{"text_format":"2","workbook":"xlsx","n_sheets":22,"sheets":["Figure 1a","Figure 1b","Figure 1c","Figure 1d","Figure 2a","Figure 2b","Figure 4a","Figure 4b","Figure 4c","Figure 4d","Figure 4e","Figure 6b","Figure 7a","Figure 7b","Figure 7c","Figure 7d","Figure 7e","Suppl Fig 9b","Suppl Fig 10b","Suppl Fig 11","Suppl Fig 12a","Suppl Fig 12b"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":0,"defined_names":0,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900"}

{"sheet":"Figure 1a","index":0,"n_rows":37,"n_cols":12,"rows_kept":37,"cut":false,"hidden":false,"merged":[[1,0,1,2],[1,3,1,5]]}
["Plotted data (average of 3 experiments) "]
["rTg4510 (8)",null,null,"rT2T2 (10)"]
["Mean","Mean Error","N","Mean","Mean Error","N"]
[0.99128400000000005,4.5366999999999998E-2,3,1.5347299999999999,5.6133000000000002E-2,3]
[1.2826169999999999,9.9366999999999997E-2,3,1.1769480000000001,6.1866999999999998E-2,3]
[1.5920890000000001,0.12906699999999999,3,1.1956610000000001,0.1308,3]
[0.98018899999999998,6.6267000000000006E-2,3,1.7890550000000001,8.8867000000000002E-2,3]
[1.5128470000000001,8.4432999999999994E-2,3,1.269401,7.6533000000000004E-2,3]
[0.76801900000000001,3.9566999999999998E-2,3,0.981962,6.6500000000000004E-2,3]
[0.83897600000000006,4.1766999999999999E-2,3,0.85735099999999997,4.1333000000000002E-2,3]
[0.80273000000000005,3.9366999999999999E-2,3,1.163583,6.6299999999999998E-2,3]
[null,null,null,0.87054399999999998,5.1033000000000002E-2,3]
[null,null,null,1.1162000000000001,2.76E-2,3]
[]
[]
["Raw data from each experiment"]
[null,"Experiment 1",null,null,null,"Experiment 2",null,null,null,"Experiment 3"]
[null,"rT2/T2","Tau:HPRT","Error (from triplicates)",null,"rT2/T2","Tau:HPRT","Error (from triplicates)",null,"rT2/T2","Tau:HPRT","Error (from triplicates)"]
[null,null,1.7107540173053151,8.7400000000000005E-2,null,null,1.2378684807256237,0.04,null,null,1.6555671175858482,4.1000000000000002E-2]
[null,null,1.2332685855553593,0.1232,null,null,1.0553287981859409,2.4299999999999999E-2,null,null,1.2422476586888658,3.8100000000000002E-2]
[null,null,1.0397315910294895,2.7799999999999998E-2,null,null,1.3229024943310659,0.28799999999999998,null,null,1.2243496357960459,7.6600000000000001E-2]
[null,null,1.0328447819177113,3.9300000000000002E-2,null,null,0.67823129251700676,2.1499999999999998E-2,null,null,0.86097814776274717,6.3200000000000006E-2]
[null,null,1.3676496556595443,0.13750000000000001,null,null,1.1024943310657598,1.0999999999999999E-2,null,null,1.0206035379812695,5.04E-2]
[null,null,0.96609570898816888,2.9899999999999999E-2,null,null,0.77165532879818588,5.4699999999999999E-2,null,null,0.87388137356919882,6.8500000000000005E-2]
[null,null,1.8419505023278608,0.10630000000000001,null,null,1.6962714034245481,7.6300000000000007E-2,null,null,1.8289419514203376,8.4000000000000005E-2]
[null,null,1.4268561627052194,7.0999999999999994E-2,null,null,1.0384061449831974,3.6999999999999998E-2,null,null,1.3429394812680115,0.1216]
[null,null,1.0448419505023279,7.85E-2,null,null,0.88478156505040795,6.7500000000000004E-2,null,null,1.0162618361465625,5.3499999999999999E-2]
[null,null,1.1516785101690761,1.21E-2,null,null,1.1497839654344695,3.5799999999999998E-2,null,null,1.0471387402223138,3.49E-2]
[null,"rTg4510","Tau:HPRT","Error (from triplicates)",null,"rTg4510","Tau:HPRT","Error (from triplicates)",null,"rTg4510","Tau:HPRT","Error (from triplicates)"]
[null,null,1.0711636941550415,6.4399999999999999E-2,null,null,0.89977324263038549,1.49E-2,null,null,1.0029136316337148,5.6800000000000003E-2]
[null,null,1.9230090058272999,0.21149999999999999,null,null,1.247845804988662,5.6899999999999999E-2,null,null,1.6054110301768991,0.1188]
[null,null,1.0775207487197598,5.6099999999999997E-2,null,null,0.93401360544217682,8.6099999999999996E-2,null,null,0.92903225806451617,5.6599999999999998E-2]
[null,null,1.900052975454706,8.5500000000000007E-2,null,null,1.258049886621315,4.4699999999999997E-2,null,null,1.3804370447450574,0.1231]
[null,null,1.3357020338152414,0.1028,null,null,1.3256521043366938,7.85E-2,null,null,1.1864965006175381,0.1168]
[null,null,0.82675814751286436,4.2599999999999999E-2,null,null,0.78812610017602813,4.3400000000000001E-2,null,null,0.68917249897076982,3.27E-2]
[null,null,0.85983827493261444,5.16E-2,null,null,0.79500720115218437,3.2800000000000003E-2,null,null,0.86208316179497735,4.0899999999999999E-2]
[null,null,0.83802989463366828,2.1399999999999999E-2,null,null,0.8326132181148983,4.1599999999999998E-2,null,null,0.73754631535611359,5.5100000000000003E-2]

{"sheet":"Figure 1b","index":1,"n_rows":12,"n_cols":3,"rows_kept":12,"cut":false,"hidden":false,"merged":[]}
["tTA (6)","rTg4510 (8)","rT2/T2 (11)"]
[6.9761000000000004E-2,0.88067700000000004,1.3677630000000001]
[0.133438,1.4459310000000001,1.391467]
[7.4460999999999999E-2,1.035434,1.325947]
[7.9804E-2,0.73173900000000003,1.086635]
[6.1697000000000002E-2,0.40359,1.737088]
[0.117407,1.3178080000000001,2.1057459999999999]
[null,2.100104,1.7171639999999999]
[null,0.53513999999999995,0.99201300000000003]
[null,null,1.3994420000000001]
[null,null,1.3812789999999999]
[null,null,2.1828349999999999]

