsevier Ltd.",
        "sjr": 1.034,
        "snip": 1.352,
        "subject_areas": [
          "Law",
          "Economics and Econometrics",
          "Environmental Science (all)",
          "Aquatic Science",
          "Management, Monitoring, Policy and Law"
        ],
        "title": "Marine Policy"
      },
      "publication_date": "2012-11-01",
      "selected": false,
      "title": "The Common Fisheries Policy: An enforcement problem",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84861672973&origin=inward"
      ]
    },
    {
      "abstract": "PURPOSE OF REVIEW OBJECTIVE To summarize the recent progress in the development of vestibular implants. The review is timely because of the recent advances in the field and because MED-EL has recently announced that they are developing a vestibular implant for clinical applications.\nRECENT FINDINGS RESULTS The handicap experienced by patients suffering from bilateral vestibulopathy has a strong negative impact on physical and social functioning that appears to justify a surgical intervention. Two different surgical approaches to insert electrodes to stimulate ampullary neurons have been shown to be viable. The three-dimensional vestibulo-ocular reflex in rhesus monkeys produced with a three-dimensional vestibular implant showed gains that were relatively normal during acute stimulation. Rotation cues provided by an implant interact with otolith cues in a qualitatively normal manner. The brain appears to adapt plastically to the cues provided via artificial electrical stimulation.\nSUMMARY CONCLUSIONS Research to date includes just a few human studies, but available data from both humans and animals support the technological and physiological feasibility of vestibular implants. Although vestibular implant users should not expect normal vestibular function - any more than cochlear implant users should expect normal hearing - data suggest that significant functional improvements are possible.",
      "authors": [
        "Merfeld, Daniel M",
        "Lewis, Richard F"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1097/MOO.0b013e328357630f",
      "keywords": [],
      "number_of_pages": 295,
      "pages": "386-92",
      "publication": {
        "category": "Journal",
        "cite_score": 2.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1531-6998",
        "publisher": "Lippincott Williams and Wilkins Ltd.",
        "sjr": 0.526,
        "snip": 1.357,
        "subject_areas": [
          "Surgery",
          "Otorhinolaryngology"
        ],
        "title": "Current opinion in otolaryngology & head and neck surgery"
      },
      "publication_date": "2012-10-01",
      "selected": false,
      "title": "Replacing semicircular canal function with a vestibular implant.",
      "urls": []
    },
    {
      "abstract": "Autism is a highly varied developmental disorder typically characterized by deficits in reciprocal social interaction, difficulties with verbal and nonverbal communication, and restricted interests and repetitive behaviors. Although a wide range of behavioral, pharmacological, and alternative medicine strategies have been reported to ameliorate specific symptoms for some individuals, there is at present no cure for the condition. Nonetheless, among the many incompatible observations about aspects of the development, anatomy, and functionality of the autistic brain, it is widely agreed that it is characterized by widespread aberrant connectivity. Such disordered connectivity, be it increased, decreased, or otherwise compromised, may complicate healthy synchronization and communication among and within different neural circuits, thereby producing abnormal processing of sensory inputs necessary for normal social life. It is widely accepted that the innate properties of brain electrical activity produce pacemaker elements and linked networks that oscillate synchronously or asynchronously, likely reflecting a type of functional connectivity. Using phase coherence in multiple frequency EEG bands as a measure of functional connectivity, studies have shown evidence for both global hypoconnectivity and local hyperconnectivity in individuals with ASD. However, the nature of the brain's experience-dependent structural plasticity suggests that these abnormal patterns may be reversed with the proper type of treatment. Indeed, neurofeedback (NF) training, an intervention based on operant conditioning that results in self-regulation of brain electrical oscillations, has shown promise in addressing marked abnormalities in functional and structural connectivity. It is hypothesized that neurofeedback produces positive behavioral changes in ASD children by normalizing the aberrant connections within and between neural circuits. NF exploits the brain's plasticity to normalize aberrant connectivity patterns apparent in the autistic brain. By grounding this training in known anatomical (e.g., mirror neuron system) and functional markers (e.g., mu rhythms) of autism, NF training holds promise to support current treatments for this complex disorder. The proposed hypothesis specifically states that neurofeedback-induced alpha mu (8-12Hz) rhythm suppression or desynchronization, a marker of cortical activation, should induce neuroplastic changes and lead to normalization in relevant mirroring networks that have been associated with higher-order social cognition.",
      "authors": [
        "Pineda, J A",
        "Juavinett, A",
        "Datko, M"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.mehy.2012.08.031",
      "keywords": [],
      "number_of_pages": 783,