{"sheet":"Figure 1c","index":2,"n_rows":21,"n_cols":9,"rows_kept":21,"cut":false,"hidden":false,"merged":[[8,1,8,2],[8,4,8,5],[8,7,8,8],[1,2,1,4],[1,5,1,7]]}
["Plotted data"]
[null,"Age (months)","rT2/T2",null,null,"rTg4510"]
[null,null,"Mean","SD","N","Mean","SD","N"]
[null,2,0.4506,2.3230000000000001E-2,10,0.45250000000000001,2.163E-2,11]
[null,5,0.47070000000000001,3.1530000000000002E-2,3,0.442,1.9609999999999999E-2,4]
[null,7,0.46429999999999999,2.043E-2,4,0.42,1.6629999999999999E-2,4]
[]
["Raw data"]
[null,"2 months",null,null,"5 months",null,null,"7 months"]
[null,"rT2/T2 2M (10)","rTg4510 2M (11)",null,"rT2/T2 5M (3)","rTg4510  5M (4)",null,"rT2/T2 7M (4)","rTg4510 7M (4)"]
[null,0.45400000000000001,0.45100000000000001,null,0.505,0.47099999999999997,null,0.46600000000000003,0.41299999999999998]
[null,0.44800000000000001,0.46200000000000002,null,0.443,0.43,null,0.45800000000000002,0.441]
[null,0.45300000000000001,0.44900000000000001,null,0.46400000000000002,0.437,null,0.442,0.40200000000000002]
[null,0.42,0.438,null,null,0.43,null,0.49099999999999999,0.42399999999999999]
[null,0.47099999999999997,0.439]
[null,0.45800000000000002,0.42199999999999999]
[null,0.45900000000000002,0.433]
[null,0.48299999999999998,0.47099999999999997]
[null,0.45700000000000002,0.496]
[null,0.40300000000000002,0.441]
[null,null,0.47499999999999998]

{"sheet":"Figure 1d","index":3,"n_rows":20,"n_cols":9,"rows_kept":20,"cut":false,"hidden":false,"merged":[[1,2,1,4],[1,5,1,7],[8,1,8,2],[8,4,8,5],[8,7,8,8]]}
["Plotted data"]
[null,"Age (months)","rT2/T2",null,null,"rTg4510"]
[null,null,"Mean","SD","N","Mean","SD","N"]
[null,2,0.154,8.6020000000000003E-3,10,0.15290000000000001,9.8799999999999999E-3,9]
[null,5,0.152,5.2919999999999998E-3,4,0.14680000000000001,4.9919999999999999E-3,4]
[null,7,0.1578,6.0210000000000003E-3,4,0.13100000000000001,2E-3,3]
[]
["Raw data"]
[null,"2 months",null,null,"5 months",null,null,"7 months"]
[null,"rT2/T2 2M (10)","rTg4510 2M (9)",null,"rT2/T2 5M (3)","rTg4510 5M (4)",null,"rT2/T2 7M (4)","rTg4510 7M (3)"]
[null,0.14799999999999999,0.161,null,0.158,0.15,null,0.152,0.129]
[null,0.154,0.15,null,0.15,0.151,null,0.155,0.13100000000000001]
[null,0.16500000000000001,0.13100000000000001,null,0.14799999999999999,0.14000000000000001,null,0.158,0.13300000000000001]
[null,0.13700000000000001,0.159,null,null,0.14599999999999999,null,0.16600000000000001]
[null,0.16300000000000001,0.14899999999999999]
[null,0.157,0.159]
[null,0.153,0.159]
[null,0.16200000000000001,0.14699999999999999]
[null,0.155,0.161]
[null,0.14599999999999999]

{"sheet":"Figure 2a","index":4,"n_rows":21,"n_cols":73,"rows_kept":21,"cut":false,"hidden":false,"merged":[[0,1,0,15],[0,16,0,61],[0,62,0,72]]}
["Age (months)","rT2/T2",{"$nulls":14},"rT2",{"$nulls":45},"rTg4510 N2"]
[1,{"$nulls":15},0.13800000000000001,0.152,0.155,0.158,0.154,0.15,0.152,0.157,0.156,0.159,0.16700000000000001,0.16400000000000001]
[2,0.14799999999999999,0.157,0.153,0.16200000000000001,0.154,0.16500000000000001,0.13700000000000001,0.16300000000000001,0.155,0.155,0.14599999999999999,0.153,0.14799999999999999,0.14599999999999999,0.151,0.183,0.18,0.157,0.157,0.16,0.15,0.17,0.16600000000000001,0.17699999999999999,0.17599999999999999,0.17100000000000001,0.16300000000000001,0.17299999999999999,0.17299999999999999,0.17799999999999999,0.18099999999999999,0.16500000000000001,0.16800000000000001,0.16300000000000001,0.187,0.193,0.159,0.161,0.161,0.156,0.16200000000000001,0.17100000000000001,0.16400000000000001,0.16400000000000001,0.16900000000000001,0.14099999999999999,0.157,0.17199999999999999,0.16500000000000001,0.159,0.16600000000000001,0.16,0.151,0.154,0.156,0.161,0.16400000000000001,0.16900000000000001,0.16200000000000001,0.16600000000000001,0.16,0.13100000000000001,0.14899999999999999,0.159,0.14699999999999999,0.15,0.159,0.159,0.161,0.161]
[3,{"$nulls":15},0.16700000000000001]
[4,{"$nulls":15},0.157,0.158,0.17,0.157,0.159,{"$nulls":41},0.159]
[5,0.15,0.14799999999999999,0.128,0.158,{"$nulls":11},0.17899999999999999,0.17199999999999999,0.16200000000000001,0.17199999999999999,0.14799999999999999,0.16900000000000001,0.17599999999999999,0.17599999999999999,{"$nulls":38},0.14000000000000001,0.14599999999999999,0.15,0.151]
[6,0.158,0.159]
[7,0.16600000000000001,0.152,0.14699999999999999,0.155,0.189,{"$nulls":56},0.122,0.123,0.13,0.14000000000000001,0.153,0.129,0.13300000000000001,0.13100000000000001,0.123,0.13800000000000001]
[8,0.156,0.14499999999999999,0.16400000000000001,0.14899999999999999,{"$nulls":11},0.156,0.14000000000000001,0.17399999999999999,0.17299999999999999,0.17399999999999999,0.192,0.11700000000000001,0.182,0.18,{"$nulls":37},0.127,0.13500000000000001]
[9,0.17299999999999999,0.17799999999999999,0.158,0.153,0.14399999999999999,0.161,0.151,0.13,{"$nulls":53},9.6000000000000002E-2,0.126,0.13300000000000001,0.13400000000000001,0.13600000000000001,0.16,0.10299999999999999,0.106,0.106,0.109,0.128]
[10,0.13100000000000001]
[11]
[12,{"$nulls":15},0.16500000000000001,0.16200000000000001,0.159,0.158,0.155,0.153]
[13,8.2000000000000003E-2,9.7000000000000003E-2,8.7999999999999995E-2]
[14]
[15,8.6999999999999994E-2,9.6000000000000002E-2,{"$nulls":13},0.14499999999999999,0.17,0.14399999999999999]
[16,{"$nulls":61},8.2000000000000003E-2]
[17]
[18,{"$nulls":15},0.122,0.13400000000000001,0.14000000000000001,0.16500000000000001]
[19]
[20]

{"sheet":"Figure 2b","index":5,"n_rows":29,"n_cols":207,"rows_kept":29,"cut":false,"hidden":false,"merged":[[0,1,0,130],[0,131,0,141],[0,142,0,151],[0,152,0,206]]}
["Age (months)","rTg4510 F1",{"$nulls":129},"rTg4510 N2",{"$nulls":10},"rT2/T2",{"$nulls":9},"rT2"]
[1,0.38200000000000001,0.42699999999999999,0.41699999999999998,0.43,{"$nulls":147},0.38600000000000001,0.39300000000000002,0.41899999999999998,0.42,0.42099999999999999,0.42199999999999999,0.42799999999999999,0.45100000000000001,0.45,0.45,0.45900000000000002,0.441]
[2,0.443,0.46700000000000003,0.46300000000000002,0.44900000000000001,0.443,0.46600000000000003,0.46700000000000003,0.46,0.39300000000000002,0.41899999999999998,0.433,0.437,0.46600000000000003,0.45400000000000001,0.42499999999999999,0.43099999999999999,0.41,0.44700000000000001,0.46100000000000002,0.47,0.44500000000000001,0.435,0.433,0.434,0.443,0.45400000000000001,0.47799999999999998,0.47699999999999998,0.46800000000000003,0.41699999999999998,0.46700000000000003,0.47899999999999998,0.45400000000000001,0.434,{"$nulls":96},0.45100000000000001,0.46200000000000002,0.44900000000000001,0.438,0.439,0.42199999999999999,0.433,0.47099999999999997,0.496,0.441,0.47499999999999998,0.45400000000000001,0.44800000000000001,0.45300000000000001,0.42,0.47099999999999997,0.45800000000000002,0.45900000000000002,0.48299999999999998,0.45700000000000002,0.40300000000000002,0.47,0.497,0.45800000000000002,0.49199999999999999,0.47199999999999998,0.47099999999999997,0.48699999999999999,0.48,0.48799999999999999,0.5,0.49099999999999999,0.5,0.49,0.47699999999999998,0.49099999999999999,0.496,0.45500000000000002,0.46300000000000002,0.49,0.499,0.50600000000000001,0.47099999999999997,0.44700000000000001,0.46300000000000002,0.45,0.46400000000000002,0.46500000000000002,0.47,0.47099999999999997,0.47099999999999997,0.47199999999999998,0.45900000000000002,0.46200000000000002,0.46899999999999997,0.47,0.50900000000000001,0.47399999999999998,0.47399999999999998,0.46400000000000002,0.46899999999999997,0.46,0.44,0.505,0.47799999999999998,0.49099999999999999,0.51600000000000001,0.47299999999999998,0.46899999999999997,0.48,0.49299999999999999,0.501,0.48499999999999999,0.46300000000000002,0.48399999999999999,0.495]
[3,0.438,0.45700000000000002,0.45200000000000001,0.45300000000000001,0.47599999999999998,0.44800000000000001,0.45600000000000002,0.442,0.46200000000000002,0.42699999999999999,0.44900000000000001,0.47199999999999998,0.46200000000000002,0.45300000000000001,0.433,0.441,0.48499999999999999,0.44700000000000001,0.45900000000000002,0.44600000000000001,0.438,0.45700000000000002,0.45400000000000001,0.42699999999999999,0.45500000000000002,0.439,0.46800000000000003,0.46400000000000002,0.46100000000000002,0.41899999999999998,0.44500000000000001,0.46700000000000003,0.44,0.44800000000000001,0.45700000000000002,0.42699999999999999,0.45400000000000001,0.48699999999999999,0.46100000000000002,0.44600000000000001,0.44700000000000001,0.44500000000000001,0.48,0.50700000000000001,0.502,0.44400000000000001,0.46,0.46400000000000002,0.45900000000000002,0.51500000000000001,0.439,0.438,0.48099999999999998,0.47799999999999998,0.46800000000000003,0.46600000000000003,0.47099999999999997,0.46400000000000002,0.49099999999999999,0.49299999999999999,0.46800000000000003,0.498,0.48399999999999999,0.48,0.48499999999999999,0.49399999999999999,0.48899999999999999,0.48499999999999999,0.46500000000000002,0.46400000000000002,0.47299999999999998,0.503,0.49399999999999999,0.47499999999999998,0.495,0.438,0.47499999999999998,0.49,0.47499999999999998,0.46300000000000002,0.45900000000000002,0.47,0.46500000000000002,0.46100000000000002,0.46700000000000003,0.49,0.45800000000000002,0.45700000000000002,0.48399999999999999,0.5,0.49399999999999999,0.46400000000000002,{"$nulls":59},0.46700000000000003,0.499,0.47299999999999998,0.48299999999999998,0.47899999999999998]
[4,0.498,0.48099999999999998,0.502,0.47499999999999998,0.45900000000000002,0.48499999999999999,0.49099999999999999,0.46300000000000002,0.46300000000000002,0.48,0.46100000000000002,0.47,0.47899999999999998,0.44800000000000001,0.47499999999999998,0.42499999999999999,0.44,0.42,0.50600000000000001,0.46899999999999997,0.46,0.47199999999999998,0.45400000000000001,0.45300000000000001,0.45300000000000001,0.47099999999999997,0.47099999999999997,0.503,0.45500000000000002,{"$nulls":122},0.46700000000000003,0.47,0.48599999999999999,0.497,0.47499999999999998]
[5,0.48399999999999999,0.48299999999999998,0.47699999999999998,0.48699999999999999,0.504,0.47499999999999998,0.48,0.48799999999999999,0.50900000000000001,0.47599999999999998,0.47,0.48499999999999999,0.45300000000000001,0.441,0.49399999999999999,0.45700000000000002,0.48799999999999999,0.45,0.44400000000000001,0.46899999999999997,0.434,0.45,0.44600000000000001,0.42599999999999999,0.46600000000000003,0.46600000000000003,0.441,0.436,0.46500000000000002,0.49399999999999999,0.39700000000000002,0.47799999999999998,0.45500000000000002,0.47899999999999998,0.51,0.48799999999999999,0.50800000000000001,0.48699999999999999,0.50700000000000001,0.48599999999999999,0.47499999999999998,0.46500000000000002,0.48099999999999998,0.505,0.50800000000000001,0.45300000000000001,0.46700000000000003,0.45800000000000002,0.45800000000000002,0.48799999999999999,0.48799999999999999,0.45500000000000002,0.436,0.5,0.47599999999999998,0.48799999999999999,0.496,0.49099999999999999,0.47299999999999998,0.46800000000000003,0.48399999999999999,0.48099999999999998,0.45200000000000001,0.41899999999999998,0.495,0.42399999999999999,0.42699999999999999,0.46100000000000002,0.47899999999999998,0.433,0.47299999999999998,0.42899999999999999,0.48599999999999999,0.441,0.46800000000000003,0.46899999999999997,0.42099999999999999,0.39800000000000002,0.39500000000000002,0.435,0.42299999999999999,0.496,0.47399999999999998,0.45200000000000001,0.48599999999999999,0.47699999999999998,0.41699999999999998,0.45200000000000001,0.434,0.47499999999999998,0.44500000000000001,0.42499999999999999,0.44,0.502,0.41499999999999998,0.46800000000000003,0.49199999999999999,0.46600000000000003,0.46700000000000003,0.45300000000000001,0.41799999999999998,0.45,0.46300000000000002,0.45300000000000001,0.47499999999999998,0.45800000000000002,0.436,0.46100000000000002,0.435,0.41099999999999998,0.46700000000000003,0.437,0.48,0.45400000000000001,0.46,0.45100000000000001,0.48499999999999999,0.47499999999999998,0.48699999999999999,0.45700000000000002,0.46100000000000002,0.41899999999999998,0.45500000000000002,0.46200000000000002,0.44700000000000001,0.45700000000000002,0.44900000000000001,0.47899999999999998,0.47499999999999998,0.46400000000000002,0.47099999999999997,0.43,0.437,0.43,{"$nulls":7},0.505,0.443,0.46400000000000002,{"$nulls":7},0.32700000000000001,0.36199999999999999,0.502,0.50900000000000001,0.44900000000000001,0.47799999999999998,0.505,0.48199999999999998,0.49399999999999999,0.51500000000000001,0.51800000000000002]