      "pages": "790-8",
      "publication": {
        "category": "Journal",
        "cite_score": 7.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1532-2777",
        "publisher": "Churchill Livingstone",
        "sjr": 0.619,
        "snip": 0.749,
        "subject_areas": [
          "Medicine (all)"
        ],
        "title": "Medical hypotheses"
      },
      "publication_date": "2012-09-20",
      "selected": false,
      "title": "Self-regulation of brain oscillations as a treatment for aberrant brain connections in children with autism.",
      "urls": []
    },
    {
      "abstract": "BACKGROUND BACKGROUND Impairment of the arterial baroreflex causes orthostatic hypotension. Arterial baroreceptor sensitivity degrades with age. Thus, an impaired baroreceptor plays a pivotal role in orthostatic hypotension in most elderly patients. There is no effective treatment for orthostatic hypotension. The aims of this investigation were to develop a bionic baroreceptor (BBR) and to verify whether it corrects postural hypotension.\nMETHODS AND RESULTS RESULTS The BBR consists of a pressure sensor, a regulator, and a neurostimulator. In 35 Sprague-Dawley rats, we vascularly and neurally isolated the baroreceptor regions and attached electrodes to the aortic depressor nerve for stimulation. To mimic impaired baroreceptors, we maintained intracarotid sinus pressure at 60 mm Hg during activation of the BBR. Native baroreflex was reproduced by matching intracarotid sinus pressure to the instantaneous pulsatile aortic pressure. The encoding rule for translating intracarotid sinus pressure into stimulation of the aortic depressor nerve was identified by a white noise technique and applied to the regulator. The open-loop arterial pressure response to intracarotid sinus pressure (n=7) and upright tilt-induced changes in arterial pressure (n=7) were compared between native baroreceptor and BBR conditions. The intracarotid sinus pressure-arterial pressure relationships were comparable. Compared with the absence of baroreflex, the BBR corrected tilt-induced hypotension as effectively as under native baroreceptor conditions (native, -39\u00b15 mm Hg; BBR, -41\u00b15 mm Hg; absence, -63\u00b15 mm Hg; P<0.05).\nCONCLUSIONS CONCLUSIONS The BBR restores the pressure buffering function. Although this research demonstrated feasibility of the BBR, further research is needed to verify its long-term effect and safety in larger animal models and humans.",
      "authors": [
        "Hosokawa, Kazuya",
        "Ide, Tomomi",
        "Tobushi, Tomoyuki",
        "Sakamoto, Kazuo",
        "Onitsuka, Ken",
        "Sakamoto, Takafumi",
        "Fujino, Takeo",
        "Saku, Keita",
        "Sunagawa, Kenji"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1161/CIRCULATIONAHA.112.108357",
      "keywords": [],
      "number_of_pages": 1194,
      "pages": "1278-85",
      "publication": {
        "category": "Journal",
        "cite_score": 42.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1524-4539",
        "publisher": "Lippincott Williams and Wilkins Ltd.",
        "sjr": 7.8,
        "snip": 6.144,
        "subject_areas": [
          "Physiology (medical)",
          "Cardiology and Cardiovascular Medicine"
        ],
        "title": "Circulation"
      },
      "publication_date": "2012-07-31",
      "selected": false,
      "title": "Bionic baroreceptor corrects postural hypotension in rats with impaired baroreceptor.",
      "urls": []
    },
    {
      "abstract": "BACKGROUND BACKGROUND Gastric stimulation via high-frequency, low-energy pulses can provide an effective treatment for gastric dysmotility; however, the current commercially available device requires surgical implantation for long-term stimulation and is powered by a nonrechargeable battery.\nOBJECTIVE OBJECTIVE To test and describe endoscopic implantation techniques and testing of stimulation of a novel, wireless, batteryless, gastric electrical stimulation (GES) device.\nDESIGN METHODS Endoscopic gastric implantation techniques were implemented, and in vivo gastric signals were recorded and measured in a non-survival swine model (n = 2; 50-kg animals).\nINTERVENTION METHODS Five novel endoscopic gastric implantation techniques and stimulation of a novel, wireless, batteryless, GES device were tested on a non-survival swine model.\nMAIN OUTCOME MEASUREMENTS METHODS Feasibility of 5 new endoscopic gastric implantation techniques of the novel, miniature, batteryless, wireless GES device while recording and measurement of in vivo gastric signals.\nRESULTS RESULTS All 5 of the novel endoscopic techniques permitted insertion and securing of the miniaturized gastrostimulator. By the help of these methods and miniaturization of the gastrostimulator, successful GES could be provided without any surgery. The metallic clip attachment was restricted to the mucosal surface, whereas the prototype tacks, prototype spring coils, percutaneous endoscopic gastrostomy wires/T-tag fasteners, and submucosal pocket endoscopic implantation methods attach the stimulator near transmurally or transmurally to the stomach. They allow more secure device attachment with optimal stimulation depth.\nLIMITATIONS CONCLUSIONS Non-survival pig studies.\nCONCLUSION CONCLUSIONS These 5 techniques have the potential to augment the utility of GES as a treatment alternative, to provide an important prototype for other dysmotility treatment paradigms, and to yield insights for new technological interfaces between non-invasiveness and surgery.",
      "authors": [
        "Deb, Sanchali",
        "Tang, Shou-jiang",
        "Abell, Thomas L",
        "McLawhorn, Tyler",
        "Huang, Wen-Ding",
        "Lahr, Christopher",
        "To, S D Filip",
        "Easter, Julie",
        "Chiao, J-C"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.gie.2012.03.177",
      "keywords": [],
      "number_of_pages": 96,
      "pages": "179-84",
      "publication": {
        "category": "Journal",
        "cite_score": 10.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1097-6779",
        "publisher": "Mosby Inc.",
        "sjr": 2.046,
        "snip": 2.7,
        "subject_areas": [
          "Gastroenterology",
          "Radiology, Nuclear Medicine and Imaging"
        ],
        "title": "Gastrointestinal endoscopy"
      },
      "publication_date": "2012-07-01",
      "selected": false,
      "title": "Development of innovative techniques for the endoscopic implantation and securing of a novel, wireless, miniature gastrostimulator (with videos).",
      "urls": []
    },
    {
      "abstract": "Many patients show no or incomplete responses to current pharmacological or psychological therapies for depression. Here we explored the feasibility of a new brain self-regulation technique that integrates psychological and neurobiological approaches through neurofeedback with functional magnetic resonance imaging (fMRI). In a proof-of-concept study, eight patients with depression learned to upregulate brain areas involved in the generation of positive emotions (such as the ventrolateral prefrontal cortex (VLPFC) and insula) during four neurofeedback sessions. Their clinical symptoms, as assessed with the 17-item Hamilton Rating Scale for Depression (HDRS), improved significantly. A control group that underwent a training procedure with the same cognitive strategies but without neurofeedback did not improve clinically. Randomised blinded clinical trials are now needed to exclude possible placebo effects and to determine whether fMRI-based neurofeedback might become a useful adjunct to current therapies for depression. \u00c2\u00a9 2012 Linden et al.",
      "authors": [
        "Linden, David E J",
        "Habes, Isabelle",
        "Johnston, Stephen J",
        "Linden, Stefanie",
        "Tatineni, Ranjit",
        "Subramanian, Leena",
        "Sorger, Bettina",
        "Healy, David",
        "Goebel, Rainer"
      ],
      "categories": null,
      "citations": 284,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1371/journal.pone.0038115",
      "keywords": [],
      "number_of_pages": null,
      "pages": "e38115",
      "publication": {
        "category": "Journal",
        "cite_score": 6.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1932-6203",
        "publisher": "Public Library of Science",
        "sjr": 0.885,
        "snip": 1.253,
        "subject_areas": [
          "Multidisciplinary"
        ],
        "title": "PloS one"
      },
      "publication_date": "2012-06-04",
      "selected": false,
      "title": "Real-time self-regulation of emotion networks in patients with depression.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84861842427&origin=inward"
      ]
    },
    {
      "abstract": "BACKGROUND BACKGROUND Gastric electric stimulation (GES) at a high-frequency, low-energy setting is an option for treating refractory gastroparesis. The currently available commercial stimulator, the Enterra neurostimulator (Medtronic Inc, Minneapolis, MN), however, requires surgical implantation and is powered by a nonrechargeable battery.\nOBJECTIVE OBJECTIVE To develop and test a miniature wireless GES device for endoscopic implantation in an experimental model.\nDESIGN METHODS In-vivo gastric signals were recorded and measured in a nonsurvival swine model (n = 2; 110-lb animals).\nINTERVENTION METHODS An endoscopically placed, wireless GES device was inserted into the stomach through an overtube; the two GES electrodes were endoscopically attached to the gastric mucosa and secured with endoclips to permit stimulation.\nMAIN OUTCOME MEASUREMENTS METHODS Stable electrogastrogram measures were observed during GES stimulation.\nRESULTS RESULTS Electrogastrogram recordings demonstrated that gastric slow waves became more regular and of constant amplitudes when stomach tissues were stimulated, in comparison with no stimulation. The frequency-to-amplitude ratio also changed significantly with stimulation.\nLIMITATION CONCLUSIONS Nonsurvival pig studies.\nCONCLUSION CONCLUSIONS Gastric electric stimulation is feasible by our endoscopically implanted, wireless GES device.",
      "authors": [
        "Deb, Sanchali",
        "Tang, Shou-Jiang",
        "Abell, Thomas L",
        "Rao, Smitha",
        "Huang, Wen-Ding",
        "To, S D Filip",
        "Lahr, Christopher",
        "Chiao, Jung-Chih"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1016/j.gie.2011.09.052",
      "keywords": [],
      "number_of_pages": null,
      "pages": "411-5, 415.e1",
      "publication": {
        "category": "Journal",
        "cite_score": 10.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1097-6779",
        "publisher": "Mosby Inc.",
        "sjr": 2.046,
        "snip": 2.7,
        "subject_areas": [
          "Gastroenterology",
          "Radiology, Nuclear Medicine and Imaging"
        ],
        "title": "Gastrointestinal endoscopy"
      },
      "publication_date": "2012-02-01",
      "selected": false,
      "title": "An endoscopic wireless gastrostimulator (with video).",
      "urls": []
    },
    {