[6,0.46700000000000003,0.46300000000000002,0.44800000000000001,0.46300000000000002,0.46,0.44800000000000001,0.47,0.46800000000000003,0.45800000000000002,0.46100000000000002,0.47899999999999998,0.52500000000000002,0.48299999999999998,0.53400000000000003,0.48299999999999998,0.45800000000000002,0.55300000000000005,0.45,0.43,0.48899999999999999,0.46500000000000002,0.52800000000000002,0.42599999999999999,0.41799999999999998,0.442,0.46200000000000002,0.46800000000000003,0.47899999999999998,0.51500000000000001,0.47699999999999998,0.437,0.49,0.47499999999999998,0.47399999999999998,0.47399999999999998,0.46400000000000002,0.51300000000000001,0.51700000000000002,0.50900000000000001,0.51900000000000002,0.495,0.48399999999999999,0.53500000000000003,0.48699999999999999,0.47599999999999998,0.48,0.51300000000000001,0.51,0.52900000000000003,0.53,0.505,0.48399999999999999,0.49099999999999999,0.53800000000000003,0.50900000000000001,0.52,0.51800000000000002,0.503,0.5,0.51400000000000001,0.48399999999999999,0.47,0.49099999999999999,0.49099999999999999,0.44900000000000001,0.439,0.47499999999999998,0.48199999999999998]
[7,0.45,0.47399999999999998,0.49299999999999999,0.45,0.46500000000000002,0.46800000000000003,0.44600000000000001,0.54100000000000004,0.48499999999999999,0.504,0.47699999999999998,0.48599999999999999,0.48299999999999998,0.49399999999999999,0.44800000000000001,0.49099999999999999,0.48799999999999999,0.44400000000000001,0.49,0.47399999999999998,0.438,0.45600000000000002,0.44900000000000001,0.48299999999999998,0.47899999999999998,0.44700000000000001,0.46200000000000002,0.48199999999999998,0.45200000000000001,0.496,0.41799999999999998,0.39600000000000002,0.34799999999999998,0.42699999999999999,0.42799999999999999,{"$nulls":95},0.41299999999999998,0.441,0.40200000000000002,0.42399999999999999,{"$nulls":7},0.46600000000000003,0.45800000000000002,0.442,0.49099999999999999]
[8,0.442,0.45800000000000002,0.432,0.442,0.443,0.442,0.317,0.30199999999999999,0.29499999999999998,0.318,0.442,0.42599999999999999,0.432,0.41499999999999998,0.45700000000000002,0.42799999999999999,0.41499999999999998,0.42899999999999999,0.432,0.39300000000000002,0.42399999999999999,{"$nulls":130},0.49199999999999999,0.496,0.495,0.53400000000000003,0.53500000000000003,0.50700000000000001,0.51100000000000001,0.44400000000000001,0.52200000000000002]
[9,0.46600000000000003,0.45500000000000002,0.45700000000000002,0.438,0.44500000000000001,0.42599999999999999,0.42699999999999999,0.44700000000000001,0.46300000000000002,0.504,0.48799999999999999,{"$nulls":119},0.43099999999999999,0.39800000000000002,0.35899999999999999,0.46400000000000002,0.441,0.42399999999999999,0.34799999999999998,0.38900000000000001,0.378,0.38300000000000001,0.43099999999999999,0.45700000000000002,0.439,0.436,0.48099999999999998,0.52200000000000002,0.53900000000000003,0.433,0.45200000000000001]
[10,0.46100000000000002,0.47499999999999998,0.501,0.432,0.443,0.438,0.439,0.47699999999999998,0.49399999999999999,0.46600000000000003,0.46700000000000003,0.42199999999999999,0.45300000000000001,0.435,0.47699999999999998,0.437,0.438,0.41599999999999998,0.441,0.35399999999999998,0.36499999999999999,0.36499999999999999,0.35,0.41,0.39300000000000002,0.36,0.42699999999999999,0.43,0.34399999999999997,0.42199999999999999,0.40300000000000002,0.436,0.33900000000000002,0.34,0.40799999999999997,0.36699999999999999,0.47599999999999998,0.47199999999999998,0.45100000000000001,0.46600000000000003,0.438,0.46700000000000003,0.373,0.46,0.436,{"$nulls":96},0.45,0.433]
[11,0.44600000000000001,0.40699999999999997]
[12,0.39300000000000002,0.40100000000000002,0.41799999999999998,0.42099999999999999,0.42399999999999999,0.36499999999999999,0.39200000000000002,0.42699999999999999,0.41699999999999998,{"$nulls":142},0.50900000000000001,0.51,0.52600000000000002,0.48399999999999999,0.48799999999999999,0.5]
[13,0.40899999999999997,0.36,{"$nulls":139},0.32,0.32100000000000001,0.34300000000000003]
[14,0.35099999999999998,0.33900000000000002,0.33600000000000002,0.38900000000000001,0.32300000000000001,0.34599999999999997,0.36899999999999999,0.33400000000000002,0.41899999999999998,0.42899999999999999,0.40200000000000002,0.41199999999999998,0.434,0.371,0.38900000000000001,{"$nulls":115},0.36099999999999999]
[15,{"$nulls":141},0.32100000000000001,0.33600000000000002,{"$nulls":8},0.47799999999999998,0.48,0.64600000000000002,0.48299999999999998,0.48299999999999998,0.48499999999999999,0.48399999999999999,0.48,0.44500000000000001,0.47399999999999998,0.48,0.55600000000000005]
[16,0.28899999999999998,0.37,0.40600000000000003,0.40600000000000003,0.35,0.371,0.28799999999999998,{"$nulls":123},0.313]
[17,0.32700000000000001,0.317,0.29899999999999999]
[18,{"$nulls":151},0.433,0.42399999999999999,0.437,0.48599999999999999]
[19,0.33900000000000002]
[20,0.27900000000000003,0.29899999999999999,0.3]
[21,0.318,0.32,0.34399999999999997,0.31,0.27600000000000002,0.28999999999999998,0.29299999999999998,0.28499999999999998,0.65300000000000002,0.28299999999999997,0.27800000000000002,0.28699999999999998,0.27100000000000002,0.32400000000000001,0.30399999999999999,0.29799999999999999,0.30199999999999999,0.30099999999999999,0.27300000000000002,0.29899999999999999]
[22,0.37,0.32700000000000001,0.317,0.33700000000000002,0.443,0.35499999999999998]
[23,0.311,0.29599999999999999,0.28000000000000003,0.33100000000000002,0.30599999999999999,0.307,0.32800000000000001,0.41399999999999998,0.38900000000000001]
[24,0.29199999999999998,0.33300000000000002,0.29799999999999999,0.27,0.28100000000000003,0.28899999999999998,0.32500000000000001,0.32600000000000001]
[25]
[26]
[27]
[28]

{"sheet":"Figure 4a","index":6,"n_rows":8,"n_cols":4,"rows_kept":8,"cut":false,"hidden":false,"merged":[]}
["Individual datapoints for experiment run in duplicate"]
[null,"NT (3)","rTg4510 (3)","Tg4510 (3)"]
[null,0.96850000000000003,6.1970000000000001,1.0489999999999999]
[null,1.645,4.9340000000000002,2.0350000000000001]
[null,0.78879999999999995,1.7170000000000001,1.6879999999999999]
[null,0.90259999999999996,9.9329999999999998,1.903]
[null,0.48720000000000002,3.7890000000000001,1.782]
[null,0.4143,2.7440000000000002,1.8979999999999999]

{"sheet":"Figure 4b","index":7,"n_rows":11,"n_cols":4,"rows_kept":11,"cut":false,"hidden":false,"merged":[]}
["Individual datapoints for experiment run in triplicate"]
[null,"NT (3)","rTg4510 (3)","Tg4510 (3)"]
[null,0.28410000000000002,6.8699999999999997E-2,0.115]
[null,0.40529999999999999,7.2300000000000003E-2,0.13750000000000001]
[null,0.34460000000000002,8.0100000000000005E-2,0.1014]
[null,0.32129999999999997,0.14979999999999999,0.1258]
[null,0.45400000000000001,0.1734,0.16839999999999999]
[null,0.34,0.16850000000000001,8.7900000000000006E-2]
[null,0.2611,0.1105,0.1525]
[null,0.2185,0.1321,0.12909999999999999]
[null,0.2707,0.11990000000000001,0.14080000000000001]

{"sheet":"Figure 4c","index":8,"n_rows":8,"n_cols":4,"rows_kept":8,"cut":false,"hidden":false,"merged":[]}
["Individual data points for experiment run in duplicate"]
[null,"NT (3)","rTg4510 (3)","Tg4510 (3)"]
[null,1.073,0.61890000000000001,0.49249999999999999]
[null,1.681,0.55800000000000005,0.56410000000000005]
[null,1.546,0.38940000000000002,0.59470000000000001]
[null,1.0720000000000001,0.50490000000000002,0.58189999999999997]
[null,0.81269999999999998,0.53390000000000004,0.61060000000000003]
[null,0.95189999999999997,0.4637,0.56259999999999999]

{"sheet":"Figure 4d","index":9,"n_rows":8,"n_cols":4,"rows_kept":8,"cut":false,"hidden":false,"merged":[]}
["Individual data points for experiment run in duplicate"]
[null,"NT (3)","rTg4510 (3)","Tg4510 (3)"]
[null,0.1242,4.7300000000000002E-2,0.11559999999999999]
[null,0.38590000000000002,0.17860000000000001,0.1179]
[null,0.13730000000000001,9.4799999999999995E-2,0.1207]
[null,0.21190000000000001,0.2321,5.8099999999999999E-2]
[null,0.124,0.13600000000000001,0.1201]
[null,0.18190000000000001,0.1043,8.6400000000000005E-2]

{"sheet":"Figure 4e","index":10,"n_rows":19,"n_cols":14,"rows_kept":19,"cut":false,"hidden":false,"merged":[[1,2,1,4],[1,5,1,7],[1,8,1,10],[1,11,1,13],[8,2,8,4],[8,5,8,7],[8,8,8,10],[8,11,8,13]]}
["Plotted data"]
[null,null,"V1",null,null,"V2",null,null,"X1",null,null,"X2"]
[null,null,"Mean","SD","N","Mean","SD","N","Mean","SD","N","Mean","SD","N"]
[null,"NT (3)",0.86783299999999997,0.28773300000000002,3,0.32219999999999999,0.102033,3,1.189433,0.40706700000000001,3,0.19423299999999999,0.13139999999999999,3]
[null,"rTg4510 (3)",4.8860000000000001,8.2159999999999993,3,0.1195,0.1047,3,0.51149999999999995,0.22950000000000001,3,0.13220000000000001,0.18479999999999999,3]
[null,"Tg4510 (3)",1.726,0.98599999999999999,3,0.12870000000000001,8.0500000000000002E-2,3,0.56769999999999998,0.1181,3,0.1031,6.2600000000000003E-2,3]
[]
["Individual data points (normalized to positive calibrator within experiments)"]
[null,null,"V1 (duplicates)",null,null,"V2 (triplicates)",null,null,"X1 (duplicates)",null,null,"X2 (duplicates)"]
[null,null,"Tg Neg","rTg4510","Tg4510","Tg Neg","rTg4510","Tg4510","Tg Neg","rTg4510","Tg4510","Tg Neg","rTg4510","Tg4510"]
[null,null,0.96850000000000003,6.1970000000000001,1.0489999999999999,0.28410000000000002,6.8699999999999997E-2,0.115,1.073,0.61890000000000001,0.49249999999999999,0.1242,4.7300000000000002E-2,0.11559999999999999]
[null,null,1.645,4.9340000000000002,2.0350000000000001,0.40529999999999999,7.2300000000000003E-2,0.13750000000000001,1.681,0.55800000000000005,0.56410000000000005,0.38590000000000002,0.17860000000000001,0.1179]
[null,null,0.78879999999999995,1.7170000000000001,1.6879999999999999,0.34460000000000002,8.0100000000000005E-2,0.1014,1.546,0.38940000000000002,0.59470000000000001,0.13730000000000001,9.4799999999999995E-2,0.1207]
[null,null,0.90259999999999996,9.9329999999999998,1.903,0.32129999999999997,0.14979999999999999,0.1258,1.0720000000000001,0.50490000000000002,0.58189999999999997,0.21190000000000001,0.2321,5.8099999999999999E-2]
[null,null,0.48720000000000002,3.7890000000000001,1.782,0.45400000000000001,0.1734,0.16839999999999999,0.81269999999999998,0.53390000000000004,0.61060000000000003,0.124,0.13600000000000001,0.1201]
[null,null,0.4143,2.7440000000000002,1.8979999999999999,0.34,0.16850000000000001,8.7900000000000006E-2,0.95189999999999997,0.4637,0.56259999999999999,0.18190000000000001,0.1043,8.6400000000000005E-2]
[{"$nulls":5},0.2611,0.1105,0.1525]
[{"$nulls":5},0.2185,0.1321,0.12909999999999999]
[{"$nulls":5},0.2707,0.11990000000000001,0.14080000000000001]