      "abstract": "Gilles de la Tourette syndrome (TS) is characterized by motor and vocal tic manifestations, often accompanied by behavioral, cognitive and affective dysfunctions. Electroencephalography of patients with TS has revealed reduced Sensorimotor Rhythm (SMR) and excessive fronto-central Theta activity, that presumably underlie motor and cognitive disturbances in TS. Some evidence exists that neurofeedback (NFB) training aimed at enhancing SMR amplitude is effective for reducing tics. The present report is an uncontrolled single case study where a NFB training protocol, involving combined SMR uptraining/Theta downtraining was delivered to a 17-year-old male with TS. After sixteen SMR-Theta sessions, six additional sessions were administered with SMR uptraining alone. SMR increase was better obtained when SMR uptraining was administered alone, whereas Theta decrease was observed after both trainings. The patient showed a reduction of tics and affective symptoms, and improvement of cognitive performance after both trainings. Overall, these findings suggest that Theta decrease might account for some clinical effects seen in conjunction with SMR uptraining. Future studies should clarify the feasibility of NFB protocols for patients with TS beyond SMR uptraining alone. \u00c2\u00a9 2011 Springer Science+Business Media, LLC.",
      "authors": [
        "Messerotti Benvenuti, Simone",
        "Buodo, Giulia",
        "Leone, Valentino",
        "Palomba, Daniela"
      ],
      "categories": null,
      "citations": 18,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1007/s10484-011-9169-7",
      "keywords": [
        "Theta",
        "Neurofeedback",
        "Gilles de la Tourette",
        "QEEG",
        "SMR"
      ],
      "number_of_pages": 274,
      "pages": "281-288",
      "publication": {
        "category": "Journal",
        "cite_score": 5.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1573-3270",
        "publisher": "Springer New York",
        "sjr": 0.534,
        "snip": 1.182,
        "subject_areas": [
          "Applied Psychology",
          "Neuropsychology and Physiological Psychology"
        ],
        "title": "Applied psychophysiology and biofeedback"
      },
      "publication_date": "2011-12-01",
      "selected": false,
      "title": "Neurofeedback training for tourette syndrome: an uncontrolled single case study.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84855248895&origin=inward"
      ]
    },
    {
      "abstract": "Recent years witnessed an evergrowing impact of trust in the decision-making process within virtual communities. The inherent decentralized and open nature of such environments produced new challenges that received, up to now, little attention. For example, the individual and collective trust co-influence remains an unexplored issue. In this paper we are considering how user-centred and community-centred trust policies can be considered, managed and combined. To this aim, we propose a Socially-Compliant Trust Management Systems (SC-TMS) based on dynamic and adaptive trust policies and multi-agent technologies. \u00c2\u00a9 2011 IEEE.",
      "authors": [
        "Yaich, R.",
        "Boissier, O.",
        "Jaillon, P.",
        "Picard, G."
      ],
      "categories": null,
      "citations": 3,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1109/WI-IAT.2011.212",
      "keywords": [
        "Virtual communities",
        "Multi-agent systems",
        "Trust management",
        "Trust policies"
      ],
      "number_of_pages": 4,
      "pages": "322-325",
      "publication": {
        "category": "Conference Proceedings",
        "cite_score": null,
        "is_potentially_predatory": false,
        "isbn": "9780769545134",
        "issn": null,
        "publisher": null,
        "sjr": null,
        "snip": null,
        "subject_areas": [],
        "title": "Proceedings - 2011 IEEE/WIC/ACM International Joint Conferences on Web Intelligence and Intelligent Agent Technology - Workshops, WI-IAT 2011"
      },
      "publication_date": "2011-11-07",
      "selected": false,
      "title": "Social-Compliance in Trust Management within virtual communities",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=80155129601&origin=inward"
      ]
    },
    {
      "abstract": "The allocation of individual transferable quotas (ITQs) as shares of a total allowable catch (TAC) is now widely practised in fisheries management, but is not without controversy. It is often suggested that the possession of ITQs should provide an incentive for fishers to exercise stewardship of the resource. Quota holders acting in their economic self-interest should collectively exercise stewardship, setting TACs and supporting enforcement measures to maximize the present value of future profit streams. But it is in the economic self-interest of an individual fisher possessing ITQ to take additional unreported catch, through discarding, high-grading, or quota-busting. Thus, ITQs in themselves will not prevent a \"tragedy of the commons\", unless there is sufficient compliance monitoring and enforcement to deter hidden catches. ITQs, with adequate enforcement, have been demonstrated to effectively address the race to fish and result in improved sustainability and profitability. There are questions of equity concerning the flow of benefits from the allocations of quotas and associated profit streams and who pays for the management costs required to sustain them. There are also issues around the ability of ITQ-based management to address other social and environmental objectives.",
      "authors": [
        "Parslow, J."