{"sheet":"Figure 6b","index":11,"n_rows":34,"n_cols":18,"rows_kept":34,"cut":false,"hidden":false,"merged":[[1,16,1,17],[1,6,1,7],[1,8,1,9],[1,10,1,11],[1,12,1,13],[1,14,1,15]]}
["Tau histopathology scores"]
[{"$nulls":6},"MC1",null,"CP13",null,"AT8",null,"PHF1",null,"Biels",null,"PG5"]
[null,"Line","Gender","Tau ","CKTTA","Age (months)","Ctx","Hipp","Ctx","Hipp","Ctx","Hipp","Ctx","Hipp","Ctx","Hipp","Ctx","Hipp"]
[null,"rTg4510","F","+/-","+/-",2,"+","+","+","+","+","+","+","+","+","-","NA","NA"]
[null,"rTg4510","M","+/-","+/-",2,"+","-","-","-","+","+","-","-","+","-","NA","NA"]
[null,"rTg4510","M","+/-","+/-",2,"-","+","-","-","+","+","-","+","-","+","NA","NA"]
[null,"rT2","F","+/-","+/-",3,"-","-","NA","NA","-","-","-","-","-","-","-","-"]
[null,"rT2","F","+/-","+/-",3,"-","-","NA","NA","-","-","-","-","-","-","-","-"]
[null,"rT2","M","+/-","+/-",3,"-","-","NA","NA","-","-","-","-","-","-","-","-"]
[null,"rT2","M","+/-","+/-",3,"-","-","NA","NA","-","-","-","-","-","-","-","+"]
[null,"rT2/T2","F","+/+","+/-",2,"-","-","-","-","-","+","-","-","+","-","NA","NA"]
[null,"rT2/T2","F","+/+","+/-",2,"-","+","-","-","-","+","-","-","+","-","NA","NA"]
[null,"rT2/T2","M","+/+","+/-",2,"-","+","-","+","-","+","-","-","+","+","NA","NA"]
[null,"rT2/T2","M","+/+","+/-",2,"-","-","-","-","-","-","-","-","+","+","NA","NA"]
[null,"rTg4510","F","+/-","+/-",5,"++","+++","+++","+++","++","+++","++","+++","++","++","NA","NA"]
[null,"rTg4510","F","+/-","+/-",5,"++","+++","++","++","++","++","++","++","++","+","NA","NA"]
[null,"rTg4510","M","+/-","+/-",5,"++","++","++","++","++","++","-","-","++","++","NA","NA"]
[null,"rTg4510","M","+/-","+/-",5,"+","++","+","++","+","++","+","++","+","+","NA","NA"]
[null,"rT2","M","+/-","+/-",5,"-","-","NA","NA","-","-","-","-","-","-","-","-"]
[null,"rT2","M","+/-","+/-",5,"-","-","NA","NA","-","-","-","-","-","-","-","-"]
[null,"rT2/T2","F","+/+","+/-",5,"-","+","-","+","+","+","-","-","-","-","NA","NA"]
[null,"rT2/T2","M","+/+","+/-",5,"+","+","+","+","+","+","-","+","-","+","NA","NA"]
[null,"rT2/T2","M","+/+","+/-",5,"+","+","++","+","+","+","-","+","+","+","NA","NA"]
[null,"rTg4510","F","+/-","+/-",7,"+++","+++","+++","+++","+++","+++","+++","+++","+++","+++","NA","NA"]
[null,"rTg4510","F","+/-","+/-",7,"+++","+++","+++","+++","+++","+++","+++","+++","+++","+++","NA","NA"]
[null,"rTg4510","M","+/-","+/-",7,"+++","+++","+++","+++","+++","+++","+++","+++","+++","+++","NA","NA"]
[null,"rTg4510","M","+/-","+/-",7,"+++","+++","+++","+++","+++","+++","+++","+++","+++","+++","NA","NA"]
[null,"rT2","F","+/-","+/-",7,"-","-","NA","NA","-","+","-","-","-","-","+","+"]
[null,"rT2","F","+/-","+/-",7,"-","-","NA","NA","-","-","-","-","-","-","-","-"]
[null,"rT2","M","+/-","+/-",7,"+","-","NA","NA","-","++","-","++","-","+","-","++"]
[null,"rT2/T2","F","+/+","+/-",7,"+++","+++","+++","+++","+++","+++","++","+++","++","+++","NA","NA"]
[null,"rT2/T2","F","+/+","+/-",7,"++","++","++","+++","++","+++","++","++","++","++","NA","NA"]
[null,"rT2/T2","M","+/+","+/-",7,"++","+++","+++","+++","++","+++","++","+++","++","+++","NA","NA"]
[null,"rT2/T2","M","+/+","+/-",7,"++","+++","++","+++","++","+++","++","+++","++","+++","NA","NA"]

{"sheet":"Figure 7a","index":12,"n_rows":5,"n_cols":26,"rows_kept":5,"cut":false,"hidden":false,"merged":[[1,2,1,7],[1,8,1,13],[1,14,1,19],[1,20,1,25]]}
[]
[null,"Hours","Tau+/+tTA+/-",{"$nulls":5},"Tau+/+tTA-/- & Tau+/-tTA-/-",{"$nulls":5},"Tau+/-tTA+/-",{"$nulls":5},"Tau-/-tTA-/-"]
[null,2,2,{"$nulls":5},1,2,4.5,3,null,null,4,5,6,7,2,4,4,2,7,7,5,6]
[null,6,2,{"$nulls":5},2,4.5,4.5,5,null,null,6,4,5,7,6,6,5,5,7,7,6,6]
[null,24,2,{"$nulls":5},3,5,6,6,null,null,6,6,6,7,7,6,6,6,7,7,7,7]

{"sheet":"Figure 7b","index":13,"n_rows":5,"n_cols":26,"rows_kept":5,"cut":false,"hidden":false,"merged":[[1,2,1,7],[1,8,1,13],[1,14,1,19],[1,20,1,25]]}
[]
[null,"Hours","Tau+/+tTA+/-",{"$nulls":5},"Tau+/+tTA-/- & Tau+/-tTA-/-",{"$nulls":5},"Tau+/-tTA+/-",{"$nulls":5},"Tau-/-tTA-/-"]
[null,2,1,1,0.5,1.5,1,1,2,1.5,2,null,null,null,2,5,6,3,4,1,5,3,2,7,1,6]
[null,6,1.5,1,1,1.5,1,1,5,4,2.5,null,null,null,2,4,5,3,4,1,4,5,5,6,2,7]
[null,24,2,1,1,1.5,2,1,6,5,4,null,null,null,4,6,7,7,4,7,7,7,7,7,5,7]

{"sheet":"Figure 7c","index":14,"n_rows":4,"n_cols":28,"rows_kept":4,"cut":false,"hidden":false,"merged":[[1,2,1,14],[1,15,1,27]]}
[]
[null,null,"Tau+/+tTA+/-",{"$nulls":12},"Tau+/+tTA-/-"]
[null,"8.5M",14626.6,15334.3,23303.9,16870.900000000001,9319.65,4106.83,3327.79,{"$nulls":6},4498.5600000000004,3483,3737.64,4215.6000000000004,4194.05,5889.48,4000.59]
[null,"12.5M",4421.68,9550.35,4930.53,889.00099999999998,13.2157,737.93700000000001,3183.29,13282.2,4426.78,2724.4,null,null,null,5217.42,3073.71,3787.32,4890.4799999999996,4798.17,5362.5,4534.49,4549.7299999999996,5528.87,4155.71,5243.89,5075.76,3610.17]

{"sheet":"Figure 7d","index":15,"n_rows":4,"n_cols":28,"rows_kept":4,"cut":false,"hidden":false,"merged":[[1,2,1,14],[1,15,1,27]]}
[]
[null,null,"Tau+/+tTA+/-",{"$nulls":12},"Tau+/+tTA-/-"]
[null,"8.5M",427.09399999999999,521.85500000000002,570.37,526.19299999999998,423.35700000000003,420.48700000000002,370.77100000000002,{"$nulls":6},496.964,411.678,502.90300000000002,502.83600000000001,498.03100000000001,479.21300000000002,461.79500000000002]
[null,"12.5M",467.20100000000002,408.40800000000002,364.89100000000002,168.90199999999999,1.0677300000000001,126.92700000000001,396.26299999999998,511.64499999999998,416.149,335.26900000000001,null,null,null,549.95000000000005,436.904,465.666,492.69299999999998,474.14100000000002,499.49900000000002,452.452,438.77199999999999,542.14200000000005,468.93599999999998,512.57899999999995,532.93299999999999,468.00099999999998]