      ],
      "categories": null,
      "citations": 19,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1139/F10-104",
      "keywords": [],
      "number_of_pages": 8,
      "pages": "1889-1896",
      "publication": {
        "category": "Journal",
        "cite_score": 4.9,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "0706652X",
        "publisher": "National Research Council of Canada",
        "sjr": 0.816,
        "snip": 0.965,
        "subject_areas": [
          "Ecology, Evolution, Behavior and Systematics",
          "Aquatic Science"
        ],
        "title": "Canadian Journal of Fisheries and Aquatic Sciences"
      },
      "publication_date": "2010-11-01",
      "selected": false,
      "title": "Individual transferable quotas and the \"tragedy of the commons\"",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=78149404014&origin=inward"
      ]
    },
    {
      "abstract": "This study presents how older Tibetan refugees have adapted to changing social and economic conditions in India. Participant observation and open-ended interview questions were used to explore life experiences of 14 older Tibetans living in India who participated in this study. Findings revealed that, after having to abandon familiar environments, these participants underwent harsh times in India but have adapted well. They have secured meaningful lives for themselves. Availability of children and institutional resources has proved beneficial at old age. Participants with children perceived that they were well cared for, which added to their satisfaction with present circumstances. However, those without children did not have any source of support and were dissatisfied. Religious activity was important for these participants. The ability to freely practice religion contributed to their satisfaction in exile. These findings are instructive for the treatment and acceptance of refugees throughout the world by contributing to the field of refugee aging and adaptation. \u00c2\u00a9 2010 The Author(s).",
      "authors": [
        "Wangmo, T.",
        "Teaster, P.B."
      ],
      "categories": null,
      "citations": 7,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1177/0733464809341468",
      "keywords": [
        "Tibetan diaspora",
        "old people\u00c4\u009d\u00e2\u0082\u00ac\u00e2\u0084\u00a2s homes",
        "caregiving",
        "adaptation",
        "older Tibetans"
      ],
      "number_of_pages": 21,
      "pages": "434-454",
      "publication": {
        "category": "Journal",
        "cite_score": 4.8,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "07334648",
        "publisher": "SAGE Publications Inc.",
        "sjr": 1.061,
        "snip": 1.516,
        "subject_areas": [
          "Geriatrics and Gerontology",
          "Gerontology"
        ],
        "title": "Journal of Applied Gerontology"
      },
      "publication_date": "2010-08-01",
      "selected": false,
      "title": "The bridge from then to now: Tibetan elders living in diaspora",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77955026344&origin=inward"
      ]
    },
    {
      "abstract": "Integrating traditional midwives (TMs) as labor support in cline-based care may be an ideal solution to improving maternity services in the Mexico and worldwide. We conducted interviews and focus groups with 65 TMs and 24 interviews with public health system personnel to assess the acceptability and challenges of this proposal. Both TMs and personnel perceive this new role as having professional benefits. Challenges include TMs' and clinic personnel's previous negative experience with one another and unfamiliarity with the doula role. Interactive trainings introducing the doula role and improving professional relations between TMs and personnel are necessary to assure success of this proposal.",
      "authors": [
        "Smid, Marcela",
        "Campero, Lourdes",
        "Cragin, Leslie",
        "Gonzalez Hernandez, Dolores",
        "Walker, Dilys"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1080/07399331003628438",
      "keywords": [],
      "number_of_pages": 378,
      "pages": "475-98",
      "publication": {
        "category": "Journal",
        "cite_score": 2.7,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "1096-4665",
        "publisher": "Taylor and Francis Ltd.",
        "sjr": 0.561,
        "snip": 0.802,
        "subject_areas": [
          "Health Professions  (all)"
        ],
        "title": "Health care for women international"
      },
      "publication_date": "2010-06-01",
      "selected": false,
      "title": "Bringing two worlds together: exploring the integration of traditional midwives as doulas in Mexican public hospitals.",
      "urls": []
    },
    {
      "abstract": "This contribution focuses on civilizing processes in the 20th century from an analysis of manners books in four Western countries since 1890. It connects to Norbert Elias\u00c3\u00a2\u00e2\u0082\u00ac\u00e2\u0084\u00a2s study by first describing how, in a long-term phase of formalizing manners and disciplining people, \u00c3\u00a2\u00e2\u0082\u00ac\u00c5\u0093dangerous\u00c3\u00a2\u00e2\u0082\u00ac? emotions such as those related to physical (including sexual) violence came to be controlled in increasingly automatic ways. Thus, a second-nature or conscience-dominated type of personality became dominant. The 20th century gave way to an informalization of manners and an emancipation of emotions: emotions that had been denied and repressed (re)gained access to consciousness and wider acceptance in social codes. Yet it was only after the 1950s that standards of self-control increasingly enabled people to admit to themselves and to others to have \u00c3\u00a2\u00e2\u0082\u00ac\u00c5\u0093dangerous\u00c3\u00a2\u00e2\u0082\u00ac? emotions without provoking shame, particularly the shame-fear of losing control and face. To the extent that it has become \u00c3\u00a2\u00e2\u0082\u00ac\u00c5\u0093natural\u00c3\u00a2\u00e2\u0082\u00ac? to perceive the pulls and pushes of both \u00c3\u00a2\u00e2\u0082\u00ac\u00c5\u0093first nature\u00c3\u00a2\u00e2\u0082\u00ac? and \u00c3\u00a2\u00e2\u0082\u00ac\u00c5\u0093second nature\u00c3\u00a2\u00e2\u0082\u00ac?, a \u00c3\u00a2\u00e2\u0082\u00ac\u00c5\u0093third nature\u00c3\u00a2\u00e2\u0082\u00ac? type of personality has been developing. Copyright 2010 Presses de Sc. Po. All rights reserved.",
      "authors": [
        "Wouters, C."