{"sheet":"Figure 7e","index":16,"n_rows":4,"n_cols":28,"rows_kept":4,"cut":false,"hidden":false,"merged":[[1,2,1,14],[1,15,1,27]]}
[]
[null,null,"Tau+/+tTA+/-",{"$nulls":12},"Tau+/+tTA-/-"]
[null,"8.5M",9.2081900000000001,9.1515599999999999,32.825499999999998,26.946200000000001,3.89235,12.222,4.1365499999999997,{"$nulls":6},8.6734100000000005,11.3088,15.280200000000001,11.2544,7.9061500000000002,13.9998,10.886200000000001]
[null,"12.5M",18.116099999999999,15.678900000000001,18.403199999999998,38.018500000000003,0,17.824999999999999,13.488300000000001,19.9511,14.301600000000001,4.1370100000000001,null,null,null,11.698,3.42489,13.6995,10.619400000000001,12.110799999999999,15.145099999999999,8.8513300000000008,4.0142300000000004,11.8216,9.4851600000000005,12.9323,14.390599999999999,6.5725100000000003]

{"sheet":"Suppl Fig 9b","index":17,"n_rows":35,"n_cols":15,"rows_kept":35,"cut":false,"hidden":false,"merged":[[0,1,0,4],[0,6,0,9],[0,11,0,14],[9,1,9,4],[9,6,9,9],[9,11,9,14],[18,1,18,4],[18,6,18,9],[18,11,18,14],[27,1,27,4],[27,6,27,9],[27,11,27,14]]}
[null,"MC1 2 months",{"$nulls":4},"MC1 5 months",{"$nulls":4},"MC1 7 months"]
[null,"rTg4510 CTL","rTg4510","rT2/T2 CTL","rT2/T2",null,"rTg4510 CTL","rTg4510","rT2/T2 CTL","rT2/T2",null,"rTg4510 CTL","rTg4510","rT2/T2 CTL","rT2/T2"]
[null,4.5370000000000002E-3,0.201045,1.1521999999999999E-2,0.32652199999999998,null,8.9079999999999993E-3,0.15268899999999999,1.3575E-2,0.19417400000000001,null,2.6865E-2,0.246417,2.0197E-2,0.44479099999999999]
[null,4.0369999999999998E-3,0.36155100000000001,7.4770000000000001E-3,0.40494999999999998,null,2.3029999999999999E-3,0.13997999999999999,1.3171E-2,0.361786,null,1.474E-3,0.23894299999999999,1.4012999999999999E-2,0.38601000000000002]
[null,1.0167000000000001E-2,0.248641,null,0.33075500000000002,null,2.9045000000000001E-2,0.209035,8.3850000000000001E-3,0.45508399999999999,null,1.8749999999999999E-2,0.35148800000000002,null,0.46492299999999998]
[null,1.1667E-2,null,null,0.215366,null,2.1967E-2,0.20394599999999999,3.8031000000000002E-2,null,null,1.3273999999999999E-2]
[{"$nulls":6},9.6919999999999992E-3,null,1.6352999999999999E-2,null,null,1.5131E-2]
[{"$nulls":6},1.4789999999999999E-2,null,1.3027E-2]
[]
[null,"AT8 2 months",{"$nulls":4},"AT8 5 months",{"$nulls":4},"AT8 7 months"]
[null,"rTg4510 CTL","rTg4510","rT2/T2 CTL","rT2/T2",null,"rTg4510 CTL","rTg4510","rT2/T2 CTL","rT2/T2",null,"rTg4510 CTL","rTg4510","rT2/T2 CTL","rT2/T2"]
[null,0.198354,0.115582,0.16761400000000001,5.9547999999999997E-2,null,0.204322,0.16094800000000001,0.210205,0.15518899999999999,null,0.29467599999999999,0.35023399999999999,0.111217,0.17194799999999999]
[null,0.180364,7.2049999999999996E-3,9.536E-2,9.5142000000000004E-2,null,0.11744499999999999,0.207903,0.18689800000000001,0.21710299999999999,null,0.112664,0.12928300000000001,3.3922000000000001E-2,0.31970300000000001]
[null,7.9197000000000004E-2,4.1946999999999998E-2,null,0.10064099999999999,null,0.109057,3.5949000000000002E-2,6.1037000000000001E-2,8.6393999999999999E-2,null,0.15759999999999999,0.23850399999999999,null,0.11340500000000001]
[null,6.3388E-2,null,null,5.7671E-2,null,0.1431,0.176925,0.20763899999999999,null,null,0.18060200000000001,null,null,0.13572000000000001]
[{"$nulls":6},0.10391499999999999,null,0.12085600000000001,null,null,8.1903000000000004E-2]
[{"$nulls":6},0.10918799999999999,null,0.126334]
[]
[null,"CP13 2 months",{"$nulls":4},"CP13 5 months",{"$nulls":4},"CP13 7 months"]
[null,"rTg4510 CTL","rTg4510","rT2/T2 CTL","rT2/T2",null,"rTg4510 CTL","rTg4510","rT2/T2 CTL","rT2/T2",null,"rTg4510 CTL","rTg4510","rT2/T2 CTL","rT2/T2"]
[null,0.106339,0.73810399999999998,5.2443999999999998E-2,0.85886399999999996,null,4.2168999999999998E-2,0.41578399999999999,3.5757999999999998E-2,0.64338899999999999,null,5.6498E-2,0.399891,1.3004100000000001E-4,0.56716200000000005]
[null,7.3630000000000001E-2,0.74384300000000003,5.4580999999999998E-2,0.909937,null,6.2157999999999998E-2,0.53757600000000005,0,0.75004636999999996,null,3.5060000000000001E-2,0.317332,2.4698300000000001E-3,0.37748300000000001]
[null,0.22034899999999999,0.52072079999999998,null,0.951318,null,3.9560999999999999E-2,0.56025000000000003,7.9299999999999998E-4,0.19444444399999999,null,2.5826000000000002E-2,0.211701325,null,0.29224294699999998]
[null,1.76813E-5,null,null,6.4675927999999994E-2,null,2.4913000000000001E-2,0.42908217900000001,8.4181000000000006E-2,null,null,6.1809999999999999E-3,null,null,0.701910853]
[{"$nulls":6},7.8001899999999996E-5,null,3.5468799999999998E-4,null,null,6.99711E-4]
[{"$nulls":6},0,null,2.4819799999999998E-4]
[]
[null,"PHF1 2 months",{"$nulls":4},"PHF1 5 months",{"$nulls":4},"PHF1 7 months"]
[null,"rTg4510 CTL","rTg4510","rT2/T2 CTL","rT2/T2",null,"rTg4510 CTL","rTg4510","rT2/T2 CTL","rT2/T2",null,"rTg4510 CTL","rTg4510","rT2/T2 CTL","rT2/T2"]
[null,0.17782000000000001,1.7805770000000001,0.26389299999999999,1.8517920000000001,null,0.124513,2.0454249999999998,0.180092,1.095531,null,0.18837000000000001,1.441605,0.38359700000000002,2.095634]
[null,0.106974,0.57972299999999999,0.19011600000000001,1.796557,null,0.170853,0.786103,5.0826000000000003E-2,1.070643,null,0.17550299999999999,1.3409979999999999,0.59148199999999995,0.88959999999999995]
[null,0.53828100000000001,2.080066,null,1.1144320000000001,null,0.10403999999999999,1.146015,3.0106000000000001E-2,6.1952379999999998,null,8.6895E-2,1.9919800000000001,null,5.1394890000000002]
[null,0.33288099999999998,null,null,3.5679630000000002,null,0.109685,1.6003849999999999,0.16753699999999999,null,null,7.7601000000000003E-2,null,null,4.6063850000000004]
[{"$nulls":6},0.283636,null,0.22192100000000001,null,null,0.25632199999999999]
[{"$nulls":6},0.336534,null,0.26189899999999999]

{"sheet":"Suppl Fig 10b","index":18,"n_rows":16,"n_cols":14,"rows_kept":16,"cut":false,"hidden":false,"merged":[[1,2,1,5],[1,6,1,9],[1,10,1,13],[5,2,5,5],[5,6,5,9],[5,10,5,13],[9,2,9,5],[9,6,9,9],[9,10,9,13],[13,2,13,5],[13,6,13,9],[13,10,13,13]]}
[]
["MC1",null,"2M",null,null,null,"5M",null,null,null,"7M"]
[null,"rTg4510",0.55246600000000001,0.50175000000000003,0.29749999999999999,null,0.49022700000000002,0.39247199999999999,0.34107799999999999,0.39243099999999997,0.50265000000000004,0.451845,0.44774399999999998]
[null,"rT2/T2",0.548898,0.52865200000000001,0.41294799999999998,0.27067999999999998,0.43664700000000001,0.73236500000000004,0.369645,null,0.49952800000000003,0.483705,0.228327,0.44430900000000001]
[]
["AT8",null,"2M",null,null,null,"5M",null,null,null,"7M"]
[null,"rTg4510",0.21684,9.5024999999999998E-2,6.2126000000000001E-2,null,0.30664200000000003,0.25587599999999999,0.16466900000000001,8.6001999999999995E-2,0.207843,0.19441600000000001,0.13291700000000001]
[null,"rT2/T2",0.12527199999999999,9.1785000000000005E-2,5.6120999999999997E-2,7.2905999999999999E-2,0.411269,0.25965500000000002,0.100949,null,0.26658199999999999,0.31957999999999998,1.2222E-2,0.16259499999999999]
[]
["CP13",null,"2M",null,null,null,"5M",null,null,null,"7M"]
[null,"rTg4510",0.21088999999999999,0.28868899999999997,0.476242,null,0.192249,0.18104100000000001,0.51481500000000002,0.42089399999999999,0.149724,0.52142599999999995,0.50673500000000005]
[null,"rT2/T2",0.24207500000000001,0.37862699999999999,0.54612400000000005,0.349412,0.20019300000000001,0.21092900000000001,0.458534,null,0.24343200000000001,0.25234899999999999,0.47671200000000002,0.37705]
[]
["PHF1",null,"2M",null,null,null,"5M",null,null,null,"7M"]
[null,"rTg4510",0.68094699999999997,0.60263100000000003,1.13788,null,0.90407599999999999,0.88239299999999998,1.168981,0.939438,0.85521199999999997,1.1765190000000001,1.1889879999999999]
[null,"rT2/T2",0.83625700000000003,0.88637200000000005,0.90578000000000003,0.98367800000000005,0.64856599999999998,0.63246599999999997,0.97176499999999999,null,0.81206,0.85455700000000001,0.97276799999999997,0.90223600000000004]

{"sheet":"Suppl Fig 11","index":19,"n_rows":17,"n_cols":14,"rows_kept":17,"cut":false,"hidden":false,"merged":[[9,2,9,6],[9,7,9,11],[13,2,13,5],[13,6,13,9],[1,2,1,5],[1,6,1,9],[5,2,5,7],[5,8,5,13]]}
["2 MONTHS"]
[null,null,"rTg4510",null,null,null,"rT2/T2"]
[null,"sib CTL",0,0,0,0,0,0]
[null,"TauP301L",0,0,0,null,0,0,0,0]
["5 MONTHS"]
[null,null,"rTg4510",{"$nulls":5},"rT2/T2"]
[null,"sib CTL",0,0,0,0,0,0,0,0,0,0,0,0]
[null,"TauP301L",0.1,0,0,1.8057606E-2,null,null,0,0,0]
["7 MONTHS"]
[null,null,"rTg4510",{"$nulls":4},"rT2/T2"]
[null,"sib CTL",0,0,0,0,0,0,0]
[null,"TauP301L",0.17,8.0302129E-2,0.52574057100000005,null,null,0.33,0.38141371400000001,0.40336287199999998,4.8898502000000003E-2]
["COMBINED"]
[null,null,"rTg4510",null,null,null,"rT2/T2"]
[null,2,0,0,0,null,0,0,0,0]
[null,5,0.1,0,0,1.8057606E-2,0,0,0]
[null,7,0.17,8.0302129E-2,0.52574057100000005,null,0.33,0.38141371400000001,0.40336287199999998,4.8898502000000003E-2]

{"sheet":"Suppl Fig 12a","index":20,"n_rows":18,"n_cols":3,"rows_kept":18,"cut":false,"hidden":false,"merged":[]}
[]
["rT2 (3)","rT2/T2 (10)","rTg4510 (11)"]
[70.134510000000006,140.0181,102.5535714]
[85.489819999999995,107.3766,98.910714290000001]
[53.904299999999999,109.0838,113.4107143]
[64.474469999999997,163.221,83.267857140000004]
[64.028090000000006,115.8113,92.446428569999995]
[42.519939999999998,89.587400000000002,109.4821429]
[null,78.218760000000003,90.116727269999998]
[null,106.1572,116.6015455]
[null,79.422389999999993,144.7353636]
[null,101.8343,89.108090910000001]
[null,null,137.53154549999999]
[null,null,69.819909089999996]
[null,null,76.27054545]
[null,null,72.975454549999995]
[]
["Note: rT2 samples and a subset of rTg4510 samples were run in two separate experiments, and data points from each individual experiment are included"]

{"sheet":"Suppl Fig 12b","index":21,"n_rows":12,"n_cols":4,"rows_kept":12,"cut":false,"hidden":false,"merged":[]}
["tTA (6)","rT2 (7)","rT2/T2 (11)","rTg4510 (8)"]
[6.9761000000000004E-2,0.86898900000000001,1.3677630000000001,0.88067700000000004]
[0.133438,1.1689259999999999,1.391467,1.4459310000000001]
[7.4460999999999999E-2,0.47100900000000001,1.325947,1.035434]
[7.9804E-2,0.83921299999999999,1.086635,0.73173900000000003]
[6.1697000000000002E-2,0.912493,1.737088,0.40359]
[0.117407,0.71770999999999996,2.1057459999999999,1.3178080000000001]
[null,0.344557,1.7171639999999999,2.100104]
[null,null,0.99201300000000003,0.53513999999999995]
[null,null,1.3994420000000001]
[null,null,1.3812789999999999]
[null,null,2.1828349999999999]