      ],
      "categories": null,
      "citations": 3,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.3917/vin.106.0161",
      "keywords": [],
      "number_of_pages": 15,
      "pages": "161-175",
      "publication": {
        "category": "Journal",
        "cite_score": 0.6,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "02941759",
        "publisher": "Presses de Sciences Po",
        "sjr": 0.106,
        "snip": 0.0,
        "subject_areas": [
          "History"
        ],
        "title": "Vingtieme Siecle: Revue d'Histoire"
      },
      "publication_date": "2010-05-21",
      "selected": false,
      "title": "How are civilizing processes prolonged? From \"second nature\" to \"third nature\"",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77952368118&origin=inward"
      ]
    },
    {
      "abstract": "The applications of neurophysiological therapy techniques range far and few in the realm of modern day medicine. However, the concept of electromagnetic stimulation, the basis for many noninvasive brain stimulation (NIBS) techniques today, has been of interest to the scientific community since the late nineteenth century. Recently, transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS), two noninvasive neurostimulation techniques, have begun to gain popularity and acceptance in the clinical neurophysiology, neurorehabilitaion, neurology, neuroscience, and psychiatry has spread widely, mostly in research applications, but increasingly with clinical aims in mind. These two neurophysiological techniques have proven to be valuable assets in not only the diagnosis, but also the treatment of many neurological disorders (post-stroke motor deficits, tinnitus, fibromyalgia, depression, epilepsy, autism, ageing and parkinson's disease). Its effects can be modulated by combination with pharmacological treatment that has undergone resurgence in recent years. In this review we discuss how these integrated technology like NIBS for evaluation in the clinical evidence to date and what mechanism it work for stroke rehabilitation particularly. Then, we will review the current situation of stroke rehabilitation in Iran and new hopes that NIBS could bring for clinicians and patients in this nationally prioritized field.",
      "authors": [
        "Bashir, S.",
        "Sikaroudi, H.",
        "Kazemi, R.",
        "Forough, B.",
        "Ekhtiari, H."
      ],
      "categories": null,
      "citations": 2,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": null,
      "keywords": [
        "Stroke",
        "Transcranial direct current stimulation (TDCS)",
        "Transcranial magnetic stimulation (TMS)"
      ],
      "number_of_pages": 9,
      "pages": "6-14",
      "publication": {
        "category": "Journal",
        "cite_score": 2.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "2008126X",
        "publisher": "Iran University of Medical Sciences",
        "sjr": 0.37,
        "snip": 0.504,
        "subject_areas": [
          "Neurology (clinical)",
          "Cellular and Molecular Neuroscience"
        ],
        "title": "Basic and Clinical Neuroscience"
      },
      "publication_date": "2010-01-01",
      "selected": false,
      "title": "Integrated technologies like noninvasive brain stimulation (nibs) for stroke rehabilitation, new hopes for patients, neuroscientists, and clinicians in iran",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84890060446&origin=inward"
      ]
    },
    {
      "abstract": "One of the main concerns of the Common Fisheries Policy (CFP) lies in guaranteeing consistency among the different implemented actions. The main concern is establishing a relationship between the levels of compliance with the Multi-annual Guidance Programme (MAGP), the adoption of total allowable catches (TACs), and the levels of compliance with rules by producers. This paper concludes that the percentage of non-compliance with the CFP is very high. Thus, it is very difficult to combine the aims of biological, economic and social sustainability with the references to the present status of resources and the situation of demand and prices of fishing products. \u00c2\u00a9 2009 Elsevier Ltd. All rights reserved.",
      "authors": [
        "Gonz\u00c3\u00a1lez Laxe, F."
      ],
      "categories": null,
      "citations": 14,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1016/j.marpol.2009.06.003",
      "keywords": [
        "Common Fisheries Policy",
        "Governance",
        "European Union",
        "Policy arrangements",
        "Coherence",
        "Fisheries management"
      ],
      "number_of_pages": 7,
      "pages": "182-188",
      "publication": {
        "category": "Journal",
        "cite_score": 7.0,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "0308597X",
        "publisher": "Elsevier Ltd.",
        "sjr": 1.034,
        "snip": 1.352,
        "subject_areas": [
          "Law",
          "Economics and Econometrics",
          "Environmental Science (all)",
          "Aquatic Science",
          "Management, Monitoring, Policy and Law"
        ],
        "title": "Marine Policy"
      },
      "publication_date": "2010-01-01",
      "selected": false,
      "title": "Dysfunctions in common fishing regulations",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70349619193&origin=inward"
      ]
    },
    {
      "abstract": "The objective of this article is to describe the case of a twelve-year-old girl with Type-1 Diabetes, who had a history of hospitalisation due to Diabetes Ketoacidosis (DKA) and had been placed into the child protection register. The report advocates an Understanding of the Social Ecological Model (Bronfenbrenner, 1976) in relation to assessing poor metabolic control, and examines the use of Multisystemic Therapy (MST) in treatment adherence. The assessment explores the beliefs within the child\u00c4\u009d\u00e2\u0082\u00ac\u00e2\u0084\u00a2s systems and subsystems. Formulating from a Systemic Perspective allowed for integrated Cognitive Behavioural Therapy, Family Therapy and Systems Oriented intervention applied to the Microsystems\u00c4\u009d\u00e2\u0082\u00ac\u00e2\u0084\u00a2 beliefs. After treatment and at follow-up the child was removed from the Child Protection register and has remained to date without admission to hospital experiencing DKA. MST has the possibility of offering a new perspective for treatment in complex cases of children with diabetes and severe treatment adherence problems.",
      "authors": [
        "Martin, C.",
        "Southall, A.",
        "Liveley, K.",
        "Shea, E.",
        "Whitehead, K."
      ],
      "categories": null,
      "citations": 5,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1177/1534650109345155",
      "keywords": [
        "DKA",
        "Multisystemic Therapy",
        "Social ecological model",
        "Diabetes",
        "Treatment adherence"
      ],
      "number_of_pages": 17,
      "pages": "366-382",
      "publication": {
        "category": "Journal",
        "cite_score": 1.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "15346501",
        "publisher": "SAGE Publications Inc.",
        "sjr": 0.251,
        "snip": 0.359,
        "subject_areas": [
          "Psychiatry and Mental Health",
          "Clinical Psychology"
        ],
        "title": "Clinical Case Studies"
      },
      "publication_date": "2009-10-01",
      "selected": false,
      "title": "Multisystemic Therapy applied to the assessment and treatment of poorly controlled type-1 diabetes: A case study in the U.K. national health service",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70349556788&origin=inward"
      ]
    },
    {
      "abstract": "This paper explores the challenges and opportunities associated with the evaluation of treatments arising from traditional medical systems (TMS). Globalization and popular consumer-and industry-driven market forces contribute to the spread of traditional treatments, techniques and technologies, but do not necessarily ensure their usefulness or safety. The international scientific community is obliged to evaluate the safety and efficacy of these treatments because of their potential impact on global public health. Clinical evaluations of traditional treatments, however, have complex methodological and practical challenges, depending on the goals of the research and the audience for the results (country of origin; or new host countries and new patient populations). To address these challenges, the authors offer the following recommendations to identify and prioritize treatments to study and how to design study protocols. Evaluations of traditional treatments are best addressed first by collaborative, international, pragmatic studies. Protocols for observational, prospective, pragmatic pilot study (randomized and controlled, when feasible) should be designed collaboratively and executed simultaneously in the culture of origin and in new contexts. This, in turn, could determine the acceptability, usefulness and feasibility of larger randomized controlled trials (RCTs). International multicentre RCTs would have the potential benefits of evaluating safety and effectiveness and also assessing the transferability of a traditional treatment across social and cultural contexts. \u00c2\u00a9 2006 Elsevier Ltd. All rights reserved.",
      "authors": [
        "Cardini, Francesco",
        "Wade, Christine",
        "Regalia, Anna Laura",
        "Gui, Suiqi",
        "Li, Wang",
        "Raschetti, Roberto",
        "Kronenberg, Fredi"
      ],
      "categories": null,
      "citations": 38,
      "comments": null,
      "databases": [
        "Scopus",
        "PubMed"
      ],
      "doi": "10.1016/j.ctim.2006.07.003",
      "keywords": [
        "Methods",
        "Traditional medicine",
        "Clinical research",
        "Priorities",
        "Pragmatic trials"
      ],
      "number_of_pages": 276,
      "pages": "282-287",
      "publication": {
        "category": "Journal",
        "cite_score": 7.2,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "0965-2299",
        "publisher": "Churchill Livingstone",
        "sjr": 0.652,
        "snip": 1.215,
        "subject_areas": [
          "Complementary and Alternative Medicine",
          "Advanced and Specialized Nursing",
          "Complementary and Manual Therapy"
        ],
        "title": "Complementary therapies in medicine"
      },
      "publication_date": "2006-08-28",
      "selected": false,
      "title": "Clinical research in traditional medicine: priorities and methods.",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33750715157&origin=inward"
      ]
    },
    {
      "abstract": "The label 'teachable moment' (TM) has been used to describe naturally occurring health events thought to motivate individuals to spontaneously adopt risk-reducing health behaviors. This manuscript summarizes the evidence of TMs for smoking cessation, and makes recommendations for conceptual and methodological refinements to improve the next generation of related research. TM studies were identified for the following event categories: office visits, notification of abnormal test results, pregnancy, hospitalization and disease diagnosis. Cessation rates associated with pregnancy, hospitalization and disease diagnosis were high (10-60 and 15-78%, respectively), whereas rates for clinic visits and abnormal test results were consistently lower (2-10 and 7-21%, respectively). Drawing from accepted conceptual models, a TM heuristic is outlined that suggests three domains underlie whether a cueing event is significant enough to be a TM for smoking cessation: the extent to which the event (1) increases perceptions of personal risk and outcome expectancies, (2) prompts strong affective or emotional responses, and (3) redefines self-concept or social role. Research in TMs could be improved by giving greater attention to assessment of conceptually grounded cognitive and emotional variables, appropriately timed assessment and intervention, and inclusion of appropriate target and comparison samples.",
      "authors": [
        "McBride, C M",
        "Emmons, K M",
        "Lipkus, I M"
      ],
      "categories": null,
      "citations": null,
      "comments": null,
      "databases": [
        "PubMed"
      ],
      "doi": "10.1093/her/18.2.156",
      "keywords": [],
      "number_of_pages": 87,
      "pages": "156-70",
      "publication": {
        "category": "Journal",
        "cite_score": 3.4,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "0268-1153",
        "publisher": "Oxford University Press",
        "sjr": 0.61,
        "snip": 0.841,
        "subject_areas": [
          "Public Health, Environmental and Occupational Health",
          "Education"
        ],
        "title": "Health education research"
      },
      "publication_date": "2003-04-01",
      "selected": false,
      "title": "Understanding the potential of teachable moments: the case of smoking cessation.",
      "urls": []
    },
    {
      "abstract": "In this paper we examine the design of the first wireless systems as infrastructure making. An infrastructure is fundamentally a relational concept. Accordingly, we shall analyze how relationships between entrepreneurs, system builders and regulators were organized so that some early wireless systems achieved a high momentum. In high momentum, a technological system seems to drive toward a specific direction with a certain autonomy and this demands that technological, economic, political and social challenges be integrated effectively into the overall design. Such an integration can only succeed through an effective mobilization and coordination of both systems builders' and other stakeholders' (entrepreneurs, and regulators in particular) concerns. We analyze five cases of building first-generation wireless solutions and examine to what extent specific relationships between key actors influenced whether these systems did achieve a high momentum. Our analysis shows that managing critical relationships with regulators, correct timing, and effective and continuous meshing of both entrepreneurs' and technologists' concerns were typical for systems that achieved high momentum. In all successful cases, the meshing and associated institutional response demanded the creation of an open standard. These include both AMPS/TACS family of standards, and especially the Nordic NMT standard. \u00c2\u00a9 2002 Published by Elsevier Science Ltd.",
      "authors": [
        "Lyytinen, K.",
        "Fomin, V.V."
      ],
      "categories": null,
      "citations": 51,
      "comments": null,
      "databases": [
        "Scopus"
      ],
      "doi": "10.1016/S0308-5961(02)00006-X",
      "keywords": [
        "Standards",
        "Innovation and diffusion factors",
        "Complex technological systems",
        "Process study",
        "First-generation wireless"
      ],
      "number_of_pages": 22,
      "pages": "149-170",
      "publication": {
        "category": "Journal",
        "cite_score": 8.1,
        "is_potentially_predatory": false,
        "isbn": null,
        "issn": "03085961",
        "publisher": "Elsevier Ltd.",
        "sjr": 1.192,
        "snip": 1.947,
        "subject_areas": [
          "Management, Monitoring, Policy and Law",
          "Library and Information Sciences",
          "Management Information Systems",
          "Information Systems",
          "Economics and Econometrics",
          "Communication"
        ],
        "title": "Telecommunications Policy"
      },
      "publication_date": "2002-04-01",
      "selected": false,
      "title": "Achieving high momentum in the evolution of wireless infrastructures: The battle over the 1 G solutions",
      "urls": [
        "https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0036537352&origin=inward"
      ]
    }
  ],
  "processed_at": "2024-01-10 03:52:25",
  "publication_types": null,
  "query": "([neurofeedback] OR [neurostimulation] OR [TMS] OR [tDCS] OR [tACS]) AND ([social] OR [autism] OR [attachment]) AND ([acceptability] OR [feasibility] OR [acceptance] OR [compliance] OR [adherence])",
  "since": "2000-01-01",
  "until": "2023-12-31"
}